{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T00:42:29Z","timestamp":1758588149151,"version":"3.44.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"9","license":[{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,11,1]],"date-time":"2010-11-01T00:00:00Z","timestamp":1288569600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transplantation Proceedings"],"published-print":{"date-parts":[[2010,11]]},"DOI":"10.1016\/j.transproceed.2010.06.036","type":"journal-article","created":{"date-parts":[[2010,11,20]],"date-time":"2010-11-20T04:24:13Z","timestamp":1290227053000},"page":"3679-3687","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Antithymocyte Globulin Induction Therapy in Heart Transplantation: Prospective Randomized Study of High vs Standard Dosage"],"prefix":"10.1016","volume":"42","author":[{"given":"G.","family":"Faggian","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Forni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.D.","family":"Milano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.","family":"Chiominto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"B.H.","family":"Walpoth","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"T.","family":"Scarabelli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Mazzucco","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.transproceed.2010.06.036_bib1","doi-asserted-by":"crossref","first-page":"S31","DOI":"10.1097\/00005082-200509001-00005","article-title":"Outcomes and complications after heart transplantation: a review","volume":"20","author":"Hoffman","year":"2005","journal-title":"J Cardiovasc Nurs"},{"key":"10.1016\/j.transproceed.2010.06.036_bib2","doi-asserted-by":"crossref","first-page":"945","DOI":"10.1016\/j.healun.2005.05.018","article-title":"Registry of the International Society for Heart and Lung Transplantation: Twenty-second Official Adult Heart Transplant Report\u20142005","volume":"24","author":"Taylor","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib3","doi-asserted-by":"crossref","first-page":"331S","DOI":"10.1016\/j.transproceed.2004.01.024","article-title":"Use of cyclosporine in thoracic transplantation","volume":"36","author":"Zuckermann","year":"2004","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.06.036_bib4","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1097\/01.TP.0000120865.96360.DF","article-title":"Efficacy and safety of tacrolimus compared with cyclosporine microemulsion in primary simultaneous pancreas-kidney transplantation: 1-year results of a large multicenter trial","volume":"77","author":"Bechstein","year":"2004","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2010.06.036_bib5","doi-asserted-by":"crossref","first-page":"2684","DOI":"10.1016\/j.transproceed.2005.06.080","article-title":"Role of immunosuppressive regimen on the incidence and characteristics of cytomegalovirus infection in heart transplantation: a single-center experience with preemptive therapy","volume":"37","author":"De Santo","year":"2005","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.06.036_bib6","doi-asserted-by":"crossref","first-page":"1029","DOI":"10.1097\/01.TP.0000116442.81259.60","article-title":"Long-term toxicity of antithymocyte globulin induction may vary with choice of agent: a single-center retrospective study","volume":"77","author":"Ducloux","year":"2004","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2010.06.036_bib7","doi-asserted-by":"crossref","first-page":"2755","DOI":"10.1016\/j.transproceed.2005.05.003","article-title":"Immunosuppression with antithymocyte globulin in renal transplantation: better long-term graft survival","volume":"37","author":"Martins","year":"2005","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.06.036_bib8","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1016\/j.transproceed.2003.12.017","article-title":"Immunosuppression following intestinal transplantation","volume":"36","author":"Mueller","year":"2004","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.06.036_bib9","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1111\/j.1432-2277.2002.tb00171.x","article-title":"A prospective randomized controlled study on the efficacy and tolerance of two antilymphocytic globulins in the prevention of rejection in first-heart transplant recipients","volume":"15","author":"Schnetzler","year":"2002","journal-title":"Transpl Int"},{"key":"10.1016\/j.transproceed.2010.06.036_bib10","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1016\/S0041-1345(01)01980-7","article-title":"Induction therapy with bolus ATG increases cyclosporine sensitivity in renal transplant recipients","volume":"33","author":"Varghese","year":"2001","journal-title":"Transplant Proc"},{"issue":"suppl 1","key":"10.1016\/j.transproceed.2010.06.036_bib11","doi-asserted-by":"crossref","first-page":"S75","DOI":"10.1111\/tri.1992.5.s1.75","article-title":"Effect of ATG prophylaxis in sensitized and non-sensitized kidney graft