{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,28]],"date-time":"2026-01-28T21:42:30Z","timestamp":1769636550001,"version":"3.49.0"},"reference-count":38,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2004,11,1]],"date-time":"2004-11-01T00:00:00Z","timestamp":1099267200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology"],"published-print":{"date-parts":[[2004,11]]},"DOI":"10.1016\/j.tripleo.2004.02.057","type":"journal-article","created":{"date-parts":[[2004,11,6]],"date-time":"2004-11-06T18:01:23Z","timestamp":1099764083000},"page":"533-540","source":"Crossref","is-referenced-by-count":41,"title":["Relationship of calcitonin gene-related peptide in synovial tissues and temporomandibular joint pain in humans"],"prefix":"10.1016","volume":"98","author":[{"given":"Jun","family":"Sato","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natsuki","family":"Segami","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Keiseki","family":"Kaneyama","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroshi","family":"Yoshimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazuma","family":"Fujimura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshino","family":"Yoshitake","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tripleo.2004.02.057_BIB1","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0278-2391(98)90867-9","article-title":"The influence of neuropeptides, serotonin, and interleukin 1\u03b2 on temporomandibular joint pain and inflammation","volume":"56","author":"Kopp","year":"1998","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB2","doi-asserted-by":"crossref","first-page":"1159","DOI":"10.1016\/0278-2391(91)90407-D","article-title":"Correlation between pain and synovitis in patients with internal derangement of the temporomandibular joint","volume":"49","author":"Murakami","year":"1991","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB3","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/S0901-5027(88)80227-3","article-title":"Arthroscopy of the temporomandibular joint: occurrence and location of osteoarthrosis and synovitis in a patient material","volume":"17","author":"Holmlund","year":"1988","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB4","doi-asserted-by":"crossref","first-page":"1187","DOI":"10.1016\/S0278-2391(99)90483-4","article-title":"Relationship between joint effusion, joint pain, and protein levels in joint lavage fluid of patients with internal derangement and osteoarthritis of the temporomandibular joint","volume":"57","author":"Takahashi","year":"1999","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB5","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/0278-2391(94)90217-8","article-title":"Tumor necrosis factor\" as a biochemical marker of pain and outcome in temporomandibular joints with internal derangements","volume":"52","author":"Shaefr","year":"1994","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB6","first-page":"131","article-title":"Interleukin-6 in synovial fluid and HLA-DR expression in synovium from patients with temporomandibular disorders","volume":"9","author":"Fu","year":"1995","journal-title":"J Orofac Pain"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB7","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/S1079-2104(98)90415-2","article-title":"Proinflammatory cytokines detectable in synovial fluids from patients with temporomandibular disorders","volume":"85","author":"Takahashi","year":"1998","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB8","doi-asserted-by":"crossref","first-page":"413","DOI":"10.1016\/S1079-2104(99)70054-5","article-title":"Specific expression of interleukin 1\u03b2 in temporomandibular joints with internal derangement: correlation with clinical findings","volume":"88","author":"Suzuki","year":"1999","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB9","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1016\/0278-2391(90)90011-P","article-title":"Identification of prostaglandin E2 and leukotrien B4 in the synovial fluid of painful, dysfunctional temporomandibular joints","volume":"48","author":"Quinn","year":"1990","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB10","doi-asserted-by":"crossref","first-page":"68","DOI":"10.1054\/bjom.2001.0742","article-title":"Proinflammatory cytokines and arthroscopic findings of patients with internal derangement and osteoarthritis of the temporomandibular joint","volume":"40","author":"Nishimura","year":"2002","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB11","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1016\/S0901-5027(05)80181-X","article-title":"Concentrations of neuropeptides substance P, Neurokinin A, calcitonin gene-related peptide, neuropeptide Y and vasoactive intestinal polypeptide in synovial fluid of the human temporomandibular