{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,17]],"date-time":"2026-06-17T23:50:49Z","timestamp":1781740249587,"version":"3.54.5"},"reference-count":58,"publisher":"Elsevier BV","issue":"12","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,9,5]],"date-time":"2024-09-05T00:00:00Z","timestamp":1725494400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Cancer"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.trecan.2024.09.002","type":"journal-article","created":{"date-parts":[[2024,9,28]],"date-time":"2024-09-28T21:41:08Z","timestamp":1727559668000},"page":"1095-1105","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":16,"title":["EZHIP\u2019s role in diffuse midline glioma: echoes of oncohistones?"],"prefix":"10.1016","volume":"10","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5257-8056","authenticated-orcid":false,"given":"Afraah","family":"Cassim","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9063-5370","authenticated-orcid":false,"given":"Matthew D.","family":"Dun","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2347-7835","authenticated-orcid":false,"given":"David","family":"Gallego-Ortega","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7490-0114","authenticated-orcid":false,"given":"Fatima","family":"Valdes-Mora","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.trecan.2024.09.002_bb0005","doi-asserted-by":"crossref","first-page":"3858","DOI":"10.1038\/s41467-019-11800-x","article-title":"EZHIP constrains polycomb repressive complex 2 activity in germ cells","volume":"10","author":"Ragazzini","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.trecan.2024.09.002_bb0010","doi-asserted-by":"crossref","DOI":"10.1172\/jci.insight.86837","article-title":"Profiling cancer testis antigens in non-small-cell lung cancer","volume":"1","author":"Djureinovic","year":"2016","journal-title":"JCI Insight"},{"key":"10.1016\/j.trecan.2024.09.002_bb0015","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1038\/nrc1669","article-title":"Cancer\/testis antigens, gametogenesis and cancer","volume":"5","author":"Simpson","year":"2005","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.trecan.2024.09.002_bb0020","doi-asserted-by":"crossref","first-page":"1112","DOI":"10.1002\/ijc.28440","article-title":"Identification of a novel, recurrent MBTD1-CXorf67 fusion in low-grade endometrial stromal sarcoma","volume":"134","author":"Dewaele","year":"2014","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.trecan.2024.09.002_bb0025","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aax2887","article-title":"CATACOMB: an endogenous inducible gene that antagonizes H3K27 methylation activity of polycomb repressive complex 2 via an H3K27M-like mechanism","volume":"5","author":"Piunti","year":"2019","journal-title":"Sci. Adv."},{"key":"10.1016\/j.trecan.2024.09.002_bb0030","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1111\/neup.12893","article-title":"An EWSR1-EZHIP fusion in a cerebral hemisphere astroblastoma","volume":"43","author":"Liu","year":"2023","journal-title":"Neuropathology"},{"key":"10.1016\/j.trecan.2024.09.002_bb0035","doi-asserted-by":"crossref","first-page":"211","DOI":"10.1007\/s00401-018-1877-0","article-title":"Molecular heterogeneity and CXorf67 alterations in posterior fossa group A (PFA) ependymomas","volume":"136","author":"Pajtler","year":"2018","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.trecan.2024.09.002_bb0040","doi-asserted-by":"crossref","first-page":"624","DOI":"10.3390\/genes13040624","article-title":"Pediatric high grade glioma classification criteria and molecular features of a case series","volume":"13","author":"Buccoliero","year":"2022","journal-title":"Genes (Basel)"},{"key":"10.1016\/j.trecan.2024.09.002_bb0045","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1016\/j.jid.2023.02.038","article-title":"Distinct regulation of EZH2 and its repressive H3K27me3 mark in polyomavirus-positive and -negative Merkel cell carcinoma","volume":"143","author":"Durand","year":"2023","journal-title":"J. Invest. Dermatol."