{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T06:37:06Z","timestamp":1740119826366,"version":"3.37.3"},"reference-count":20,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100020205","name":"Health Commission of Jiangxi Province","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100020205","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004479","name":"Jiangxi Provincial Natural Science Foundation","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004479","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.fr","clinicalkey.jp","clinicalkey.com.au","clinicalkey.es","clinicalkey.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transplantation Proceedings"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.transproceed.2024.11.007","type":"journal-article","created":{"date-parts":[[2024,11,27]],"date-time":"2024-11-27T04:29:16Z","timestamp":1732681756000},"page":"2292-2297","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Diosgenin Mediated JAK\/STAT Signal Channel Improving SD Rat Renal Ischemia-Reperfusion"],"prefix":"10.1016","volume":"56","author":[{"given":"Jinran","family":"Yang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xinchang","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chengmei","family":"Long","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Youfu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hua","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tongchang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xuyang","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaomei","family":"Huang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"1","key":"10.1016\/j.transproceed.2024.11.007_bib0001","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1097\/MOT.0000000000000604","article-title":"Delayed graft function in kidney transplantation","volume":"24","author":"Bahl","year":"2019","journal-title":"Curr Opin Organ Tran"},{"key":"10.1016\/j.transproceed.2024.11.007_bib0002","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.ebiom.2018.01.025","article-title":"Ischemia-reperfusion injury reduces long term renal graft survival: mechanism and beyond","volume":"28","author":"Zhao","year":"2018","journal-title":"EBioMedicine"},{"key":"10.1016\/j.transproceed.2024.11.007_bib0003","doi-asserted-by":"crossref","DOI":"10.1155\/2022\/1035441","article-title":"Diosgenin: an updated pharmacological review and therapeutic perspectives","volume":"2022","author":"Semwal","year":"2022","journal-title":"Oxid Med Cell Longev"},{"key":"10.1016\/j.transproceed.2024.11.007_bib0004","doi-asserted-by":"crossref","DOI":"10.1016\/j.intimp.2020.106210","article-title":"The role of JAK\/STAT signaling pathway and its inhibitors in diseases","volume":"80","author":"Xin","year":"2020","journal-title":"Int Immunopharmacol"},{"issue":"3","key":"10.1016\/j.transproceed.2024.11.007_bib0005","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1080\/10408390600698197","article-title":"Saponins: properties, applications and processing","volume":"47","author":"G\u00fc\u00e7l\u00fc-Ust\u00fcnda\u011f","year":"2007","journal-title":"Crit Rev Food Sci Nutr"},{"issue":"5","key":"10.1016\/j.transproceed.2024.11.007_bib0006","doi-asserted-by":"crossref","first-page":"526","DOI":"10.1016\/0923-2494(92)80064-R","article-title":"Saponin","volume":"143","author":"Campbell","year":"1992","journal-title":"Res Immunol"},{"key":"10.1016\/j.transproceed.2024.11.007_bib0007","doi-asserted-by":"crossref","first-page":"246","DOI":"10.12659\/MSM.907745","article-title":"Diosgenin protects rats from myocardial inflammatory injury induced by ischemia-reperfusion","volume":"24","author":"Wang","year":"2018","journal-title":"Med Sci Monit"},{"key":"10.1016\/j.transproceed.2024.11.007_bib0008","doi-asserted-by":"crossref","first-page":"431","DOI":"10.1016\/j.phrs.2018.11.040","article-title":"Dioscin ameliorates intestinal ischemia\/reperfusion injury via adjusting miR-351-5p\/MAPK13-mediated inflammation and apoptosis","volume":"139","author":"Zheng","year":"2019","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.transproceed.2024.11.007_bib0009","doi-asserted-by":"crossref","first-page":"105575","DOI":"10.1016\/j.jsbmb.2019.105575","article-title":"The role of diosgenin in diabetes and diabetic complications","volume":"198","author":"Gan","year":"2020","journal-title":"J Steroid Biochem Mol Biol"},{"key":"10.1016\/j.transproceed.2024.11.007_bib0010","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2023.1226548","article-title":"Literature review on hepatoprotective effects of diosgenin: possible mechanisms of action","volume":"14","author":"Mohseni-Moghaddam","year":"2023","journal-title":"Front Pharmacol."