{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:27:41Z","timestamp":1790821661306,"version":"4.1.0"},"reference-count":66,"publisher":"Elsevier BV","issue":"10","license":[{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,19]],"date-time":"2024-09-19T00:00:00Z","timestamp":1726704000000},"content-version":"am","delay-in-days":354,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,10,1]],"date-time":"2023-10-01T00:00:00Z","timestamp":1696118400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01CA240603"],"award-info":[{"award-number":["R01CA240603"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R01CA260205"],"award-info":[{"award-number":["R01CA260205"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100001790","name":"Ara Parseghian Medical Research Foundation","doi-asserted-by":"publisher","award":["R01CA240603"],"award-info":[{"award-number":["R01CA240603"]}],"id":[{"id":"10.13039\/100001790","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100008109","name":"University of Notre Dame","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100008109","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Cancer"],"published-print":{"date-parts":[[2023,10]]},"DOI":"10.1016\/j.trecan.2023.06.005","type":"journal-article","created":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T07:40:37Z","timestamp":1688197237000},"page":"817-827","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":34,"title":["Emerging roles of the MiT\/TFE factors in cancer"],"prefix":"10.1016","volume":"9","author":[{"given":"Roberto","family":"Zoncu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2435-2273","authenticated-orcid":false,"given":"Rushika M.","family":"Perera","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.trecan.2023.06.005_bb0005","doi-asserted-by":"crossref","first-page":"3474","DOI":"10.1200\/JCO.2010.32.6223","article-title":"Biology and clinical relevance of the micropthalmia family of transcription factors in human cancer","volume":"29","author":"Haq","year":"2011","journal-title":"J. Clin. Oncol."},{"key":"10.1016\/j.trecan.2023.06.005_bb0010","doi-asserted-by":"crossref","first-page":"2475","DOI":"10.1242\/jcs.146365","article-title":"TFEB at a glance","volume":"129","author":"Napolitano","year":"2016","journal-title":"J. Cell Sci."},{"key":"10.1016\/j.trecan.2023.06.005_bb0015","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1038\/ncb2718","article-title":"TFEB controls cellular lipid metabolism through a starvation-induced autoregulatory loop","volume":"15","author":"Settembre","year":"2013","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.trecan.2023.06.005_bb0020","doi-asserted-by":"crossref","first-page":"3852","DOI":"10.1093\/hmg\/ddr306","article-title":"Characterization of the CLEAR network reveals an integrated control of cellular clearance pathways","volume":"20","author":"Palmieri","year":"2011","journal-title":"Hum. Mol. Genet."},{"key":"10.1016\/j.trecan.2023.06.005_bb0025","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1126\/science.1174447","article-title":"A gene network regulating lysosomal biogenesis and function","volume":"325","author":"Sardiello","year":"2009","journal-title":"Science"},{"key":"10.1016\/j.trecan.2023.06.005_bb0030","doi-asserted-by":"crossref","first-page":"E420","DOI":"10.1073\/pnas.1424576112","article-title":"MITF drives endolysosomal biogenesis and potentiates Wnt signaling in melanoma cells","volume":"112","author":"Ploper","year":"2015","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"key":"10.1016\/j.trecan.2023.06.005_bb0035","doi-asserted-by":"crossref","first-page":"ra9","DOI":"10.1126\/scisignal.2004754","article-title":"The nutrient-responsive transcription factor TFE3 promotes autophagy, lysosomal biogenesis, and clearance of cellular debris","volume":"7","author":"Martina","year":"2014","journal-title":"Sci. Signal."},{"key":"10.1016\/j.trecan.2023.06.005_bb0040","doi-asserted-by":"crossref","DOI":"10.15252\/embj.2020105696","article-title":"MiT\/TFE factors control ER-phagy via transcriptional regulation of FAM134B","volume":"39","author":"Cinque","year":"2020","journal-title":"EMBO J."