{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T22:30:01Z","timestamp":1779229801378,"version":"3.51.4"},"reference-count":116,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,1,1]],"date-time":"2026-01-01T00:00:00Z","timestamp":1767225600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100018570","name":"Special Project of Central Government for Local Science and Technology Development of Hubei Province","doi-asserted-by":"publisher","award":["24ZYQA05"],"award-info":[{"award-number":["24ZYQA05"]}],"id":[{"id":"10.13039\/501100018570","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100022817","name":"Lanzhou University Second Hospital","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100022817","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Transplantation Reviews"],"published-print":{"date-parts":[[2026,1]]},"DOI":"10.1016\/j.trre.2025.100979","type":"journal-article","created":{"date-parts":[[2025,11,29]],"date-time":"2025-11-29T08:05:59Z","timestamp":1764403559000},"page":"100979","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"title":["Cryptococcosis in kidney transplant recipients: Pathogenesis, clinical challenges, and evolving therapeutic strategies"],"prefix":"10.1016","volume":"40","author":[{"given":"Yalong","family":"Zhang","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rui","family":"Yan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hao","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kangyu","family":"Wang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiangwei","family":"Man","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li","family":"Yang","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.trre.2025.100979_bb0005","doi-asserted-by":"crossref","first-page":"1725","DOI":"10.1056\/NEJM199912023412303","article-title":"Comparison of mortality in all patients on dialysis, patients on dialysis awaiting transplantation, and recipients of a first cadaveric transplant","volume":"341","author":"Wolfe","year":"1999","journal-title":"N Engl J Med"},{"key":"10.1016\/j.trre.2025.100979_bb0010","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s11046-015-9875-4","article-title":"Invasive fungal infections in renal transplant recipients: epidemiology and risk factors","volume":"180","author":"Sahin","year":"2015","journal-title":"Mycopathologia"},{"key":"10.1016\/j.trre.2025.100979_bb0015","doi-asserted-by":"crossref","first-page":"1101","DOI":"10.1086\/651262","article-title":"Invasive fungal infections among organ transplant recipients: results of the transplant-associated infection surveillance network (TRANSNET)","volume":"50","author":"Pappas","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0020","doi-asserted-by":"crossref","first-page":"639","DOI":"10.2217\/fmb.12.28","article-title":"Invasive fungal infections in solid organ transplant recipients","volume":"7","author":"Shoham","year":"2012","journal-title":"Future Microbiol"},{"key":"10.1016\/j.trre.2025.100979_bb0025","doi-asserted-by":"crossref","first-page":"120","DOI":"10.5527\/wjn.v12.i5.120","article-title":"Cryptococcosis in kidney transplant recipients: current understanding and practices","volume":"12","author":"Meena","year":"2023","journal-title":"World J Nephrol"},{"key":"10.1016\/j.trre.2025.100979_bb0030","doi-asserted-by":"crossref","first-page":"587","DOI":"10.4103\/IJPM.IJPM_306_19","article-title":"Fungal infection in post-renal transplant patient: single-center experience","volume":"63","author":"Gupta","year":"2020","journal-title":"Indian J Pathol Microbiol"},{"key":"10.1016\/j.trre.2025.100979_bb0035","doi-asserted-by":"crossref","first-page":"971","DOI":"10.1016\/j.transproceed.2015.03.040","article-title":"Invasive fungal infections after kidney transplantation: a single-center experience","volume":"47","author":"Santos","year":"2015","journal-title":"Transplant Proc"},{"key":"10.1016\/j.trre.2025.100979_bb0040","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.idc.2015.10.006","article-title":"Cryptococcosis","volume":"30","author":"Maziarz","year":"2016","journal-title":"Infect Dis Clin North Am"},{"key":"10.1016\/j.trre.2025.100979_bb0045","doi-asserted-by":"crossref","DOI":"10.1093\/mmy\/myad011","article-title":"Characteristics, mortality, associated variables with death, and therapeutic response among HIV-positive, solid organ transplant (SOT), and non-HIV-positive\/non-transplant (NHNT) patients with cryptococcosis: first multicenter cohort study in Brazil","volume":"61","author":"Bridi Cavassin","year":"2023","journal-title":"Med Mycol"},{"key":"10.1016\/j.trre.2025.100979_bb0050","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1399-3062.2010.00492.x","article-title":"Epidemiology and outcome of invasive fungal infections in solid organ transplant