{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T18:40:47Z","timestamp":1760812847939,"version":"build-2065373602"},"reference-count":22,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,4,1]],"date-time":"2021-04-01T00:00:00Z","timestamp":1617235200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100010564","name":"Deutsche Zentrum f\u00fcr Lungenforschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010564","name":"Deutsche Zentrum f\u00fcr Lungenforschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010564","name":"Deutsche Zentrum f\u00fcr Lungenforschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010564","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010564","name":"Deutsche Zentrum f\u00fcr Lungenforschung","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100010564","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transplant Immunology"],"published-print":{"date-parts":[[2021,4]]},"DOI":"10.1016\/j.trim.2020.101350","type":"journal-article","created":{"date-parts":[[2020,10,27]],"date-time":"2020-10-27T13:07:04Z","timestamp":1603804024000},"page":"101350","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Delayed non-myeloablative irradiation to induce long-term allograft acceptance in a large animal lung transplantation model"],"prefix":"10.1016","volume":"65","author":[{"given":"Karolin S.","family":"Hacker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katharina","family":"Jansson","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeanette","family":"Pichler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jawad","family":"Salman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Murat","family":"Avsar","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thierry","family":"Siemeni","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ann-Kathrin","family":"Kn\u00f6fel","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Klaus","family":"H\u00f6ffler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jens","family":"Gottlieb","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J\u00f6rg","family":"Fr\u00fchauf","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Martin","family":"Werner","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Reza","family":"Poyanmehr","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danny","family":"Jonigk","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael S.","family":"Balzer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marion","family":"Hewicker-Trautwein","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Axel","family":"Haverich","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wiebke","family":"Sommer","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gregor","family":"Warnecke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"6","key":"10.1016\/j.trim.2020.101350_bb0005","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a014985","article-title":"Why is organ transplantation clinically important?","volume":"3","author":"Grinyo","year":"2013","journal-title":"Cold Spring Harb. Perspect. Med."},{"issue":"8","key":"10.1016\/j.trim.2020.101350_bb0010","first-page":"1039","article-title":"Immunosuppression in lung transplantation","volume":"6","author":"Scheffert","year":"2014","journal-title":"J. Thorac. Dis."},{"issue":"5","key":"10.1016\/j.trim.2020.101350_bb0015","doi-asserted-by":"crossref","first-page":"461","DOI":"10.1016\/j.healun.2014.03.002","article-title":"Long-term immunosuppression and malignancy in thoracic transplantation: where is the balance?","volume":"33","author":"Nair","year":"2014","journal-title":"J. Heart Lung Transplant."},{"issue":"6","key":"10.1016\/j.trim.2020.101350_bb0020","doi-asserted-by":"crossref","first-page":"846","DOI":"10.1016\/j.ejcts.2006.09.027","article-title":"Bronchiolitis obliterans following lung transplantation","volume":"30","author":"Al-Githmi","year":"2006","journal-title":"Eur. J. Cardiothorac. Surg."},{"key":"10.1016\/j.trim.2020.101350_bb0025","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1146\/annurev.med.52.1.185","article-title":"Lung transplantation at the turn of the century","volume":"52","author":"DeMeo","year":"2001","journal-title":"Annu. Rev. Med."},{"issue":"5","key":"10.1016\/j.trim.2020.101350_bb0030","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1111\/ajt.13629","article-title":"Augmentation of transient donor cell chimerism and alloantigen-specific regulation of lung transplants in miniature swine","volume":"16","author":"Avsar","year":"2016","journal-title":"Am. J. Transplant."},{"issue":"1","key":"10.1016\/j.trim.2020.101350_bb0035","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/01.tp.0000225833.23093.ed","article-title":"Preoperative low-dose irradiation promotes long-term allograft acceptance and induces regulatory T cells in a porcine model of pulmonary transplantation","volume":"82","author":"Warnecke","year":"2006","journal-title":"Transplantation"},{"issue":"7","key":"10.1016\/j.trim.2020.101350_bb0040","article-title":"Splenocyte infusion and whole-body irradiation for induction of peripheral tolerance in porcine lung transplantation: modifications of the preconditioning regime for improved clinical feasibility","volume":"3","author":"Jansson","year":"2017","journal-title":"Transplant. Direct"},{"issue":"1","key":"10.1016\/j.trim.2020.101350_bb0045","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1067\/mtc.2002.119063","article-title":"Surfactant function in lung transplantation after 24 hours of ischemia: advantage of retrograde flush perfusion for preservation","volume":"123","author":"Struber","year":"2002","journal-title":"J. Thorac. Cardiovasc. Surg."