recipients","volume":"5","author":"Kaden","year":"1992","journal-title":"Transpl Int"},{"key":"10.1016\/j.transproceed.2010.06.036_bib12","first-page":"4","article-title":"Eleven years intraoperative ATG bolus: a list of successes","volume":"7","author":"Kaden","year":"2002","journal-title":"Ann Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib13","doi-asserted-by":"crossref","first-page":"1673","DOI":"10.1093\/ndt\/15.10.1673","article-title":"Prevention of acute rejection with antithymocyte globulin, avoiding corticosteroids, and delaying cyclosporin after renal transplantation","volume":"15","author":"Cantarovich","year":"2000","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib14","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1097\/01.TP.0000130179.18176.3D","article-title":"Antithymocyte globulin induction allows a prolonged delay in the initiation of cyclosporine in heart transplant patients with postoperative renal dysfunction","volume":"78","author":"Cantarovich","year":"2004","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2010.06.036_bib15","doi-asserted-by":"crossref","first-page":"296","DOI":"10.1016\/j.healun.2003.12.014","article-title":"Induction therapy after cardiac transplantation: a comparison of anti-thymocyte globulin and daclizumab in the prevention of acute rejection","volume":"24","author":"Carlsen","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib16","doi-asserted-by":"crossref","first-page":"1297","DOI":"10.1016\/j.healun.2004.09.010","article-title":"A multicenter, prospective, randomized, double-blind trial of basiliximab in heart transplantation","volume":"24","author":"Mehra","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib17","doi-asserted-by":"crossref","first-page":"9S","DOI":"10.1016\/S0041-1345(00)00812-5","article-title":"Nephrotoxicity-free, mycophenolate mofetil-based induction\/maintenance immunosuppression in elderly recipients of renal allografts from elderly cadaveric donors","volume":"32","author":"Theodorakis","year":"2000","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.06.036_bib18","first-page":"587","article-title":"A working formulation for the standardization of nomenclature in the diagnosis of heart and lung rejection","volume":"9","author":"Billingham","year":"1990","journal-title":"J Heart Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib19","first-page":"744","article-title":"Heart transplant coronary artery disease detected by coronary angiography: a multi-institutional study of preoperative donor and recipient risk factors","volume":"17","author":"Costanzo","year":"1998","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib20","doi-asserted-by":"crossref","first-page":"511","DOI":"10.1016\/S1053-2498(01)00244-3","article-title":"Tacrolimus versus cyclosporine after lung transplantation: a prospective, open, randomized two-center trial comparing two different immunosuppressive protocols","volume":"20","author":"Treede","year":"2001","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib21","doi-asserted-by":"crossref","first-page":"631","DOI":"10.1016\/j.transproceed.2004.02.053","article-title":"Midterm results of a prospective randomized comparison of two different rabbit-antithymocyte globulin induction therapies after heart transplantation","volume":"36","author":"De Santo","year":"2004","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.06.036_bib22","doi-asserted-by":"crossref","first-page":"239","DOI":"10.3109\/00365549409011791","article-title":"Copenhagen Heart Transplant Group: Cytomegalovirus infection rate among heart transplant patients in relation to anti-thymocyte immunoglobulin induction therapy","volume":"26","author":"Krogsgaard","year":"1994","journal-title":"Scand J Infect Dis"},{"key":"10.1016\/j.transproceed.2010.06.036_bib23","doi-asserted-by":"crossref","first-page":"1890","DOI":"10.1097\/00007890-200005150-00026","article-title":"Improved long-term results with thymoglobuline induction therapy after cardiac transplantation: a comparison of two different rabbit-antithymocyte globulines","volume":"69","author":"Zuckermann","year":"2000","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2010.06.036_bib24","first-page":"214","article-title":"Effects of prophylactic rabbit antithymocyte globulin in cardiac allograft recipients treated with cyclosporine","volume":"6","author":"Kawaguchi","year":"1987","journal-title":"J Heart Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib25","first-page":"1","article-title":"Monoclonal versus polyclonal antibody therapy for prophylaxis against rejection after heart transplantation","volume":"9","author":"Kormos","year":"1990","journal-title":"J Heart Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib26","doi-asserted-by":"crossref","first-page":"587","DOI":"10.1016\/j.jacc.2008.05.020","article-title":"The changing face of heart transplantation","volume":"52","author":"Hunt","year":"2008","journal-title":"J Am Coll