{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T03:01:29Z","timestamp":1777431689346,"version":"3.51.4"},"reference-count":83,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,6,1]],"date-time":"2017-06-01T00:00:00Z","timestamp":1496275200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","translationalres.com","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Translational Research"],"published-print":{"date-parts":[[2017,6]]},"DOI":"10.1016\/j.trsl.2017.03.003","type":"journal-article","created":{"date-parts":[[2017,3,23]],"date-time":"2017-03-23T07:15:19Z","timestamp":1490253319000},"page":"68-76","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":25,"special_numbering":"C","title":["Skin microbiome and mast cells"],"prefix":"10.1016","volume":"184","author":[{"given":"Satomi","family":"Igawa","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anna","family":"Di Nardo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.trsl.2017.03.003_bib1","doi-asserted-by":"crossref","first-page":"1351","DOI":"10.1172\/JCI0214704","article-title":"Differential responses of mast cell Toll-like receptors 2 and 4 in allergy and innate immunity","volume":"109","author":"Supajatura","year":"2002","journal-title":"J Clin Invest"},{"key":"10.1016\/j.trsl.2017.03.003_bib2","doi-asserted-by":"crossref","first-page":"190","DOI":"10.1111\/j.0105-2896.2005.00279.x","article-title":"Rapidly changing perspectives about mast cells at mucosal surfaces","volume":"206","author":"Vliagoftis","year":"2005","journal-title":"Immunol Rev"},{"key":"10.1016\/j.trsl.2017.03.003_bib3","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.ejphar.2015.06.034","article-title":"Microbes taming mast cells: Implications for allergic inflammation and beyond","volume":"778","author":"Forsythe","year":"2016","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.trsl.2017.03.003_bib4","doi-asserted-by":"crossref","first-page":"25","DOI":"10.1016\/j.immuni.2012.07.003","article-title":"Developmental origin and functional specialization of mast cell subsets","volume":"37","author":"Gurish","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.trsl.2017.03.003_bib5","doi-asserted-by":"crossref","first-page":"1003","DOI":"10.1084\/jem.175.4.1003","article-title":"Differential expression of secretory granule proteases in mouse mast cells exposed to interleukin 3 and c-kit ligand","volume":"175","author":"Gurish","year":"1992","journal-title":"J Exp Med"},{"key":"10.1016\/j.trsl.2017.03.003_bib6","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1111\/apm.1966.66.3.289","article-title":"Mast cells in rat gastrointestinal mucosa. I. Effects of fixation","volume":"66","author":"Enerback","year":"1966","journal-title":"Acta Pathol Microbiol Scand"},{"key":"10.1016\/j.trsl.2017.03.003_bib7","doi-asserted-by":"crossref","first-page":"303","DOI":"10.1111\/apm.1966.66.3.303","article-title":"Mast cells in rat gastrointestinal mucosa. 2. Dye-binding and metachromatic properties","volume":"66","author":"Enerback","year":"1966","journal-title":"Acta Pathol Microbiol Scand"},{"key":"10.1016\/j.trsl.2017.03.003_bib8","doi-asserted-by":"crossref","first-page":"4981","DOI":"10.1182\/blood-2010-01-257287","article-title":"Mast cell proteases: multifaceted regulators of inflammatory disease","volume":"115","author":"Pejler","year":"2010","journal-title":"Blood"},{"key":"10.1016\/j.trsl.2017.03.003_bib9","doi-asserted-by":"crossref","first-page":"151","DOI":"10.1016\/S1471-4906(01)02156-1","article-title":"The role of mast cells in host defense and their subversion by bacterial pathogens","volume":"23","author":"Feger","year":"2002","journal-title":"Trends Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib10","doi-asserted-by":"crossref","first-page":"e41234","DOI":"10.1371\/journal.pone.0041234","article-title":"Systemic effects of ingested Lactobacillus rhamnosus: inhibition of mast cell membrane potassium (IKCa) current and degranulation","volume":"7","author":"Forsythe","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.trsl.2017.03.003_bib11","first-page":"731","article-title":"Lactobacillus paracasei