{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,25]],"date-time":"2026-03-25T19:23:22Z","timestamp":1774466602154,"version":"3.50.1"},"reference-count":34,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,5,1]],"date-time":"2016-05-01T00:00:00Z","timestamp":1462060800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Military Key Program","award":["BWS12J009"],"award-info":[{"award-number":["BWS12J009"]}]}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","translationalres.com","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Translational Research"],"published-print":{"date-parts":[[2016,5]]},"DOI":"10.1016\/j.trsl.2015.12.010","type":"journal-article","created":{"date-parts":[[2015,12,19]],"date-time":"2015-12-19T15:09:41Z","timestamp":1450537781000},"page":"38-51","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":14,"special_numbering":"C","title":["Autologous bone marrow stromal cell transplantation as a treatment for acute radiation enteritis induced by a moderate dose of radiation in dogs"],"prefix":"10.1016","volume":"171","author":[{"given":"Wenda","family":"Xu","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jiang","family":"Chen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xu","family":"Liu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hongyu","family":"Li","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xingshun","family":"Qi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaozhong","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.trsl.2015.12.010_bib1","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1089\/ars.2013.5652","article-title":"Stem cell therapies for the treatment of radiation-induced normal tissue side effects","volume":"21","author":"Benderitter","year":"2014","journal-title":"Antioxid Redox Signal"},{"key":"10.1016\/j.trsl.2015.12.010_bib2","doi-asserted-by":"crossref","first-page":"1011","DOI":"10.1038\/nm755","article-title":"Damaged epithelia regenerated by bone marrow-derived cells in the human gastrointestinal tract","volume":"8","author":"Okamoto","year":"2002","journal-title":"Nat Med"},{"key":"10.1016\/j.trsl.2015.12.010_bib3","doi-asserted-by":"crossref","first-page":"1984","DOI":"10.1053\/j.gastro.2005.03.028","article-title":"A regenerative role for bone marrow following experimental colitis: contribution to neovasculogenesis and myofibroblasts","volume":"128","author":"Brittan","year":"2005","journal-title":"Gastroenterology"},{"key":"10.1016\/j.trsl.2015.12.010_bib4","doi-asserted-by":"crossref","first-page":"330","DOI":"10.1016\/j.yexcr.2005.03.018","article-title":"Non-hematopoietic bone marrow stem cells: molecular control of expansion and differentiation","volume":"306","author":"Gregory","year":"2005","journal-title":"Exp Cell Res"},{"key":"10.1016\/j.trsl.2015.12.010_bib5","doi-asserted-by":"crossref","first-page":"1439","DOI":"10.1016\/S0140-6736(04)16104-7","article-title":"Treatment of severe acute graft-versus-host disease with third party haploidentical mesenchymal stem cells","volume":"363","author":"Le Blanc","year":"2004","journal-title":"Lancet"},{"key":"10.1016\/j.trsl.2015.12.010_bib6","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1038\/nm.1905","article-title":"Bone marrow stromal cells attenuate sepsis via prostaglandin E(2)-dependent reprogramming of host macrophages to increase their interleukin-10 production","volume":"15","author":"Nemeth","year":"2009","journal-title":"Nat Med"},{"key":"10.1016\/j.trsl.2015.12.010_bib7","doi-asserted-by":"crossref","first-page":"952","DOI":"10.1038\/cdd.2009.187","article-title":"Mesenchymal stem cells improve small intestinal integrity through regulation of endogenous epithelial cell homeostasis","volume":"17","author":"Semont","year":"2010","journal-title":"Cell Death Differ"},{"key":"10.1016\/j.trsl.2015.12.010_bib8","doi-asserted-by":"crossref","first-page":"1201","DOI":"10.1182\/blood-2008-07-170936","article-title":"Intravenous administration of mesenchymal stem cells genetically modified with extracellular superoxide dismutase improves survival in irradiated mice","volume":"113","author":"Abdel-Mageed","year":"2009","journal-title":"Blood"},{"key":"10.1016\/j.trsl.2015.12.010_bib9","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1007\/s11373-008-9256-9","article-title":"Effects of transplanted bone marrow mesenchymal stem cells on the irradiated intestine of mice","volume":"15","author":"Zhang","year":"2008","journal-title":"J Biomed Sci"},{"key":"10.1016\/j.trsl.2015.12.010_bib10","doi-asserted-by":"crossref","first-page":"e70170","DOI":"10.1371\/journal.pone.0070170","article-title":"Mesenchymal stem cell therapy stimulates endogenous host