{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T11:18:00Z","timestamp":1761823080253},"reference-count":37,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2008,10,1]],"date-time":"2008-10-01T00:00:00Z","timestamp":1222819200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology"],"published-print":{"date-parts":[[2008,10]]},"DOI":"10.1016\/j.tripleo.2008.05.042","type":"journal-article","created":{"date-parts":[[2008,10,18]],"date-time":"2008-10-18T09:00:59Z","timestamp":1224320459000},"page":"548-555","source":"Crossref","is-referenced-by-count":24,"title":["Expression of bone resorption regulators (RANK, RANKL, and OPG) in odontogenic tumors"],"prefix":"10.1016","volume":"106","author":[{"given":"Fl\u00e1via R.","family":"Andrade","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D\u00e9bora P.","family":"Sousa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elismauro F.","family":"Mendon\u00e7a","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tarc\u00edlia A.","family":"Silva","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa S.","family":"Lara","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aline C.","family":"Batista","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tripleo.2008.05.042_bib1","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1016\/j.joms.2006.05.019","article-title":"Relative frequency of central odontogenic tumors: a study of 1,088 cases from northern California and comparison to studies from other parts of the world","volume":"64","author":"Buchner","year":"2006","journal-title":"J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2008.05.042_bib2","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1016\/j.ijom.2006.10.011","article-title":"Odontogenic tumours: a retrospective study of 1642 cases in a Chinese population","volume":"36","author":"Jing","year":"2007","journal-title":"Int J Oral Maxillofac Surg"},{"key":"10.1016\/j.tripleo.2008.05.042_bib3","series-title":"Pathology and genetics of head and neck tumors","first-page":"313","article-title":"Calcifying cystic odontogenic tumour","author":"Pr\u00e6torius","year":"2005"},{"key":"10.1016\/j.tripleo.2008.05.042_bib4","series-title":"Pathology and genetics of head and neck tumors","first-page":"305","article-title":"Adenomatoid odontogenic tumour","author":"Philipsen","year":"2005"},{"key":"10.1016\/j.tripleo.2008.05.042_bib5","series-title":"Pathology and genetics of head and neck tumors","first-page":"308","article-title":"Ameloblastic fibroma\/fibrodentinoma","author":"Slootweg","year":"2005"},{"key":"10.1016\/j.tripleo.2008.05.042_bib6","series-title":"Pathology and genetics of head and neck tumors","first-page":"302","article-title":"Calcifying epithelial odontogenic tumour","author":"Takata","year":"2005"},{"key":"10.1016\/j.tripleo.2008.05.042_bib7","series-title":"Pathology and genetics of head and neck tumors","first-page":"316","article-title":"Odontogenic myxoma\/myxofibroma","author":"Buchner","year":"2005"},{"key":"10.1016\/j.tripleo.2008.05.042_bib8","doi-asserted-by":"crossref","first-page":"331","DOI":"10.1038\/modpathol.3880527","article-title":"Odontogenic cysts, odontogenic tumors, fibroosseous, and giant cell lesions of the jaws","volume":"15","author":"Regezi","year":"2002","journal-title":"Mod Pathol"},{"key":"10.1016\/j.tripleo.2008.05.042_bib9","doi-asserted-by":"crossref","first-page":"372","DOI":"10.1097\/00000478-200303000-00011","article-title":"Clinicopathologic spectrum of the so-called calcifying odontogenic cysts","volume":"27","author":"Li","year":"2003","journal-title":"Am J Surg Pathol"},{"key":"10.1016\/j.tripleo.2008.05.042_bib10","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1016\/j.tripleo.2007.01.026","article-title":"Odontogenic myxoma: review of the literature and report of 30 cases from South Africa","volume":"104","author":"Noffke","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.tripleo.2008.05.042_bib11","doi-asserted-by":"crossref","first-page":"960","DOI":"10.1016\/j.oraloncology.2007.05.009","article-title":"Ameloblastic fibroma: a review of published studies with special reference to its nature and biologic behavior","volume":"43","author":"Chen","year":"2007","journal-title":"Oral Oncol"},{"key":"10.1016\/j.tripleo.2008.05.042_bib12","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.ooe.2005.08.002","article-title":"Management of an unusually large