recipients","volume":"12","author":"Neofytos","year":"2010","journal-title":"Transpl Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0055","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofaf263","article-title":"High mortality and associated risk factors in kidney transplant recipients with cryptococcosis-a nationwide cohort study over a decade using USRDS data","volume":"12","author":"Fiorica","year":"2025","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0060","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.13543","article-title":"Cryptococcosis in solid organ transplantation-guidelines from the American society of transplantation infectious diseases community of practice","volume":"33","author":"Baddley","year":"2019","journal-title":"Clin Transplant"},{"key":"10.1016\/j.trre.2025.100979_bb0065","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofx004","article-title":"Epidemiology of cryptococcosis and cryptococcal meningitis in a large retrospective cohort of patients after solid organ transplantation","volume":"4","author":"George","year":"2017","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0070","doi-asserted-by":"crossref","first-page":"S514","DOI":"10.1016\/j.ekir.2022.07.124","article-title":"Pos-106 profile of cryptococcal infections in renal transplant recipients in a tertiary care hospital in North India","volume":"7","author":"Shenoy","year":"2022","journal-title":"Kidney Int Rep"},{"key":"10.1016\/j.trre.2025.100979_bb0075","article-title":"Comparison of different therapeutic approaches for pulmonary cryptococcosis in kidney transplant recipients: a 15-year retrospective analysis","volume":"10","author":"Chen","year":"2023","journal-title":"Front Med (Lausanne)"},{"key":"10.1016\/j.trre.2025.100979_bb0080","doi-asserted-by":"crossref","DOI":"10.1155\/2019\/7165160","article-title":"Cryptococcosis in patients following kidney transplantation: a 9-year retrospective clinical analysis at a Chinese tertiary hospital","volume":"2019","author":"Yang","year":"2019","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.trre.2025.100979_bb0085","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.ijid.2014.05.028","article-title":"Cryptococcosis in kidney transplant recipients in a Chinese university hospital and a review of published cases","volume":"26","author":"Yang","year":"2014","journal-title":"Int J Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0090","doi-asserted-by":"crossref","first-page":"1911","DOI":"10.1111\/ajt.16433","article-title":"Cryptococcus transmission through solid organ transplantation in the United States: a report from the ad hoc disease transmission advisory committee","volume":"21","author":"Penumarthi","year":"2021","journal-title":"Am J Transplant"},{"key":"10.1016\/j.trre.2025.100979_bb0095","doi-asserted-by":"crossref","first-page":"1550","DOI":"10.1128\/CVI.00242-07","article-title":"Serologic evidence for reactivation of cryptococcosis in solid-organ transplant recipients","volume":"14","author":"Saha","year":"2007","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.trre.2025.100979_bb0100","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2023.1131641","article-title":"Interactions between antifungals and everolimus against Cryptococcus neoformans","volume":"13","author":"Liang","year":"2023","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.trre.2025.100979_bb0105","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.amjms.2019.10.008","article-title":"Risk factors associated with invasive fungal infections in kidney transplant patients","volume":"359","author":"Leitheiser","year":"2020","journal-title":"Am J Med Sci"},{"key":"10.1016\/j.trre.2025.100979_bb0110","doi-asserted-by":"crossref","DOI":"10.1111\/tid.12836","article-title":"A cluster of donor-derived Cryptococcus neoformans infection affecting lung, liver, and kidney transplant recipients: case report and review of literature","volume":"20","author":"Camargo","year":"2018","journal-title":"Transpl Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0115","doi-asserted-by":"crossref","DOI":"10.3389\/fped.2023.1265023","article-title":"Approach to suspected donor-derived infections","volume":"11","author":"Bahakel","year":"2023","journal-title":"Front Pediatr"},{"key":"10.1016\/j.trre.2025.100979_bb0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.mycmed.2023.101388","article-title":"Cryptococcal meningitis in a non-HIV patient with solid organ transplantation","volume":"33","author":"Ugur","year":"2023","journal-title":"J Mycol Med"},{"key":"10.1016\/j.trre.2025.100979_bb0125","doi-asserted-by":"crossref","DOI":"10.4414\/smw.2016.14281","article-title":"Common invasive fungal diseases: an overview of invasive candidiasis, aspergillosis, cryptococcosis, and Pneumocystis pneumonia","volume":"146","author":"Schmiedel","year":"2016","journal-title":"Swiss Med