{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T21:04:42Z","timestamp":1789592682634,"version":"build-2803163510"},"reference-count":10,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,9,1]],"date-time":"2026-09-01T00:00:00Z","timestamp":1788220800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100010877","name":"Shenzhen Science and Technology Innovation Commission","doi-asserted-by":"publisher","award":["JCYJ20250604183359078"],"award-info":[{"award-number":["JCYJ20250604183359078"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017596","name":"Natural Science Basic Research Program of Shaanxi Province","doi-asserted-by":"publisher","award":["2026JC-YXQN-291"],"award-info":[{"award-number":["2026JC-YXQN-291"]}],"id":[{"id":"10.13039\/501100017596","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100017610","name":"Shenzhen Science and Technology Innovation Program","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100017610","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["22577101"],"award-info":[{"award-number":["22577101"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["cell.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Trends in Cancer"],"published-print":{"date-parts":[[2026,9]]},"DOI":"10.1016\/j.trecan.2026.08.011","type":"journal-article","created":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T11:36:52Z","timestamp":1789472212000},"update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"title":["Lkb1 loss links dietary lipids to cancer cachexia"],"prefix":"10.1016","author":[{"given":"Xiaolin","family":"Liu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiayi","family":"Shen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7180-7176","authenticated-orcid":false,"given":"Gaofei","family":"Wei","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.trecan.2026.08.011_bb0005","doi-asserted-by":"crossref","first-page":"913","DOI":"10.1016\/j.ccell.2026.03.012","article-title":"Cancer cachexia: a tumor-driven disorder of whole-body homeostasis","volume":"44","author":"Zhang","year":"2026","journal-title":"Cancer Cell"},{"key":"10.1016\/j.trecan.2026.08.011_bb0010","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1038\/s41392-025-02331-7","article-title":"Cancer cachexia: molecular basis and therapeutic advances","volume":"11","author":"Tan","year":"2026","journal-title":"Signal Transduct. Target. Ther."},{"key":"10.1016\/j.trecan.2026.08.011_bb0015","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1038\/s41586-025-09502-0","article-title":"Molecular subtypes of human skeletal muscle in cancer cachexia","volume":"646","author":"Bhatt","year":"2025","journal-title":"Nature"},{"key":"10.1016\/j.trecan.2026.08.011_bb0020","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1126\/science.adz4196","article-title":"A dietary switch promotes sensory neuron-dependent cancer-associated cachexia","volume":"393","author":"Cross","year":"2026","journal-title":"Science"},{"key":"10.1016\/j.trecan.2026.08.011_bb0025","doi-asserted-by":"crossref","DOI":"10.1126\/science.adm8857","article-title":"A neuroimmune circuit mediates cancer cachexia-associated apathy","volume":"388","author":"Zhu","year":"2025","journal-title":"Science"},{"key":"10.1016\/j.trecan.2026.08.011_bb0030","doi-asserted-by":"crossref","first-page":"949","DOI":"10.1016\/j.ccell.2026.01.014","article-title":"Tumor-immune-neural circuit disrupts energy homeostasis in cancer cachexia","volume":"44","author":"Shi","year":"2026","journal-title":"Cancer Cell"},{"key":"10.1016\/j.trecan.2026.08.011_bb0035","doi-asserted-by":"crossref","first-page":"2182","DOI":"10.1038\/s41467-026-68702-y","article-title":"Cancer cachexia in STK11\/LKB1-mutated non-small cell lung cancer is dependent on tumor-secreted GDF15","volume":"17","author":"Yu","year":"2026","journal-title":"Nat. Commun."},{"key":"10.1016\/j.trecan.2026.08.011_bb0040","doi-asserted-by":"crossref","first-page":"909","DOI":"10.1016\/j.immuni.2025.03.002","article-title":"Tumor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer","volume":"58","author":"Yu","year":"2025","journal-title":"Immunity"},{"key":"10.1016\/j.trecan.2026.08.011_bb0045","doi-asserted-by":"crossref","first-page":"1530","DOI":"10.1016\/j.cmet.2025.04.018","article-title":"Semaglutide effects on energy balance are mediated by Adcyap1+ neurons in the dorsal vagal complex","volume":"37","author":"Teixidor-Deulofeu","year":"2025","journal-title":"Cell Metab."},{"key":"10.1016\/j.trecan.2026.08.011_bb0050","doi-asserted-by":"crossref","DOI":"10.1126\/science.adm9805","article-title":"Direct sensing of dietary \u03c9-6 linoleic acid through FABP5-mTORC1 signaling","volume":"387","author":"Koundouros","year":"2025","journal-title":"Science"}],"container-title":["Trends in Cancer"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405803326002074?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2405803326002074?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T20:11:06Z","timestamp":1789589466000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2405803326002074"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9]]},"references-count":10,"alternative-id":["S2405803326002074"],"URL":"https:\/\/doi.org\/10.1016\/j.trecan.2026.08.011","relation":{},"ISSN":["2405-8033"],"issn-type":[{"value":"2405-8033","type":"print"}],"subject":[],"published":{"date-parts":[[2026,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Lkb1 loss links dietary lipids to cancer cachexia","name":"articletitle","label":"Article Title"},{"value":"Trends in Cancer","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trecan.2026.08.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}