},{"issue":"4","key":"10.1016\/j.trim.2020.101350_bb0050","doi-asserted-by":"crossref","first-page":"420","DOI":"10.1111\/tri.12916","article-title":"Irradiation before and donor splenocyte infusion immediately after transplantation induce tolerance to lung, but not heart allografts in miniature swine","volume":"30","author":"Sommer","year":"2017","journal-title":"Transpl. Int."},{"issue":"3 Pt 2","key":"10.1016\/j.trim.2020.101350_bb0055","doi-asserted-by":"crossref","first-page":"345","DOI":"10.1111\/j.1399-0012.1994.tb00267.x","article-title":"International standardization of criteria for histologic diagnosis of chronic rejection in renal allografts","volume":"8","author":"Solez","year":"1994","journal-title":"Clin. Transpl."},{"issue":"4","key":"10.1016\/j.trim.2020.101350_bb0060","doi-asserted-by":"crossref","first-page":"753","DOI":"10.1111\/j.1600-6143.2008.02159.x","article-title":"Banff 07 classification of renal allograft pathology: updates and future directions","volume":"8","author":"Solez","year":"2008","journal-title":"Am. J. Transplant."},{"issue":"10","key":"10.1016\/j.trim.2020.101350_bb0065","doi-asserted-by":"crossref","first-page":"1009","DOI":"10.1016\/j.healun.2014.08.004","article-title":"The registry of the International Society for Heart and Lung Transplantation: thirty-first adult lung and heart-lung transplant report\u20142014; focus theme: retransplantation","volume":"33","author":"Yusen","year":"2014","journal-title":"J. Heart Lung Transplant."},{"issue":"10","key":"10.1016\/j.trim.2020.101350_bb0070","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1097\/01.TP.0000128298.12937.B2","article-title":"Portal donor-specific blood transfusion and mycophenolate mofetil allow steroid avoidance and tacrolimus dose reduction with sustained levels of chimerism in a pig model of intestinal transplantation","volume":"77","author":"Gruessner","year":"2004","journal-title":"Transplantation"},{"issue":"3","key":"10.1016\/j.trim.2020.101350_bb0075","doi-asserted-by":"crossref","first-page":"332","DOI":"10.1111\/j.1432-2277.2008.00778.x","article-title":"Postoperative intravenous infusion of donor-derived transplant acceptance-inducing cells as an adjunct immunosuppressive therapy in a porcine pulmonary allograft model","volume":"22","author":"Warnecke","year":"2009","journal-title":"Transpl. Int."},{"issue":"1","key":"10.1016\/j.trim.2020.101350_bb0080","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1097\/01.tp.0000225833.23093.ed","article-title":"Preoperative low-dose irradiation promotes long-term allograft acceptance and induces regulatory T cells in a porcine model of pulmonary transplantation","volume":"82","author":"Warnecke","year":"2006","journal-title":"Transplantation"},{"issue":"10","key":"10.1016\/j.trim.2020.101350_bb0085","doi-asserted-by":"crossref","first-page":"1468","DOI":"10.1097\/TP.0b013e3181a3c4cb","article-title":"Correlation of donor leukocyte chimerism with pulmonary allograft survival after immunosuppressive drug withdrawal in a porcine model","volume":"87","author":"Kruse","year":"2009","journal-title":"Transplantation"},{"issue":"8","key":"10.1016\/j.trim.2020.101350_bb0090","doi-asserted-by":"crossref","first-page":"728","DOI":"10.1111\/j.1432-2277.2008.00680.x","article-title":"Transplant acceptance-inducing cells as an immune-conditioning therapy in renal transplantation","volume":"21","author":"Hutchinson","year":"2008","journal-title":"Transpl. Int."},{"issue":"9","key":"10.1016\/j.trim.2020.101350_bb0095","doi-asserted-by":"crossref","first-page":"1168","DOI":"10.1097\/01.tp.0000287335.25361.a2","article-title":"Splenocytes can replace chimeric cells and maintain allograft tolerance","volume":"84","author":"Hayashi","year":"2007","journal-title":"Transplantation"},{"issue":"6","key":"10.1016\/j.trim.2020.101350_bb0100","doi-asserted-by":"crossref","first-page":"855","DOI":"10.1097\/00007890-199909270-00019","article-title":"In vivo T cell depletion in miniature swine using the swine CD3 immunotoxin, pCD3-CRM9","volume":"68","author":"Huang","year":"1999","journal-title":"Transplantation"},{"issue":"2","key":"10.1016\/j.trim.2020.101350_bb0105","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1172\/JCI7913","article-title":"Stable mixed chimerism and tolerance using a nonmyeloablative preparative regimen in a large-animal model","volume":"105","author":"Huang","year":"2000","journal-title":"J. Clin. Invest."},{"issue":"12","key":"10.1016\/j.trim.2020.101350_bb0110","doi-asserted-by":"crossref","first-page":"e140","DOI":"10.1097\/TP.0000000000001480","article-title":"Induction of major histocompatibility complex-mismatched mouse lung allograft acceptance with combined donor bone marrow: lung transplant using a 12-hour Nonmyeloablative conditioning regimen","volume":"100","author":"Dodd-O","year":"2016","journal-title":"Transplantation"}],"container-title":["Transplant Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966327420300654?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966327420300654?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T18:00:26Z","timestamp":1760810426000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0966327420300654"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,4]]},"references-count":22,"alternative-id":["S0966327420300654"],"URL":"https:\/\/doi.org\/10.1016\/j.trim.2020.101350","relation":{},"ISSN":["0966-3274"],"issn-type":[{"type":"print","value":"0966-3274"}],"subject":[],"published":{"date-parts":[[2021,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Delayed non-myeloablative irradiation to induce long-term allograft acceptance in a large animal lung transplantation model","name":"articletitle","label":"Article Title"},{"value":"Transplant Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trim.2020.101350","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2020 Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"101350"}}