Wkly"},{"key":"10.1016\/j.trre.2025.100979_bb0130","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1111\/j.1399-3062.2006.00149.x","article-title":"Cryptococcosis in liver and kidney transplant recipients receiving anti-thymocyte globulin or alemtuzumab","volume":"9","author":"Silveira","year":"2007","journal-title":"Transpl Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.trim.2022.101741","article-title":"Systematic review and meta-analysis of calcineurin inhibitors on long-term prognosis of renal transplant patients","volume":"75","author":"Yang","year":"2022","journal-title":"Transpl Immunol"},{"key":"10.1016\/j.trre.2025.100979_bb0140","doi-asserted-by":"crossref","first-page":"756","DOI":"10.1086\/511438","article-title":"Cryptococcus neoformans in organ transplant recipients: impact of calcineurin-inhibitor agents on mortality","volume":"195","author":"Singh","year":"2007","journal-title":"J Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0145","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.1011115","article-title":"Host populations, challenges, and commercialization of cryptococcal vaccines","volume":"19","author":"Del Poeta","year":"2023","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.trre.2025.100979_bb0150","doi-asserted-by":"crossref","first-page":"62","DOI":"10.1038\/s41572-023-00472-z","article-title":"Cryptococcal meningitis","volume":"9","author":"Tugume","year":"2023","journal-title":"Nat Rev Dis Primers"},{"key":"10.1016\/j.trre.2025.100979_bb0155","doi-asserted-by":"crossref","first-page":"2206","DOI":"10.1002\/eji.202149349","article-title":"Cryptococcus gattii polysaccharide capsule: an insight on fungal-host interactions and vaccine studies","volume":"51","author":"Freitas","year":"2021","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.trre.2025.100979_bb0160","doi-asserted-by":"crossref","first-page":"129","DOI":"10.3389\/fmed.2019.00129","article-title":"Immunomodulatory role of capsular polysaccharides constituents of Cryptococcus neoformans","volume":"6","author":"Decote-Ricardo","year":"2019","journal-title":"Front Med (Lausanne)"},{"key":"10.1016\/j.trre.2025.100979_bb0165","doi-asserted-by":"crossref","first-page":"133","DOI":"10.1093\/mmy\/myy086","article-title":"Pulmonary cryptococcosis: a review of pathobiology and clinical aspects","volume":"57","author":"Setianingrum","year":"2019","journal-title":"Med Mycol"},{"key":"10.1016\/j.trre.2025.100979_bb0170","doi-asserted-by":"crossref","DOI":"10.1371\/journal.ppat.0020120","article-title":"Direct inhibition of T-cell responses by the Cryptococcus capsular polysaccharide glucuronoxylomannan","volume":"2","author":"Yauch","year":"2006","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.trre.2025.100979_bb0175","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1016\/j.mib.2013.03.006","article-title":"Titan cells in Cryptococcus neoformans: cells with a giant impact","volume":"16","author":"Zaragoza","year":"2013","journal-title":"Curr Opin Microbiol"},{"key":"10.1016\/j.trre.2025.100979_bb0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2020.110550","article-title":"Immune defence to invasive fungal infections: a comprehensive review","volume":"130","author":"Pathakumari","year":"2020","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.trre.2025.100979_bb0185","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00158-11","article-title":"Dynamics of Cryptococcus neoformans-macrophage interactions reveal that fungal background influences outcome during cryptococcal meningoencephalitis in humans","volume":"2","author":"Alanio","year":"2011","journal-title":"mBio"},{"key":"10.1016\/j.trre.2025.100979_bb0190","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00799-19","article-title":"Pulmonary iron limitation induced by exogenous type I IFN protects mice from Cryptococcus gattii independently of T cells","volume":"10","author":"Davis","year":"2019","journal-title":"mBio"},{"key":"10.1016\/j.trre.2025.100979_bb0195","doi-asserted-by":"crossref","DOI":"10.1177\/20406223211063055","article-title":"Efficacy of tacrolimus as long-term immunotherapy for neuronal surface antibody-mediated autoimmune encephalitis","volume":"13","author":"Liu","year":"2022","journal-title":"Ther Adv Chronic Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0200","doi-asserted-by":"crossref","first-page":"1204","DOI":"10.1073\/pnas.85.4.1204","article-title":"Glucocorticoids selectively inhibit the transcription of the interleukin 1 beta gene and decrease the stability of interleukin 1 beta mRNA","volume":"85","author":"Lee","year":"1988","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.trre.2025.100979_bb0205","article-title":"Natural alkaloid tryptanthrin exhibits novel anticryptococcal activity","author":"Lin","year":"2020","journal-title":"Med Mycol"},{"key":"10.1016\/j.trre.2025.100979_bb0210","doi-asserted-by":"crossref","first-page":"375","DOI":"10.3201\/eid0703.017302","article-title":"Cryptococcus