{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T08:59:50Z","timestamp":1780822790427,"version":"3.54.1"},"reference-count":101,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,12,1]],"date-time":"2025-12-01T00:00:00Z","timestamp":1764547200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,10,23]],"date-time":"2025-10-23T00:00:00Z","timestamp":1761177600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100002322","name":"Coordination for the improvement of Higher Education Personnel","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100002322","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transplantation Proceedings"],"published-print":{"date-parts":[[2025,12]]},"DOI":"10.1016\/j.transproceed.2025.10.028","type":"journal-article","created":{"date-parts":[[2025,11,17]],"date-time":"2025-11-17T21:59:42Z","timestamp":1763416782000},"page":"2028-2037","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Current Methodological Procedures in Rat Models After Circulatory Death"],"prefix":"10.1016","volume":"57","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-5249-4757","authenticated-orcid":false,"given":"Mayara Munhoz","family":"de Assis Ramos","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fernanda Yamamoto","family":"Ricardo-da-Silva","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larissa dos Santos","family":"Pedroso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Henri G.D.","family":"Leuvenink","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ana Cristina","family":"Breithaupt-Faloppa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luiz Felipe Pinho","family":"Moreira","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.transproceed.2025.10.028_bib0001","doi-asserted-by":"crossref","first-page":"1440","DOI":"10.1097\/TP.0000000000004480","article-title":"Expanding donor options for lung transplant: extended criteria, donation after circulatory death, ABO incompatibility, and evolution of ex vivo lung perfusion","volume":"107","author":"Noda","year":"2023","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0002","doi-asserted-by":"crossref","first-page":"2165","DOI":"10.1111\/ajt.14214","article-title":"Improving the outcomes of organs obtained from controlled donation after circulatory death donors using abdominal normothermic regional perfusion","volume":"17","author":"Mi\u00f1ambres","year":"2017","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0003","doi-asserted-by":"crossref","first-page":"6594","DOI":"10.21037\/jtd-2021-07","article-title":"Living-donor lobar lung transplantation","volume":"13","author":"Nakajima","year":"2021","journal-title":"J Thorac Dis"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0004","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1111\/tri.13506","article-title":"Donation after circulatory death today: an updated overview of the European landscape","volume":"33","author":"Lomero","year":"2020","journal-title":"Transpl Int"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0005","unstructured":"British Transplantation Society (BTS). UK Guidelines on transplantation from deceased donors after circulatory death,https:\/\/bts.org.uk\/transplantation-from-deceased-donors-after-circulatory-death\/; [accessed 12\/03\/2025]."},{"issue":"Suppl 1","key":"10.1016\/j.transproceed.2025.10.028_bib0006","article-title":"Donation after circulatory death","volume":"108","author":"Manara","year":"2012","journal-title":"Br J Anaesth"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0007","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.jcis.2020.09.030","article-title":"Design of a ratiometric fluorescence sensor based on metal organic frameworks and Ru(bpy)32+-doped silica composites for 17\u03b2-Estradiol detection","volume":"583","author":"Sha","year":"2021","journal-title":"J Colloid Interface Sci"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0008","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cryobiol.2020.04.009","article-title":"Current techniques and the future of lung preservation","volume":"94","author":"Lautner","year":"2020","journal-title":"Cryobiology"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0009","doi-asserted-by":"crossref","first-page":"10","DOI":"10.4103\/0976-9668.175017","article-title":"Challenges and advances in optimizing liver allografts from donation after circulatory death donors","volume":"7","author":"Sutherland","year":"2016","journal-title":"J Nat Sci Biol