},{"key":"10.1016\/j.trecan.2024.09.002_bb0050","doi-asserted-by":"crossref","first-page":"4926","DOI":"10.1016\/j.cell.2024.06.023","article-title":"TULIPs decorate the three-dimensional genome of PFA ependymoma","volume":"187","author":"Johnston","year":"2024","journal-title":"Cell"},{"key":"10.1016\/j.trecan.2024.09.002_bb0055","doi-asserted-by":"crossref","first-page":"2146","DOI":"10.1038\/s41467-019-09981-6","article-title":"PFA ependymoma-associated protein EZHIP inhibits PRC2 activity through a H3 K27M-like mechanism","volume":"10","author":"Jain","year":"2019","journal-title":"Nat. Commun."},{"key":"10.1016\/j.trecan.2024.09.002_bb0060","doi-asserted-by":"crossref","first-page":"3775","DOI":"10.1038\/s41598-023-30395-4","article-title":"Histone H3-wild type diffuse midline gliomas with H3K27me3 loss are a distinct entity with exclusive EGFR or ACVR1 mutation and differential methylation of homeobox genes","volume":"13","author":"Ajuyah","year":"2023","journal-title":"Sci. Rep."},{"key":"10.1016\/j.trecan.2024.09.002_bb0065","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1007\/s00401-020-02142-w","article-title":"Histone H3 wild-type DIPG\/DMG overexpressing EZHIP extend the spectrum diffuse midline gliomas with PRC2 inhibition beyond H3-K27M mutation","volume":"139","author":"Castel","year":"2020","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.trecan.2024.09.002_bb0070","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1186\/s40478-020-00905-w","article-title":"Diffuse intrinsic pontine glioma-like tumor with EZHIP expression and molecular features of PFA ependymoma","volume":"8","author":"Pratt","year":"2020","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.trecan.2024.09.002_bb0075","doi-asserted-by":"crossref","first-page":"1231","DOI":"10.1093\/neuonc\/noab106","article-title":"The 2021 WHO Classification of Tumors of the Central Nervous System: a summary","volume":"23","author":"Louis","year":"2021","journal-title":"Neuro-Oncology"},{"key":"10.1016\/j.trecan.2024.09.002_bb0080","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1126\/science.1232245","article-title":"Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma","volume":"340","author":"Lewis","year":"2013","journal-title":"Science"},{"key":"10.1016\/j.trecan.2024.09.002_bb0085","doi-asserted-by":"crossref","first-page":"30","DOI":"10.1007\/s10014-020-00385-9","article-title":"EZH2 inhibitory protein (EZHIP\/Cxorf67) expression correlates strongly with H3K27me3 loss in posterior fossa ependymomas and is mutually exclusive with H3K27M mutations","volume":"38","author":"Nambirajan","year":"2021","journal-title":"Brain Tumor Pathol."},{"key":"10.1016\/j.trecan.2024.09.002_bb0090","doi-asserted-by":"crossref","first-page":"878","DOI":"10.1093\/neuonc\/noz058","article-title":"EZHIP\/CXorf67 mimics K27M mutated oncohistones and functions as an intrinsic inhibitor of PRC2 function in aggressive posterior fossa ependymoma","volume":"21","author":"Hubner","year":"2019","journal-title":"Neuro-Oncology"},{"key":"10.1016\/j.trecan.2024.09.002_bb0095","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.aau5935","article-title":"Multiple modes of PRC2 inhibition elicit global chromatin alterations in H3K27M pediatric glioma","volume":"4","author":"Stafford","year":"2018","journal-title":"Sci. Adv."},{"key":"10.1016\/j.trecan.2024.09.002_bb0100","doi-asserted-by":"crossref","DOI":"10.1038\/ncomms11316","article-title":"Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2","volume":"7","author":"Justin","year":"2016","journal-title":"Nat. Commun."},{"key":"10.1016\/j.trecan.2024.09.002_bb0105","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1038\/nm.4296","article-title":"Therapeutic targeting of polycomb and BET bromodomain proteins in diffuse intrinsic pontine gliomas","volume":"23","author":"Piunti","year":"2017","journal-title":"Nat. Med."