neoformans infection in organ transplant recipients: variables influencing clinical characteristics and outcome","volume":"7","author":"Husain","year":"2001","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0215","doi-asserted-by":"crossref","first-page":"1062","DOI":"10.1086\/656584","article-title":"Unrecognized pretransplant and donor-derived cryptococcal disease in organ transplant recipients","volume":"51","author":"Sun","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0220","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.3201\/eid2810.220522","article-title":"Cluster of donor-derived cryptococcosis after liver and kidney transplantation","volume":"28","author":"Sha","year":"2022","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0225","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms13010207","article-title":"Fungal infections in kidney transplant recipients: a comprehensive narrative review","volume":"13","author":"Mazzitelli","year":"2025","journal-title":"Microorganisms"},{"key":"10.1016\/j.trre.2025.100979_bb0230","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1038\/nrneurol.2016.167","article-title":"Cryptococcal meningitis: epidemiology, immunology, diagnosis and therapy","volume":"13","author":"Williamson","year":"2017","journal-title":"Nat Rev Neurol"},{"key":"10.1016\/j.trre.2025.100979_bb0235","doi-asserted-by":"crossref","first-page":"e01101","DOI":"10.1128\/mBio.01101-14","article-title":"Invasion of the central nervous system by Cryptococcus neoformans requires a secreted fungal metalloprotease","volume":"5","author":"Vu","year":"2014","journal-title":"mBio"},{"key":"10.1016\/j.trre.2025.100979_bb0240","doi-asserted-by":"crossref","DOI":"10.3390\/pathogens11060699","article-title":"Cryptococcal meningitis in kidney transplant recipients: a two-decade cohort study in France","volume":"11","author":"Tardieu","year":"2022","journal-title":"Pathogens"},{"key":"10.1016\/j.trre.2025.100979_bb0245","doi-asserted-by":"crossref","first-page":"242","DOI":"10.1007\/s13730-024-00939-2","article-title":"Unusual late presentation of cryptococcal meningitis with simultaneous CMV antigenemia in a kidney transplant recipient","volume":"14","author":"Mok","year":"2025","journal-title":"CEN Case Rep"},{"key":"10.1016\/j.trre.2025.100979_bb0250","doi-asserted-by":"crossref","first-page":"794","DOI":"10.1056\/NEJM198909213211205","article-title":"Infections with Cryptococcus neoformans in the acquired immunodeficiency syndrome","volume":"321","author":"Chuck","year":"1989","journal-title":"N Engl J Med"},{"key":"10.1016\/j.trre.2025.100979_bb0255","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofac416","article-title":"Therapeutic lumbar punctures in human immunodeficiency virus-associated cryptococcal meningitis: should opening pressure direct management?","volume":"9","author":"Kagimu","year":"2022","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0260","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/S1473-3099(17)30243-8","article-title":"Global burden of disease of HIV-associated cryptococcal meningitis: an updated analysis","volume":"17","author":"Rajasingham","year":"2017","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0265","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1097\/TP.0b013e3181814e76","article-title":"Central nervous system cryptococcosis in solid organ transplant recipients: clinical relevance of abnormal neuroimaging findings","volume":"86","author":"Singh","year":"2008","journal-title":"Transplantation"},{"key":"10.1016\/j.trre.2025.100979_bb0270","doi-asserted-by":"crossref","first-page":"e246","DOI":"10.1016\/S1473-3099(20)30784-2","volume":"21","author":"Hoenigl","year":"2021","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0275","doi-asserted-by":"crossref","DOI":"10.1136\/bcr-2019-230255","article-title":"Hemophagocytic lymphohistiocytosis: a rare association with pulmonary cryptococcosis","volume":"12","author":"Singh","year":"2019","journal-title":"BMJ Case Rep"},{"key":"10.1016\/j.trre.2025.100979_bb0280","doi-asserted-by":"crossref","first-page":"371","DOI":"10.14740\/jocmr2104w","article-title":"Fungal infections in renal transplant patients","volume":"7","author":"Khan","year":"2015","journal-title":"J Clin Med Res"},{"key":"10.1016\/j.trre.2025.100979_bb0285","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1016\/j.mmcr.2020.03.004","article-title":"Skin cryptococcosis in an immunocompromised renal-transplant recipient","volume":"28","author":"Jarasuniene","year":"2020","journal-title":"Med Mycol Case Rep"},{"key":"10.1016\/j.trre.2025.100979_bb0290","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/s12879-023-08066-6","article-title":"Isolated cryptococcal osteomyelitis of the sacrum in an immunocompetent patient: a case