},{"key":"10.1016\/j.trecan.2023.06.005_bb0045","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1016\/j.molcel.2019.08.005","article-title":"Polyamines control eIF5A hypusination, TFEB translation, and autophagy to reverse B cell senescence","volume":"76","author":"Zhang","year":"2019","journal-title":"Mol. Cell"},{"key":"10.1016\/j.trecan.2023.06.005_bb0050","doi-asserted-by":"crossref","first-page":"1429","DOI":"10.1126\/science.1204592","article-title":"TFEB links autophagy to lysosomal biogenesis","volume":"332","author":"Settembre","year":"2011","journal-title":"Science"},{"key":"10.1016\/j.trecan.2023.06.005_bb0055","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1080\/15548627.2017.1313943","article-title":"Emerging roles for TFEB in the immune response and inflammation","volume":"14","author":"Brady","year":"2018","journal-title":"Autophagy"},{"key":"10.1016\/j.trecan.2023.06.005_bb0060","doi-asserted-by":"crossref","first-page":"632","DOI":"10.1038\/s41467-018-08020-0","article-title":"Folliculin regulates mTORC1\/2 and WNT pathways in early human pluripotency","volume":"10","author":"Mathieu","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.trecan.2023.06.005_bb0065","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1016\/j.cell.2013.03.012","article-title":"Exit from pluripotency is gated by intracellular redistribution of the bHLH transcription factor Tfe3","volume":"153","author":"Betschinger","year":"2013","journal-title":"Cell"},{"key":"10.1016\/j.trecan.2023.06.005_bb0070","doi-asserted-by":"crossref","first-page":"257","DOI":"10.1016\/j.stem.2018.11.021","article-title":"Lysosomal signaling licenses embryonic stem cell differentiation via inactivation of Tfe3","volume":"24","author":"Villegas","year":"2019","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.trecan.2023.06.005_bb0075","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1146\/annurev-cancerbio-030518-055835","article-title":"MiT\/TFE family of transcription factors, lysosomes, and cancer","volume":"3","author":"Perera","year":"2019","journal-title":"Annu. Rev. Cancer Biol."},{"key":"10.1016\/j.trecan.2023.06.005_bb0080","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.nbd.2018.05.012","article-title":"TFEB dysregulation as a driver of autophagy dysfunction in neurodegenerative disease: molecular mechanisms, cellular processes, and emerging therapeutic opportunities","volume":"122","author":"Cortes","year":"2019","journal-title":"Neurobiol. Dis."},{"key":"10.1016\/j.trecan.2023.06.005_bb0085","doi-asserted-by":"crossref","first-page":"934","DOI":"10.1093\/nar\/gkz1104","article-title":"Mechanism of conditional partner selectivity in MITF\/TFE family transcription factors with a conserved coiled coil stammer motif","volume":"48","author":"Pogenberg","year":"2020","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.trecan.2023.06.005_bb0090","doi-asserted-by":"crossref","first-page":"2647","DOI":"10.1101\/gad.198192.112","article-title":"Restricted leucine zipper dimerization and specificity of DNA recognition of the melanocyte master regulator MITF","volume":"26","author":"Pogenberg","year":"2012","journal-title":"Genes Dev."},{"key":"10.1016\/j.trecan.2023.06.005_bb0095","doi-asserted-by":"crossref","DOI":"10.15252\/embj.201798804","article-title":"The complex relationship between TFEB transcription factor phosphorylation and subcellular localization","volume":"37","author":"Puertollano","year":"2018","journal-title":"EMBO J."},{"key":"10.1016\/j.trecan.2023.06.005_bb0100","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/pcmr.12922","article-title":"User guide to MiT-TFE isoforms and post-translational modifications","volume":"34","author":"Vu","year":"2021","journal-title":"Pigment Cell Melanoma Res."},{"key":"10.1016\/j.trecan.2023.06.005_bb0105","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1038\/emboj.2012.32","article-title":"A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB","volume":"31","author":"Settembre","year":"2012","journal-title":"EMBO J."},{"key":"10.1016\/j.trecan.2023.06.005_bb0110","doi-asserted-by":"crossref","first-page":"903","DOI":"10.4161\/auto.19653","article-title":"MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB","volume":"8","author":"Martina","year":"2012","journal-title":"Autophagy"},{"key":"10.1016\/j.trecan.2023.06.005_bb0115","doi-asserted-by":"crossref","first-page":"ra42","DOI":"10.1126\/scisignal.2002790","article-title":"The transcription factor TFEB links mTORC1 signaling to transcriptional control of lysosome homeostasis","volume":"5","author":"Roczniak-Ferguson","year":"2012","journal-title":"Sci. Signal."},{"key":"10.1016\/j.trecan.2023.06.005_bb0120","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.devcel.2020.06.010","article-title":"The lysosome at the intersection of cellular growth and destruction","volume":"54","author":"Shin","year":"2020","journal-title":"Dev. Cell"},{"key":"10.1016\/j.trecan.2023.06.005_bb0125","doi-asserted-by":"crossref","first-page":"920","DOI":"10.1016\/j.tcb.2022.04.012","article-title":"Non-canonical mTORC1 signaling at the lysosome","volume":"32","author":"Napolitano","year":"2022","journal-title":"Trends Cell Biol."