},{"key":"10.1016\/j.trecan.2024.09.002_bb0110","doi-asserted-by":"crossref","first-page":"726","DOI":"10.1016\/j.molcel.2020.09.028","article-title":"H3 K27M and EZHIP impede H3K27-methylation spreading by inhibiting allosterically stimulated PRC2","volume":"80","author":"Jain","year":"2020","journal-title":"Mol. Cell"},{"key":"10.1016\/j.trecan.2024.09.002_bb0115","doi-asserted-by":"crossref","DOI":"10.7554\/eLife.36696","article-title":"H3.3K27M mutant proteins reprogram epigenome by sequestering the PRC2 complex to poised enhancers","volume":"7","author":"Fang","year":"2018","journal-title":"eLife"},{"key":"10.1016\/j.trecan.2024.09.002_bb0120","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1038\/s41592-020-01052-9","article-title":"Decoding the protein composition of whole nucleosomes with Nuc-MS","volume":"18","author":"Schachner","year":"2021","journal-title":"Nat. Methods"},{"key":"10.1016\/j.trecan.2024.09.002_bb0125","article-title":"Epigenomic landscape and 3D genome structure in pediatric high-grade glioma","volume":"7","author":"Wang","year":"2021","journal-title":"Sci. Adv."},{"key":"10.1016\/j.trecan.2024.09.002_bb0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2022.110836","article-title":"H3-K27M-mutant nucleosomes interact with MLL1 to shape the glioma epigenetic landscape","volume":"39","author":"Furth","year":"2022","journal-title":"Cell Rep."},{"key":"10.1016\/j.trecan.2024.09.002_bb0135","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1093\/nar\/gkac800","article-title":"PRC2-independent actions of H3.3K27M in embryonic stem cell differentiation","volume":"51","author":"Cohen","year":"2023","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.trecan.2024.09.002_bb0140","doi-asserted-by":"crossref","first-page":"782","DOI":"10.1016\/j.ccell.2019.04.004","article-title":"Pervasive H3K27 acetylation leads to ERV expression and a therapeutic vulnerability in H3K27M gliomas","volume":"35","author":"Krug","year":"2019","journal-title":"Cancer Cell"},{"key":"10.1016\/j.trecan.2024.09.002_bb0145","doi-asserted-by":"crossref","first-page":"2","DOI":"10.1007\/s00401-023-02651-4","article-title":"A new subtype of diffuse midline glioma, H3 K27 and BRAF\/FGFR1 co-altered: a clinico-radiological and histomolecular characterisation","volume":"147","author":"Auffret","year":"2023","journal-title":"Acta Neuropathol."},{"key":"10.1016\/j.trecan.2024.09.002_bb0150","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1186\/s40478-023-01514-z","article-title":"Common molecular features of H3K27M DMGs and PFA ependymomas map to hindbrain developmental pathways","volume":"11","author":"Pun","year":"2023","journal-title":"Acta Neuropathol. Commun."},{"key":"10.1016\/j.trecan.2024.09.002_bb0155","doi-asserted-by":"crossref","first-page":"1221","DOI":"10.1038\/s41588-021-00897-w","article-title":"Simultaneous disruption of PRC2 and enhancer function underlies histone H3.3-K27M oncogenic activity in human hindbrain neural stem cells","volume":"53","author":"Brien","year":"2021","journal-title":"Nat. Genet."},{"key":"10.1016\/j.trecan.2024.09.002_bb0160","doi-asserted-by":"crossref","first-page":"965","DOI":"10.1016\/j.molcel.2019.08.030","article-title":"Histone variant and cell context determine H3K27M reprogramming of the enhancer landscape and oncogenic state","volume":"76","author":"Nagaraja","year":"2019","journal-title":"Mol. Cell"},{"key":"10.1016\/j.trecan.2024.09.002_bb0165","doi-asserted-by":"crossref","first-page":"1865","DOI":"10.1038\/s41588-022-01205-w","article-title":"K27M in canonical and noncanonical H3 variants occurs in distinct oligodendroglial cell lineages in brain midline gliomas","volume":"54","author":"Jessa","year":"2022","journal-title":"Nat. Genet."},{"key":"10.1016\/j.trecan.2024.09.002_bb0170","doi-asserted-by":"crossref","first-page":"1881","DOI":"10.1038\/s41588-022-01236-3","article-title":"The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location","volume":"54","author":"Liu","year":"2022","journal-title":"Nat. Genet."},{"key":"10.1016\/j.trecan.2024.09.002_bb0175","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1126\/science.aao4750","article-title":"Developmental and oncogenic programs in H3K27M gliomas dissected by single-cell RNA-seq","volume":"360","author":"Filbin","year":"2018","journal-title":"Science"},{"key":"10.1016\/j.trecan.2024.09.002_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.celrep.2020.108023","article-title":"Single-cell RNA sequencing of childhood ependymoma reveals neoplastic cell subpopulations that impact molecular classification and etiology","volume":"32","author":"Gillen","year":"2020","journal-title":"Cell Rep."