CNCM I-2116 (ST11) inhibits substance P-induced skin inflammation and accelerates skin barrier function recovery in\u00a0vitro","volume":"20","author":"Gueniche","year":"2010","journal-title":"Eur J Dermatol"},{"key":"10.1016\/j.trsl.2017.03.003_bib12","doi-asserted-by":"crossref","first-page":"1669","DOI":"10.1080\/09168451.2014.930327","article-title":"Commensal bacteria directly suppress in\u00a0vitro degranulation of mast cells in a MyD88-independent manner","volume":"78","author":"Kasakura","year":"2014","journal-title":"Biosci Biotechnol Biochem"},{"key":"10.1016\/j.trsl.2017.03.003_bib13","doi-asserted-by":"crossref","first-page":"941","DOI":"10.1016\/j.clinthera.2015.02.008","article-title":"Mast cell activation disease and microbiotic interactions","volume":"37","author":"Afrin","year":"2015","journal-title":"Clin Ther"},{"key":"10.1016\/j.trsl.2017.03.003_bib14","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1038\/jid.2011.417","article-title":"Skin microbiome: looking back to move forward","volume":"132","author":"Kong","year":"2012","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.trsl.2017.03.003_bib15","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1101\/gr.075549.107","article-title":"A diversity profile of the human skin microbiota","volume":"18","author":"Grice","year":"2008","journal-title":"Genome Res"},{"key":"10.1016\/j.trsl.2017.03.003_bib16","first-page":"546","article-title":"Mast cell-mediated inflammation in asthma","volume":"63","author":"Wasserman","year":"1989","journal-title":"Ann Allergy"},{"key":"10.1016\/j.trsl.2017.03.003_bib17","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1136\/thx.2008.101683","article-title":"Novel site-specific mast cell subpopulations in the human lung","volume":"64","author":"Andersson","year":"2009","journal-title":"Thorax"},{"key":"10.1016\/j.trsl.2017.03.003_bib18","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1136\/jcp.2004.017210","article-title":"Mast cell distribution in normal adult skin","volume":"58","author":"Janssens","year":"2005","journal-title":"J Clin Pathol"},{"key":"10.1016\/j.trsl.2017.03.003_bib19","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1152\/physrev.1997.77.4.1033","article-title":"Mast cells","volume":"77","author":"Metcalfe","year":"1997","journal-title":"Physiol Rev"},{"key":"10.1016\/j.trsl.2017.03.003_bib20","doi-asserted-by":"crossref","first-page":"444","DOI":"10.1038\/mi.2014.131","article-title":"Potential effector and immunoregulatory functions of mast cells in mucosal immunity","volume":"8","author":"Reber","year":"2015","journal-title":"Mucosal Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib21","doi-asserted-by":"crossref","first-page":"194","DOI":"10.1111\/cea.12675","article-title":"Mast cells in asthma\u2013state of the art","volume":"46","author":"Bradding","year":"2016","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.trsl.2017.03.003_bib22","doi-asserted-by":"crossref","first-page":"14210","DOI":"10.1073\/pnas.1111048108","article-title":"Protease phenotype of constitutive connective tissue and of induced mucosal mast cells in mice is regulated by the tissue","volume":"108","author":"Xing","year":"2011","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.trsl.2017.03.003_bib23","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1083\/jcb.135.1.279","article-title":"Mast cells that reside at different locations in the jejunum of mice infected with Trichinella spiralis exhibit sequential changes in their granule ultrastructure and chymase phenotype","volume":"135","author":"Friend","year":"1996","journal-title":"J Cell Biol"},{"key":"10.1016\/j.trsl.2017.03.003_bib24","doi-asserted-by":"crossref","first-page":"5537","DOI":"10.4049\/jimmunol.160.11.5537","article-title":"Reversible expression of tryptases and chymases in the jejunal mast cells of mice infected with Trichinella spiralis","volume":"160","author":"Friend","year":"1998","journal-title":"J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib25","doi-asserted-by":"crossref","first-page":"128","DOI":"10.1073\/pnas.91.1.128","article-title":"Strain-specific and