progenitor cells to improve colonic epithelial regeneration","volume":"8","author":"S\u00e9mont","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.trsl.2015.12.010_bib11","doi-asserted-by":"crossref","first-page":"916","DOI":"10.5966\/sctm.2013-0030","article-title":"A repeated autologous bone marrow-derived mesenchymal stem cell injections improve radiation-induced proctitis in pigs","volume":"2","author":"Linard","year":"2013","journal-title":"Stem Cells Transl Med"},{"key":"10.1016\/j.trsl.2015.12.010_bib12","doi-asserted-by":"crossref","first-page":"1543","DOI":"10.1177\/1535370214533884","article-title":"Acute radiation enteritis caused by dose-dependent radiation exposure in dogs: experimental research. Experimental biology and medicine","volume":"239","author":"Xu","year":"2014","journal-title":"Exp Biol Med (Maywood)"},{"issue":"5","key":"10.1016\/j.trsl.2015.12.010_bib13","doi-asserted-by":"crossref","first-page":"A-664","DOI":"10.1016\/S0016-5085(09)63062-6","article-title":"Mesenchymal stem cells administered via novel selective mesenteric artery cannulation for the treatment of severe refractory Crohn's disease","volume":"136","author":"Dinesen","year":"2009","journal-title":"Gastroenterology"},{"key":"10.1016\/j.trsl.2015.12.010_bib14","first-page":"1014","article-title":"In\u00a0vivo re-distribution of intra-coronary transplanted stem cells into beating and arrested hearts by magnetic resonance imaging in an acute myocardial infarction swine model","volume":"38","author":"Lu","year":"2010","journal-title":"Zhonghua Xin Xue Guan Bing Za Zhi"},{"key":"10.1016\/j.trsl.2015.12.010_bib15","first-page":"476","article-title":"Plasma D-lactate levels as a useful marker of increased intestinal permeability after severe injuries","volume":"12","author":"Sun","year":"2000","journal-title":"Zhong guo wei zhong bing ji jiu yi xue"},{"key":"10.1016\/j.trsl.2015.12.010_bib16","doi-asserted-by":"crossref","first-page":"e24072","DOI":"10.1371\/journal.pone.0024072","article-title":"Bone marrow stromal cell transplantation mitigates radiation-induced gastrointestinal syndrome in mice","volume":"6","author":"Saha","year":"2011","journal-title":"PLoS One"},{"key":"10.1016\/j.trsl.2015.12.010_bib17","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1152\/ajpheart.00186.2009","article-title":"Heart failure therapy mediated by the trophic activities of bone marrow mesenchymal stem cells: a non-invasive therapeutic regimen","volume":"296","author":"Shabbir","year":"2009","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.trsl.2015.12.010_bib18","doi-asserted-by":"crossref","first-page":"3597","DOI":"10.1073\/pnas.0611112104","article-title":"Brain protection using autologous bone marrow cell, metalloproteinase inhibitors, and metabolic treatment in cerebral ischemia","volume":"104","author":"Baker","year":"2007","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.trsl.2015.12.010_bib19","doi-asserted-by":"crossref","first-page":"399","DOI":"10.1359\/JBMR.041117","article-title":"Alveolar bone marrow as a cell source for regenerative medicine: differences between alveolar and lilac bone marrow stromal cells","volume":"20","author":"Matsubara","year":"2005","journal-title":"J Bone Miner Res"},{"key":"10.1016\/j.trsl.2015.12.010_bib20","doi-asserted-by":"crossref","first-page":"485","DOI":"10.1080\/14653240310003611","article-title":"Immunomodulatory effects of fetal and adult mesenchymal stem cells","volume":"5","author":"Le Blanc","year":"2003","journal-title":"Cytotherapy"},{"key":"10.1016\/j.trsl.2015.12.010_bib21","doi-asserted-by":"crossref","first-page":"480","DOI":"10.2307\/3577353","article-title":"Comparison of the gastrointestinal syndrome after total-body or total-abdominal irradiation","volume":"117","author":"Mason","year":"1989","journal-title":"Radiat Res"},{"key":"10.1016\/j.trsl.2015.12.010_bib22","doi-asserted-by":"crossref","first-page":"1962","DOI":"10.1002\/1097-0142(19881101)62:9<1962::AID-CNCR2820620916>3.0.CO;2-T","article-title":"Radiation proctitis in the rat sequential changes and effects of anti-inflammatory agents","volume":"62","author":"Northway","year":"1988","journal-title":"Cancer"},{"key":"10.1016\/j.trsl.2015.12.010_bib23","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1016\/S0022-3476(78)80138-3","article-title":"One-hour blood xylose test: a reliable index of small bowel function","volume":"90","author":"Buts","year":"1978","journal-title":"J Pediatr"},{"key":"10.1016\/j.trsl.2015.12.010_bib24","doi-asserted-by":"crossref","first-page":"149","DOI":"10.1097\/00042737-200012020-00010","article-title":"The effect of severe undernutrition, and subsequent refeeding on digestive