{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T05:49:28Z","timestamp":1761630568892,"version":"3.38.0"},"reference-count":50,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2010,12,1]],"date-time":"2010-12-01T00:00:00Z","timestamp":1291161600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Transplantation Proceedings"],"published-print":{"date-parts":[[2010,12]]},"DOI":"10.1016\/j.transproceed.2010.10.013","type":"journal-article","created":{"date-parts":[[2010,12,18]],"date-time":"2010-12-18T09:14:57Z","timestamp":1292663697000},"page":"4573-4577","source":"Crossref","is-referenced-by-count":8,"title":["Results of a Two-Center Study Comparing Hepatic Fibrosis Progression in HCV-positive Liver Transplant Patients Receiving Cyclosporine or Tacrolimus"],"prefix":"10.1016","volume":"42","author":[{"given":"L.J.W.","family":"van der Laan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Hudson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S.","family":"McPherson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.E.","family":"Zondervan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R.C.","family":"Thomas","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.","family":"Kwekkeboom","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.S.","family":"Lindsay","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.D.","family":"Burt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G.","family":"Kazemier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.W.","family":"Tilanus","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.F.","family":"Bassendine","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.J.","family":"Metselaar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.transproceed.2010.10.013_bib1","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/S0168-8278(00)80231-7","article-title":"HCV-related fibrosis progression following liver transplantation: increase in recent years","volume":"32","author":"Berenguer","year":"2000","journal-title":"J Hepatol"},{"key":"10.1016\/j.transproceed.2010.10.013_bib2","doi-asserted-by":"crossref","first-page":"994","DOI":"10.1016\/0016-5085(94)90759-5","article-title":"Quantitation of hepatitis C virus RNA in liver transplant recipients","volume":"106","author":"Chazouilleres","year":"1994","journal-title":"Gastroenterol"},{"key":"10.1016\/j.transproceed.2010.10.013_bib3","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1002\/hep.510290122","article-title":"High incidence of allograft cirrhosis in hepatitis C virus genotype 1b infection following transplantation: relationship with rejection episodes","volume":"29","author":"Prieto","year":"1999","journal-title":"Hepatology"},{"key":"10.1016\/j.transproceed.2010.10.013_bib4","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1016\/S0016-5085(99)70454-3","article-title":"European Concerted Action on Viral Hepatitis (EUROHEP) Group: European collaborative study on factors influencing outcome after liver transplantation for hepatitis C","volume":"117","author":"Feray","year":"1999","journal-title":"Gastroenterology"},{"key":"10.1016\/j.transproceed.2010.10.013_bib5","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/00007890-200201150-00010","article-title":"Impact of the recurrence of hepatitis C virus infection after liver transplantation on the long-term viability of the graft","volume":"73","author":"S\u00e1nchez-Fueyo","year":"2002","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2010.10.013_bib6","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1053\/gast.2002.32418","article-title":"The association between hepatitis C infection and survival after orthotopic liver transplantation","volume":"122","author":"Forman","year":"2002","journal-title":"Gastroenterology"},{"key":"10.1016\/j.transproceed.2010.10.013_bib7","doi-asserted-by":"crossref","first-page":"823","DOI":"10.1002\/hep.510280333","article-title":"Predictors of patient and graft survival following liver transplantation for hepatitis C","volume":"28","author":"Charlton","year":"1998","journal-title":"Hepatology"},{"key":"10.1016\/j.transproceed.2010.10.013_bib8","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1097\/01.tp.0000267916.36343.ca","article-title":"Predictors of graft and patient survival in hepatitis C virus (HCV) recipients: model to predict HCV cirrhosis after liver transplantation","volume":"84","author":"Iacob","year":"2007","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2010.10.013_bib9","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1053\/jhep.2002.33993","article-title":"Contribution of donor age to the recent decrease in patient survival among HCV-infected liver transplantation recipients","volume":"36","author":"Berenguer","year":"2002","journal-title":"Hepatology"},{"key":"10.1016\/j.transproceed.2010.10.013_bib10","doi-asserted-by":"crossref","first-page":"1922","DOI":"10.1111\/j.1600-6143.2006.01408.x","article-title":"The