{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T18:16:05Z","timestamp":1790705765139,"version":"4.1.0"},"reference-count":21,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2016,12,1]],"date-time":"2016-12-01T00:00:00Z","timestamp":1480550400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","trasci.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transfusion and Apheresis Science"],"published-print":{"date-parts":[[2016,12]]},"DOI":"10.1016\/j.transci.2016.08.005","type":"journal-article","created":{"date-parts":[[2016,9,30]],"date-time":"2016-09-30T14:02:53Z","timestamp":1475244173000},"page":"318-322","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"title":["Differentiation of pernicious anemia from thrombotic thrombocytopenic purpura: The clinical value of subtle pathologic findings"],"prefix":"10.1016","volume":"55","author":[{"given":"Daniel W.","family":"Abbott","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kenneth D.","family":"Friedman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Matthew S.","family":"Karafin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.transci.2016.08.005_bib0010","doi-asserted-by":"crossref","first-page":"R273","DOI":"10.1186\/cc13115","article-title":"The prognostic value of ADAMTS13 (a disintegrin and metalloprotease with thrombospondin type 1 repeats, member 13) deficiency in septic shock patients involves interleukin-6 and is not dependent on disseminated intravascular coagulation","volume":"17","author":"Peigne","year":"2013","journal-title":"Crit Care"},{"key":"10.1016\/j.transci.2016.08.005_bib0015","first-page":"15","article-title":"Therapeutic dilemma in the management of a patient with the clinical picture of TTP and severe B12 deficiency","volume":"1","author":"Walter","year":"2015","journal-title":"BMC Hematol"},{"issue":"1","key":"10.1016\/j.transci.2016.08.005_bib0020","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1111\/trf.13285","article-title":"To treat or not to treat: a rare case of pseudo-thrombotic thrombocytopenic purpura in a Jehovah's Witness","volume":"56","author":"Malla","year":"2016","journal-title":"Transfusion"},{"key":"10.1016\/j.transci.2016.08.005_bib0025","series-title":"Hematology: basic principles and practice","first-page":"1925","article-title":"Thrombotic thrombocytopenic purpura and the hemolytic uremic syndrome","author":"McCrae","year":"2013"},{"key":"10.1016\/j.transci.2016.08.005_bib0030","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1111\/j.1365-2257.2006.00755.x","article-title":"Current hematological findings in cobalamin deficiency. A study of 201 consecutive patients with documented cobalamin deficiency","volume":"28","author":"Andres","year":"2006","journal-title":"Clin Lab Haematol"},{"issue":"7","key":"10.1016\/j.transci.2016.08.005_bib0035","doi-asserted-by":"crossref","first-page":"1203","DOI":"10.1007\/s00467-015-3110-x","article-title":"Nephrotic syndrome and thrombotic microangiopathy caused by cobalamin C deficiency","volume":"30","author":"Koenig","year":"2015","journal-title":"Pediatr Nephrol"},{"issue":"11","key":"10.1016\/j.transci.2016.08.005_bib0040","doi-asserted-by":"crossref","first-page":"926","DOI":"10.1111\/jpc.12619","article-title":"2-year-old girl with pancytopenia due to vitamin B12 (cobalamin) deficiency","volume":"50","author":"Ho","year":"2014","journal-title":"J Paediatr Child Health"},{"key":"10.1016\/j.transci.2016.08.005_bib0045","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1093\/qjmed\/hct142","article-title":"Hemolysis and schistocytes in the emergency department: consider pseudothrombotic microangiopathy related to B12 deficiency","volume":"106","author":"Noel","year":"2013","journal-title":"Q J Med"},{"issue":"6","key":"10.1016\/j.transci.2016.08.005_bib0050","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1093\/ajcp\/66.6.953","article-title":"Reduced erythrocytic deformability in megaloblastic anemia","volume":"66","author":"Ballas","year":"1976","journal-title":"Am J Clin Pathol"},{"key":"10.1016\/j.transci.2016.08.005_bib0055","series-title":"Hematology, basic principles and practice","first-page":"519","article-title":"Megaloblastic anemias","author":"Antony","year":"2005"},{"issue":"22","key":"10.1016\/j.transci.2016.08.005_bib0060","doi-asserted-by":"crossref","first-page":"2113","DOI":"10.1001\/jama.281.22.2113","article-title":"Impairment of endothelial functions by acute hyperhomocysteinemia and reversal by antioxidant