{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:13:56Z","timestamp":1786997636686,"version":"build-2736575974"},"reference-count":15,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","trasci.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transfusion and Apheresis Science"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.transci.2022.103417","type":"journal-article","created":{"date-parts":[[2022,3,3]],"date-time":"2022-03-03T02:25:33Z","timestamp":1646274333000},"page":"103417","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Can therapeutic plasma exchange be life-saving in life-threatening manganese intoxication?"],"prefix":"10.1016","volume":"61","author":[{"given":"Emel","family":"Uyar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Esra","family":"Gurkas","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aysel Unlusoy","family":"Aksu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Serhat","family":"Emeksiz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cigdem Seher","family":"Kasapkara","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nadide Basak","family":"Gulleroglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ikbal Ok","family":"Bozkaya","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kader Karl\u0131","family":"Oguz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"3","key":"10.1016\/j.transci.2022.103417_bib1","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1007\/s40572-015-0056-x","article-title":"Manganese toxicity upon overexposure: a decade in review","volume":"2","author":"O\u2019Neal","year":"2015","journal-title":"Curr Environ Health Rep"},{"issue":"1","key":"10.1016\/j.transci.2022.103417_bib2","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1186\/s40360-016-0099-0","article-title":"Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies","volume":"17","author":"Peres","year":"2016","journal-title":"BMC Pharmacol Toxicol"},{"issue":"9","key":"10.1016\/j.transci.2022.103417_bib3","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.2741\/4665","article-title":"Manganese metabolism in humans","volume":"23","author":"Chen","year":"2018","journal-title":"Front Biosci"},{"key":"10.1016\/j.transci.2022.103417_bib4","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1212\/WNL.38.4.550","article-title":"Chronic exposure to the fungicide maneb may produce symptoms and signs of CNS manganese intoxication","volume":"38","author":"Ferraz","year":"1988","journal-title":"Neurology"},{"key":"10.1016\/j.transci.2022.103417_bib5","doi-asserted-by":"crossref","first-page":"1714","DOI":"10.1016\/S0891-5849(02)01169-3","article-title":"Catalysis of catechol oxidation by metal-dithiocarba- mate complexes in pesticides","volume":"33","author":"Fitsanakis","year":"2002","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.transci.2022.103417_bib6","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1002\/ana.410360611","article-title":"Manganese intox- ication and chronic liver failure","volume":"36","author":"Hauser","year":"1994","journal-title":"Ann Neurol"},{"key":"10.1016\/j.transci.2022.103417_bib7","doi-asserted-by":"crossref","first-page":"813","DOI":"10.1097\/01.ftd.0000243964.90340.cc","article-title":"Life threatening central nervous system manifestations and hypothermia due to maneb intoxication in a child: a case report","volume":"28","author":"de Tollenaer","year":"2006","journal-title":"Ther Drug Monit"},{"issue":"12","key":"10.1016\/j.transci.2022.103417_bib8","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1289\/ehp.1307918","article-title":"Neurobehavioral function in school-age children exposed to manganese in drinking water","volume":"122","author":"Oulhote","year":"2014","journal-title":"Environ Health Perspect"},{"issue":"1","key":"10.1016\/j.transci.2022.103417_bib9","doi-asserted-by":"crossref","first-page":"138","DOI":"10.1289\/ehp.1002321","article-title":"Intellectual impairment in school-age children exposed to manganese from drinking water","volume":"119","author":"Bouchard","year":"2011","journal-title":"Environ Health Perspect"},{"key":"10.1016\/j.transci.2022.103417_bib10","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1002\/nbm.2891","article-title":"Regional specificity of manganese accumulation and clearance in the mouse brain: implications for manganese-enhanced MRI","volume":"26","author":"Grunecker","year":"2013","journal-title":"NMR Biomed"},{"key":"10.1016\/j.transci.2022.103417_bib11","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.3181\/0903-RM-118","article-title":"Relationship between changes in brain MRI and 1H-MRS, severity of chronic liver damage, and recovery after liver transplantation","volume":"234","author":"Long","year":"2009","journal-title":"Exp Biol Med"},{"issue":"2","key":"10.1016\/j.transci.2022.103417_bib12","doi-asserted-by":"crossref","first-page":"93","DOI":"10.14802\/jmd.20123","article-title":"Manganese and movement disorders: a review","volume":"14","author":"Kulshreshtha","year":"2021","journal-title":"J Movement Disord"},{"key":"10.1016\/j.transci.2022.103417_bib13","series-title":"Toxicology of Metals","first-page":"487","article-title":"Chelation therapies for metal intoxication","author":"Angle","year":"1996"},{"issue":"7","key":"10.1016\/j.transci.2022.103417_bib14","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.3390\/ijerph7072745","article-title":"Chelation in metal intoxication","volume":"7","author":"Flora","year":"2010","journal-title":"Int J Environ Res Public Health"},{"key":"10.1016\/j.transci.2022.103417_bib15","doi-asserted-by":"crossref","first-page":"11601","DOI":"10.1038\/ncomms11601","article-title":"Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia","volume":"7","author":"Tuschl","year":"2016","journal-title":"Nat Commun"}],"container-title":["Transfusion and Apheresis Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1473050222000842?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1473050222000842?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,26]],"date-time":"2025-10-26T08:53:41Z","timestamp":1761468821000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1473050222000842"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":15,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2022,8]]}},"alternative-id":["S1473050222000842"],"URL":"https:\/\/doi.org\/10.1016\/j.transci.2022.103417","relation":{},"ISSN":["1473-0502"],"issn-type":[{"value":"1473-0502","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Can therapeutic plasma exchange be life-saving in life-threatening manganese intoxication?","name":"articletitle","label":"Article Title"},{"value":"Transfusion and Apheresis Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.transci.2022.103417","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"103417"}}