{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T13:53:55Z","timestamp":1793195635690,"version":"4.5.0"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,12,1]],"date-time":"2022-12-01T00:00:00Z","timestamp":1669852800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transplant Immunology"],"published-print":{"date-parts":[[2022,12]]},"DOI":"10.1016\/j.trim.2022.101715","type":"journal-article","created":{"date-parts":[[2022,9,17]],"date-time":"2022-09-17T09:13:15Z","timestamp":1663405995000},"page":"101715","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Identifying stable reference genes in polyethene glycol precipitated urinary extracellular vesicles for RT-qPCR-based gene expression studies in renal graft dysfunction patients"],"prefix":"10.1016","volume":"75","author":[{"given":"Anula Divyash","family":"Singh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sreekanth","family":"Patnam","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajeswari","family":"Koyyada","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rasmita","family":"Samal","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed Baseeruddin","family":"Alvi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"G.","family":"Satyanaryana","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ravi","family":"Andrews","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aswini Kumar","family":"Panigrahi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aravind Kumar","family":"Rengan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soma Sekhar","family":"Mudigonda","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Maitra","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Manda Venkata","family":"Sasidhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"5","key":"10.1016\/j.trim.2022.101715_bb0055","doi-asserted-by":"crossref","first-page":"1039","DOI":"10.1038\/ki.2013.512","article-title":"Utility of renal biopsy in the clinical management of renal disease","volume":"85","author":"Dhaun","year":"2014","journal-title":"Kidney Int."},{"issue":"11","key":"10.1016\/j.trim.2022.101715_bb0240","doi-asserted-by":"crossref","first-page":"3263","DOI":"10.1093\/ndt\/gfp428","article-title":"Creatinine as the gold standard for kidney injury biomarker studies?","volume":"24","author":"Waikar","year":"2009","journal-title":"Nephrol. Dial. Transplant."},{"issue":"8","key":"10.1016\/j.trim.2022.101715_bb0200","doi-asserted-by":"crossref","first-page":"2268","DOI":"10.1021\/bi00511a031","article-title":"Multiple ribonucleases of human urine","volume":"20","author":"Sugiyama","year":"1981","journal-title":"Biochemistry"},{"issue":"1","key":"10.1016\/j.trim.2022.101715_bb0015","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1007\/s00441-017-2621-0","article-title":"Urinary extracellular vesicles. A promising shortcut to novel biomarker discoveries","volume":"369","author":"Barreiro","year":"2017","journal-title":"Cell Tissue Res."},{"key":"10.1016\/j.trim.2022.101715_bb0160","doi-asserted-by":"crossref","first-page":"27494","DOI":"10.3402\/jev.v4.27494","article-title":"Biogenesis, delivery, and function of extracellular RNA","volume":"4","author":"Patton","year":"2015","journal-title":"J. Extracell Vesicles"},{"key":"10.1016\/j.trim.2022.101715_bb0100","doi-asserted-by":"crossref","first-page":"7844455","DOI":"10.1155\/2021\/7844455","article-title":"Exosomes: emerging therapy delivery tools and biomarkers for kidney diseases","volume":"2021","author":"Jin","year":"2021","journal-title":"Stem Cells Int."},{"key":"10.1016\/j.trim.2022.101715_bb0220","doi-asserted-by":"crossref","first-page":"1655","DOI":"10.3389\/fphar.2019.01655","article-title":"Roles for exosome in various kidney diseases and disorders","volume":"10","author":"Thongboonkerd","year":"2019","journal-title":"Front. Pharmacol."},{"issue":"9","key":"10.1016\/j.trim.2022.101715_bb0110","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1038\/nrneph.2017.98","article-title":"Extracellular vesicles in renal disease","volume":"13","author":"Karpman","year":"2017","journal-title":"Nat. Rev. Nephrol."