vitamins","volume":"281","author":"Nappo","year":"1999","journal-title":"JAMA"},{"key":"10.1016\/j.transci.2016.08.005_bib0065","doi-asserted-by":"crossref","first-page":"912","DOI":"10.1006\/bbrc.1996.1449","article-title":"The hemolytic activity of homocysteine is increased by the activated polymorphonuclear leukocytes","volume":"226","author":"Olinescu","year":"1996","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.transci.2016.08.005_bib0070","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.bbadis.2004.08.005","article-title":"A role for homocysteine increase in haemolysis of megaloblastic anaemias due to vitamin B(12) and folate deficiency: results from an in vitro experience","volume":"1739","author":"Ventura","year":"2004","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.transci.2016.08.005_bib0075","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1751-553X.2011.01380.x","article-title":"ICSH recommendations for identification, diagnostic value and quantification of schistocytes","volume":"34","author":"Zini","year":"2012","journal-title":"Int. J Lab Hematol"},{"issue":"10","key":"10.1016\/j.transci.2016.08.005_bib0080","doi-asserted-by":"crossref","first-page":"472","DOI":"10.4297\/najms.2011.3472.","article-title":"Pseudo-thrombotic thrombocytopenic purpura: a rare presentation of pernicious anemia","volume":"3","author":"Tadakamalla","year":"2011","journal-title":"N Am J Med Sci"},{"issue":"5","key":"10.1016\/j.transci.2016.08.005_bib0085","doi-asserted-by":"crossref","first-page":"988","DOI":"10.1111\/ped.12718","article-title":"Neglect-induced pseudo-thrombotic thrombocytopenic purpura due to vitamin B12 deficiency","volume":"57","author":"Asano","year":"2015","journal-title":"Pediatr Int"},{"issue":"11","key":"10.1016\/j.transci.2016.08.005_bib0090","doi-asserted-by":"crossref","first-page":"1844","DOI":"10.1182\/blood-2014-03-562488","article-title":"Severe vitamin B12 deficiency mimicking thrombotic thrombocytopenic purpura","volume":"124","author":"Routh","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.transci.2016.08.005_bib0095","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1002\/pbc.21788","article-title":"Severe vitamin B-12 deficiency in a child mimicking thrombotic thrombocytopenia purpura","volume":"52","author":"Dimond","year":"2009","journal-title":"Pediatr Blood Cancer"},{"issue":"3","key":"10.1016\/j.transci.2016.08.005_bib0100","doi-asserted-by":"crossref","DOI":"10.3390\/nu8030118","article-title":"Associations between vitamin B-12 status and oxidative stress and inflammation in diabetic vegetarians and omnivores","volume":"8","author":"Lee","year":"2016","journal-title":"Nutrients"},{"key":"10.1016\/j.transci.2016.08.005_bib0105","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1182\/blood-2004-01-0107","article-title":"Effects of inflammatory cytokines on the release and cleavage of the endothelial cell-derived ultralarge von Willebrand factor multimers under flow","volume":"104","author":"Bernardo","year":"2004","journal-title":"Blood"},{"issue":"12","key":"10.1016\/j.transci.2016.08.005_bib0110","doi-asserted-by":"crossref","first-page":"2525","DOI":"10.1111\/j.1537-2995.2012.03646.x","article-title":"Decreasing frequency of plasma exchange complications in patients treated for thrombotic thrombocytopenic purpura-hemolytic uremic syndrome, 1996 to 2011","volume":"52","author":"Som","year":"2012","journal-title":"Transfusion"}],"container-title":["Transfusion and Apheresis Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1473050216301227?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1473050216301227?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,8]],"date-time":"2018-09-08T01:52:59Z","timestamp":1536371579000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1473050216301227"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2016,12]]}},"alternative-id":["S1473050216301227"],"URL":"https:\/\/doi.org\/10.1016\/j.transci.2016.08.005","relation":{},"ISSN":["1473-0502"],"issn-type":[{"value":"1473-0502","type":"print"}],"subject":[],"published":{"date-parts":[[2016,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Differentiation of pernicious anemia from thrombotic thrombocytopenic purpura: The clinical value of subtle pathologic findings","name":"articletitle","label":"Article Title"},{"value":"Transfusion and Apheresis Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.transci.2016.08.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}