impact of diabetes mellitus on fibrosis progression in patients transplanted for hepatitis C","volume":"6","author":"Foxton","year":"2006","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2010.10.013_bib11","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1097\/01.tp.0000270313.31328.63","article-title":"Older donor livers show early severe histological activity, fibrosis, and graft failure after liver transplantation for hepatitis C","volume":"84","author":"Rayhill","year":"2007","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2010.10.013_bib12","doi-asserted-by":"crossref","first-page":"612","DOI":"10.1111\/j.1478-3231.2007.01459.x","article-title":"Viral load 1 week after liver transplantation, donor age and rejections correlate with the outcome of recurrent hepatitis C","volume":"27","author":"Ciccorossi","year":"2007","journal-title":"Liver Int"},{"key":"10.1016\/j.transproceed.2010.10.013_bib13","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1136\/gut.51.2.248","article-title":"Advancing donor liver age and rapid fibrosis progression following transplantation for hepatitis C","volume":"51","author":"Wali","year":"2002","journal-title":"Gut"},{"issue":"suppl 1","key":"10.1016\/j.transproceed.2010.10.013_bib14","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1365-2893.2007.00920.x","article-title":"Risk factors for hepatitis C recurrence after liver transplantation","volume":"14","author":"Roche","year":"2007","journal-title":"J Viral Hepat"},{"key":"10.1016\/j.transproceed.2010.10.013_bib15","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1053\/jhep.2003.50278","article-title":"A model to predict severe HCV-related disease following liver transplantation","volume":"38","author":"Berenguer","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.transproceed.2010.10.013_bib16","first-page":"847","article-title":"The protective effect of cyclosporine against cirrhotic alteration of the liver","volume":"110","author":"Lie","year":"1991","journal-title":"Surgery"},{"key":"10.1016\/j.transproceed.2010.10.013_bib17","doi-asserted-by":"crossref","first-page":"2964","DOI":"10.1016\/j.transproceed.2006.08.131","article-title":"Long-term outcomes in liver transplant patients with hepatic C infection receiving tacrolimus or cyclosporine","volume":"38","author":"Villamil","year":"2006","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2010.10.013_bib18","doi-asserted-by":"crossref","first-page":"284","DOI":"10.1001\/archsurg.1996.01430150062013","article-title":"Hepatitis C viral infection in liver transplantation","volume":"131","author":"Johnson","year":"1996","journal-title":"Arch Surg"},{"key":"10.1016\/j.transproceed.2010.10.013_bib19","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1002\/lt.21000","article-title":"Factors influencing the progression of fibrosis in patients with recurrent hepatitis C after liver transplantation under antiviral therapy: a retrospective analysis of 939 liver biopsies in a single center","volume":"13","author":"Walter","year":"2007","journal-title":"Liver Transpl"},{"key":"10.1016\/j.transproceed.2010.10.013_bib20","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1002\/lt.20655","article-title":"Effect of calcineurin inhibitors on survival and histologic disease severity in HCV-infected liver transplant recipients","volume":"12","author":"Berenguer","year":"2006","journal-title":"Liver Transpl"},{"key":"10.1016\/j.transproceed.2010.10.013_bib21","doi-asserted-by":"crossref","first-page":"697","DOI":"10.3748\/wjg.v12.i5.697","article-title":"Cyclosporine versus tacrolimus in patients with HCV infection after liver transplantation: effects on virus replication and recurrent hepatitis","volume":"12","author":"Hilgard","year":"2006","journal-title":"World J Gastroenterol"},{"key":"10.1016\/j.transproceed.2010.10.013_bib22","doi-asserted-by":"crossref","first-page":"1056","DOI":"10.1053\/jlts.2001.27803","article-title":"Histological recurrence and progression of hepatitis C after orthotopic liver transplantation: influence of immunosuppressive regimens","volume":"7","author":"Hunt","year":"2001","journal-title":"Liver Transpl"},{"key":"10.1016\/j.transproceed.2010.10.013_bib23","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1023\/A:1013759230800","article-title":"Outcome of orthotopic liver transplantation in patients with hepatitis C","volume":"47","author":"Paik","year":"2002","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.transproceed.2010.10.013_bib24","doi-asserted-by":"crossref","first-page":"1258","DOI":"10.1002\/lt.20222","article-title":"Impact of tacrolimus versus cyclosporine in hepatitis C virus\u2013infected liver transplant recipients on recurrent