Med"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0010","doi-asserted-by":"crossref","first-page":"7","DOI":"10.5493\/wjem.v4.i2.7","article-title":"Animal models of ex vivo lung perfusion as a platform for transplantation research","volume":"4","author":"Nelson","year":"2014","journal-title":"World J Exp Med"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0011","doi-asserted-by":"crossref","first-page":"L61","DOI":"10.1152\/ajplung.00256.2019","article-title":"A method for translational rat ex vivo lung perfusion experimentation","volume":"319","author":"Ohsumi","year":"2020","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0012","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1016\/j.ejcts.2009.05.010","article-title":"The mode of death in the non-heart-beating donor has an impact on lung graft quality","volume":"36","author":"Van de Wauwer","year":"2009","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0013","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.jss.2015.02.029","article-title":"Impact of the cardiac arrest mode on cardiac death donor lungs","volume":"195","author":"Yamada","year":"2015","journal-title":"J Surg Res"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0014","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/0300-9572(95)00873-R","article-title":"The hemodynamic and arterial blood gas response to asphyxiation: a canine model of pulseless electrical activity","volume":"30","author":"DeBehnke","year":"1995","journal-title":"Resuscitation"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0015","doi-asserted-by":"crossref","first-page":"589","DOI":"10.1111\/j.1432-2277.2006.00318.x","article-title":"Normothermic ex vivo lung perfusion of non-heart-beating donor lungs in pigs: from pretransplant function analysis towards a 6-h machine preservation","volume":"19","author":"Erasmus","year":"2006","journal-title":"Transpl Int"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0016","doi-asserted-by":"crossref","first-page":"564","DOI":"10.3109\/01902148.2015.1123328","article-title":"Organotypic lung culture: a new model for studying ischemia and ex vivo perfusion in lung transplantation","volume":"41","author":"Baste","year":"2015","journal-title":"Exp Lung Res"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0017","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1007\/s11748-018-1038-3","article-title":"Long agonal period deteriorates cardiac death donor lung function in a rat EVLP model","volume":"67","author":"Hijiya","year":"2019","journal-title":"Gen Thorac Cardiovasc Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0018","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.healun.2018.08.006","article-title":"Influence of lung donor agonal and warm ischemic times on early mortality: analyses from the ISHLT DCD Lung Transplant Registry","volume":"38","author":"Levvey","year":"2019","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0019","doi-asserted-by":"crossref","first-page":"1546","DOI":"10.1016\/j.jtcvs.2020.04.181","article-title":"Impact of donor time to cardiac arrest in lung donation after circulatory death","volume":"161","author":"Qaqish","year":"2021","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0020","doi-asserted-by":"crossref","first-page":"e337","DOI":"10.1097\/TP.0000000000003793","article-title":"Antemortem heparin in organ donation after circulatory death determination: a systematic review of the literature","volume":"105","author":"Honarmand","year":"2021","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0021","unstructured":"Academy of Medical Royal Colleges. A Code of Practice for the diagnosis and confirmation of death: 2025 update. https:\/\/www.aomrc.org.uk\/wp-content\/uploads\/2025\/01\/Code_of_Practice_Diagnosis_of_Death_010125.pdf; [accessed 12\/03\/2025]."},{"key":"10.1016\/j.transproceed.2025.10.028_bib0022","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.ajt.2022.10.009","article-title":"American Society of Transplant Surgeons recommendations on best practices in donation after circulatory death organ procurement","volume":"23","author":"Croome","year":"2023","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0023","doi-asserted-by":"crossref","first-page":"E474","DOI":"10.1503\/cjs.023120","article-title":"Premortem anticoagulation timing and dose in donation after circulatory death: multicentre study of associations with graft function","volume":"65","author":"Kramer","year":"2022","journal-title":"Can J Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0024","doi-asserted-by":"crossref","first-page":"534","DOI":"10.1097\/SLA.0b013e318273bef1","article-title":"Ex vivo lung evaluation of prearrest heparinization in donation after cardiac death","volume":"257","author":"Sanchez","year":"2013","journal-title":"Ann Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0025","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1093\/ejcts\/ezs364","article-title":"Heparin does not improve graft function in uncontrolled non-heart-beating lung donation: an experimental study in pigs","volume":"43","author":"Wallinder","year":"2013","journal-title":"Eur J Cardiothorac Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0026","doi-asserted-by":"crossref","first-page":"300","DOI":"10.1053\/j.semtcvs.2004.09.012","article-title":"Lung preservation","volume":"16","author":"de Perrot","year":"2004","journal-title":"Semin Thorac Cardiovasc Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0027","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1097\/MOT.0000000000000234","article-title":"Update on ischemia-reperfusion injury in lung transplantation","volume":"20","author":"Chen","year":"2015","journal-title":"Curr Opin Organ Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0028","doi-asserted-by":"crossref","first-page":"556","DOI":"10.1016\/j.jtcvs.2023.05.027","article-title":"The effect of allograft ischemic time on outcomes following bilateral, single, and reoperative lung transplantation","volume":"167","author":"Casillan","year":"2024","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0029","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1016\/j.trim.2011.11.002","article-title":"Peculiar mechanisms of graft recovery through anti-inflammatory responses after rat lung transplantation from donation after cardiac death","volume":"26","author":"Yamamoto","year":"2012","journal-title":"Transpl Immunol"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0030","doi-asserted-by":"crossref","first-page":"3628","DOI":"10.1016\/j.transproceed.2011.09.075","article-title":"Activations of mitogen-activated protein kinases and regulation of their downstream molecules after rat lung transplantation from donors after cardiac death","volume":"43","author":"Yamamoto","year":"2011","journal-title":"Transplant Proc"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0031","doi-asserted-by":"crossref","first-page":"5532","DOI":"10.1096\/fj.201701255R","article-title":"Influence of ex vivo perfusion on the biomolecular profile of rat lungs","volume":"32","author":"Lonati","year":"2018","journal-title":"FASEB J"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0032","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1097\/TP.0000000000002140","article-title":"Effects of warm versus cold ischemic donor lung preservation on the underlying mechanisms of injuries during ischemia and reperfusion","volume":"102","author":"Iskender","year":"2018","journal-title":"Transplantation"},{"issue":"199","key":"10.1016\/j.transproceed.2025.10.028_bib0033","doi-asserted-by":"crossref","DOI":"10.3791\/65981","article-title":"Establishment of an ex vivo lung perfusion rat model for translational insights in lung transplantation","volume":"2023","author":"Oliveira","year":"2023","journal-title":"J Vis Exp"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0034","doi-asserted-by":"crossref","first-page":"131","DOI":"10.3109\/01902148.2016.1158887","article-title":"Role of inflammatory cells and adenosine in lung ischemia reoxygenation injury using a model of lung donation after cardiac death","volume":"42","author":"Smail","year":"2016","journal-title":"Exp Lung Res"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0035","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1097\/TP.0b013e3181c46a74","article-title":"Lung transplantation from nonheparinized category III non-heart-beating donors. A single-centre report","volume":"89","author":"Erasmus","year":"2010","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0036","article-title":"Donation after circulatory death and lung transplantation","volume":"48","author":"Dos Santos","year":"2022","journal-title":"J Bras Pneumol"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0037","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1016\/S1010-7940(00)00631-X","article-title":"Flush perfusion with low potassium dextran solution improves early graft function in clinical lung transplantation","volume":"19","author":"Str\u00fcber","year":"2001","journal-title":"Eur J