},{"key":"10.1016\/j.trecan.2023.06.005_bb0130","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1038\/s41586-020-2444-0","article-title":"A substrate-specific mTORC1 pathway underlies Birt-Hogg-Dube\u2019 syndrome","volume":"585","author":"Napolitano","year":"2020","journal-title":"Nature"},{"key":"10.1016\/j.trecan.2023.06.005_bb0135","doi-asserted-by":"crossref","first-page":"572","DOI":"10.1038\/s41586-022-05652-7","article-title":"Structure of the lysosomal mTORC1-TFEB-Rag-Ragulator megacomplex","volume":"614","author":"Cui","year":"2023","journal-title":"Nature"},{"key":"10.1016\/j.trecan.2023.06.005_bb0140","doi-asserted-by":"crossref","first-page":"1107","DOI":"10.1083\/jcb.201307084","article-title":"Recruitment of folliculin to lysosomes supports the amino acid-dependent activation of Rag GTPases","volume":"202","author":"Petit","year":"2013","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.trecan.2023.06.005_bb0145","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1126\/science.aax0364","article-title":"Structural mechanism of a Rag GTPase activation checkpoint by the lysosomal folliculin complex","volume":"366","author":"Lawrence","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.trecan.2023.06.005_bb0150","doi-asserted-by":"crossref","first-page":"495","DOI":"10.1016\/j.molcel.2013.09.016","article-title":"The folliculin tumor suppressor is a GAP for the RagC\/D GTPases that signal amino acid levels to mTORC1","volume":"52","author":"Tsun","year":"2013","journal-title":"Mol. Cell"},{"key":"10.1016\/j.trecan.2023.06.005_bb0155","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.add2926","article-title":"Structural basis for FLCN RagC GAP activation in MiT-TFE substrate-selective mTORC1 regulation","volume":"8","author":"Jansen","year":"2022","journal-title":"Sci. Adv."},{"key":"10.1016\/j.trecan.2023.06.005_bb0160","doi-asserted-by":"crossref","first-page":"5592","DOI":"10.1074\/jbc.M114.616714","article-title":"Glycogen synthase kinase-3 (GSK3) inhibition induces prosurvival autophagic signals in human pancreatic cancer cells","volume":"290","author":"Marchand","year":"2015","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.trecan.2023.06.005_bb0165","doi-asserted-by":"crossref","first-page":"955","DOI":"10.1101\/gad.213827.113","article-title":"A RANKL-PKC\u03b2-TFEB signaling cascade is necessary for lysosomal biogenesis in osteoclasts","volume":"27","author":"Ferron","year":"2013","journal-title":"Genes Dev."},{"key":"10.1016\/j.trecan.2023.06.005_bb0170","doi-asserted-by":"crossref","first-page":"3312","DOI":"10.1038\/s41467-018-05862-6","article-title":"mTOR-dependent phosphorylation controls TFEB nuclear export","volume":"9","author":"Napolitano","year":"2018","journal-title":"Nat. Commun."},{"key":"10.1016\/j.trecan.2023.06.005_bb0175","doi-asserted-by":"crossref","DOI":"10.1083\/jcb.201911036","article-title":"CDK4\/6 regulate lysosome biogenesis through TFEB\/TFE3","volume":"219","author":"Yin","year":"2020","journal-title":"J. Cell Biol."},{"key":"10.1016\/j.trecan.2023.06.005_bb0180","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/j.molcel.2019.10.016","article-title":"An mTORC1-to-CDK1 switch maintains autophagy suppression during mitosis","volume":"77","author":"Odle","year":"2020","journal-title":"Mol. Cell"},{"key":"10.1016\/j.trecan.2023.06.005_bb0185","doi-asserted-by":"crossref","first-page":"288","DOI":"10.1038\/ncb3114","article-title":"Lysosomal calcium signalling regulates autophagy through calcineurin and TFEB","volume":"17","author":"Medina","year":"2015","journal-title":"Nat. Cell Biol."},{"key":"10.1016\/j.trecan.2023.06.005_bb0190","doi-asserted-by":"crossref","first-page":"12525","DOI":"10.1074\/jbc.RA118.003471","article-title":"Protein phosphatase 2A stimulates activation of TFEB and TFE3 transcription factors in response to oxidative stress","volume":"293","author":"Martina","year":"2018","journal-title":"J. Biol. Chem."},{"key":"10.1016\/j.trecan.2023.06.005_bb0195","doi-asserted-by":"crossref","DOI":"10.1126\/science.abj5559","article-title":"Induction of lysosomal and mitochondrial biogenesis by AMPK phosphorylation of FNIP1","volume":"380","author":"Malik","year":"2023","journal-title":"Science"},{"key":"10.1016\/j.trecan.2023.06.005_bb0200","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1002\/jcp.24978","article-title":"Transcription factor Tfe3 directly regulates Pgc-1alpha in muscle","volume":"230","author":"Salma","year":"2015","journal-title":"J. Cell. Physiol."