hepatitis: a prospective, randomized trial","volume":"10","author":"Martin","year":"2004","journal-title":"Liver Transplantation"},{"key":"10.1016\/j.transproceed.2010.10.013_bib25","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1016\/0168-8278(95)80226-6","article-title":"Histological grading and staging of chronic hepatitis","volume":"22","author":"Ishak","year":"1995","journal-title":"J Hepatol"},{"key":"10.1016\/j.transproceed.2010.10.013_bib26","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1002\/hep.510240201","article-title":"An algorithm for the grading of activity in chronic hepatitis C","volume":"24","author":"Bedossa","year":"1996","journal-title":"Hepatology"},{"key":"10.1016\/j.transproceed.2010.10.013_bib27","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1097\/01.TP.0000129095.51031.42","article-title":"Results of LIS2T, a multicenter, randomized study comparing cyclosporine microemulsion with C2 monitoring and tacrolimus with C0 monitoring in de novo liver transplantation","volume":"77","author":"Levy","year":"2004","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2010.10.013_bib28","doi-asserted-by":"crossref","first-page":"1464","DOI":"10.1002\/lt.20802","article-title":"12-month follow-up analysis of a multicenter, randomized, prospective trial in de novo liver transplant recipients (LIS2T) comparing cyclosporine microemulsion (C2 monitoring) and tacrolimus","volume":"12","author":"Levy","year":"2006","journal-title":"Liver Transpl"},{"key":"10.1016\/j.transproceed.2010.10.013_bib29","doi-asserted-by":"crossref","first-page":"51","DOI":"10.1002\/lt.20532","article-title":"Cyclosporine suppresses hepatitis C virus in vitro and increases the chance of a sustained virological response after liver transplantation","volume":"12","author":"Firpi","year":"2006","journal-title":"Liver Transplantation"},{"key":"10.1016\/j.transproceed.2010.10.013_bib30","doi-asserted-by":"crossref","first-page":"4510","DOI":"10.1128\/JVI.80.9.4510-4520.2006","article-title":"Diverse effects of cyclosporine on hepatitis C virus strain replication","volume":"80","author":"Ishii","year":"2006","journal-title":"J Virol"},{"key":"10.1016\/j.transproceed.2010.10.013_bib31","doi-asserted-by":"crossref","first-page":"1282","DOI":"10.1053\/jhep.2003.50449","article-title":"Cyclosporin A suppresses replication of hepatitis C virus genome in cultured hepatocytes","volume":"38","author":"Watashi","year":"2003","journal-title":"Hepatology"},{"key":"10.1016\/j.transproceed.2010.10.013_bib32","doi-asserted-by":"crossref","first-page":"879","DOI":"10.1016\/j.bbrc.2006.03.059","article-title":"Evaluation of the anti\u2013hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811","volume":"343","author":"Goto","year":"2006","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.transproceed.2010.10.013_bib33","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1111\/j.1348-0421.2007.tb03883.x","article-title":"In vitro infection of immortalized primary hepatocytes by HCV genotype 4a and inhibition of virus replication by cyclosporin","volume":"51","author":"El-Farrash","year":"2007","journal-title":"Microbiol Immunol"},{"key":"10.1016\/j.transproceed.2010.10.013_bib34","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1053\/j.gastro.2006.08.027","article-title":"Mycophenolic acid inhibits hepatitis C virus replication and acts in synergy with cyclosporin A and interferon-\u03b1","volume":"131","author":"Henry","year":"2006","journal-title":"Gastroenterology"},{"key":"10.1016\/j.transproceed.2010.10.013_bib35","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.bbrc.2003.11.080","article-title":"Specific inhibition of hepatitis C virus replication by cyclosporin A","volume":"313","author":"Nakagawa","year":"2004","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.transproceed.2010.10.013_bib36","doi-asserted-by":"crossref","first-page":"808","DOI":"10.1111\/j.1432-2277.2007.00508.x","article-title":"Does cyclosporine inhibit in vivo hepatitis virus replication?\u2014a pilot study","volume":"20","author":"Wawrzynowicz-Syczewska","year":"2007","journal-title":"Transpl Int"},{"issue":"suppl 8","key":"10.1016\/j.transproceed.2010.10.013_bib37","first-page":"410","article-title":"The impact of calcineurin inhibitors (CNIs) on recurrent hepatitis C infection","volume":"3","author":"Levy","year":"2004","journal-title":"Am J Transplant"},{"issue":"11 suppl 2","key":"10.1016\/j.transproceed.2010.10.013_bib38","doi-asserted-by":"crossref","first-page":"S57","DOI":"10.1002\/lt.20597","article-title":"Recurrence of hepatitis C infection: where are we now?","volume":"11","author":"Charlton","year":"2005","journal-title":"Liver Transpl"},{"key":"10.1016\/j.transproceed.2010.10.013_bib39","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1136\/gut.45.3.427","article-title":"Longitudinal