{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,5,31]],"date-time":"2025-05-31T04:57:08Z","timestamp":1748667428148},"reference-count":28,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2008,8,1]],"date-time":"2008-08-01T00:00:00Z","timestamp":1217548800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology"],"published-print":{"date-parts":[[2008,8]]},"DOI":"10.1016\/j.tripleo.2008.03.030","type":"journal-article","created":{"date-parts":[[2008,6,14]],"date-time":"2008-06-14T05:18:54Z","timestamp":1213420734000},"page":"e71-e76","source":"Crossref","is-referenced-by-count":19,"title":["Reaction of rat connective tissue to a new calcium hydroxide\u2013based sealer"],"prefix":"10.1016","volume":"106","author":[{"given":"Jo\u00e3o Eduardo","family":"Gomes-Filho","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro Fel\u00edcio Estrada","family":"Bernab\u00e9","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mauro Juvenal","family":"Nery","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Arlindo","family":"Otoboni-Filho","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Eloi","family":"Dezan-J\u00fanior","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariana Machado Teixeira","family":"de Moraes Costa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Max Douglas","family":"de Faria","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Simone","family":"Watanabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandra Cristina","family":"Gomes","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tripleo.2008.03.030_bib1","doi-asserted-by":"crossref","first-page":"166","DOI":"10.1016\/S0099-2399(76)80059-3","article-title":"Physical properties of root canal cements","volume":"2","author":"Grossman","year":"1976","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib2","first-page":"85","article-title":"Mechanism of action of calcium and hydroxyl ions of calcium hydroxide on tissue and bacteria","volume":"6","author":"Estrela","year":"1995","journal-title":"Braz Dent J"},{"key":"10.1016\/j.tripleo.2008.03.030_bib3","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/S0099-2399(81)80262-2","article-title":"pH changes in dental tissues after root canal filling with calcium hydroxide","volume":"7","author":"Tronstad","year":"1981","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib4","first-page":"67","article-title":"Calcium hydroxide and a corticosteroid-antibiotic association as dressings in cases of biopulpectomy","volume":"9","author":"Holland","year":"1998","journal-title":"Braz Detl J"},{"key":"10.1016\/j.tripleo.2008.03.030_bib5","doi-asserted-by":"crossref","first-page":"121","DOI":"10.1097\/00004770-200302000-00009","article-title":"A comparison of one versus two appointment endodontic therapy in dogs' teeth with apical periodontitis","volume":"29","author":"Holland","year":"2003","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib6","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1111\/j.1600-9657.1989.tb00350.x","article-title":"Periapical reactions to calcium hydroxide\u2013containing sealers and AH 26 in monkeys","volume":"5","author":"Tagger","year":"1989","journal-title":"Endod Dent Traumatol"},{"key":"10.1016\/j.tripleo.2008.03.030_bib7","doi-asserted-by":"crossref","first-page":"e86","DOI":"10.1016\/j.tripleo.2006.10.018","article-title":"Evaluation of pH and calcium ion release of Acroseal sealer in comparison with Apexit and Sealapex sealers","volume":"103","author":"Eldeniz","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib8","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1365-2591.2007.01211.x","article-title":"Cytotoxicity of new resin-, calcium hydroxide\u2013 and silicone-based root canal sealers on fibroblasts derived from human gingiva and L929 cell lines","volume":"40","author":"Eldeniz","year":"2007","journal-title":"Int Endod J"},{"key":"10.1016\/j.tripleo.2008.03.030_bib9","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1016\/S0099-2399(99)80134-4","article-title":"Reaction of rat connective tissue to implanted dentin tubes filled with mineral trioxide aggregate or calcium hydroxide","volume":"25","author":"Holland","year":"1999","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib10","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/S0099-2399(77)80017-4","article-title":"Reaction of human periapical tissue to pulp extirpation and immediate root canal filling with calcium hydroxide","volume":"3","author":"Holland","year":"1977","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib11","doi-asserted-by":"crossref","first-page":"355","DOI":"10.1016\/S0099-2399(81)80057-X","article-title":"Subcutaneous implantation for the biological evaluation of endodontic materials","volume":"7","author":"Olsson","year":"1981","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib12","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1046\/j.1365-2591.2003.00649.x","article-title":"Reactions of connective tissue to compomers, composite and amalgam root-end filling materials","volume":"36","author":"Ozbas","year":"2003","journal-title":"Int Endod J"},{"key":"10.1016\/j.tripleo.2008.03.030_bib13","doi-asserted-by":"crossref","first-page":"95","DOI":"10.1097\/00004770-200402000-00008","article-title":"Reactions of connective tissue to mineral