adenomatoid odontogenic tumor","volume":"41","author":"Shetty","year":"2005","journal-title":"Oral Oncol"},{"key":"10.1016\/j.tripleo.2008.05.042_bib13","doi-asserted-by":"crossref","first-page":"59","DOI":"10.1111\/j.1600-0714.2007.00567.x","article-title":"Extension of Pindborg tumor to the maxillary sinus: a case report","volume":"37","author":"Mohtasham","year":"2008","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.tripleo.2008.05.042_bib14","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1177\/154411130401500202","article-title":"New molecules in the tumor necrosis factor ligand and receptor superfamilies with importance for physiological and pathological bone resorption","volume":"15","author":"Lerner","year":"2004","journal-title":"Crit Rev Oral Biol Med"},{"key":"10.1016\/j.tripleo.2008.05.042_bib15","doi-asserted-by":"crossref","first-page":"1077","DOI":"10.1016\/j.biocel.2006.11.008","article-title":"RANK ligand","volume":"39","author":"Blair","year":"2007","journal-title":"Int J Biochem Cell Biol"},{"key":"10.1016\/j.tripleo.2008.05.042_bib16","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1006\/mcbr.2000.0205","article-title":"Dental cells express factors that regulate bone resorption","volume":"3","author":"Rani","year":"2000","journal-title":"Mol Cell Biol Res Commun"},{"key":"10.1016\/j.tripleo.2008.05.042_bib17","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1111\/j.1600-0765.2005.00814.x","article-title":"Inflammatory bone destruction and osteoimmunology","volume":"40","author":"Takayanagi","year":"2005","journal-title":"J. Periodont Res"},{"key":"10.1016\/j.tripleo.2008.05.042_bib18","doi-asserted-by":"crossref","first-page":"2307","DOI":"10.1002\/art.21211","article-title":"RANK and RANKL expression as markers of dendritic cell-T cell interactions in paired samples of rheumatoid synovium and lymph nodes","volume":"52","author":"Page","year":"2005","journal-title":"Arthritis Rheum"},{"key":"10.1016\/j.tripleo.2008.05.042_bib19","doi-asserted-by":"crossref","first-page":"480","DOI":"10.1016\/j.oraloncology.2004.11.006","article-title":"Immunohistochemical expression of RANK, GRalpha and CTR in central giant cell granuloma of the jaws","volume":"41","author":"Tob\u00f3n-Arroyave","year":"2005","journal-title":"Oral Oncol"},{"key":"10.1016\/j.tripleo.2008.05.042_bib20","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1038\/36593","article-title":"A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function","volume":"390","author":"Anderson","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.tripleo.2008.05.042_bib21","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1016\/j.tripleo.2007.06.009","article-title":"Comparative expression of RANK, RANKL, and OPG in keratocystic odontogenic tumors, ameloblastomas, and dentigerous cysts","volume":"105","author":"Silva","year":"2008","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.tripleo.2008.05.042_bib22","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1038\/nature01658","article-title":"Osteoclast differentiation and activation","volume":"423","author":"Boyle","year":"2003","journal-title":"Nature"},{"key":"10.1016\/j.tripleo.2008.05.042_bib23","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1016\/j.micpath.2007.03.001","article-title":"Regulation of RANKL and OPG gene expression in human gengival fibroblast and periodontal ligament cells by Porphyromonas gingivalis: a putative role of the Arg-gingipains","volume":"43","author":"Belibasakis","year":"2007","journal-title":"Microb Pathog"},{"key":"10.1016\/j.tripleo.2008.05.042_bib24","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1177\/154405910408300415","article-title":"Identification of RANKL in osteolytic lesions of the facial skeleton","volume":"83","author":"Tay","year":"2004","journal-title":"J Dent Res"},{"key":"10.1016\/j.tripleo.2008.05.042_bib25","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1111\/j.1600-0714.2004.00204.x","article-title":"Expression of parathyroid hormone\u2013related protein (PTHrP), osteoclast differentiation factor (ODF)\/receptor activator of nuclear factor-kappaB ligand (RANKL) and osteoclastogenesis inhibitory factor (OCIF)\/osteoprotegerin (OPG) in ameloblastomas","volume":"33","author":"Kumamoto","year":"2004","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.tripleo.2008.05.042_bib26","doi-asserted-by":"crossref","first-page":"637","DOI":"10.1016\/j.oraloncology.2005.02.008","article-title":"Ameloblastoma