},{"key":"10.1016\/j.trecan.2023.06.005_bb0205","doi-asserted-by":"crossref","first-page":"2544","DOI":"10.15252\/embj.201796699","article-title":"STUB1 regulates TFEB-induced autophagy-lysosome pathway","volume":"36","author":"Sha","year":"2017","journal-title":"EMBO J."},{"key":"10.1016\/j.trecan.2023.06.005_bb0210","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/j.molcel.2022.12.013","article-title":"A central role for regulated protein stability in the control of TFE3 and MITF by nutrients","volume":"83","author":"Nardone","year":"2023","journal-title":"Mol. Cell"},{"key":"10.1016\/j.trecan.2023.06.005_bb0215","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1038\/nrurol.2014.162","article-title":"Molecular genetics and cellular features of TFE3 and TFEB fusion kidney cancers","volume":"11","author":"Kauffman","year":"2014","journal-title":"Nat. Rev. Urol."},{"key":"10.1016\/j.trecan.2023.06.005_bb0220","doi-asserted-by":"crossref","first-page":"3303","DOI":"10.1038\/s41388-021-01776-8","article-title":"Nuclear translocation of ASPL-TFE3 fusion protein creates favorable metabolism by mediating autophagy in translocation renal cell carcinoma","volume":"40","author":"Fang","year":"2021","journal-title":"Oncogene"},{"key":"10.1016\/j.trecan.2023.06.005_bb0225","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2021.110190","article-title":"Integrative clinical and molecular characterization of translocation renal cell carcinoma","volume":"38","author":"Bakouny","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.trecan.2023.06.005_bb0230","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1101\/gad.287524.116","article-title":"Recent insights into the function of autophagy in cancer","volume":"30","author":"Amaravadi","year":"2016","journal-title":"Genes Dev."},{"key":"10.1016\/j.trecan.2023.06.005_bb0235","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1007\/978-3-030-94004-1_2","article-title":"Macropinocytosis and cancer: from tumor stress to signaling pathways","volume":"98","author":"Lambies","year":"2022","journal-title":"Subcell. Biochem."},{"key":"10.1016\/j.trecan.2023.06.005_bb0240","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/nature14587","article-title":"Transcriptional control of autophagy-lysosome function drives pancreatic cancer metabolism","volume":"524","author":"Perera","year":"2015","journal-title":"Nature"},{"key":"10.1016\/j.trecan.2023.06.005_bb0245","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.cmet.2018.10.005","article-title":"Genetic analysis reveals AMPK is required to support tumor growth in murine Kras-dependent lung cancer models","volume":"29","author":"Eichner","year":"2019","journal-title":"Cell Metab."},{"key":"10.1016\/j.trecan.2023.06.005_bb0250","doi-asserted-by":"crossref","first-page":"2461","DOI":"10.1038\/s41467-020-16300-x","article-title":"TFEB regulates murine liver cell fate during development and regeneration","volume":"11","author":"Pastore","year":"2020","journal-title":"Nat. Commun."},{"key":"10.1016\/j.trecan.2023.06.005_bb0255","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.17047","article-title":"Modelling TFE renal cell carcinoma in mice reveals a critical role of WNT signaling","volume":"5","author":"Calcagn\u00ec","year":"2016","journal-title":"Elife"},{"key":"10.1016\/j.trecan.2023.06.005_bb0260","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1038\/nrurol.2015.206","article-title":"Molecular genetics and clinical features of Birt-Hogg-Dub\u00e9 syndrome","volume":"12","author":"Schmidt","year":"2015","journal-title":"Nat. Rev. Urol."},{"key":"10.1016\/j.trecan.2023.06.005_bb0265","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pgen.1009187","article-title":"Folliculin variants linked to Birt-Hogg-Dub\u00e9 syndrome are targeted for proteasomal degradation","volume":"16","author":"Clausen","year":"2020","journal-title":"PLoS Genet."},{"key":"10.1016\/j.trecan.2023.06.005_bb0270","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0015793","article-title":"Inactivation of the FLCN tumor suppressor gene induces TFE3 transcriptional activity by increasing its nuclear localization","volume":"5","author":"Hong","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.trecan.2023.06.005_bb0275","doi-asserted-by":"crossref","first-page":"1188","DOI":"10.1126\/science.aag2553","article-title":"Transcriptional activation of RagD GTPase controls mTORC1 and promotes cancer growth","volume":"356","author":"Di Malta","year":"2017","journal-title":"Science"},{"key":"10.1016\/j.trecan.2023.06.005_bb0280","doi-asserted-by":"crossref","DOI":"10.15252\/emmm.202216877","article-title":"TFEB and TFE3 drive kidney cystogenesis and tumorigenesis","volume":"15","author":"Di Malta","year":"2023","journal-title":"EMBO Mol. Med."