},{"issue":"12","key":"10.1016\/j.trim.2022.101715_bb0040","doi-asserted-by":"crossref","DOI":"10.3390\/ijms22126507","article-title":"Urinary extracellular vesicles: uncovering the basis of the pathological processes in kidney-related diseases","volume":"22","author":"Cricr\u00ec","year":"2021","journal-title":"Int. J. Mol. Sci."},{"issue":"2","key":"10.1016\/j.trim.2022.101715_bb0135","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1111\/jcmm.14101","article-title":"New insight into the role of extracellular vesicles in kidney disease","volume":"23","author":"Lv","year":"2019","journal-title":"J. Cell. Mol. Med."},{"issue":"1","key":"10.1016\/j.trim.2022.101715_bb0085","doi-asserted-by":"crossref","first-page":"237","DOI":"10.7150\/thno.21945","article-title":"Exosome theranostics: biology and translational medicine","volume":"8","author":"He","year":"2018","journal-title":"Theranostics"},{"issue":"5","key":"10.1016\/j.trim.2022.101715_bb0205","article-title":"Urinary extracellular vesicles as biomarkers of kidney disease: from diagnostics to therapeutics","volume":"10","author":"Sun","year":"2020","journal-title":"Diagnostics (Basel)"},{"key":"10.1016\/j.trim.2022.101715_bb0265","series-title":"Urine Analysis has a Very Broad Prospect in the Future","volume":"1","author":"Zhang","year":"2022"},{"key":"10.1016\/j.trim.2022.101715_bb0105","article-title":"A modified precipitation method to isolate urinary exosomes","volume":"95","author":"Kanchi Ravi","year":"2015","journal-title":"J. Vis. Exp."},{"key":"10.1016\/j.trim.2022.101715_bb0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.bdq.2019.100089","article-title":"Comparing small urinary extracellular vesicle purification methods with a view to RNA sequencing-enabling robust and non-invasive biomarker research","volume":"17","author":"Mussack","year":"2019","journal-title":"Biomol. Detect Quantif."},{"key":"10.1016\/j.trim.2022.101715_bb0230","series-title":"Methods for Exosome Isolation. International Search report (Art.21(3)). E. P. SPECIFICATION","author":"Vlassov","year":"2013"},{"issue":"4","key":"10.1016\/j.trim.2022.101715_bb0260","doi-asserted-by":"crossref","first-page":"319","DOI":"10.1101\/pdb.top074476","article-title":"Strategies for isolation of exosomes","volume":"2015","author":"Zeringer","year":"2015","journal-title":"Cold Spring Harb Protoc"},{"issue":"5","key":"10.1016\/j.trim.2022.101715_bb0130","doi-asserted-by":"crossref","first-page":"973","DOI":"10.1007\/s11255-017-1779-4","article-title":"A PEG-based method for the isolation of urinary exosomes and its application in renal fibrosis diagnostics using cargo miR-29c and miR-21 analysis","volume":"50","author":"Lv","year":"2018","journal-title":"Int. Urol. Nephrol."},{"issue":"8","key":"10.1016\/j.trim.2022.101715_bb0255","first-page":"1657","article-title":"Effective enrichment of urinary exosomes by polyethylene glycol for RNA detection","volume":"29","author":"Yang","year":"2018","journal-title":"Biomed. Res."},{"key":"10.1016\/j.trim.2022.101715_bb0185","doi-asserted-by":"crossref","first-page":"66","DOI":"10.3389\/fmolb.2017.00066","article-title":"Asymmetric RNA distribution among cells and their secreted exosomes: biomedical meaning and considerations on diagnostic applications","volume":"4","author":"Ragusa","year":"2017","journal-title":"Front. Mol. Biosci."},{"key":"10.1016\/j.trim.2022.101715_bb0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.bdq.2019.100090","article-title":"For what factors should we normalize urinary extracellular mRNA biomarkers?","volume":"17","author":"Gunasekaran","year":"2019","journal-title":"Biomol. Detect Quantif."},{"issue":"4","key":"10.1016\/j.trim.2022.101715_bb0020","doi-asserted-by":"crossref","first-page":"217","DOI":"10.1016\/j.ymeth.2009.12.006","article-title":"Why the need for qPCR publication guidelines?