Cardiothoracic Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0038","doi-asserted-by":"crossref","first-page":"1081","DOI":"10.1016\/j.healun.2004.07.004","article-title":"Experimental lung transplantation: impact of preservation solution and route of delivery","volume":"24","author":"Wittwer","year":"2005","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0039","doi-asserted-by":"crossref","first-page":"711","DOI":"10.1016\/0003-4975(93)90280-U","article-title":"Influence of temperature of flushing solution on lung preservation","volume":"55","author":"Wang","year":"1993","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0040","doi-asserted-by":"crossref","first-page":"5","DOI":"10.1159\/000129501","article-title":"Influence of the perfusate temperature on lung preservation: is there an optimum?","volume":"29","author":"Albes","year":"1997","journal-title":"Eur Surg Res"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0041","doi-asserted-by":"crossref","first-page":"e54","DOI":"10.1093\/ejcts\/ezt598","article-title":"Successful prolonged ex vivo lung perfusion for graft preservation in rats","volume":"45","author":"Noda","year":"2014","journal-title":"Eur J Cardiothorac Surg"},{"issue":"96","key":"10.1016\/j.transproceed.2025.10.028_bib0042","doi-asserted-by":"crossref","DOI":"10.3791\/52309-v","article-title":"Method of isolated ex vivo lung perfusion in a rat model: lessons learned from developing a rat EVLP program","author":"Nelson","year":"2015","journal-title":"J Vis Exp"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0043","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/j.healun.2019.09.009","article-title":"Reduced-flow ex vivo lung perfusion to rehabilitate lungs donated after circulatory death","volume":"39","author":"Beller","year":"2020","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0044","doi-asserted-by":"crossref","first-page":"1319","DOI":"10.1016\/j.healun.2008.09.003","article-title":"Technique for prolonged normothermic ex vivo lung perfusion","volume":"27","author":"Cypel","year":"2008","journal-title":"J Heart Lung Transplant"},{"issue":"5","key":"10.1016\/j.transproceed.2025.10.028_bib0045","doi-asserted-by":"crossref","first-page":"1208","DOI":"10.1016\/j.jtcvs.2012.07.056","article-title":"Ex vivo rehabilitation of non-heart-beating donor lungs in preclinical porcine model: delayed perfusion results in superior lung function","volume":"144","author":"Mulloy","year":"2012","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"9","key":"10.1016\/j.transproceed.2025.10.028_bib0046","doi-asserted-by":"crossref","first-page":"1347","DOI":"10.1016\/j.healun.2004.10.016","article-title":"Influence of donor characteristics on outcome after lung transplantation: a multicenter study","volume":"24","author":"Thabut","year":"2005","journal-title":"J Heart Lung Transplant"},{"issue":"10","key":"10.1016\/j.transproceed.2025.10.028_bib0047","doi-asserted-by":"crossref","first-page":"1047","DOI":"10.1016\/j.healun.2017.07.016","article-title":"The Registry of the International Society for Heart and Lung Transplantation: Thirty-fourth Adult Lung and Heart-Lung Transplantation Report-2017; Focus Theme: Allograft ischemic time","volume":"36","author":"Chambers","year":"2017","journal-title":"J Heart Lung Transplant"},{"issue":"10","key":"10.1016\/j.transproceed.2025.10.028_bib0048","doi-asserted-by":"crossref","first-page":"1070","DOI":"10.1016\/j.healun.2017.07.017","article-title":"International Society for Heart and Lung Transplantation. Registry of the International Society for Heart and Lung Transplantation: Twentieth Pediatric Lung and Heart-Lung Transplantation Report-2017; Focus Theme: Allograft ischemic time","volume":"36","author":"Goldfarb","year":"2017","journal-title":"J Heart Lung Transplant"},{"issue":"1","key":"10.1016\/j.transproceed.2025.10.028_bib0049","doi-asserted-by":"crossref","first-page":"24","DOI":"10.1097\/00007890-199301000-00006","article-title":"Attenuation of warm ischemic injury of rat lung by inflation with room air\u2013assessment of cellular components and the surfactant in the bronchoalveolar lavage fluid in relation to changes in cellular adenosine triphosphate","volume":"55","author":"Akashi","year":"1993","journal-title":"Transplantation"},{"issue":"3","key":"10.1016\/j.transproceed.2025.10.028_bib0050","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1055\/s-2004-817977","article-title":"Warm or cold ischemia in animal models of lung ischemia-reperfusion injury: is there a