},{"key":"10.1016\/j.trecan.2023.06.005_bb0285","doi-asserted-by":"crossref","first-page":"4245","DOI":"10.1038\/s41467-021-24499-6","article-title":"TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism","volume":"12","author":"Alesi","year":"2021","journal-title":"Nat. Commun."},{"key":"10.1016\/j.trecan.2023.06.005_bb0290","doi-asserted-by":"crossref","DOI":"10.1172\/JCI144871","article-title":"Folliculin impairs breast tumor growth by repressing TFE3-dependent induction of the Warburg effect and angiogenesis","volume":"131","author":"El-Houjeiri","year":"2021","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.trecan.2023.06.005_bb0295","doi-asserted-by":"crossref","first-page":"162","DOI":"10.1158\/2643-3230.BCD-20-0029","article-title":"TFEB links MYC signaling to epigenetic control of myeloid differentiation and acute myeloid leukemia","volume":"2","author":"Yun","year":"2021","journal-title":"Blood Cancer Discov."},{"key":"10.1016\/j.trecan.2023.06.005_bb0300","doi-asserted-by":"crossref","first-page":"1234","DOI":"10.1158\/0008-5472.CAN-21-1168","article-title":"Disrupting the MYC-TFEB circuit impairs amino acid homeostasis and provokes metabolic anergy","volume":"82","author":"Fernandez","year":"2022","journal-title":"Cancer Res."},{"key":"10.1016\/j.trecan.2023.06.005_bb0305","doi-asserted-by":"crossref","first-page":"3623","DOI":"10.1038\/s41467-019-11568-0","article-title":"MYC competes with MiT\/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat","volume":"10","author":"Annunziata","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.trecan.2023.06.005_bb0310","doi-asserted-by":"crossref","first-page":"15008","DOI":"10.1038\/cddiscovery.2015.8","article-title":"Autophagy limits proliferation and glycolytic metabolism in acute myeloid leukemia","volume":"1","author":"Watson","year":"2015","journal-title":"Cell Death Discov."},{"key":"10.1016\/j.trecan.2023.06.005_bb0315","doi-asserted-by":"crossref","first-page":"1838","DOI":"10.1016\/j.stem.2021.07.003","article-title":"TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate","volume":"28","author":"Garc\u00eda-Prat","year":"2021","journal-title":"Cell Stem Cell"},{"key":"10.1016\/j.trecan.2023.06.005_bb0320","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/s41568-021-00367-9","article-title":"MYC protein interactors in gene transcription and cancer","volume":"21","author":"Lourenco","year":"2021","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.trecan.2023.06.005_bb0325","doi-asserted-by":"crossref","first-page":"2198","DOI":"10.1158\/2159-8290.CD-22-0044","article-title":"Coordinated transcriptional and catabolic programs support iron-dependent adaptation to RAS-MAPK pathway inhibition in pancreatic cancer","volume":"12","author":"Ravichandran","year":"2022","journal-title":"Cancer Discov."},{"key":"10.1016\/j.trecan.2023.06.005_bb0330","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1038\/s41420-020-0246-7","article-title":"TFEB-mediated lysosomal biogenesis and lysosomal drug sequestration confer resistance to MEK inhibition in pancreatic cancer","volume":"6","author":"Zhao","year":"2020","journal-title":"Cell Death Discov."}],"container-title":["Trends in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405803323001061?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405803323001061?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T21:53:50Z","timestamp":1778882030000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405803323001061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,10]]},"references-count":66,"journal-issue":{"issue":"10","published-print":{"date-parts":[[2023,10]]}},"alternative-id":["S2405803323001061"],"URL":"https:\/\/doi.org\/10.1016\/j.trecan.2023.06.005","relation":{},"ISSN":["2405-8033"],"issn-type":[{"value":"2405-8033","type":"print"}],"subject":[],"published":{"date-parts":[[2023,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Emerging roles of the MiT\/TFE factors in cancer","name":"articletitle","label":"Article Title"},{"value":"Trends in Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trecan.2023.06.005","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}