--The case for MIQE","volume":"50","author":"Bustin","year":"2010","journal-title":"Methods"},{"issue":"9","key":"10.1016\/j.trim.2022.101715_bb0045","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0000898","article-title":"Evidence based selection of housekeeping genes","volume":"2","author":"de Jonge","year":"2007","journal-title":"PLoS One"},{"key":"10.1016\/j.trim.2022.101715_bb0060","doi-asserted-by":"crossref","first-page":"42427","DOI":"10.1038\/srep42427","article-title":"Appropriateness of reference genes for normalizing messenger RNA in mouse 2,4-dinitrobenzene sulfonic acid (DNBS)-induced colitis using quantitative real time PCR","volume":"7","author":"Eissa","year":"2017","journal-title":"Sci. Rep."},{"key":"10.1016\/j.trim.2022.101715_bb0245","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1186\/1744-8069-10-55","article-title":"Validation of four reference genes for quantitative mRNA expression studies in a rat model of inflammatory injury","volume":"10","author":"Walder","year":"2014","journal-title":"Mol. Pain"},{"issue":"1","key":"10.1016\/j.trim.2022.101715_bb0165","first-page":"3612","article-title":"Validation of optimal reference genes for quantitative real time PCR in muscle and adipose tissue for obesity and diabetes research","volume":"7","author":"Perez","year":"2017"},{"issue":"15","key":"10.1016\/j.trim.2022.101715_bb0010","doi-asserted-by":"crossref","first-page":"5245","DOI":"10.1158\/0008-5472.CAN-04-0496","article-title":"Normalization of real-time quantitative reverse transcription-PCR data: a model-based variance estimation approach to identify genes suited for normalization, applied to bladder and colon cancer data sets","volume":"64","author":"Andersen","year":"2004","journal-title":"Cancer Res."},{"issue":"7","key":"10.1016\/j.trim.2022.101715_bb0225","doi-asserted-by":"crossref","DOI":"10.1186\/gb-2002-3-7-research0034","article-title":"Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes","volume":"3","author":"Vandesompele","year":"2002","journal-title":"Genome Biol."},{"issue":"6","key":"10.1016\/j.trim.2022.101715_bb0170","doi-asserted-by":"crossref","first-page":"509","DOI":"10.1023\/B:BILE.0000019559.84305.47","article-title":"Determination of stable housekeeping genes, differentially regulated target genes and sample integrity: BestKeeper--Excel-based tool using pair-wise correlations","volume":"26","author":"Pfaffl","year":"2004","journal-title":"Biotechnol. Lett."},{"key":"10.1016\/j.trim.2022.101715_bb0195","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1186\/1471-2199-7-33","article-title":"Selection of housekeeping genes for gene expression studies in human reticulocytes using real-time PCR","volume":"7","author":"Silver","year":"2006","journal-title":"BMC Mol. Biol."},{"key":"10.1016\/j.trim.2022.101715_bb0250","doi-asserted-by":"crossref","DOI":"10.1007\/s11103-012-9885-2","article-title":"miRDeepFinder: a miRNA analysis tool for deep sequencing of plant small RNAs","author":"Xie","year":"2012","journal-title":"Plant Mol. Biol."},{"issue":"6","key":"10.1016\/j.trim.2022.101715_bb0140","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1016\/j.eururo.2018.08.019","article-title":"A prospective adaptive utility trial to validate performance of a novel urine exosome gene expression assay to predict high-grade prostate cancer in patients with prostate-specific antigen 2-10ng\/ml at initial biopsy","volume":"74","author":"McKiernan","year":"2018","journal-title":"Eur. Urol."},{"issue":"2","key":"10.1016\/j.trim.2022.101715_bb0030","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0017347","article-title":"Identification of reference genes across physiological states for qRT-PCR through microarray meta-analysis","volume":"6","author":"Cheng","year":"2011","journal-title":"PLoS One"},{"issue":"15","key":"10.1016\/j.trim.2022.101715_bb0180","doi-asserted-by":"crossref","DOI":"10.3390\/ijms21155404","article-title":"Recent advances on biomarkers of early and late kidney graft dysfunction","volume":"21","author":"Quaglia","year":"2020","journal-title":"Int. J. Mol. Sci."