report and literature review","volume":"23","author":"Zhong","year":"2023","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0295","doi-asserted-by":"crossref","first-page":"119","DOI":"10.18240\/ijo.2022.01.18","article-title":"Ophthalmic manifestations of Cryptococcus gattii species complex: a case series and review of the literature","volume":"15","author":"McCabe","year":"2022","journal-title":"Int J Ophthalmol"},{"key":"10.1016\/j.trre.2025.100979_bb0300","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1001\/archinte.1981.00340010120023","article-title":"Cryptococcal pyelonephritis and disseminated cryptococcosis in a renal transplant recipient","volume":"141","author":"Hellman","year":"1981","journal-title":"Arch Intern Med"},{"key":"10.1016\/j.trre.2025.100979_bb0305","first-page":"27","article-title":"Laryngeal cryptococcus: a rare cause of hoarseness in renal allograft recipient","volume":"6","author":"Sandhu","year":"2017","journal-title":"J Nephropharmacol"},{"key":"10.1016\/j.trre.2025.100979_bb0310","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/s40475-015-0046-y","article-title":"Cryptococcal meningitis: diagnosis and management update","volume":"2","author":"Abassi","year":"2015","journal-title":"Curr Trop Med Rep"},{"key":"10.1016\/j.trre.2025.100979_bb0315","doi-asserted-by":"crossref","first-page":"1268","DOI":"10.1093\/cid\/ciaa1243","article-title":"Cryptococcal antigen in serum and cerebrospinal fluid for detecting cryptococcal meningitis in adults living with human immunodeficiency virus: systematic review and meta-analysis of diagnostic test accuracy studies","volume":"72","author":"Temfack","year":"2021","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0320","doi-asserted-by":"crossref","DOI":"10.1093\/mmy\/myae116","article-title":"Evaluation of the diagnostic performance of a semi-quantitative lateral flow assay for the detection of Cryptococcus antigen in serum and cerebrospinal fluid specimens","volume":"63","author":"Casta\u00f1eda-Torres","year":"2024","journal-title":"Med Mycol"},{"key":"10.1016\/j.trre.2025.100979_bb0325","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1086\/649858","article-title":"Clinical practice guidelines for the management of cryptococcal disease: 2010 update by the infectious diseases society of america","volume":"50","author":"Perfect","year":"2010","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0330","doi-asserted-by":"crossref","first-page":"45","DOI":"10.3201\/eid2001.130906","article-title":"Multisite validation of cryptococcal antigen lateral flow assay and quantification by laser thermal contrast","volume":"20","author":"Boulware","year":"2014","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0335","article-title":"Neuroimaging of cryptococcal meningitis in patients without human immunodeficiency virus: data from a multi-center cohort study","volume":"9","author":"Anjum","year":"2023","journal-title":"J Fungi (Basel)"},{"key":"10.1016\/j.trre.2025.100979_bb0340","doi-asserted-by":"crossref","first-page":"980","DOI":"10.1128\/CMR.00126-13","article-title":"Cryptococcus gattii infections","volume":"27","author":"Chen","year":"2014","journal-title":"Clin Microbiol Rev"},{"key":"10.1016\/j.trre.2025.100979_bb0345","doi-asserted-by":"crossref","first-page":"570","DOI":"10.3109\/13693780903437876","article-title":"Cryptococcal meningitis in non-HIV-infected patients in a Chinese tertiary care hospital, 1997-2007","volume":"48","author":"Zhu","year":"2010","journal-title":"Med Mycol"},{"key":"10.1016\/j.trre.2025.100979_bb0350","doi-asserted-by":"crossref","DOI":"10.1016\/j.diagmicrobio.2025.116944","article-title":"Evaluating clinical outcome in non-HIV associated cryptococcal meningitis with negative CSF culture using microscopic quantitative cryptococcal counting","volume":"113","author":"Liu","year":"2025","journal-title":"Diagn Microbiol Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0355","article-title":"An unusual case of pulmonary Cryptococcus","volume":"10","author":"Aslam","year":"2018","journal-title":"Cureus"},{"key":"10.1016\/j.trre.2025.100979_bb0360","article-title":"Grocott methenamine silver staining is the optimal approach to histological diagnosis of pulmonary cryptococcosis","volume":"13","author":"Wang","year":"2022","journal-title":"Front Microbiol"},{"key":"10.1016\/j.trre.2025.100979_bb0365","doi-asserted-by":"crossref","DOI":"10.1093\/mmy\/myae126","article-title":"Cryptococcus neoformans\/gattii and histoplasma capsulatum var. capsulatum infections on tissue sections: diagnostic pitfalls and relevance of an integrated histomolecular diagnosis","volume":"63","author":"Trecourt","year":"2024","journal-title":"Med Mycol"},{"key":"10.1016\/j.trre.2025.100979_bb0370","article-title":"Subculturing and gram staining of blood cultures flagged negative by the BACTEC\u2122 FX system: optimizing the workflow for detection of Cryptococcus neoformans in clinical specimens","volume":"14","author":"Liu","year":"2023","journal-title":"Front Microbiol"},{"key":"10.1016\/j.trre.2025.100979_bb0375","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1590\/S0037-86822010000400029","article-title":"Cryptococcus gattii meningoencephalitis in an HIV-negative patient from the Peruvian Andes","volume":"43","author":"Gutierrez","year":"2010","journal-title":"Rev Soc Bras Med Trop"},{"key":"10.1016\/j.trre.2025.100979_bb0380","doi-asserted-by":"crossref","first-page":"474","DOI":"10.1128\/JCM.02635-15","article-title":"Does the capsule interfere with performance of matrix-assisted laser desorption ionization-time of flight mass spectrometry for identification of Cryptococcus neoformans and Cryptococcus gattii?","volume":"54","author":"Thomaz","year":"2016","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.trre.2025.100979_bb0385","doi-asserted-by":"crossref","first-page":"3107","DOI":"10.1128\/AAC.06252-11","article-title":"Cryptococcus neoformans-Cryptococcus gattii species complex: an international study of wild-type susceptibility endpoint distributions and epidemiological cutoff values for amphotericin B and flucytosine","volume":"56","author":"Espinel-Ingroff","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.trre.2025.100979_bb0390","doi-asserted-by":"crossref","first-page":"1","DOI":"10.3109\/10408410903241444","article-title":"Epidemiology of invasive mycoses in North America","volume":"36","author":"Pfaller","year":"2010","journal-title":"Crit Rev Microbiol"},{"key":"10.1016\/j.trre.2025.100979_bb0395","doi-asserted-by":"crossref","DOI":"10.1590\/s1678-9946202163057","article-title":"Cost-effectiveness analysis and budgetary impact of the cryptococcal antigen lateral flow assay (CRAG-LFA) implementation for the screening and diagnosis of cryptococcosis in asymptomatic people living with HIV in Brazil","volume":"63","author":"Vianna","year":"2021","journal-title":"Rev Inst Med Trop Sao Paulo"},{"key":"10.1016\/j.trre.2025.100979_bb0400","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1186\/1758-2652-15-15","article-title":"Prevalence and factors associated with cryptococcal antigenemia among severely immunosuppressed HIV-infected adults in Uganda: a cross-sectional study","volume":"15","author":"Oyella","year":"2012","journal-title":"J Int AIDS Soc"},{"key":"10.1016\/j.trre.2025.100979_bb0405","doi-asserted-by":"crossref","first-page":"321","DOI":"10.1093\/cid\/cir379","article-title":"Evaluation of a newly developed lateral flow immunoassay for the diagnosis of cryptococcosis","volume":"53","author":"Lindsley","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0410","doi-asserted-by":"crossref","first-page":"1019","DOI":"10.1093\/cid\/cir613","article-title":"Evaluation of a novel point-of-care cryptococcal antigen test on serum, plasma, and urine from patients with HIV-associated cryptococcal meningitis","volume":"53","author":"Jarvis","year":"2011","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0415","doi-asserted-by":"crossref","first-page":"333","DOI":"10.1378\/chest.129.2.333","article-title":"Pulmonary cryptococcosis: comparison of clinical and radiographic characteristics in immunocompetent and immunocompromised patients","volume":"129","author":"Chang","year":"2006","journal-title":"Chest"},{"key":"10.1016\/j.trre.2025.100979_bb0420","doi-asserted-by":"crossref","first-page":"1988","DOI":"10.1128\/CVI.00446-12","article-title":"Comparison of four assays for the detection of cryptococcal antigen","volume":"19","author":"Binnicker","year":"2012","journal-title":"Clin Vaccine Immunol"},{"key":"10.1016\/j.trre.2025.100979_bb0425","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0049541","article-title":"Clinical utility of the cryptococcal antigen lateral flow assay in a diagnostic mycology laboratory","volume":"7","author":"McMullan","year":"2012","journal-title":"PloS One"},{"key":"10.1016\/j.trre.2025.100979_bb0430","doi-asserted-by":"crossref","first-page":"179","DOI":"10.1016\/j.riam.2018.05.003","article-title":"Microbiological diagnosis of invasive mycosis","volume":"35","author":"Garc\u00eda","year":"2018","journal-title":"Rev Iberoam Micol"},{"key":"10.1016\/j.trre.2025.100979_bb0435","article-title":"Infections due to rare Cryptococcus species. A literature review","volume":"7","author":"Morales-L\u00f3pez","year":"2021","journal-title":"J Fungi (Basel)"},{"key":"10.1016\/j.trre.2025.100979_bb0440","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1080\/13693780902953886","article-title":"Consensus multi-locus sequence typing scheme for Cryptococcus neoformans and Cryptococcus gattii","volume":"47","author":"Meyer","year":"2009","journal-title":"Med Mycol"},{"key":"10.1016\/j.trre.2025.100979_bb0445","doi-asserted-by":"crossref","DOI":"10.1590\/1414-431x20209056","article-title":"Visible