{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T21:32:52Z","timestamp":1786483972581,"version":"build-2736575974"},"reference-count":16,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","trasci.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transfusion and Apheresis Science"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.transci.2026.104492","type":"journal-article","created":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T16:02:50Z","timestamp":1784044970000},"page":"104492","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Baseline-dependent immunometabolic effects of low-volume plasma exchange on inflammation and iron homeostasis in metabolic syndrome"],"prefix":"10.1016","volume":"65","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2014-3220","authenticated-orcid":false,"given":"Vjeroslava","family":"Slavi\u0107","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danijela","family":"Ran\u0111elovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gordana","family":"Rajovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tanja","family":"Antunovi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nevena Terzi\u0107","family":"Stani\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jelena","family":"Boljevi\u0107","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.transci.2026.104492_bib1","doi-asserted-by":"crossref","first-page":"1640","DOI":"10.1161\/CIRCULATIONAHA.109.192644","volume":"120","author":"Alberti","year":"2009","journal-title":"Circulation"},{"key":"10.1016\/j.transci.2026.104492_bib2","doi-asserted-by":"crossref","first-page":"E746","DOI":"10.1152\/ajpendo.00355.2025","article-title":"Gut-derived lipopolysaccharides and metabolic endotoxemia: a critical review","volume":"329","author":"Chen","year":"2025","journal-title":"Am J Physiol Endocrinol Metab"},{"key":"10.1016\/j.transci.2026.104492_bib3","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2020.594150","article-title":"Role of metabolic endotoxemia in systemic inflammation and potential interventions","volume":"11","author":"Mohammad","year":"2021","journal-title":"Front Immunol"},{"key":"10.1016\/j.transci.2026.104492_bib4","article-title":"Effects of dietary intervention on inflammatory markers in metabolic syndrome: a systematic review and meta-analysis","volume":"9","author":"Wang","year":"2022","journal-title":"Front Nutr"},{"key":"10.1016\/j.transci.2026.104492_bib5","doi-asserted-by":"crossref","first-page":"18975","DOI":"10.1074\/jbc.R115.650150","article-title":"Regulation of iron metabolism by hepcidin under conditions of inflammation","volume":"290","author":"Schmidt","year":"2015","journal-title":"J Biol Chem"},{"key":"10.1016\/j.transci.2026.104492_bib6","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1111\/eci.12032","article-title":"Iron homeostasis in the metabolic syndrome","volume":"43","author":"Datz","year":"2013","journal-title":"Eur J Clin Invest"},{"key":"10.1016\/j.transci.2026.104492_bib7","doi-asserted-by":"crossref","first-page":"224","DOI":"10.3390\/nu18020224","article-title":"Vitamin D Deficiency Mediates the Link Between Dietary Patterns, Inflammatory Biomarkers, and Iron Status Indicators (Ferritin and Hemoglobin) in Metabolic Syndrome","volume":"18","author":"Cortes-\u00c1lvarez","year":"2026","journal-title":"Nutrients"},{"key":"10.1016\/j.transci.2026.104492_bib8","doi-asserted-by":"crossref","first-page":"328","DOI":"10.3390\/biomedicines11020328","article-title":"Therapeutic plasma exchange in certain immune-mediated neurological disorders: focus on a novel nanomembrane-based technology","volume":"11","author":"Tonev","year":"2023","journal-title":"Biomedicines"},{"key":"10.1016\/j.transci.2026.104492_bib9","doi-asserted-by":"crossref","first-page":"801","DOI":"10.1097\/01.CCM.0000114997.39857.69","article-title":"Hemoadsorption removes tumor necrosis factor, interleukin-6, and interleukin-10, reduces NF-\u03baB DNA binding, and improves survival in a model of severe sepsis","volume":"32","author":"Kellum","year":"2004","journal-title":"Crit Care Med"},{"key":"10.1016\/j.transci.2026.104492_bib10","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1002\/cbf.2835","article-title":"New perspectives on the vitamin D binding protein","volume":"30","author":"Chun","year":"2012","journal-title":"Cell Biochem Funct"},{"key":"10.1016\/j.transci.2026.104492_bib11","doi-asserted-by":"crossref","first-page":"2486","DOI":"10.1001\/jama.285.19.2486","article-title":"Executive summary of the third report of the national cholesterol education program (NCEP) expert panel (Adult treatment panel III)","volume":"285","author":"Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults","year":"2001","journal-title":"JAMA"},{"key":"10.1016\/j.transci.2026.104492_bib12","doi-asserted-by":"crossref","first-page":"e17","DOI":"10.5114\/amsad\/216575","article-title":"Therapeutic role of low-volume plasma exchange in modulating lipopolysaccharide-binding protein and inflammatory pathways in metabolic syndrome","volume":"11","author":"Slavic","year":"2026","journal-title":"Arch Med Sci Atheroscler Dis"},{"issue":"1","key":"10.1016\/j.transci.2026.104492_bib13","first-page":"17","article-title":"Exploring the impact of nanomembrane-based low-volume plasma exchange on gut barrier integrity in metabolic syndrome: a prospective study","author":"Slavic","year":"2024","journal-title":"Int J Innov Med ("},{"key":"10.1016\/j.transci.2026.104492_bib14","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.cca.2019.06.019","article-title":"Metabolic syndrome is an inflammatory disorder: A conspiracy between adipose tissue and phagocytes","volume":"496","author":"Reddy","year":"2019","journal-title":"Clin Chim Acta"},{"key":"10.1016\/j.transci.2026.104492_bib15","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1093\/qjmed\/hct208","article-title":"Plasma exchange induces vitamin D deficiency","volume":"107","author":"Hiemstra","year":"2014","journal-title":"QJM"},{"issue":"10384","key":"10.1016\/j.transci.2026.104492_bib16","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1016\/S0140-6736(23)00215-5","article-title":"Inflammation and cholesterol as predictors of cardiovascular events among patients receiving statin therapy: a collaborative analysis of three randomised trials","volume":"401","author":"Ridker","year":"2023","journal-title":"Lancet"}],"container-title":["Transfusion and Apheresis Science"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1473050226001242?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1473050226001242?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,8,11]],"date-time":"2026-08-11T21:09:47Z","timestamp":1786482587000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1473050226001242"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":16,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,8]]}},"alternative-id":["S1473050226001242"],"URL":"https:\/\/doi.org\/10.1016\/j.transci.2026.104492","relation":{},"ISSN":["1473-0502"],"issn-type":[{"value":"1473-0502","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Baseline-dependent immunometabolic effects of low-volume plasma exchange on inflammation and iron homeostasis in metabolic syndrome","name":"articletitle","label":"Article Title"},{"value":"Transfusion and Apheresis Science","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.transci.2026.104492","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"104492"}}