},{"issue":"1","key":"10.1016\/j.trim.2022.101715_bb0155","doi-asserted-by":"crossref","first-page":"109","DOI":"10.5114\/ceji.2014.42135","article-title":"Perforin: an important player in immune response","volume":"39","author":"Osi\u0144ska","year":"2014","journal-title":"Cent. Eur. J. Immunol."},{"issue":"6","key":"10.1016\/j.trim.2022.101715_bb0235","doi-asserted-by":"crossref","first-page":"388","DOI":"10.1038\/nri3839","article-title":"Perforin and granzymes: function, dysfunction and human pathology","volume":"15","author":"Voskoboinik","year":"2015","journal-title":"Nat. Rev. Immunol."},{"issue":"7","key":"10.1016\/j.trim.2022.101715_bb0065","doi-asserted-by":"crossref","DOI":"10.1002\/jev2.12093","article-title":"Urinary extracellular vesicles: a position paper by the urine task force of the international society for extracellular vesicles","volume":"10","author":"Erdbr\u00fcgger","year":"2021","journal-title":"J. Extracell Vesicles"},{"issue":"1","key":"10.1016\/j.trim.2022.101715_bb0270","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1007\/s11255-016-1408-7","article-title":"Effect of pH on the isolation of urinary exosome","volume":"49","author":"Zhao","year":"2017","journal-title":"Int. Urol. Nephrol."},{"issue":"4","key":"10.1016\/j.trim.2022.101715_bb0210","doi-asserted-by":"crossref","first-page":"4857","DOI":"10.1007\/s11033-011-1281-5","article-title":"Identification of valid housekeeping genes for quantitative RT-PCR analysis of cardiosphere-derived cells preconditioned under hypoxia or with prolyl-4-hydroxylase inhibitors","volume":"39","author":"Tan","year":"2012","journal-title":"Mol. Biol. Rep."},{"issue":"1","key":"10.1016\/j.trim.2022.101715_bb0190","doi-asserted-by":"crossref","first-page":"4","DOI":"10.1186\/s12865-020-0334-8","article-title":"Reliable reference genes for the quantification of mRNA in human T-cells and PBMCs stimulated with live influenza virus","volume":"21","author":"Roy","year":"2020","journal-title":"BMC Immunol."},{"issue":"8","key":"10.1016\/j.trim.2022.101715_bb0070","doi-asserted-by":"crossref","first-page":"736","DOI":"10.1038\/ki.2009.550","article-title":"Tamm-Horsfall protein and urinary exosome isolation","volume":"77","author":"Fern\u00e1ndez-Llama","year":"2010","journal-title":"Kidney Int."},{"key":"10.1016\/j.trim.2022.101715_bb0125","doi-asserted-by":"crossref","first-page":"26913","DOI":"10.3402\/jev.v3.26913","article-title":"Minimal experimental requirements for definition of extracellular vesicles and their functions: a position statement from the International Society for Extracellular Vesicles","volume":"3","author":"L\u00f6tvall","year":"2014","journal-title":"J. Extracell Vesicles"},{"issue":"1","key":"10.1016\/j.trim.2022.101715_bb0215","doi-asserted-by":"crossref","first-page":"1535750","DOI":"10.1080\/20013078.2018.1535750","article-title":"Minimal information for studies of extracellular vesicles 2018 (MISEV2018): a position statement of the International Society for Extracellular Vesicles and update of the MISEV2014 guidelines","volume":"7","author":"Th\u00e9ry","year":"2018","journal-title":"J. Extracell Vesicles"},{"issue":"1","key":"10.1016\/j.trim.2022.101715_bb0075","doi-asserted-by":"crossref","first-page":"3945","DOI":"10.1038\/s41598-018-22142-x","article-title":"Improved isolation strategies to increase the yield and purity of human urinary exosomes for biomarker discovery","volume":"8","author":"Gheinani","year":"2018","journal-title":"Sci. Rep."},{"issue":"9","key":"10.1016\/j.trim.2022.101715_bb0005","doi-asserted-by":"crossref","first-page":"1024","DOI":"10.1038\/ki.2012.256","article-title":"Comparison of protein, microRNA, and mRNA yields using different methods of urinary exosome isolation for the discovery of kidney disease biomarkers","volume":"82","author":"Alvarez","year":"2012","journal-title":"Kidney Int."