difference?","volume":"52","author":"Warnecke","year":"2004","journal-title":"Thorac Cardiovasc Surg"},{"issue":"8","key":"10.1016\/j.transproceed.2025.10.028_bib0051","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1097\/TP.0b013e31822d8778","article-title":"Hypothermic machine perfusion ameliorates ischemia-reperfusion injury in rat lungs from non-heart-beating donors","volume":"92","author":"Nakajima","year":"2011","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0052","doi-asserted-by":"crossref","first-page":"44","DOI":"10.6002\/ect.2011.0161","article-title":"Ischemic postconditioning reduces ischemic reperfusion injury of non-heart-beating donor grafts in a rat lung transplant","volume":"11","author":"Hu","year":"2013","journal-title":"Exp Clin Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0053","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.resp.2014.10.002","article-title":"The protective effect of hypercapnia on ischemia-reperfusion injury in lungs","volume":"205","author":"Mrazkova","year":"2015","journal-title":"Respir Physiol Neurobiol"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0054","doi-asserted-by":"crossref","first-page":"953","DOI":"10.33549\/physiolres.933273","article-title":"Influence of gender on ischemia-reperfusion injury in lungs in an animal model","volume":"65","author":"Mrazkova","year":"2016","journal-title":"Physiol Res"},{"issue":"23","key":"10.1016\/j.transproceed.2025.10.028_bib0055","doi-asserted-by":"crossref","first-page":"3959","DOI":"10.3390\/cancers16233959","article-title":"Machine perfusion as a strategy to decrease ischemia-reperfusion injury and lower cancer recurrence following liver transplantation","volume":"16","author":"Garcia","year":"2024","journal-title":"Cancers (Basel)"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0056","doi-asserted-by":"crossref","DOI":"10.3389\/fcvm.2023.1272945","article-title":"Pushing the boundaries of innovation: the potential of ex vivo organ perfusion from an interdisciplinary point of view","volume":"10","author":"Iske","year":"2023","journal-title":"Front Cardiovasc Med"},{"issue":"15","key":"10.1016\/j.transproceed.2025.10.028_bib0057","doi-asserted-by":"crossref","first-page":"1431","DOI":"10.1056\/NEJMoa1014597","article-title":"Normothermic ex vivo lung perfusion in clinical lung transplantation","volume":"364","author":"Cypel","year":"2011","journal-title":"N Engl J Med"},{"issue":"12","key":"10.1016\/j.transproceed.2025.10.028_bib0058","doi-asserted-by":"crossref","first-page":"1143","DOI":"10.1001\/jamasurg.2019.4079","article-title":"Long-term outcomes of lung transplant with ex vivo lung perfusion","volume":"154","author":"Divithotawela","year":"2019","journal-title":"JAMA Surg"},{"issue":"8","key":"10.1016\/j.transproceed.2025.10.028_bib0059","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0255155","article-title":"Subnormothermic ex vivo lung perfusion attenuates ischemia reperfusion injury from donation after circulatory death donors","volume":"16","author":"Arni","year":"2021","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.transproceed.2025.10.028_bib0060","doi-asserted-by":"crossref","first-page":"2296","DOI":"10.3390\/cells10092296","article-title":"Ex vivo lung perfusion with K(ATP) channel modulators antagonize ischemia reperfusion injury","volume":"10","author":"Arni","year":"2021","journal-title":"Cells"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0061","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2022.848352","article-title":"The effect of hypothermic machine perfusion to ameliorate ischemia-reperfusion injury in donor organs","volume":"13","author":"Knijff","year":"2022","journal-title":"Front Immunol"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0062","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1097\/MAT.0000000000000550","article-title":"A leukocyte filter does not provide further benefit during ex vivo lung perfusion","volume":"63","author":"Luc","year":"2017","journal-title":"ASAIO J"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0063","doi-asserted-by":"crossref","first-page":"2841","DOI":"10.1097\/TP.0000000000001798","article-title":"Targeting circulating leukocytes and pyroptosis during ex vivo lung perfusion improves lung preservation","volume":"101","author":"Noda","year":"2017","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0064","doi-asserted-by":"crossref","first-page":"1287","DOI":"10.1016\/j.surg.2016.10.031","article-title":"Lung inflation with hydrogen