{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:42:27Z","timestamp":1758588147740,"version":"3.44.0"},"reference-count":24,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,7,1]],"date-time":"2010-07-01T00:00:00Z","timestamp":1277942400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2011,8,6]],"date-time":"2011-08-06T00:00:00Z","timestamp":1312588800000},"content-version":"vor","delay-in-days":401,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/501100001807","name":"Funda\u00e7\u00e3o de Amparo \u00e0 Pesquisa do Estado de S\u00e3o Paulo","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001807","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transplantation Proceedings"],"published-print":{"date-parts":[[2010,7]]},"DOI":"10.1016\/j.transproceed.2010.05.112","type":"journal-article","created":{"date-parts":[[2010,8,7]],"date-time":"2010-08-07T04:26:46Z","timestamp":1281155206000},"page":"2092-2096","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Pancreas Transplantation Prevents Morphologic and Ultrastructural Changes in Pulmonary Parenchyma of Alloxan-Induced Diabetic Rats"],"prefix":"10.1016","volume":"42","author":[{"given":"C.T.","family":"Spadella","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"O.A.X.","family":"Suarez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.N.","family":"Lucchesi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.J.M.","family":"Cataneo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.transproceed.2010.05.112_bib1","first-page":"223","article-title":"Cross-section study of pulmonary function in patients with insulin-dependent diabetes mellitus","volume":"135","author":"Sandler","year":"1987","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.transproceed.2010.05.112_bib2","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1378\/chest.114.4.1033","article-title":"Reduction of diffusion capacity for carbon monoxide in diabetic patients","volume":"114","author":"Ljubic","year":"1998","journal-title":"Chest"},{"key":"10.1016\/j.transproceed.2010.05.112_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1002\/ppul.10399","article-title":"Lung function in children with diabetes mellitus","volume":"37","author":"Cazzato","year":"2004","journal-title":"Pediatr Pulmonol"},{"key":"10.1016\/j.transproceed.2010.05.112_bib4","doi-asserted-by":"crossref","first-page":"1385","DOI":"10.1001\/archinte.1990.00390190051006","article-title":"Is the lung a \u201ctarget organ\u201d in diabetes mellitus?","volume":"150","author":"Sandler","year":"1990","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.transproceed.2010.05.112_bib5","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1164\/arrd.1983.128.1.125","article-title":"Changes and lung morphological features in elasticity caused by streptozotocin-induced diabetes mellitus in growing rats","volume":"128","author":"Kida","year":"1983","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.transproceed.2010.05.112_bib6","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1159\/000029331","article-title":"Diabetes mellitus induces a thickening of the pulmonary basal lamina","volume":"66","author":"Weynand","year":"1999","journal-title":"Respiration"},{"key":"10.1016\/j.transproceed.2010.05.112_bib7","first-page":"1135","article-title":"Alterations in the ultrastructure of non-ciliated bronchiolar epithelial (clara) cells by streptozotocin-induced diabetes rats","volume":"120","author":"Plopper","year":"1979","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.transproceed.2010.05.112_bib8","first-page":"143","article-title":"Alteration in granular (type II) pneumocyte ultrastructure by streptozotocin-induced diabetes in the rat","volume":"38","author":"Plopper","year":"1978","journal-title":"Lab Invest"},{"key":"10.1016\/j.transproceed.2010.05.112_bib9","first-page":"973","article-title":"Basal lamina of alveolar epithelium and capillaries: quantitative changes with aging and diabetes mellitus","volume":"120","author":"Vracko","year":"1979","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.transproceed.2010.05.112_bib10","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1164\/ajrccm\/137.1.162","article-title":"Experimental diabetes in the lung","volume":"37","author":"Ofulue","year":"1988","journal-title":"Am Rev Respir Dis"},{"key":"10.1016\/j.transproceed.2010.05.112_bib11","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1016\/S0041-1345(97)01291-8","article-title":"Pancreas transplantation versus islet transplantation versus insulin therapy in the prevention of nephropathy in alloxan-induced diabetic rats","volume":"30","author":"Spadella","year":"1998","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.05.112_bib12","doi-asserted-by":"crossref","first-page":"3468","DOI":"10.1016\/j.transproceed.2005.09.051","article-title":"Long-term