joint","volume":"20","author":"Holmlund","year":"1991","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB12","doi-asserted-by":"crossref","first-page":"384","DOI":"10.1067\/moe.2001.117811","article-title":"Substance P and mast cells: preliminary histologic analysis of the human temporomandibular joint","volume":"92","author":"Henry","year":"2001","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB13","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/0196-9781(91)90022-H","article-title":"Calcitonin gene-related peptide, neurokinin A and substance P: effects on nociception and neurogenic inflammation in human skin and temporal muscle","volume":"12","author":"Pedersen-Bjergaard","year":"1991","journal-title":"PEPTIDES"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB14","doi-asserted-by":"crossref","first-page":"129","DOI":"10.1038\/304129a0","article-title":"Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA-processing","volume":"304","author":"Rosenfeld","year":"1983","journal-title":"Nature"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB15","doi-asserted-by":"crossref","first-page":"199","DOI":"10.1016\/0304-3940(84)90374-4","article-title":"Immunoreactive calcitonin gene-related peptide and substance P coexist in sensory neurons to the spinal cord and interact in spinal behavioral response of the rat","volume":"52","author":"Wiesenfeld-Hallin","year":"1984","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB16","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0304-3940(98)00210-9","article-title":"Changes in neuropeptide immunoreactivity in cultured adult mouse sensory neurons following methylmercury chloride treatments","volume":"246","author":"Baxter","year":"1988","journal-title":"Neurosci Lett"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB17","doi-asserted-by":"crossref","first-page":"2481","DOI":"10.1002\/1097-0142(19851115)56:10<2481::AID-CNCR2820561026>3.0.CO;2-Y","article-title":"Medullary carcinoma of the thyroid. An immuocytochemical and histochemical study of 25 cases using eight separate makers","volume":"56","author":"Sikri","year":"1985","journal-title":"Cancer"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB18","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1007\/BF01951817","article-title":"Peptidergic innervation of the temporomandibular disk in the rat","volume":"45","author":"Ichikawa","year":"1989","journal-title":"Experentia"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB19","doi-asserted-by":"crossref","first-page":"592","DOI":"10.1177\/00220345930720030701","article-title":"Distribution of substance P and calcitonin gene-related peptide-like immunoreactive nerve fibers in the rat temporomandibular joint","volume":"72","author":"Kido","year":"1993","journal-title":"J Dent Res"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB20","doi-asserted-by":"crossref","first-page":"568","DOI":"10.1002\/(SICI)1097-0185(199607)245:3<568::AID-AR13>3.0.CO;2-N","article-title":"Postnatal development of protein gene product 9.5- and calcitonin gene-related peptide-like immunoreactive nerve fibers in the rat temporomandibular joint","volume":"245","author":"Shimiz","year":"1996","journal-title":"Anat Rec"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB21","first-page":"215","article-title":"Neuropeptides in the arthritic TMJ and symptoms and signs from the stomatognathic system with special consideration to rheumatoid arthritis","volume":"9","author":"Appelgren","year":"1995","journal-title":"J Orofacial Pain"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB22","doi-asserted-by":"crossref","first-page":"390","DOI":"10.1054\/jcms.2000.0086","article-title":"Arthroscopic eminoplasty for habitual dislocation of the temporomandibular joint: preliminary study","volume":"27","author":"Segami","year":"1999","journal-title":"J Craniomaxillofac Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB23","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1067\/moe.2002.122161","article-title":"The expression of vascular endothelial growth factor in synovial tissues in patients with internal derangement of the temporomandibular joint","volume":"93","author":"Sato","year":"2002","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB24","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1016\/S0266-4356(02)00294-2","article-title":"Expression of interleukin 6 in synovial tissues in patients with internal derangement of the temporomandibular Joint","volume":"41","author":"Sato","year":"2003","journal-title":"Br J Oral Maxillofacial Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB25","doi-asserted-by":"crossref","first-page":"272","DOI":"10.1177\/154405910308200406","article-title":"Correlation of the expression of fibroblast growth factor-2, vascular endothelial growth factor, and their receptors with angiogenesis in synovial tissues from