sulfide during the warm ischemia phase ameliorates injury in rat donor lungs via metabolic inhibition after cardiac death","volume":"161","author":"Meng","year":"2017","journal-title":"Surgery"},{"issue":"2","key":"10.1016\/j.transproceed.2025.10.028_bib0065","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.jtcvs.2012.11.005","article-title":"Postmortem and ex vivo carbon monoxide ventilation reduces injury in rat lungs transplanted from non-heart-beating donors","volume":"146","author":"Dong","year":"2013","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"12","key":"10.1016\/j.transproceed.2025.10.028_bib0066","doi-asserted-by":"crossref","first-page":"2707","DOI":"10.1111\/j.1600-6143.2009.02840.x","article-title":"Nitric oxide ventilation of rat lungs from non-heart-beating donors improves posttransplant function","volume":"9","author":"Dong","year":"2009","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0067","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1016\/j.jss.2017.05.041","article-title":"The administration of argon during ex vivo normothermic perfusion in an experimental model of kidney ischemia-reperfusion injury","volume":"218","author":"Smith","year":"2017","journal-title":"J Surg Res"},{"issue":"5","key":"10.1016\/j.transproceed.2025.10.028_bib0068","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1016\/j.athoracsur.2016.10.062","article-title":"Sevoflurane attenuates ischemia-reperfusion injury in a rat lung transplantation model","volume":"103","author":"Ohsumi","year":"2017","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0069","doi-asserted-by":"crossref","first-page":"977","DOI":"10.1093\/icvts\/ivx438","article-title":"Experimental ex vivo lung perfusion with sevoflurane: effects on damaged donor lung grafts","volume":"26","author":"Wang","year":"2018","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0070","doi-asserted-by":"crossref","first-page":"148","DOI":"10.1111\/aor.14390","article-title":"Customized normothermic machine perfusion decreases ischemia\u2013reperfusion injury compared with static cold storage in a porcine model of liver transplantation","volume":"47","author":"Riveros","year":"2023","journal-title":"Artif Organs"},{"issue":"3","key":"10.1016\/j.transproceed.2025.10.028_bib0071","doi-asserted-by":"crossref","first-page":"e1450","DOI":"10.1097\/TXD.0000000000001450","article-title":"Normothermic regional perfusion can improve both utilization and outcomes in DCD liver, kidney, and pancreas transplantation","volume":"9","author":"Bekki","year":"2023","journal-title":"Transplant Direct"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0072","doi-asserted-by":"crossref","first-page":"987","DOI":"10.1016\/j.ajt.2023.04.021","article-title":"Six-month abdominal transplant recipient outcomes from donation after circulatory death heart donors: a retrospective analysis by procurement technique","volume":"23","author":"Wall","year":"2023","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0073","doi-asserted-by":"crossref","first-page":"516","DOI":"10.1097\/TP.0000000000004801","article-title":"Kidney donation after circulatory death using thoracoabdominal normothermic regional perfusion: the largest report of the United States experience","volume":"108","author":"Zhou","year":"2024","journal-title":"Transplantation"},{"issue":"3","key":"10.1016\/j.transproceed.2025.10.028_bib0074","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.15269","article-title":"Single center utilization and post-transplant outcomes of thoracoabdominal normothermic regional perfusion deceased cardiac donor organs","volume":"38","author":"Motter","year":"2024","journal-title":"Clin Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0075","doi-asserted-by":"crossref","first-page":"276","DOI":"10.3389\/fmed.2019.00276","article-title":"The first case of ischemia-free kidney transplantation in humans","volume":"6","author":"He","year":"2019","journal-title":"Front Med (Lausanne)"},{"issue":"3","key":"10.1016\/j.transproceed.2025.10.028_bib0076","doi-asserted-by":"crossref","first-page":"737","DOI":"10.1111\/ajt.14583","article-title":"The first case of ischemia-free organ transplantation in humans: a proof of concept","volume":"18","author":"He","year":"2018","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0077","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1159\/000501805","article-title":"Vein suturing results in worse lung graft outcomes compared to the cuff