DNA microarray and loop-mediated isothermal amplification (LAMP) for the identification of Cryptococcus species recovered from culture medium and cerebrospinal fluid of patients with meningitis","volume":"53","author":"Stivanelli","year":"2020","journal-title":"Braz J Med Biol Res"},{"key":"10.1016\/j.trre.2025.100979_bb0450","article-title":"Editorial: mNGS for fungal pulmonary infection diagnostics","volume":"12","author":"Li","year":"2022","journal-title":"Front Cell Infect Microbiol"},{"key":"10.1016\/j.trre.2025.100979_bb0455","doi-asserted-by":"crossref","first-page":"3656","DOI":"10.1038\/s41598-025-86481-2","article-title":"Comparison of mNGS with conventional methods for diagnosis of cryptococcal meningitis: a retrospective study","volume":"15","author":"Jiang","year":"2025","journal-title":"Sci Rep"},{"key":"10.1016\/j.trre.2025.100979_bb0460","article-title":"Guideline for the clinical diagnosis and treatment of cryptococcosis in kidney transplant recipients","volume":"46","author":"Branch of Organ Transplantation, Chinese Medical Association","year":"2025","journal-title":"Chin J Organ Transplant"},{"key":"10.1016\/j.trre.2025.100979_bb0465","article-title":"Diagnosis and management of central nervous system cryptococcal infections in HIV-infected adults","volume":"5","author":"Skipper","year":"2019","journal-title":"J Fungi (Basel)"},{"key":"10.1016\/j.trre.2025.100979_bb0470","doi-asserted-by":"crossref","first-page":"1775","DOI":"10.1086\/599112","article-title":"A phase II randomized trial of amphotericin B alone or combined with fluconazole in the treatment of HIV-associated cryptococcal meningitis","volume":"48","author":"Pappas","year":"2009","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0475","doi-asserted-by":"crossref","first-page":"1109","DOI":"10.1056\/NEJMoa2111904","article-title":"Single-dose liposomal amphotericin B treatment for cryptococcal meningitis","volume":"386","author":"Jarvis","year":"2022","journal-title":"N Engl J Med"},{"key":"10.1016\/j.trre.2025.100979_bb0480","series-title":"Guidelines for the diagnosis, prevention and management of cryptococcal disease in HIV-infected adults, adolescents and children: supplement to the 2016 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection","volume":"2018","author":"WHO Guidelines Approved by the Guidelines Review Committee","year":"2018"},{"key":"10.1016\/j.trre.2025.100979_bb0485","first-page":"356","article-title":"Drug-drug interaction between tacrolimus and fluconazole in a kidney transplant recipient","volume":"22","author":"Ferchichi","year":"2024","journal-title":"Exp Clin Transplant"},{"key":"10.1016\/j.trre.2025.100979_bb0490","article-title":"An uncommon presentation of cryptococcal meningoencephalitis","volume":"14","author":"Freitas","year":"2022","journal-title":"Cureus"},{"key":"10.1016\/j.trre.2025.100979_bb0495","doi-asserted-by":"crossref","DOI":"10.1590\/0074-02760180050","article-title":"Diagnostic and therapeutic strategies in cryptococcosis: impact on outcome","volume":"113","author":"Chammard","year":"2018","journal-title":"Mem Inst Oswaldo Cruz"},{"key":"10.1016\/j.trre.2025.100979_bb0500","doi-asserted-by":"crossref","first-page":"717","DOI":"10.1007\/s11046-021-00575-9","article-title":"Update on pulmonary cryptococcosis","volume":"186","author":"Yamamura","year":"2021","journal-title":"Mycopathologia"},{"key":"10.1016\/j.trre.2025.100979_bb0505","doi-asserted-by":"crossref","first-page":"e495","DOI":"10.1016\/S1473-3099(23)00731-4","article-title":"Global guideline for the diagnosis and management of cryptococcosis: an initiative of the ECMM and ISHAM in cooperation with the ASM","volume":"24","author":"Chang","year":"2024","journal-title":"Lancet Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0510","doi-asserted-by":"crossref","DOI":"10.1093\/ofid\/ofw167","article-title":"Pulmonary cryptococcosis in the immunocompetent patient-many questions, some answers","volume":"3","author":"Fisher","year":"2016","journal-title":"Open Forum Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0515","doi-asserted-by":"crossref","first-page":"110","DOI":"10.1111\/j.1439-0507.2011.02061.x","article-title":"Posaconazole: when and how? The clinician\u2019s view","volume":"55","author":"Katragkou","year":"2012","journal-title":"Mycoses"},{"key":"10.1016\/j.trre.2025.100979_bb0520","doi-asserted-by":"crossref","first-page":"539","DOI":"10.1097\/QCO.0000000000000315","article-title":"Repeated therapeutic lumbar punctures in cryptococcal meningitis - necessity and\/or opportunity?","volume":"29","author":"Chang","year":"2016","journal-title":"Curr Opin Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0525","doi-asserted-by":"crossref","first-page":"919","DOI":"10.1007\/s40265-013-0069-4","article-title":"Amphotericin B formulations: a comparative