effects of insulin therapy, islet transplantation, and pancreas transplantation in the prevention of glomerular changes in kidneys of alloxan-induced diabetic rats","volume":"37","author":"Spadella","year":"2005","journal-title":"Transpl Proc"},{"key":"10.1016\/j.transproceed.2010.05.112_bib13","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1016\/j.transproceed.2008.01.049","article-title":"Temporal relationship between successful pancreas transplantation and control of ocular complications in alloxan-induced diabetic rats","volume":"40","author":"Spadella","year":"2008","journal-title":"Transp Proc"},{"key":"10.1016\/j.transproceed.2010.05.112_bib14","doi-asserted-by":"crossref","first-page":"421","DOI":"10.1097\/00007890-197204000-00010","article-title":"Pancreaticoduodenal transplantation in the rat","volume":"13","author":"Lee","year":"1972","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2010.05.112_bib15","first-page":"158","article-title":"Microsurgical pancreatoduodenal transplantation in rats","volume":"33","author":"Spadella","year":"1996","journal-title":"Arq Gastroenterol (S\u00e3o Paulo)"},{"key":"10.1016\/j.transproceed.2010.05.112_bib16","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/0168-8227(94)90004-3","article-title":"Indications of reduced pulmonary function in type I (insulin-dependent) diabetes mellitus","volume":"25","author":"Innocenti","year":"1994","journal-title":"Diabetes Res Clin Pract"},{"key":"10.1016\/j.transproceed.2010.05.112_bib17","doi-asserted-by":"crossref","first-page":"527","DOI":"10.7326\/0003-4819-101-4-527","article-title":"Non-enzymatic glycosylation and the pathogenesis of diabetic complications","volume":"101","author":"Brownlee","year":"1984","journal-title":"Ann Intern Med"},{"key":"10.1016\/j.transproceed.2010.05.112_bib18","doi-asserted-by":"crossref","first-page":"1973","DOI":"10.1016\/j.freeradbiomed.2008.03.016","article-title":"Oxidative damage to extracellular matrix and its role in human pathologies","volume":"44","author":"Rees","year":"2008","journal-title":"Free Radic Biol Med"},{"key":"10.1016\/j.transproceed.2010.05.112_bib19","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1016\/0304-4165(79)90181-8","article-title":"Changes in lung lysyl oxidase activity in streptozotocin-diabetes and in starvation","volume":"585","author":"Maida","year":"1979","journal-title":"Biochem Biophys Acta"},{"key":"10.1016\/j.transproceed.2010.05.112_bib20","first-page":"35","article-title":"Changes in the lung in the diabetes mellitus","volume":"44","author":"Kodolova","year":"1982","journal-title":"Arkh Patol"},{"issue":"4 suppl 2","key":"10.1016\/j.transproceed.2010.05.112_bib21","doi-asserted-by":"crossref","first-page":"S86","DOI":"10.1681\/ASN.2005121343","article-title":"Renal protection in diabetes: role of glycemic control","volume":"17","author":"Fioretto","year":"2006","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.transproceed.2010.05.112_bib22","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1007\/s004230000124","article-title":"Pancreas organ transplantation","volume":"385","author":"Hopt","year":"2000","journal-title":"Langenbecks Arch Surg"},{"key":"10.1016\/j.transproceed.2010.05.112_bib23","doi-asserted-by":"crossref","first-page":"2977","DOI":"10.1007\/s00125-006-0463-5","article-title":"Pancreas transplant alone has beneficial effects on retinopathy in type 1 diabetic patients","volume":"49","author":"Giannarelli","year":"2006","journal-title":"Diabetologia"},{"key":"10.1016\/j.transproceed.2010.05.112_bib24","first-page":"437","article-title":"Effect of pancreas transplantation on diabetic somatic neuropathy","volume":"104","author":"Orloff","year":"1988","journal-title":"Surgery"}],"container-title":["Transplantation Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134510007773?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134510007773?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T21:26:46Z","timestamp":1758576406000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041134510007773"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,7]]},"references-count":24,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2010,7]]}},"alternative-id":["S0041134510007773"],"URL":"https:\/\/doi.org\/10.1016\/j.transproceed.2010.05.112","relation":{},"ISSN":["0041-1345"],"issn-type":[{"type":"print","value":"0041-1345"}],"subject":[],"published":{"date-parts":[[2010,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Pancreas Transplantation Prevents Morphologic and Ultrastructural Changes in Pulmonary Parenchyma of Alloxan-Induced Diabetic Rats","name":"articletitle","label":"Article Title"},{"value":"Transplantation Proceedings","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.transproceed.2010.05.112","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}