method","volume":"60","author":"Zampieri","year":"2019","journal-title":"Eur Surg Res"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0078","article-title":"Exploring alternative perfusion solutions using next-generation polymerized hemoglobin-based oxygen carriers in a model of rat ex vivo lung perfusion","volume":"208","author":"Gouchoe","year":"2024","journal-title":"J Vis Exp"},{"issue":"4","key":"10.1016\/j.transproceed.2025.10.028_bib0079","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1111\/ajt.15695","article-title":"Treatment with 3-aminobenzamide during ex vivo lung perfusion of damaged rat lungs reduces graft injury and dysfunction after transplantation","volume":"20","author":"Wang","year":"2020","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0080","doi-asserted-by":"crossref","first-page":"273","DOI":"10.1016\/j.jss.2019.07.057","article-title":"Enhanced mitochondrial dna repair resuscitates transplantable lungs donated after circulatory death","volume":"245","author":"Tan","year":"2020","journal-title":"J Surg Res"},{"issue":"3","key":"10.1016\/j.transproceed.2025.10.028_bib0081","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0173916","article-title":"Pyrrolidine dithiocarbamate administered during ex-vivo lung perfusion promotes rehabilitation of injured donor rat lungs obtained after prolonged warm ischemia","volume":"12","author":"Francioli","year":"2017","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.transproceed.2025.10.028_bib0082","doi-asserted-by":"crossref","first-page":"843","DOI":"10.3390\/antiox11050843","article-title":"Ex vivo lung perfusion with \u03b2-nicotinamide adenine dinucleotide (NAD+) improves ischemic lung function","volume":"11","author":"Ehrsam","year":"2022","journal-title":"Antioxidants"},{"issue":"1","key":"10.1016\/j.transproceed.2025.10.028_bib0083","first-page":"583","article-title":"Lung transplantation in the rat","volume":"3","author":"Asimacopoulos","year":"1971","journal-title":"Transplant Proc"},{"issue":"1","key":"10.1016\/j.transproceed.2025.10.028_bib0084","doi-asserted-by":"crossref","first-page":"74","DOI":"10.1016\/S0003-4975(10)60857-0","article-title":"Lung transplantation in the rat: I. Technique and survival","volume":"34","author":"Marck","year":"1982","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0085","doi-asserted-by":"crossref","first-page":"578","DOI":"10.1016\/S0022-5223(19)34549-0","article-title":"Simplified rat lung transplantation using a cuff technique","volume":"97","author":"Mizuta","year":"1989","journal-title":"J Thorac Cardiovasc Surg"},{"issue":"1","key":"10.1016\/j.transproceed.2025.10.028_bib0086","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1097\/00007890-198507000-00006","article-title":"Lung allograft rejection in the rat. I. Accelerated rejection caused by graft lymphocytes","volume":"40","author":"Prop","year":"1985","journal-title":"Transplantation"},{"issue":"2","key":"10.1016\/j.transproceed.2025.10.028_bib0087","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1097\/00007890-198508000-00003","article-title":"Lung allograft rejection in the rat. II. Specific immunological properties of lung grafts","volume":"40","author":"Prop","year":"1985","journal-title":"Transplantation"},{"issue":"2","key":"10.1016\/j.transproceed.2025.10.028_bib0088","doi-asserted-by":"crossref","first-page":"132","DOI":"10.1097\/00007890-198508000-00004","article-title":"Lung allograft rejection in the rat. III. Corresponding morphological rejection phases in various rat strain combinations","volume":"40","author":"Prop","year":"1985","journal-title":"Transplantation"},{"issue":"1","key":"10.1016\/j.transproceed.2025.10.028_bib0089","first-page":"168","article-title":"Lung allograft rejection in the rat. V. Inhaled stimuli aggravate the rejection response","volume":"132","author":"Prop","year":"1985","journal-title":"Am Rev Respir Dis"},{"issue":"4","key":"10.1016\/j.transproceed.2025.10.028_bib0090","doi-asserted-by":"crossref","first-page":"500","DOI":"10.1097\/00007890-200202270-00002","article-title":"Prevention of bronchiolitis obliterans in rat lung allografts by type V collagen-induced oral tolerance","volume":"73","author":"Yasufuku","year":"2002","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0091","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1016\/j.healun.2007.01.018","article-title":"Lung transplantation in the Fischer 344\u2192Wistar Kyoto rat strain combination is not suitable to study bronchiolitis obliterans","volume":"26","author":"Hirschburger","year":"2007","journal-title":"J