{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:12:40Z","timestamp":1790615560039,"version":"4.1.0"},"reference-count":42,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2018,12,8]],"date-time":"2018-12-08T00:00:00Z","timestamp":1544227200000},"content-version":"vor","delay-in-days":341,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100007601","name":"Horizon 2020","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100007601","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["alz-journals.onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["A&amp;D Transl Res &amp; Clin Interv"],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:title>Abstract<\/jats:title>\n                  <jats:sec>\n                    <jats:title>Introduction<\/jats:title>\n                    <jats:p>The Age\u2010Well observational, cross\u2010sectional study investigates the affective and cognitive mechanisms of meditation expertise with behavioral, neuroimaging, sleep, and biological measures sensitive to aging and Alzheimer's disease (AD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Thirty cognitively unimpaired individuals aged 65\u00a0years or older with at least 10,000\u00a0hours of practice in mindfulness meditation (MM) and loving\u2010kindness and compassion meditation (LKCM) are selected. The outcomes are the neuroimaging brain correlates of MM and LKCM and the assessments of long\u2010term meditation practices on behavioral, neural, and biological measures as compared to nonmeditator older controls from the Age\u2010Well randomized controlled trial.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Recruitment and data collection began in late 2016 and will be completed by late\u00a02019.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Discussion<\/jats:title>\n                    <jats:p>Results are expected to foster the understanding of the effects of meditation expertise on aging and of the mechanisms of action underlying the meditation intervention in the Age\u2010Well randomized controlled trial. These finding will contribute to the design of meditation\u2010based prevention randomized controlled trials for the aged population and to the exploration of the possible long\u2010time developmental trajectory of meditation training.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.1016\/j.trci.2018.11.002","type":"journal-article","created":{"date-parts":[[2018,12,18]],"date-time":"2018-12-18T12:36:52Z","timestamp":1545136612000},"page":"756-764","update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":17,"title":["The Age\u2010Well observational study on expert meditators in the Medit\u2010Ageing European project"],"prefix":"10.1002","volume":"4","author":[{"given":"Antoine","family":"Lutz","sequence":"first","affiliation":[{"name":"Lyon Neuroscience Research Center INSERM U1028 CNRS UMR5292 Lyon University Lyon France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Olga 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