},{"key":"10.1016\/j.transproceed.2024.11.007_bib0011","doi-asserted-by":"crossref","DOI":"10.1016\/j.gene.2023.147383","article-title":"Diosgenin reduces bone loss through the regulation of gut microbiota in ovariectomized rats","volume":"869","author":"Song","year":"2023","journal-title":"Gene."},{"issue":"4","key":"10.1016\/j.transproceed.2024.11.007_bib0012","doi-asserted-by":"crossref","first-page":"R373","DOI":"10.1186\/ar1199","article-title":"Diosgenin, a plant steroid, induces apoptosis in human rheumatoid arthritis synoviocytes with cyclooxygenase-2 overexpression","volume":"6","author":"Liagre","year":"2004","journal-title":"Arthritis Res Ther."},{"issue":"2","key":"10.1016\/j.transproceed.2024.11.007_bib0013","doi-asserted-by":"crossref","first-page":"238","DOI":"10.1080\/08923973.2022.2037632","article-title":"Dioscin promotes autophagy by regulating the AMPK-mTOR pathway in ulcerative colitis","volume":"44","author":"Li","year":"2022","journal-title":"Immunopharmacol Immunotoxicol"},{"issue":"4","key":"10.1016\/j.transproceed.2024.11.007_bib0014","doi-asserted-by":"crossref","first-page":"580","DOI":"10.1021\/np100578u","article-title":"Diosgenin, a plant-derived sapogenin, exhibits antiviral activity in vitro against hepatitis C virus","volume":"74","author":"Wang","year":"2011","journal-title":"J Nat Prod."},{"issue":"2","key":"10.1016\/j.transproceed.2024.11.007_bib0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.heliyon.2024.e24350","article-title":"Role of diosgenin extracted from Helicteres isora L in suppression of HIV-1 replication: An in vitro preclinical study","volume":"10","author":"Rakshit","year":"2024","journal-title":"Heliyon"},{"key":"10.1016\/j.transproceed.2024.11.007_bib0016","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.phrs.2015.08.025","article-title":"Corrigendum to \u2018Dioscin attenuates renal ischemia\/reperfusion injury by inhibiting the TLR4\/MyD88 signaling pathway via up-regulation of HSP70\u2019","volume":"100","author":"Qi","year":"2015","journal-title":"Pharmacol Res"},{"issue":"3","key":"10.1016\/j.transproceed.2024.11.007_bib0017","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a011205","article-title":"The JAK\/STAT pathway","volume":"4","author":"Harrison","year":"2012","journal-title":"Cold Spring Harb Perspect Biol"},{"issue":"1\u20132","key":"10.1016\/j.transproceed.2024.11.007_bib0018","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/S0161-5890(00)00018-3","article-title":"The Jak-STAT pathway","volume":"37","author":"Imada","year":"2000","journal-title":"Mol Immunol"},{"issue":"1","key":"10.1016\/j.transproceed.2024.11.007_bib0019","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.tem.2017.11.001","article-title":"JAK\/STAT \u2013 emerging players in metabolism","volume":"29","author":"Dodington","year":"2018","journal-title":"Trends Endocrinol Metabol: TEM"},{"issue":"1","key":"10.1016\/j.transproceed.2024.11.007_bib0020","doi-asserted-by":"crossref","first-page":"28","DOI":"10.1186\/s40659-020-00297-0","article-title":"Edaravone alleviates cell apoptosis and mitochondrial injury in ischemia-reperfusion-induced kidney injury via the JAK\/STAT pathway","volume":"53","author":"Zhao","year":"2020","journal-title":"Biol Res"}],"container-title":["Transplantation Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134524005517?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134524005517?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,15]],"date-time":"2024-12-15T08:40:44Z","timestamp":1734252044000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041134524005517"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":20,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S0041134524005517"],"URL":"https:\/\/doi.org\/10.1016\/j.transproceed.2024.11.007","relation":{},"ISSN":["0041-1345"],"issn-type":[{"type":"print","value":"0041-1345"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Diosgenin Mediated JAK\/STAT Signal Channel Improving SD Rat Renal Ischemia-Reperfusion","name":"articletitle","label":"Article Title"},{"value":"Transplantation Proceedings","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.transproceed.2024.11.007","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}