Heart Lung Transplant"},{"issue":"11","key":"10.1016\/j.transproceed.2025.10.028_bib0092","doi-asserted-by":"crossref","first-page":"1509","DOI":"10.1097\/00007890-199506150-00002","article-title":"Assessment of pathological changes associated with chronic allograft rejection and tolerance in two experimental models of rat lung transplantation","volume":"59","author":"Matsumura","year":"1995","journal-title":"Transplantation"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0093","doi-asserted-by":"crossref","first-page":"99","DOI":"10.21037\/atm-22-42","article-title":"Normothermic ex vivo lung perfusion outperforms conventional cold preservation in a deceased rat lung","volume":"10","author":"Wang","year":"2022","journal-title":"Ann Transl Med"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0094","doi-asserted-by":"crossref","first-page":"1963","DOI":"10.1016\/j.jtcvs.2020.07.104","article-title":"Strategies to prolong homeostasis of ex vivo perfused lungs","volume":"161","author":"Takahashi","year":"2021","journal-title":"J Thorac Cardiovasc Surg"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0095","doi-asserted-by":"crossref","first-page":"E532","DOI":"10.1097\/TXD.0000000000000968","article-title":"Donor leukocyte trafficking and damage-associated molecular pattern expression during ex vivo lung perfusion","volume":"6","author":"Davis","year":"2020","journal-title":"Transplant Direct"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0096","doi-asserted-by":"crossref","first-page":"905","DOI":"10.1016\/j.healun.2021.05.015","article-title":"Effects of cold or warm ischemia and ex-vivo lung perfusion on the release of damage associated molecular patterns and inflammatory cytokines in experimental lung transplantation","volume":"40","author":"Hasenauer","year":"2021","journal-title":"J Heart Lung Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0097","doi-asserted-by":"crossref","first-page":"E368","DOI":"10.1097\/MAT.0000000000001988","article-title":"Biometric profiling to quantify lung injury through ex vivo lung perfusion following warm ischemia","volume":"69","author":"Kim","year":"2023","journal-title":"ASAIO J"},{"issue":"1","key":"10.1016\/j.transproceed.2025.10.028_bib0098","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.ccm.2022.10.006","article-title":"Expanding the lung donor pool: donation after circulatory death, ex-vivo lung perfusion and hepatitis C donors","volume":"44","author":"Saddoughi","year":"2023","journal-title":"Clin Chest Med"},{"issue":"4","key":"10.1016\/j.transproceed.2025.10.028_bib0099","doi-asserted-by":"crossref","first-page":"1195","DOI":"10.1111\/ajt.15237","article-title":"Excellent long-term outcome with lungs obtained from uncontrolled donation after circulatory death","volume":"19","author":"Suberviola","year":"2019","journal-title":"Am J Transplant"},{"key":"10.1016\/j.transproceed.2025.10.028_bib0100","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1111\/ajt.15795","article-title":"Initial lung transplantation experience with uncontrolled donation after cardiac death in North America","volume":"20","author":"Healey","year":"2020","journal-title":"Am J Transplant"},{"issue":"8","key":"10.1016\/j.transproceed.2025.10.028_bib0101","article-title":"Functional vascularized lung grafts for lung bioengineering","volume":"3","year":"2017","journal-title":"Science advances"}],"container-title":["Transplantation Proceedings"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134525005214?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041134525005214?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,6,7]],"date-time":"2026-06-07T08:24:00Z","timestamp":1780820640000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041134525005214"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12]]},"references-count":101,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2025,12]]}},"alternative-id":["S0041134525005214"],"URL":"https:\/\/doi.org\/10.1016\/j.transproceed.2025.10.028","relation":{},"ISSN":["0041-1345"],"issn-type":[{"value":"0041-1345","type":"print"}],"subject":[],"published":{"date-parts":[[2025,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Current Methodological Procedures in Rat Models After Circulatory Death","name":"articletitle","label":"Article Title"},{"value":"Transplantation Proceedings","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.transproceed.2025.10.028","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}