Cardiol"},{"key":"10.1016\/j.transproceed.2010.06.036_bib27","doi-asserted-by":"crossref","first-page":"1031","DOI":"10.1016\/j.healun.2009.08.004","article-title":"Registry of the International Society for Heart and Lung Transplantation: Twenty-sixth Official Adult Lung and Heart-Lung Transplantation Report\u20142009","volume":"28","author":"Christic","year":"2009","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib28","doi-asserted-by":"crossref","first-page":"2579","DOI":"10.1016\/j.transproceed.2004.09.049","article-title":"Impact of small variations of ischemia time after polyclonal antithymocyte globulins in a nonhuman primate model of ischemia-reperfusion injury","volume":"36","author":"Beiras-Fernandez","year":"2004","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.06.036_bib29","doi-asserted-by":"crossref","first-page":"1944","DOI":"10.1016\/j.transproceed.2005.04.008","article-title":"Influence of polyclonal ATGs on expression of adhesion molecules: an experimental study","volume":"37","author":"Beiras-Fernandez","year":"2005","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.06.036_bib30","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1111\/j.1432-2277.2004.tb00469.x","article-title":"Polyclonal anti-thymocyte globulins influence apoptosis in reperfused tissues after ischaemia in a non-human primate model","volume":"17","author":"Beiras-Fernandez","year":"2004","journal-title":"Transpl Int"},{"key":"10.1016\/j.transproceed.2010.06.036_bib31","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1097\/01.TP.0000150210.77543.1B","article-title":"Antithymocyte globulin induces ex vivo and in vivo depletion of myeloid and plasmacytoid dendritic cells","volume":"79","author":"Fang","year":"2005","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2010.06.036_bib32","doi-asserted-by":"crossref","first-page":"3361","DOI":"10.1016\/S0041-1345(99)00826-X","article-title":"Preoperative ATG bolus treatment increases CsA sensitivity of peripheral blood lymphocytes (PBLS) in renal transplant patients","volume":"31","author":"Abudher","year":"1999","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.06.036_bib33","doi-asserted-by":"crossref","first-page":"1582","DOI":"10.1097\/01.ASN.0000126194.77004.9B","article-title":"Malignancy in renal transplantation","volume":"15","author":"Morath","year":"2004","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.transproceed.2010.06.036_bib34","doi-asserted-by":"crossref","first-page":"830","DOI":"10.1097\/00007890-199503270-00006","article-title":"A randomized prospective trial of prophylactic immunosuppression with ATG-Fresenius versus OKT3 after renal transplantation","volume":"59","author":"Bock","year":"1995","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2010.06.036_bib35","doi-asserted-by":"crossref","first-page":"928","DOI":"10.1111\/j.1600-6143.2004.00451.x","article-title":"Cytomegalovirus prophylaxis and graft outcome in solid organ transplantation: a collaborative transplant study report","volume":"4","author":"Opelz","year":"2004","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib36","first-page":"3177","article-title":"The paradox of ATG monitoring in renal transplantation","volume":"26","author":"Shenton","year":"1994","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.06.036_bib37","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1046\/j.1600-6143.2003.00325.x","article-title":"Lymphomas after solid organ transplantation: a collaborative transplant study report","volume":"4","author":"Opelz","year":"2004","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2010.06.036_bib38","doi-asserted-by":"crossref","first-page":"1723","DOI":"10.1056\/NEJM199012203232502","article-title":"Increased incidence of lymphoproliferative disorder after immunosuppression with the monoclonal antibody OKT3 in cardiac-transplant recipients","volume":"323","author":"Swinnen","year":"1990","journal-title":"N Engl J Med"}],"container-title":["Transplantation Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134510013199?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134510013199?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T21:27:34Z","timestamp":1758576454000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041134510013199"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,11]]},"references-count":38,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2010,11]]}},"alternative-id":["S0041134510013199"],"URL":"https:\/\/doi.org\/10.1016\/j.transproceed.2010.06.036","relation":{},"ISSN":["0041-1345"],"issn-type":[{"type":"print","value":"0041-1345"}],"subject":[],"published":{"date-parts":[[2010,11]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Antithymocyte Globulin Induction Therapy in Heart Transplantation: Prospective Randomized Study of High vs Standard Dosage","name":"articletitle","label":"Article Title"},{"value":"Transplantation Proceedings","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.transproceed.2010.06.036","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}