},{"key":"10.1016\/j.trecan.2024.09.002_bb0185","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1016\/j.ccell.2020.06.004","article-title":"Single-cell RNA-seq reveals cellular hierarchies and impaired developmental trajectories in pediatric ependymoma","volume":"38","author":"Gojo","year":"2020","journal-title":"Cancer Cell"},{"key":"10.1016\/j.trecan.2024.09.002_bb0190","doi-asserted-by":"crossref","DOI":"10.1111\/bpa.13181","article-title":"The pontine diffuse midline glioma, EGFR-subtype with ependymal features: yet another face of diffuse midline glioma, H3K27-altered","volume":"34","author":"Tauziede-Espariat","year":"2024","journal-title":"Brain Pathol."},{"key":"10.1016\/j.trecan.2024.09.002_bb0195","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1093\/neuonc\/noaa251","article-title":"A subset of pediatric-type thalamic gliomas share a distinct DNA methylation profile, H3K27me3 loss and frequent alteration of EGFR","volume":"23","author":"Sievers","year":"2021","journal-title":"Neuro-Oncology"},{"key":"10.1016\/j.trecan.2024.09.002_bb0200","doi-asserted-by":"crossref","DOI":"10.1126\/science.adf1226","article-title":"Comprehensive cell atlas of the first-trimester developing human brain","volume":"382","author":"Braun","year":"2023","journal-title":"Science"},{"key":"10.1016\/j.trecan.2024.09.002_bb0205","doi-asserted-by":"crossref","first-page":"259","DOI":"10.3171\/2008.11.PEDS08281","article-title":"Treatment of diffuse intrinsic brainstem gliomas: failed approaches and future strategies","volume":"3","author":"Frazier","year":"2009","journal-title":"J. Neurosurg. Pediatr."},{"key":"10.1016\/j.trecan.2024.09.002_bb0210","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1038\/s41392-019-0101-6","article-title":"PROTACs: great opportunities for academia and industry","volume":"4","author":"Sun","year":"2019","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.trecan.2024.09.002_bb0215","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1038\/nm.4293","article-title":"EZH2 is a potential therapeutic target for H3K27M-mutant pediatric gliomas","volume":"23","author":"Mohammad","year":"2017","journal-title":"Nat. Med."},{"key":"10.1016\/j.trecan.2024.09.002_bb0220","doi-asserted-by":"crossref","first-page":"1329","DOI":"10.1016\/j.cell.2020.04.047","article-title":"Metabolic regulation of the epigenome drives lethal infantile ependymoma","volume":"181","author":"Michealraj","year":"2020","journal-title":"Cell"},{"key":"10.1016\/j.trecan.2024.09.002_bb0225","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1038\/nm.3855","article-title":"Functionally defined therapeutic targets in diffuse intrinsic pontine glioma","volume":"21","author":"Grasso","year":"2015","journal-title":"Nat. Med."},{"key":"10.1016\/j.trecan.2024.09.002_bb0230","doi-asserted-by":"crossref","first-page":"493","DOI":"10.1007\/s00280-018-3634-4","article-title":"A phase I study of panobinostat in pediatric patients with refractory solid tumors, including CNS tumors","volume":"82","author":"Wood","year":"2018","journal-title":"Cancer Chemother. Pharmacol."},{"key":"10.1016\/j.trecan.2024.09.002_bb0235","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1038\/s41388-021-02102-y","article-title":"Pharmaco-proteogenomic profiling of pediatric diffuse midline glioma to inform future treatment strategies","volume":"41","author":"Findlay","year":"2022","journal-title":"Oncogene"},{"key":"10.1016\/j.trecan.2024.09.002_bb0240","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1038\/s42003-019-0420-8","article-title":"ALK2 inhibitors display beneficial effects in preclinical models of ACVR1 mutant diffuse intrinsic pontine glioma","volume":"2","author":"Carvalho","year":"2019","journal-title":"Commun. Biol."},{"key":"10.1016\/j.trecan.2024.09.002_bb0245","doi-asserted-by":"crossref","first-page":"439","DOI":"10.1038\/s41419-018-0463-7","article-title":"APR-246 reactivates mutant p53 by targeting cysteines 124 and 277","volume":"9","author":"Zhang","year":"2018","journal-title":"Cell Death Dis."