tissue-specific expression of mouse mast cell secretory granule proteases","volume":"91","author":"Stevens","year":"1994","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.trsl.2017.03.003_bib26","doi-asserted-by":"crossref","first-page":"4464","DOI":"10.1073\/pnas.83.12.4464","article-title":"Two types of human mast cells that have distinct neutral protease compositions","volume":"83","author":"Irani","year":"1986","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.trsl.2017.03.003_bib27","doi-asserted-by":"crossref","first-page":"1579","DOI":"10.1016\/j.molimm.2005.09.019","article-title":"TLR3 activation inhibits human mast cell attachment to fibronectin and vitronectin","volume":"43","author":"Kulka","year":"2006","journal-title":"Mol Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib28","doi-asserted-by":"crossref","first-page":"e58","DOI":"10.1182\/blood-2013-02-483792","article-title":"Redefinition of the human mast cell transcriptome by deep-CAGE sequencing","volume":"123","author":"Motakis","year":"2014","journal-title":"Blood"},{"key":"10.1016\/j.trsl.2017.03.003_bib29","doi-asserted-by":"crossref","first-page":"1625","DOI":"10.4049\/jimmunol.170.4.1625","article-title":"Cutting edge: distinct Toll-like receptor 2 activators selectively induce different classes of mediator production from human mast cells","volume":"170","author":"McCurdy","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib30","doi-asserted-by":"crossref","first-page":"1046","DOI":"10.1016\/j.jaci.2010.03.003","article-title":"Accumulation of intraepithelial mast cells with a unique protease phenotype in T(H)2-high asthma","volume":"125","author":"Dougherty","year":"2010","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib31","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1016\/j.jaci.2013.02.011","article-title":"Human mast cells arise from a common circulating progenitor","volume":"132","author":"Maaninka","year":"2013","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib32","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/S0344-0338(11)80086-5","article-title":"Heterogeneity of mast cells at multiple body sites. Fluorescent determination of avidin binding and immunofluorescent determination of chymase, tryptase, and carboxypeptidase content","volume":"189","author":"Weidner","year":"1993","journal-title":"Pathol Res Pract"},{"key":"10.1016\/j.trsl.2017.03.003_bib33","doi-asserted-by":"crossref","first-page":"1374","DOI":"10.1046\/j.1523-1755.2001.0590041374.x","article-title":"Mast cell chymase expression and mast cell phenotypes in human rejected kidneys","volume":"59","author":"Yamada","year":"2001","journal-title":"Kidney Int"},{"key":"10.1016\/j.trsl.2017.03.003_bib34","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1038\/ni1158","article-title":"Mast cells in the development of adaptive immune responses","volume":"6","author":"Galli","year":"2005","journal-title":"Nat Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib35","doi-asserted-by":"crossref","first-page":"679","DOI":"10.1016\/j.coi.2009.09.007","article-title":"New roles for mast cells in modulating allergic reactions and immunity against pathogens","volume":"21","author":"Hofmann","year":"2009","journal-title":"Curr Opin Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib36","doi-asserted-by":"crossref","first-page":"787","DOI":"10.1038\/nri1460","article-title":"Mast-cell responses to pathogens","volume":"4","author":"Marshall","year":"2004","journal-title":"Nat Rev Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib37","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1016\/j.imbio.2007.10.017","article-title":"Mast cell functions in the innate skin immune system","volume":"213","author":"Metz","year":"2008","journal-title":"Immunobiology"},{"key":"10.1016\/j.trsl.2017.03.003_bib38","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1159\/000343895","article-title":"Expression and functional characterization of retinoic acid-inducible gene-I-like receptors of mast cells in response to viral infection","volume":"5","author":"Fukuda","year":"2013","journal-title":"J Innate