{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,21]],"date-time":"2026-07-21T15:24:07Z","timestamp":1784647447009,"version":"3.55.0"},"reference-count":27,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2007,5,1]],"date-time":"2007-05-01T00:00:00Z","timestamp":1177977600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology"],"published-print":{"date-parts":[[2007,5]]},"DOI":"10.1016\/j.tripleo.2006.11.033","type":"journal-article","created":{"date-parts":[[2007,2,28]],"date-time":"2007-02-28T07:31:22Z","timestamp":1172647882000},"page":"e16-e20","source":"Crossref","is-referenced-by-count":59,"title":["Comparison of topical anesthetics (EMLA\/Oraqix vs. benzocaine) on pain experienced during palatal needle injection"],"prefix":"10.1016","volume":"103","author":[{"given":"Manal Abu","family":"Al-Melh","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lars","family":"Andersson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tripleo.2006.11.033_bib1","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1067\/moe.2002.124858","article-title":"Comparison of topical anesthesia of 20% benzocaine and 60% lidocaine gel","volume":"94","author":"Fukayama","year":"2002","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.tripleo.2006.11.033_bib2","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1038\/sj.bdj.4800999","article-title":"A randomized, double-blinded, placebo-controlled, comparative study of topical skin analgesics and the anxiety and discomfort associated with venous cannulation","volume":"190","author":"Speirs","year":"2001","journal-title":"Br Dent J"},{"key":"10.1016\/j.tripleo.2006.11.033_bib3","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1177\/000348940211100113","article-title":"Local anesthesia with EMLA cream for maxillary sinus puncture","volume":"111","author":"Joki-Erkkil\u00e4","year":"2002","journal-title":"Ann Otol Rhinol Laryngol"},{"key":"10.1016\/j.tripleo.2006.11.033_bib4","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/00006254-200203000-00022","article-title":"Topical anesthesia for minor gynecological procedures: a review","volume":"57","author":"Zilbert","year":"2002","journal-title":"Obstet Gynecol Surv"},{"key":"10.1016\/j.tripleo.2006.11.033_bib5","doi-asserted-by":"crossref","first-page":"58","DOI":"10.1054\/bjom.1999.0143","article-title":"The efficacy of Emla and 5% lignocaine for anaesthesia of human gingival mucosa","volume":"38","author":"McMillan","year":"2000","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2006.11.033_bib6","doi-asserted-by":"crossref","first-page":"425","DOI":"10.1034\/j.1600-051x.2001.028005425.x","article-title":"Plasma levels of lidocaine and prilocaine after application of Oraqix, a new intrapocket anaesthetic, in patients with advanced periodontitis","volume":"28","author":"Friskopp","year":"2001","journal-title":"J Clin Periodontal"},{"key":"10.1016\/j.tripleo.2006.11.033_bib7","doi-asserted-by":"crossref","first-page":"453","DOI":"10.1034\/j.1600-051x.2001.028005453.x","article-title":"The anesthetic onset and duration of a new lidocaine\/prilocaine gel intra-pocket anaesthetic (Oraqix) for periodontal scaling\/root planing","volume":"28","author":"Friskopp","year":"2001","journal-title":"J Clin Periodontal"},{"key":"10.1016\/j.tripleo.2006.11.033_bib8","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1902\/jop.2001.72.7.895","article-title":"Intrapocket anesthesia for scaling and root planing: results of a double-blind multicenter trial using lidocaine prilocaine dental gel","volume":"72","author":"Jeffcoat","year":"2001","journal-title":"J Periodontal"},{"key":"10.1016\/j.tripleo.2006.11.033_bib9","doi-asserted-by":"crossref","first-page":"215","DOI":"10.17796\/jcpd.25.3.hn62713500418728","article-title":"Use of EMLA: is it an injection free alternative?","volume":"25","author":"Munshi","year":"2001","journal-title":"J Clin Pediatr Dent"},{"key":"10.1016\/j.tripleo.2006.11.033_bib10","first-page":"1","article-title":"Reduction of pain from needle stick in the oral mucosa by topical anesthetics: a comparative study between lidocaine\/prilocaine and benzocaine","volume":"16","author":"Al-Melh","year":"2005","journal-title":"J Clin Dent"},{"key":"10.1016\/j.tripleo.2006.11.033_bib11","doi-asserted-by":"crossref","first-page":"759","DOI":"10.1016\/S0011-8532(02)00035-6","article-title":"Effective Topical anesthetic agents and techniques","volume":"46","author":"Meechan","year":"2002","journal-title":"Dent Clin N Am"},{"key":"10.1016\/j.tripleo.2006.11.033_bib12","doi-asserted-by":"crossref","first-page":"1471","DOI":"10.1902\/jop.2004.75.11.1471","article-title":"Patient evaluation of a novel non-injectable anesthetic gel: a multicenter crossover study comparing the gel to infiltration anesthesia during scaling and root planing","volume":"75","author":"Steenberghe","year":"2004","journal-title":"J Periodontal"},{"key":"10.1016\/j.tripleo.2006.11.033_bib13","first-page":"1747","article-title":"Quantification