{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,20]],"date-time":"2026-09-20T19:01:24Z","timestamp":1789930884851,"version":"4.0.1"},"reference-count":17,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2017,5,1]],"date-time":"2017-05-01T00:00:00Z","timestamp":1493596800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","transplantation-proceedings.org","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transplantation Proceedings"],"published-print":{"date-parts":[[2017,5]]},"DOI":"10.1016\/j.transproceed.2017.02.037","type":"journal-article","created":{"date-parts":[[2017,4,27]],"date-time":"2017-04-27T07:15:38Z","timestamp":1493277338000},"page":"722-725","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":4,"title":["Overexpression of Hypoxia-Inducible Factor-1\u03b1 in Primary Graft Dysfunction Developing in an Orthotopic Lung Transplantation Rat\u00a0Model"],"prefix":"10.1016","volume":"49","author":[{"given":"F.","family":"Lunardi","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Zampieri","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Vadori","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.","family":"Bernardini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.E.","family":"Vuljan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"N.","family":"Nannini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Rea","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Cozzi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"F.","family":"Calabrese","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.transproceed.2017.02.037_bib1","doi-asserted-by":"publisher","first-page":"506","DOI":"10.1097\/MOT.0000000000000232","article-title":"Primary graft dysfunction: lessons learned about the first 72\u200ah after lung transplantation","volume":"20","author":"Porteous","year":"2015","journal-title":"Curr Opin Organ Transplant"},{"key":"10.1016\/j.transproceed.2017.02.037_bib2","doi-asserted-by":"publisher","first-page":"1009","DOI":"10.1136\/jcp.2003.015032","article-title":"The role of hypoxia inducible factor 1 (HIF-1) in hypoxia induced apoptosis","volume":"57","author":"Greijer","year":"2004","journal-title":"J\u00a0Clin Pathol"},{"key":"10.1016\/j.transproceed.2017.02.037_bib3","doi-asserted-by":"publisher","first-page":"10892","DOI":"10.1074\/jbc.M800102200","article-title":"Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia","volume":"283","author":"Zhang","year":"2008","journal-title":"J\u00a0Biol Chem"},{"key":"10.1016\/j.transproceed.2017.02.037_bib4","doi-asserted-by":"publisher","first-page":"537","DOI":"10.1056\/NEJMra1011165","article-title":"Oxygen sensing, homeostasis, and disease","volume":"365","author":"Semenza","year":"2011","journal-title":"N\u00a0Engl J Med"},{"key":"10.1016\/j.transproceed.2017.02.037_bib5","doi-asserted-by":"publisher","first-page":"2012","DOI":"10.1111\/j.1600-6143.2007.01875.x","article-title":"Donor myocardial HIF-1alpha is an independent predictor of cardiac allograft dysfunction: a 7-year prospective, exploratory study","volume":"7","author":"Aharinejad","year":"2007","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2017.02.037_bib6","doi-asserted-by":"publisher","first-page":"1481","DOI":"10.1111\/ajt.12737","article-title":"The role of hypoxia-inducible factors in organ donation and transplantation: the current perspective and future opportunities","volume":"14","author":"Akhtar","year":"2014","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2017.02.037_bib7","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1681\/ASN.2006070792","article-title":"Immunohistochemical detection of hypoxia-inducible factor-1alpha in human renal allograft biopsies","volume":"18","author":"Rosenberger","year":"2007","journal-title":"J\u00a0Am Soc Nephrol"},{"key":"10.1016\/j.transproceed.2017.02.037_bib8","doi-asserted-by":"publisher","first-page":"659","DOI":"10.1093\/ndt\/gfs377","article-title":"Expression of hypoxia-inducible factor-1\u03b1 (HIF-1\u03b1) in infiltrating inflammatory cells is associated with chronic allograft dysfunction and predicts long-term graft