Immun"},{"key":"10.1016\/j.trsl.2017.03.003_bib39","doi-asserted-by":"crossref","first-page":"4676","DOI":"10.4049\/jimmunol.1202096","article-title":"Inflammatory response of mast cells during influenza A virus infection is mediated by active infection and RIG-I signaling","volume":"190","author":"Graham","year":"2013","journal-title":"J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib40","doi-asserted-by":"crossref","first-page":"531","DOI":"10.4049\/jimmunol.173.1.531","article-title":"TLR3-, TLR7-, and TLR9-mediated production of proinflammatory cytokines and chemokines from murine connective tissue type skin-derived mast cells but not from bone marrow-derived mast cells","volume":"173","author":"Matsushima","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib41","doi-asserted-by":"crossref","first-page":"899","DOI":"10.1002\/eji.200323830","article-title":"Toll-like receptor 2 (TLR2) and TLR4 differentially activate human mast cells","volume":"33","author":"Varadaradjalou","year":"2003","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib42","doi-asserted-by":"crossref","first-page":"978","DOI":"10.1182\/blood-2004-07-2656","article-title":"TLR3-induced activation of mast cells modulates CD8+ T-cell recruitment","volume":"106","author":"Orinska","year":"2005","journal-title":"Blood"},{"key":"10.1016\/j.trsl.2017.03.003_bib43","doi-asserted-by":"crossref","first-page":"345","DOI":"10.4049\/jimmunol.1101703","article-title":"Skin mast cells protect mice against vaccinia virus by triggering mast cell receptor S1PR2 and releasing antimicrobial peptides","volume":"188","author":"Wang","year":"2012","journal-title":"J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib44","doi-asserted-by":"crossref","first-page":"434","DOI":"10.1002\/eji.200636379","article-title":"Antimicrobial peptides human beta-defensin (hBD)-3 and hBD-4 activate mast cells and increase skin vascular permeability","volume":"37","author":"Chen","year":"2007","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib45","doi-asserted-by":"crossref","first-page":"2274","DOI":"10.4049\/jimmunol.170.5.2274","article-title":"Cutting edge: mast cell antimicrobial activity is mediated by expression of cathelicidin antimicrobial peptide","volume":"170","author":"Di Nardo","year":"2003","journal-title":"J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib46","doi-asserted-by":"crossref","first-page":"1771","DOI":"10.1021\/bi0620297","article-title":"Structure and mechanism of action of the antimicrobial peptide piscidin","volume":"46","author":"Campagna","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.trsl.2017.03.003_bib47","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1159\/000218115","article-title":"NF-kappaB-dependent induction of cathelicidin-related antimicrobial peptide in murine mast cells by lipopolysaccharide","volume":"150","author":"Li","year":"2009","journal-title":"Int Arch Allergy Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib48","doi-asserted-by":"crossref","first-page":"7565","DOI":"10.4049\/jimmunol.180.11.7565","article-title":"Mast cell cathelicidin antimicrobial peptide prevents invasive group A Streptococcus infection of the skin","volume":"180","author":"Di Nardo","year":"2008","journal-title":"J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib49","doi-asserted-by":"crossref","first-page":"3070","DOI":"10.1182\/blood-2007-07-104018","article-title":"Phagocytosis-independent antimicrobial activity of mast cells by means of extracellular trap formation","volume":"111","author":"von Kockritz-Blickwede","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.trsl.2017.03.003_bib50","doi-asserted-by":"crossref","first-page":"614","DOI":"10.1038\/270614a0","article-title":"Histamine release from rat mast cells induced by Sendai virus","volume":"270","author":"Sugiyama","year":"1977","journal-title":"Nature"},{"key":"10.1016\/j.trsl.2017.03.003_bib51","doi-asserted-by":"crossref","first-page":"491","DOI":"10.1016\/0008-8749(84)90404-0","article-title":"The role of mast cells in virus-induced inflammation in the murine central nervous