variation in hepatitis C virus (HCV) viraemia and early course of HCV infection after liver transplantation for HCV cirrhosis: the role of different immunosuppressive regimens","volume":"45","author":"Papatheodoridis","year":"1999","journal-title":"Gut"},{"issue":"suppl 2","key":"10.1016\/j.transproceed.2010.10.013_bib40","first-page":"Abst 14","article-title":"Choice of CNI as well as genotype influence response to antiviral therapy in liver transplant recipients treated for recurrent HCV","volume":"7","author":"Lilly","year":"2007","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2010.10.013_bib41","doi-asserted-by":"crossref","first-page":"292","DOI":"10.1002\/lt.21358","article-title":"Differential effects of calcineurin inhibitors, tacrolimus and cyclosporin A, on interferon-induced antiviral protein in human hepatocyte cells","volume":"14","author":"Hirano","year":"2008","journal-title":"Liver Transpl"},{"key":"10.1016\/j.transproceed.2010.10.013_bib42","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1002\/lt.21363","article-title":"Interfering with interferon: re-igniting the debate on calcineurin inhibitor choice and antiviral therapy for hepatitis C virus recurrence","volume":"14","author":"Watashi","year":"2008","journal-title":"Liver Transpl"},{"key":"10.1016\/j.transproceed.2010.10.013_bib43","doi-asserted-by":"crossref","first-page":"520","DOI":"10.1002\/lt.22032","article-title":"Calcineurin inhibitor tacrolimus does not interfere with the suppression of hepatitis C virus infection by interferon-alpha","volume":"16","author":"Pan","year":"2010","journal-title":"Liver Transpl"},{"key":"10.1016\/j.transproceed.2010.10.013_bib44","doi-asserted-by":"crossref","first-page":"310","DOI":"10.1002\/hep.510260209","article-title":"Hepatic stellate cell immunodetection and cirrhotic evolution of viral hepatitis in liver allografts","volume":"26","author":"Guido","year":"1997","journal-title":"Hepatology"},{"key":"10.1016\/j.transproceed.2010.10.013_bib45","doi-asserted-by":"crossref","first-page":"1017","DOI":"10.1002\/lt.21178","article-title":"Hepatic stellate cell activation in liver transplant patients with hepatitis C recurrence and in non-transplanted patients with chronic hepatitis C","volume":"13","author":"Cisneros","year":"2007","journal-title":"Liver Transpl"},{"key":"10.1016\/j.transproceed.2010.10.013_bib46","doi-asserted-by":"crossref","first-page":"1235","DOI":"10.1002\/lt.20432","article-title":"Early hepatic stellate cell activation is associated with advanced fibrosis after liver transplantation in recipients with hepatitis C","volume":"11","author":"Russo","year":"2005","journal-title":"Liver Transpl"},{"key":"10.1016\/j.transproceed.2010.10.013_bib47","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.dld.2004.11.009","article-title":"Alpha-SMA expression in hepatic stellate cells and quantitative analysis of hepatic fibrosis in cirrhosis and in recurrent chronic hepatitis after liver transplantation","volume":"37","author":"Carpino","year":"2005","journal-title":"Dig Liver Dis"},{"key":"10.1016\/j.transproceed.2010.10.013_bib48","doi-asserted-by":"crossref","first-page":"1161","DOI":"10.1002\/hep.1840210440","article-title":"Cyclosporin A and FK-506 in inhibition of rat Ito cell activation in vitro","volume":"21","author":"Ikeda","year":"1995","journal-title":"Hepatology"},{"key":"10.1016\/j.transproceed.2010.10.013_bib49","doi-asserted-by":"crossref","first-page":"4598","DOI":"10.1016\/j.transproceed.2005.10.104","article-title":"Cyclosporine suppresses cell growth and collagen production in hepatic stellate cells","volume":"37","author":"Nakamuta","year":"2005","journal-title":"Transpl Proc"},{"key":"10.1016\/j.transproceed.2010.10.013_bib50","doi-asserted-by":"crossref","first-page":"1273","DOI":"10.1111\/j.1478-3231.2007.01560.x","article-title":"NIM811, a nonimmunosuppressive cyclosporine analogue, suppresses collagen production and enhances collagenase activity in hepatic stellate cells","volume":"27","author":"Kohjima","year":"2007","journal-title":"Liver Int"}],"container-title":["Transplantation Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134510015782?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134510015782?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,2,28]],"date-time":"2025-02-28T23:16:50Z","timestamp":1740784610000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041134510015782"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,12]]},"references-count":50,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2010,12]]}},"alternative-id":["S0041134510015782"],"URL":"https:\/\/doi.org\/10.1016\/j.transproceed.2010.10.013","relation":{},"ISSN":["0041-1345"],"issn-type":[{"type":"print","value":"0041-1345"}],"subject":[],"published":{"date-parts":[[2010,12]]}}}