},{"key":"10.1016\/j.trecan.2024.09.002_bb0250","doi-asserted-by":"crossref","DOI":"10.1126\/scitranslmed.abc0497","article-title":"Targeting integrated epigenetic and metabolic pathways in lethal childhood PFA ependymomas","volume":"13","author":"Panwalkar","year":"2021","journal-title":"Sci. Transl. Med."},{"key":"10.1016\/j.trecan.2024.09.002_bb0255","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1038\/s43018-022-00348-3","article-title":"Loss of MAT2A compromises methionine metabolism and represents a vulnerability in H3K27M mutant glioma by modulating the epigenome","volume":"3","author":"Golbourn","year":"2022","journal-title":"Nat. Can."},{"key":"10.1016\/j.trecan.2024.09.002_bb0260","doi-asserted-by":"crossref","first-page":"2370","DOI":"10.1158\/2159-8290.CD-23-0131","article-title":"Clinical efficacy of ONC201 in H3K27M-mutant diffuse midline gliomas is driven by disruption of integrated metabolic and epigenetic pathways","volume":"13","author":"Venneti","year":"2023","journal-title":"Cancer Discov."},{"key":"10.1016\/j.trecan.2024.09.002_bb0265","doi-asserted-by":"crossref","first-page":"2421","DOI":"10.1158\/0008-5472.CAN-23-0186","article-title":"ONC201 in combination with paxalisib for the treatment of H3K27-altered diffuse midline glioma","author":"Jackson","year":"2023","journal-title":"Cancer Res."},{"key":"10.1016\/j.trecan.2024.09.002_bb0270","doi-asserted-by":"crossref","DOI":"10.1172\/JCI170329","article-title":"PI3K\/mTOR is a therapeutically targetable genetic dependency in diffuse intrinsic pontine glioma","volume":"134","author":"Duchatel","year":"2024","journal-title":"J. Clin. Invest."},{"key":"10.1016\/j.trecan.2024.09.002_bb0275","doi-asserted-by":"crossref","first-page":"844","DOI":"10.1016\/j.ccell.2020.10.009","article-title":"Elevated CXorf67 expression in PFA ependymomas suppresses DNA repair and sensitizes to PARP inhibitors","volume":"38","author":"Han","year":"2020","journal-title":"Cancer Cell"},{"key":"10.1016\/j.trecan.2024.09.002_bb0280","doi-asserted-by":"crossref","first-page":"2735","DOI":"10.1158\/1535-7163.MCT-17-0365","article-title":"Restricted delivery of talazoparib across the blood-brain barrier limits the sensitizing effects of PARP inhibition on temozolomide therapy in glioblastoma","volume":"16","author":"Kizilbash","year":"2017","journal-title":"Mol. Cancer Ther."},{"key":"10.1016\/j.trecan.2024.09.002_bb0285","doi-asserted-by":"crossref","first-page":"15772","DOI":"10.18632\/oncotarget.4694","article-title":"Oncogenic cancer\/testis antigens: prime candidates for immunotherapy","volume":"6","author":"Gjerstorff","year":"2015","journal-title":"Oncotarget"},{"key":"10.1016\/j.trecan.2024.09.002_bb0290","doi-asserted-by":"crossref","first-page":"2603","DOI":"10.1002\/1878-0261.13474","article-title":"Expression of cancer-testis antigens in the immune microenvironment of non-small cell lung cancer","volume":"17","author":"Hikmet","year":"2023","journal-title":"Mol. Oncol."}],"container-title":["Trends in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405803324001912?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405803324001912?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,12,9]],"date-time":"2024-12-09T19:49:36Z","timestamp":1733773776000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405803324001912"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":58,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2024,12]]}},"alternative-id":["S2405803324001912"],"URL":"https:\/\/doi.org\/10.1016\/j.trecan.2024.09.002","relation":{},"ISSN":["2405-8033"],"issn-type":[{"value":"2405-8033","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"EZHIP\u2019s role in diffuse midline glioma: echoes of oncohistones?","name":"articletitle","label":"Article Title"},{"value":"Trends in Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trecan.2024.09.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Author(s). Published by Elsevier Inc.","name":"copyright","label":"Copyright"}]}}