trioxide aggregate and amalgam","volume":"30","author":"Yaltirik","year":"2004","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib14","first-page":"140","article-title":"Recommended standard practices for biological evaluation of dental materials","volume":"30","year":"1980","journal-title":"Int Dent J"},{"key":"10.1016\/j.tripleo.2008.03.030_bib15","series-title":"Revised American National Institute American Dental Asociation document no. 41 for recommended standard practices for biological evaluation of dental materials","year":"1979"},{"key":"10.1016\/j.tripleo.2008.03.030_bib16","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1016\/0030-4220(63)90078-1","article-title":"Histopathologic study of rat connective tissue responses to endodontic materials","volume":"16","author":"Guttuso","year":"1963","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib17","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1016\/S0099-2399(88)80236-X","article-title":"Histopathology and X-ray microanalysis of the subcutaneous tissue response to endodontic sealers","volume":"14","author":"Orstavik","year":"1988","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib18","doi-asserted-by":"crossref","first-page":"173","DOI":"10.1097\/00004770-200203000-00007","article-title":"Calcium salts deposition in rat connective tissue after implantation of calcium hydroxide-containing sealers","volume":"28","author":"Holland","year":"2002","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib19","first-page":"3","article-title":"Reaction of rat connective tissue to implanted dentin tube filled with mineral trioxide aggregate, Portland cement or calcium hydroxide","volume":"12","author":"Holland","year":"2001","journal-title":"Braz Dent J"},{"key":"10.1016\/j.tripleo.2008.03.030_bib20","doi-asserted-by":"crossref","first-page":"588","DOI":"10.1016\/S0099-2399(88)80055-4","article-title":"Release of calcium and hydroxyl ions from set endodontic sealers containing calcium hydroxide","volume":"14","author":"Tagger","year":"1988","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib21","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1016\/0003-9969(91)90074-5","article-title":"Odontoblast-like cytodifferentiation of human dental pulp cells in vitro in the presence of a calcium hydroxide-containing cement","volume":"36","author":"Seux","year":"1991","journal-title":"Arch Oral Biol"},{"key":"10.1016\/j.tripleo.2008.03.030_bib22","doi-asserted-by":"crossref","first-page":"541","DOI":"10.1177\/002203458506400407","article-title":"Effects of calcium hydroxide\u2013containing pulp-capping agents on pulp cell migration, proliferation, and differentiation","volume":"64","author":"Schroder","year":"1985","journal-title":"J Dent Res"},{"key":"10.1016\/j.tripleo.2008.03.030_bib23","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1016\/j.joen.2005.09.013","article-title":"Cytotoxicity of a new root canal filling material on human gingival fibroblasts","volume":"32","author":"Key","year":"2006","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib24","doi-asserted-by":"crossref","first-page":"767","DOI":"10.1023\/B:JMSM.0000032816.45489.54","article-title":"Root canal sealers induce cytotoxicity and necrosis","volume":"15","author":"Huang","year":"2004","journal-title":"J Mater Sci Mater Med"},{"key":"10.1016\/j.tripleo.2008.03.030_bib25","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1111\/j.1600-9657.1995.tb00493.x","article-title":"Evaluation of sealing ability, pH and flow rate of three calcium hydroxide\u2013based sealers","volume":"11","author":"Siqueira","year":"1995","journal-title":"Endod Dent Traumatol"},{"key":"10.1016\/j.tripleo.2008.03.030_bib26","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1097\/00004770-200007000-00002","article-title":"Evaluation of pH and calcium ion release of three root canal sealers","volume":"26","author":"Duarte","year":"2000","journal-title":"J Endod"},{"key":"10.1016\/j.tripleo.2008.03.030_bib27","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/j.1365-2591.1997.tb00730.x","article-title":"Antibacterial activity of calcium hydroxide-containing endodontic sealers on Enterococcus faecalis in vitro","volume":"30","author":"Fuss","year":"1997","journal-title":"Int Endod J"},{"key":"10.1016\/j.tripleo.2008.03.030_bib28","doi-asserted-by":"crossref","first-page":"535","DOI":"10.1016\/S0099-2399(85)80199-0","article-title":"Ability of a new calcium hydroxide root canal filling material to induce hard tissue formation","volume":"11","author":"Holland","year":"1985","journal-title":"J Endod"}],"container-title":["Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079210408002710?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079210408002710?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,27]],"date-time":"2018-12-27T16:27:11Z","timestamp":1545928031000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079210408002710"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,8]]},"references-count":28,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2008,8]]}},"alternative-id":["S1079210408002710"],"URL":"https:\/\/doi.org\/10.1016\/j.tripleo.2008.03.030","relation":{},"ISSN":["1079-2104"],"issn-type":[{"value":"1079-2104","type":"print"}],"subject":[],"published":{"date-parts":[[2008,8]]}}}