function in human patients","volume":"12","author":"Winter","year":"2000","journal-title":"Eur J Gastroenterol Hepatol"},{"key":"10.1016\/j.trsl.2015.12.010_bib25","doi-asserted-by":"crossref","first-page":"1314","DOI":"10.1080\/003655200453683","article-title":"Gut permeability in patients with acute pancreatitis","volume":"35","author":"Juvonen","year":"2000","journal-title":"Scand J Gastroenterol"},{"key":"10.1016\/j.trsl.2015.12.010_bib26","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/0016-5085(81)90725-3","article-title":"Effect of intestinal ischemia on diamine oxidase activity in rat intestinal tissue and blood","volume":"80","author":"Wollin","year":"1981","journal-title":"Gastroenterology"},{"key":"10.1016\/j.trsl.2015.12.010_bib27","doi-asserted-by":"crossref","first-page":"1020","DOI":"10.1634\/stemcells.2005-0260","article-title":"Local irradiation not only induces homing of human mesenchymal stem cells at exposed sites but promotes their widespread engraftment to multiple organs: a study of their quantitative distribution after irradiation damage","volume":"24","author":"Francois","year":"2006","journal-title":"Stem Cells"},{"key":"10.1016\/j.trsl.2015.12.010_bib28","doi-asserted-by":"crossref","first-page":"1028","DOI":"10.1002\/jgm.452","article-title":"Mesenchymal stem cells home to injured tissues when co-infused with hematopoietic cells to treat a radiation-induced multi-organ failure syndrome","volume":"5","author":"Chapel","year":"2003","journal-title":"J Gene Med"},{"key":"10.1016\/j.trsl.2015.12.010_bib29","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1007\/978-0-387-34133-0_2","article-title":"Mesenchymal stem cells increase self-renewal of small intestinal epithelium and accelerate structural recovery after radiation injury","volume":"585","author":"S\u00e9mont","year":"2006","journal-title":"Adv Exp Med Biol"},{"key":"10.1016\/j.trsl.2015.12.010_bib30","doi-asserted-by":"crossref","first-page":"271","DOI":"10.1038\/srep00271","article-title":"Fusion of intestinal epithelial cells with bone marrow derived cells is dispensable for tissue homeostasis","volume":"2","author":"de Jong","year":"2012","journal-title":"Sci Rep"},{"key":"10.1016\/j.trsl.2015.12.010_bib31","doi-asserted-by":"crossref","first-page":"2397","DOI":"10.1073\/pnas.0437997100","article-title":"Differentiation, cell fusion, and nuclear fusion during ex\u00a0vivo repair of epithelium by human adult stem cells from bone marrow stroma","volume":"100","author":"Spees","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.trsl.2015.12.010_bib32","doi-asserted-by":"crossref","first-page":"e8014","DOI":"10.1371\/journal.pone.0008014","article-title":"Protective role of R-spondin1, an intestinal stem cell growth factor, against radiation-induced gastrointestinal syndrome in mice","volume":"4","author":"Bhanja","year":"2009","journal-title":"PLoS One"},{"key":"10.1016\/j.trsl.2015.12.010_bib33","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1002\/path.4590","article-title":"TH17 predominant T cell responses in radiation-induced bowel disease are modulated by treatment with adipose-derived mesenchymal stromal cells","volume":"237","author":"Bessout","year":"2015","journal-title":"J Pathol"},{"key":"10.1016\/j.trsl.2015.12.010_bib34","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1007\/s12016-012-8347-6","article-title":"Use of mesenchymal stem cells (MSC) in chronic inflammatory fistulizing and fibrotic diseases: a comprehensive review","volume":"45","author":"Voswinkel","year":"2013","journal-title":"Clin Rev Allergy Immunol"}],"container-title":["Translational Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524415004521?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524415004521?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,9,2]],"date-time":"2019-09-02T19:16:55Z","timestamp":1567451815000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1931524415004521"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,5]]},"references-count":34,"alternative-id":["S1931524415004521"],"URL":"https:\/\/doi.org\/10.1016\/j.trsl.2015.12.010","relation":{},"ISSN":["1931-5244"],"issn-type":[{"value":"1931-5244","type":"print"}],"subject":[],"published":{"date-parts":[[2016,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Autologous bone marrow stromal cell transplantation as a treatment for acute radiation enteritis induced by a moderate dose of radiation in dogs","name":"articletitle","label":"Article Title"},{"value":"Translational Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trsl.2015.12.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2016 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}