induces osteoclastogenesis: a possible role of ameloblastoma in expanding in the bone","volume":"41","author":"Sandra","year":"2005","journal-title":"Oral Oncol"},{"key":"10.1016\/j.tripleo.2008.05.042_bib27","first-page":"49","article-title":"RANK\/RANKL\/OPG: new therapeutic targets in bone tumours and associated osteolysis","volume":"1704","author":"Wittrant","year":"2004","journal-title":"Biochim Biophys Acta"},{"key":"10.1016\/j.tripleo.2008.05.042_bib28","doi-asserted-by":"crossref","first-page":"1937","DOI":"10.1177\/00220345000790120301","article-title":"Osteoprotegerin and osteoclasts differentiation factor in tooth eruption","volume":"79","author":"Wise","year":"2000","journal-title":"J Dent Res"},{"key":"10.1016\/j.tripleo.2008.05.042_bib29","doi-asserted-by":"crossref","first-page":"404","DOI":"10.1016\/j.tripleo.2005.10.054","article-title":"Receptor activator NFkappaB-ligand and osteoprotegerin protein expression in human periapical cysts and granulomas","volume":"102","author":"Menezes","year":"2006","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.tripleo.2008.05.042_bib30","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1111\/j.1601-0825.2005.01191.x","article-title":"RANKL in human periapical granuloma: possible involvement in periapical bone destruction","volume":"12","author":"Vernal","year":"2006","journal-title":"Oral Dis"},{"key":"10.1016\/j.tripleo.2008.05.042_bib31","doi-asserted-by":"crossref","first-page":"415","DOI":"10.1016\/j.oraloncology.2005.09.009","article-title":"Osteoprotegerin (OPG) binds with tumor necrosis factor-related apoptosis-inducing ligand (TRAIL): suppression of TRAIL-induced apoptosis in ameloblastomas","volume":"42","author":"Sandra","year":"2006","journal-title":"Oral Oncol"},{"key":"10.1016\/j.tripleo.2008.05.042_bib32","doi-asserted-by":"crossref","first-page":"e24","DOI":"10.1016\/j.tripleo.2006.12.056","article-title":"Expression of OPG, RANKL, and TRAIL in odontogenic keratocysts (OKC): an immunohistochemical study","volume":"103","author":"Zakopoulos","year":"2007","journal-title":"Oral Surg Oral Med Oral Pathol Oral Radiol Endod"},{"key":"10.1016\/j.tripleo.2008.05.042_bib33","doi-asserted-by":"crossref","first-page":"483","DOI":"10.1111\/j.1600-0714.2005.00357.x","article-title":"Odontogenic tumors: a study of 340 cases in a Brazilian population","volume":"34","author":"Fernandes","year":"2005","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.tripleo.2008.05.042_bib34","doi-asserted-by":"crossref","first-page":"392","DOI":"10.1111\/j.1600-0714.2006.00451.x","article-title":"An analysis of oral and maxillofacial pathology found in adults over a 30-year period","volume":"35","author":"Jones","year":"2006","journal-title":"J Oral Pathol Med"},{"key":"10.1016\/j.tripleo.2008.05.042_bib35","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1016\/j.cytogfr.2003.10.005","article-title":"IL-6, RANKL, TNF-alpha\/IL-1: interrelations in bone resorption pathophysiology","volume":"15","author":"Steeve","year":"2004","journal-title":"Cytokine Growth Factor Rev"},{"key":"10.1016\/j.tripleo.2008.05.042_bib36","doi-asserted-by":"crossref","first-page":"5055","DOI":"10.1210\/en.142.12.5050","article-title":"Minireview: the OPG\/RANKL\/RANK system","volume":"142","author":"Khosla","year":"2001","journal-title":"Endocrinology"},{"key":"10.1016\/j.tripleo.2008.05.042_bib37","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.molmed.2005.11.007","article-title":"RANKL-RANK signaling in osteoclastogenesis and bone disease","volume":"12","author":"Wada","year":"2006","journal-title":"Trends Mol Med"}],"container-title":["Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079210408003867?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1079210408003867?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,12,25]],"date-time":"2018-12-25T01:20:29Z","timestamp":1545700829000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1079210408003867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,10]]},"references-count":37,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2008,10]]}},"alternative-id":["S1079210408003867"],"URL":"https:\/\/doi.org\/10.1016\/j.tripleo.2008.05.042","relation":{},"ISSN":["1079-2104"],"issn-type":[{"value":"1079-2104","type":"print"}],"subject":[],"published":{"date-parts":[[2008,10]]}}}