and analysis of pain in nonsurgical scaling and\/or root planing","volume":"135","author":"Magnusson","year":"2004","journal-title":"JADA"},{"key":"10.1016\/j.tripleo.2006.11.033_bib14","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1034\/j.1600-051X.2003.00017.x","article-title":"A placebo-controlled multi-centred evaluation of an anaesthetic gel (Oraqix) for periodontal therapy","volume":"30","author":"Donaldson","year":"2003","journal-title":"J Clin Periodontal"},{"key":"10.1016\/j.tripleo.2006.11.033_bib15","doi-asserted-by":"crossref","first-page":"230","DOI":"10.1080\/00016350310004106","article-title":"Plasma levels of lidocaine, o-toluidine, and prolicaine after application of 8.5 g Oraqix in patients with generalized periodontitis: effect on blood methemoglobin and tolerability","volume":"61","author":"Herdevall","year":"2003","journal-title":"Acta Odontol Scand"},{"key":"10.1016\/j.tripleo.2006.11.033_bib16","first-page":"311","article-title":"Psychophysical measurement on pain perception after administration of a topical anesthetic","volume":"22","author":"Kincheloe","year":"1991","journal-title":"Quintessence Int"},{"key":"10.1016\/j.tripleo.2006.11.033_bib17","first-page":"40","article-title":"Topical anesthesia: differentiating the pharmacological and phsychological contributions to efficacy","volume":"41","author":"Martin","year":"1994","journal-title":"Anesth Prog"},{"key":"10.1016\/j.tripleo.2006.11.033_bib18","first-page":"185","article-title":"Experimental studies of new topical anaesthetics on the oral mucosa","volume":"9","author":"Holst","year":"1985","journal-title":"Swed Dent J"},{"key":"10.1016\/j.tripleo.2006.11.033_bib19","first-page":"32","article-title":"Pharmacokinetics of EMLA cream applications to oral mucosa","volume":"44","author":"Vickers","year":"1997","journal-title":"Anesth Prog"},{"key":"10.1016\/j.tripleo.2006.11.033_bib20","doi-asserted-by":"crossref","first-page":"266","DOI":"10.1111\/j.1834-7819.1992.tb04742.x","article-title":"A clinical evaluation of three topical anesthetic agents","volume":"37","author":"Vickers","year":"1992","journal-title":"Australian Dent J"},{"key":"10.1016\/j.tripleo.2006.11.033_bib21","first-page":"11","article-title":"Comparison of topical EMLA 5% oral adhesive to Benzocaine 20% on the pain experienced during palatal anesthetic infiltration in children","volume":"23","author":"Primosch","year":"2001","journal-title":"Pediatr Dent"},{"key":"10.1016\/j.tripleo.2006.11.033_bib22","first-page":"32","article-title":"The use of EMLA for an Intraoral soft-tissue biopsy in a needle phobic: a case report","volume":"48","author":"Meechan","year":"2001","journal-title":"Anesth Prog"},{"key":"10.1016\/j.tripleo.2006.11.033_bib23","first-page":"497","article-title":"Evaluating the efficacy of EMLA topical anesthetic in sealant placement with rubber dam","volume":"26","author":"Lim","year":"2004","journal-title":"Pediatr Dent"},{"key":"10.1016\/j.tripleo.2006.11.033_bib24","first-page":"7","article-title":"A comparison of the effects of EMLA cream and topical 5% lidocaine on discomfort during gingival probing","volume":"42","author":"Donaldson","year":"1995","journal-title":"Anesth Prog"},{"key":"10.1016\/j.tripleo.2006.11.033_bib25","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/0266-4356(90)90131-4","article-title":"Topical anesthesia of gingival mucosa by 5% eutectic mixture of lignocaine and prilocaine or by lignocaine spray","volume":"28","author":"Hassio","year":"1990","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2006.11.033_bib26","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/0266-4356(92)90146-A","article-title":"Topical application of 5% eutectic mixture of lignocaine and prilocaine (EMLA) before removal of arch bars","volume":"30","author":"Pere","year":"1992","journal-title":"Br J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2006.11.033_bib27","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1097\/01.bsd.0000204503.07096.bf","article-title":"Methomoglobinemia after intubation in a patient with an unstable cervical fracture: a case report","volume":"19","author":"Basra","year":"2006","journal-title":"J Spinal Disord Tech"}],"container-title":["Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079210406009371?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079210406009371?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,24]],"date-time":"2019-04-24T20:21:06Z","timestamp":1556137266000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079210406009371"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,5]]},"references-count":27,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2007,5]]}},"alternative-id":["S1079210406009371"],"URL":"https:\/\/doi.org\/10.1016\/j.tripleo.2006.11.033","relation":{},"ISSN":["1079-2104"],"issn-type":[{"value":"1079-2104","type":"print"}],"subject":[],"published":{"date-parts":[[2007,5]]}}}