},{"issue":"36","key":"10.1016\/j.trim.2022.101715_bb0175","doi-asserted-by":"crossref","first-page":"13368","DOI":"10.1073\/pnas.0403453101","article-title":"Identification and proteomic profiling of exosomes in human urine","volume":"101","author":"Pisitkun","year":"2004","journal-title":"Proc. Natl. Acad. Sci. U. S. A."},{"issue":"1652","key":"10.1016\/j.trim.2022.101715_bb0120","article-title":"Analysis of the RNA content of the exosomes derived from blood serum and urine and its potential as biomarkers","volume":"369","author":"Li","year":"2014","journal-title":"Philos. Trans. R. Soc. Lond. Ser. B Biol. Sci."},{"issue":"12","key":"10.1016\/j.trim.2022.101715_bb0145","doi-asserted-by":"crossref","first-page":"731","DOI":"10.1038\/nrneph.2017.148","article-title":"Isolation and characterization of urinary extracellular vesicles: implications for biomarker discovery","volume":"13","author":"Merchant","year":"2017","journal-title":"Nat. Rev. Nephrol."},{"issue":"4","key":"10.1016\/j.trim.2022.101715_bb0025","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1373\/clinchem.2008.112797","article-title":"The MIQE guidelines: minimum information for publication of quantitative real-time PCR experiments","volume":"55","author":"Bustin","year":"2009","journal-title":"Clin. Chem."},{"issue":"3","key":"10.1016\/j.trim.2022.101715_bb0050","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0122515","article-title":"Reference gene validation for RT-qPCR, a note on different available software packages","volume":"10","author":"De Spiegelaere","year":"2015","journal-title":"PLoS One"},{"key":"10.1016\/j.trim.2022.101715_bb0090","doi-asserted-by":"crossref","first-page":"2055","DOI":"10.3389\/fmicb.2019.02055","article-title":"Validation of reliable reference genes for RT-qPCR studies of target gene expression in colletotrichum camelliae during spore germination and mycelial growth and interaction with host plants","volume":"10","author":"He","year":"2019","journal-title":"Front. Microbiol."},{"issue":"1","key":"10.1016\/j.trim.2022.101715_bb0095","doi-asserted-by":"crossref","first-page":"3203","DOI":"10.1038\/s41598-018-21374-1","article-title":"Validation of house-keeping genes for normalization of gene expression data during diurnal\/circadian studies in rice by RT-qPCR","volume":"8","author":"Jain","year":"2018","journal-title":"Sci. Rep."},{"issue":"4","key":"10.1016\/j.trim.2022.101715_bb0035","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1038\/cdd.2009.161","article-title":"Granzymes and perforin in solid organ transplant rejection","volume":"17","author":"Choy","year":"2010","journal-title":"Cell Death Differ."},{"issue":"13","key":"10.1016\/j.trim.2022.101715_bb0115","doi-asserted-by":"crossref","first-page":"947","DOI":"10.1056\/NEJM200103293441301","article-title":"Noninvasive diagnosis of renal-allograft rejection by measurement of messenger RNA for perforin and granzyme B in urine","volume":"344","author":"Li","year":"2001","journal-title":"N. Engl. J. Med."}],"container-title":["Transplant Immunology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966327422001897?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0966327422001897?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,18]],"date-time":"2025-10-18T18:02:00Z","timestamp":1760810520000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0966327422001897"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,12]]},"references-count":54,"alternative-id":["S0966327422001897"],"URL":"https:\/\/doi.org\/10.1016\/j.trim.2022.101715","relation":{},"ISSN":["0966-3274"],"issn-type":[{"value":"0966-3274","type":"print"}],"subject":[],"published":{"date-parts":[[2022,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identifying stable reference genes in polyethene glycol precipitated urinary extracellular vesicles for RT-qPCR-based gene expression studies in renal graft dysfunction patients","name":"articletitle","label":"Article Title"},{"value":"Transplant Immunology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trim.2022.101715","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"101715"}}