review of efficacy and toxicity","volume":"73","author":"Hamill","year":"2013","journal-title":"Drugs"},{"key":"10.1016\/j.trre.2025.100979_bb0530","doi-asserted-by":"crossref","first-page":"e1","DOI":"10.1093\/cid\/civ933","article-title":"Clinical practice guideline for the management of candidiasis: 2016 update by the infectious diseases Society of America","volume":"62","author":"Pappas","year":"2016","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0535","doi-asserted-by":"crossref","first-page":"941","DOI":"10.3892\/etm.2014.1534","article-title":"Evaluation of hypokalemia and potassium supplementation during administration of liposomal-amphotericin B","volume":"7","author":"Usami","year":"2014","journal-title":"Exp Ther Med"},{"key":"10.1016\/j.trre.2025.100979_bb0540","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1056\/NEJMoa1509024","article-title":"Adjunctive dexamethasone in HIV-associated cryptococcal meningitis","volume":"374","author":"Beardsley","year":"2016","journal-title":"N Engl J Med"},{"key":"10.1016\/j.trre.2025.100979_bb0545","doi-asserted-by":"crossref","first-page":"226","DOI":"10.4314\/ahs.v12i2.23","article-title":"Challenges in diagnosis and management of Cryptococcal immune reconstitution inflammatory syndrome (IRIS) in resource limited settings","volume":"12","author":"Musubire","year":"2012","journal-title":"Afr Health Sci"},{"key":"10.1016\/j.trre.2025.100979_bb0550","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1093\/cid\/ciu711","article-title":"Predictors of immune reconstitution syndrome in organ transplant recipients with cryptococcosis: implications for the management of immunosuppression","volume":"60","author":"Sun","year":"2015","journal-title":"Clin Infect Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0555","doi-asserted-by":"crossref","DOI":"10.1111\/ctr.13587","article-title":"Pneumocystis jiroveci in solid organ transplantation: guidelines from the American Society of Transplantation infectious diseases community of practice","volume":"33","author":"Fishman","year":"2019","journal-title":"Clin Transplant"},{"key":"10.1016\/j.trre.2025.100979_bb0560","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1007\/s12281-011-0064-8","article-title":"Cryptococcus-related immune reconstitution inflammatory syndrome(IRIS): pathogenesis and its clinical implications","volume":"5","author":"Wiesner","year":"2011","journal-title":"Curr Fungal Infect Rep"},{"key":"10.1016\/j.trre.2025.100979_bb0565","article-title":"Cryptococcal immune reconstitution inflammatory syndrome: from blood and cerebrospinal fluid biomarkers to treatment approaches","volume":"11","author":"Brienze","year":"2021","journal-title":"Life (Basel)"},{"key":"10.1016\/j.trre.2025.100979_bb0570","doi-asserted-by":"crossref","DOI":"10.1177\/20543581231172399","article-title":"Sequelae of cryptococcal-immune reconstitution inflammatory syndrome in a kidney transplant recipient: a case report","volume":"10","author":"Lasry","year":"2023","journal-title":"Can J Kidney Health Dis"},{"key":"10.1016\/j.trre.2025.100979_bb0575","doi-asserted-by":"crossref","DOI":"10.3390\/microorganisms10122419","article-title":"Cryptococcal immune reconstitution inflammatory syndrome: from clinical studies to animal experiments","volume":"10","author":"Shi","year":"2022","journal-title":"Microorganisms"},{"key":"10.1016\/j.trre.2025.100979_bb0580","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1016\/j.mmcr.2021.04.005","article-title":"Cryptococcus neoformans meningitis in kidney transplant recipients: a diagnostic and therapeutic challenge","volume":"32","author":"Gras","year":"2021","journal-title":"Med Mycol Case Rep"}],"container-title":["Transplantation Reviews"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955470X25000795?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0955470X25000795?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,1,6]],"date-time":"2026-01-06T11:39:46Z","timestamp":1767699586000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0955470X25000795"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1]]},"references-count":116,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,1]]}},"alternative-id":["S0955470X25000795"],"URL":"https:\/\/doi.org\/10.1016\/j.trre.2025.100979","relation":{},"ISSN":["0955-470X"],"issn-type":[{"value":"0955-470X","type":"print"}],"subject":[],"published":{"date-parts":[[2026,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Cryptococcosis in kidney transplant recipients: Pathogenesis, clinical challenges, and evolving therapeutic strategies","name":"articletitle","label":"Article Title"},{"value":"Transplantation Reviews","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trre.2025.100979","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2025 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"100979"}}