patients with internal derangement of the temporomandibular joint","volume":"82","author":"Sato","year":"2003","journal-title":"J Dent Res"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB26","first-page":"401","article-title":"Tumor angiogenesis correlates with metastasis in invasive prostate carcinoma","volume":"143","author":"Weidner","year":"1993","journal-title":"Am J Pathol"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB27","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1002\/(SICI)1096-9896(199908)188:4<369::AID-PATH381>3.0.CO;2-X","article-title":"Expression of vascular endothelial growth factor (VEGF) and its two receptors (VEGF-R1-Flt1 and VEGF-R2-Flk1\/KDR) in non-small cell lung carcinoma (NSCLCs): correlation with angiogenesis and survival","volume":"188","author":"Decaussin","year":"1999","journal-title":"J Pathol"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB28","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/0749-8063(91)90111-A","article-title":"Puncture technique and portals of entry for diagnostic and operative arthroscopy of the temporomandibular joint","volume":"7","author":"McCain","year":"1991","journal-title":"Arthroscopy"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB29","first-page":"519","article-title":"Neuropeptides in temporomandibular joints with rheumatoid arthritis: a clinical study","volume":"99","author":"Appelgren","year":"1991","journal-title":"Scand J Dent Res"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB30","first-page":"36","article-title":"Innervation of the human temporomandibular joint capsule and disc as revealed by immunohistochemistry for neurospecific markers","volume":"8","author":"Morani","year":"1994","journal-title":"J Orofacial Pain"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB31","doi-asserted-by":"crossref","first-page":"16","DOI":"10.1002\/aja.1001820103","article-title":"Mechanoreceptors in articular tissues","volume":"182","author":"Zimny","year":"1988","journal-title":"Am J Anat"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB32","first-page":"225","article-title":"Distribution of substance P-like immunoreactive nerve fibers in temporomandibular joint soft tissues of monkey","volume":"94","author":"Johansson","year":"1986","journal-title":"Scand J Dent Res"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB33","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/0278-2391(92)90391-C","article-title":"Neural elements in the human temporomandibular articular disc","volume":"50","author":"Wink","year":"1992","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB34","first-page":"8","article-title":"Innervation of temporomandibular joint capsule in man","volume":"2","author":"Thilander","year":"1961","journal-title":"Trans R Sch Dent (Stockholm)"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB35","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1038\/313054a0","article-title":"Calcitonin gene related peptide is a potent vasodilator","volume":"313","author":"Brain","year":"1986","journal-title":"Nature"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB36","doi-asserted-by":"crossref","first-page":"559","DOI":"10.2214\/ajr.159.3.1503025","article-title":"Temporomandibular joint relationship between MR evidence of effusion and the presence of pain and disc displacement","volume":"159","author":"Westesson","year":"1992","journal-title":"AJR"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB37","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1016\/S0278-2391(00)90141-1","article-title":"The association of temporomandibular joint pain with abnormal bone marrow in the mandibular condyle","volume":"58","author":"Sano","year":"2000","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2004.02.057_BIB38","doi-asserted-by":"crossref","first-page":"673","DOI":"10.1016\/j.tripleo.2003.08.016","article-title":"Levels of fibroblast growth factor-2 in synovial fluids in human patients with internal derangement of the temporomandibular joint","volume":"96","author":"Sato","year":"2003","journal-title":"Oral Surg Oral Pathol Oral Radiol Endod"}],"container-title":["Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079210404001581?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079210404001581?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,2,2]],"date-time":"2019-02-02T08:55:48Z","timestamp":1549097748000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079210404001581"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2004,11]]},"references-count":38,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2004,11]]}},"alternative-id":["S1079210404001581"],"URL":"https:\/\/doi.org\/10.1016\/j.tripleo.2004.02.057","relation":{},"ISSN":["1079-2104"],"issn-type":[{"value":"1079-2104","type":"print"}],"subject":[],"published":{"date-parts":[[2004,11]]}}}