system","volume":"86","author":"Mokhtarian","year":"1984","journal-title":"Cell Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib52","doi-asserted-by":"crossref","first-page":"197","DOI":"10.3109\/01902149509068827","article-title":"Virus-induced increases in airway mast cells in brown Norway rats are associated with enhanced pulmonary viral replication and persisting lymphocytic infiltration","volume":"21","author":"Sorden","year":"1995","journal-title":"Exp Lung Res"},{"key":"10.1016\/j.trsl.2017.03.003_bib53","doi-asserted-by":"crossref","first-page":"7146","DOI":"10.1128\/JVI.74.15.7146-7150.2000","article-title":"Release of vasoactive cytokines by antibody-enhanced dengue virus infection of a human mast cell\/basophil line","volume":"74","author":"King","year":"2000","journal-title":"J Virol"},{"key":"10.1016\/j.trsl.2017.03.003_bib54","doi-asserted-by":"crossref","first-page":"71","DOI":"10.1189\/jlb.0308167","article-title":"Dramatic caspase-dependent apoptosis in antibody-enhanced dengue virus infection of human mast cells","volume":"85","author":"Brown","year":"2009","journal-title":"J Leukoc Biol"},{"key":"10.1016\/j.trsl.2017.03.003_bib55","doi-asserted-by":"crossref","first-page":"5467","DOI":"10.1182\/blood-2007-10-118547","article-title":"Human mast cell activation with virus-associated stimuli leads to the selective chemotaxis of natural killer cells by a CXCL8-dependent mechanism","volume":"111","author":"Burke","year":"2008","journal-title":"Blood"},{"key":"10.1016\/j.trsl.2017.03.003_bib56","doi-asserted-by":"crossref","first-page":"338","DOI":"10.1111\/j.1365-2885.1988.tb00193.x","article-title":"Parainfluenza-3 virus-induced enhancement of histamine release from calf lung mast cells\u2013effect of levamisole","volume":"11","author":"Ogunbiyi","year":"1988","journal-title":"J Vet Pharmacol Ther"},{"key":"10.1016\/j.trsl.2017.03.003_bib57","doi-asserted-by":"crossref","first-page":"554","DOI":"10.3382\/ps.2008-00468","article-title":"Evidence for a role of mast cells in the mucosal injury induced by Newcastle disease virus","volume":"88","author":"Sun","year":"2009","journal-title":"Poult Sci"},{"key":"10.1016\/j.trsl.2017.03.003_bib58","doi-asserted-by":"crossref","first-page":"2170","DOI":"10.1038\/jid.2013.150","article-title":"Mast cells play a key role in host defense against herpes simplex virus infection through TNF-alpha and IL-6 production","volume":"133","author":"Aoki","year":"2013","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.trsl.2017.03.003_bib59","doi-asserted-by":"crossref","first-page":"1315","DOI":"10.1073\/pnas.0308057100","article-title":"Herpes simplex virus 1 interaction with Toll-like receptor 2 contributes to lethal encephalitis","volume":"101","author":"Kurt-Jones","year":"2004","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.trsl.2017.03.003_bib60","doi-asserted-by":"crossref","first-page":"619","DOI":"10.1182\/blood-2006-06-027136","article-title":"Innate immunity against vaccinia virus is mediated by TLR2 and requires TLR-independent production of IFN-beta","volume":"109","author":"Zhu","year":"2007","journal-title":"Blood"},{"key":"10.1016\/j.trsl.2017.03.003_bib61","doi-asserted-by":"crossref","first-page":"1551","DOI":"10.4049\/jimmunol.1200471","article-title":"Commensal bacteria lipoteichoic acid increases skin mast cell antimicrobial activity against vaccinia viruses","volume":"189","author":"Wang","year":"2012","journal-title":"J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib62","doi-asserted-by":"crossref","first-page":"789","DOI":"10.1111\/j.1365-2222.2008.02964.x","article-title":"Severe atopic dermatitis is associated with a high burden of environmental Staphylococcus aureus","volume":"38","author":"Leung","year":"2008","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.trsl.2017.03.003_bib63","doi-asserted-by":"crossref","first-page":"850","DOI":"10.1101\/gr.131029.111","article-title":"Temporal shifts in the skin microbiome associated with disease flares and treatment in children with atopic dermatitis","volume":"22","author":"Kong","year":"2012","journal-title":"Genome