survival","volume":"28","author":"Yu","year":"2013","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.transproceed.2017.02.037_bib9","doi-asserted-by":"publisher","first-page":"127","DOI":"10.1016\/j.trre.2015.05.001","article-title":"Systematic review with meta-analysis: HIF-1\u03b1 attenuates liver ischemia-reperfusion injury","volume":"29","author":"Guo","year":"2015","journal-title":"Transplant Rev (Orlando)"},{"key":"10.1016\/j.transproceed.2017.02.037_bib10","doi-asserted-by":"publisher","first-page":"266","DOI":"10.2741\/E614","article-title":"Experimental models of lung transplantation","volume":"5","author":"Bribriesco","year":"2013","journal-title":"Front Biosci"},{"key":"10.1016\/j.transproceed.2017.02.037_bib11","doi-asserted-by":"publisher","first-page":"486","DOI":"10.1016\/j.jtcvs.2008.10.007","article-title":"A\u00a0mouse model of orthotopic, single-lung transplantation","volume":"137","author":"Jungraithmayr","year":"2009","journal-title":"J\u00a0Thorac Cardiovasc Surg"},{"key":"10.1016\/j.transproceed.2017.02.037_bib12","doi-asserted-by":"publisher","first-page":"133","DOI":"10.1161\/01.RES.0000197816.63513.27","article-title":"Hypoxia inducible factor-1 activation by prolyl 4-hydroxylase-2 gene silencing attenuates myocardial ischemia reperfusion injury","volume":"98","author":"Natarajan","year":"2006","journal-title":"Circ Res"},{"key":"10.1016\/j.transproceed.2017.02.037_bib13","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1097\/NNR.0000000000000132","article-title":"Hypoxia-inducible factor-1\u03b1 gene expression and apoptosis in ischemia-reperfusion injury: a rat model of early-stage pressure ulcer","volume":"65","author":"Wang","year":"2016","journal-title":"Nurs Res"},{"key":"10.1016\/j.transproceed.2017.02.037_bib14","doi-asserted-by":"publisher","first-page":"7","DOI":"10.1016\/j.expneurol.2008.10.016","article-title":"Prodeath or prosurvival: two facets of hypoxia-inducible factor-1 in perinatal brain injury","volume":"216","author":"Chen","year":"2009","journal-title":"Exp Neurol"},{"key":"10.1016\/j.transproceed.2017.02.037_bib15","doi-asserted-by":"publisher","first-page":"176","DOI":"10.1152\/physiol.00001.2004","article-title":"Hydroxylation of HIF-1: oxygen sensing at the molecular level","volume":"19","author":"Semenza","year":"2004","journal-title":"Physiology"},{"key":"10.1016\/j.transproceed.2017.02.037_bib16","doi-asserted-by":"publisher","first-page":"1151","DOI":"10.1096\/fj.01-0944rev","article-title":"Cellular adaptation to hypoxia: O2-sensing protein hydroxylases, hypoxia-inducible transcription factors, and O2-regulated gene expression","volume":"16","author":"Wenger","year":"2002","journal-title":"FASEB J"},{"key":"10.1016\/j.transproceed.2017.02.037_bib17","doi-asserted-by":"publisher","first-page":"889","DOI":"10.1016\/S0006-2952(02)01155-3","article-title":"Is HIF-1alpha a pro- or an anti-apoptotic protein?","volume":"64","author":"Piret","year":"2002","journal-title":"Biochem Pharmacol"}],"container-title":["Transplantation Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134517301720?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134517301720?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,2]],"date-time":"2018-09-02T05:27:29Z","timestamp":1535866049000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041134517301720"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,5]]},"references-count":17,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2017,5]]}},"alternative-id":["S0041134517301720"],"URL":"https:\/\/doi.org\/10.1016\/j.transproceed.2017.02.037","relation":{},"ISSN":["0041-1345"],"issn-type":[{"value":"0041-1345","type":"print"}],"subject":[],"published":{"date-parts":[[2017,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Overexpression of Hypoxia-Inducible Factor-1\u03b1 in Primary Graft Dysfunction Developing in an Orthotopic Lung Transplantation Rat\u00a0Model","name":"articletitle","label":"Article Title"},{"value":"Transplantation Proceedings","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.transproceed.2017.02.037","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}