Res"},{"key":"10.1016\/j.trsl.2017.03.003_bib64","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1111\/j.1365-2222.2005.02190.x","article-title":"Percutaneous application of peptidoglycan from Staphylococcus aureus induces an increase in mast cell numbers in the dermis of mice","volume":"35","author":"Matsui","year":"2005","journal-title":"Clin Exp Allergy"},{"key":"10.1016\/j.trsl.2017.03.003_bib65","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1038\/nature12655","article-title":"Staphylococcus delta-toxin induces allergic skin disease by activating mast cells","volume":"503","author":"Nakamura","year":"2013","journal-title":"Nature"},{"key":"10.1016\/j.trsl.2017.03.003_bib66","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.tips.2007.07.002","article-title":"Liaisons dangereuses: P2X(7) and the inflammasome","volume":"28","author":"Di Virgilio","year":"2007","journal-title":"Trends Pharmacol Sci"},{"key":"10.1016\/j.trsl.2017.03.003_bib67","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1038\/ncomms2023","article-title":"Extracellular ATP mediates mast cell-dependent intestinal inflammation through P2X7 purinoceptors","volume":"3","author":"Kurashima","year":"2012","journal-title":"Nat Commun"},{"key":"10.1016\/j.trsl.2017.03.003_bib68","doi-asserted-by":"crossref","first-page":"3970","DOI":"10.4049\/jimmunol.156.10.3970","article-title":"Extracellular ATP activates mast cells via a mechanism that is different from the activation induced by the cross-linking of Fc receptors","volume":"156","author":"Sudo","year":"1996","journal-title":"J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib69","doi-asserted-by":"crossref","first-page":"4987","DOI":"10.4049\/jimmunol.172.8.4987","article-title":"A novel P2X7 receptor activator, the human cathelicidin-derived peptide LL37, induces IL-1 beta processing and release","volume":"172","author":"Elssner","year":"2004","journal-title":"J Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib70","doi-asserted-by":"crossref","first-page":"530","DOI":"10.1016\/j.immuni.2014.01.014","article-title":"The enzyme Cyp26b1 mediates inhibition of mast cell activation by fibroblasts to maintain skin-barrier homeostasis","volume":"40","author":"Kurashima","year":"2014","journal-title":"Immunity"},{"key":"10.1016\/j.trsl.2017.03.003_bib71","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1001\/archdermatol.2010.413","article-title":"Neurogenic rosacea: a distinct clinical subtype requiring a modified approach to treatment","volume":"147","author":"Scharschmidt","year":"2011","journal-title":"Arch Dermatol"},{"key":"10.1016\/j.trsl.2017.03.003_bib72","doi-asserted-by":"crossref","first-page":"975","DOI":"10.1038\/nm1616","article-title":"Increased serine protease activity and cathelicidin promotes skin inflammation in rosacea","volume":"13","author":"Yamasaki","year":"2007","journal-title":"Nat Med"},{"key":"10.1016\/j.trsl.2017.03.003_bib73","doi-asserted-by":"crossref","first-page":"688","DOI":"10.1038\/jid.2010.351","article-title":"TLR2 expression is increased in rosacea and stimulates enhanced serine protease production by keratinocytes","volume":"131","author":"Yamasaki","year":"2011","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.trsl.2017.03.003_bib74","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/j.jaad.2013.08.006","article-title":"Potential role of microorganisms in the pathogenesis of rosacea","volume":"69","author":"Holmes","year":"2013","journal-title":"J Am Acad Dermatol"},{"key":"10.1016\/j.trsl.2017.03.003_bib75","doi-asserted-by":"crossref","first-page":"2728","DOI":"10.1038\/jid.2014.222","article-title":"Mast cells are key mediators of cathelicidin-initiated skin inflammation in rosacea","volume":"134","author":"Muto","year":"2014","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.trsl.2017.03.003_bib76","doi-asserted-by":"crossref","first-page":"1435","DOI":"10.1038\/jid.2012.14","article-title":"Doxycycline indirectly inhibits proteolytic activation of tryptic kallikrein-related peptidases and activation of cathelicidin","volume":"132","author":"Kanada","year":"2012","journal-title":"J Invest Dermatol"},{"key":"10.1016\/j.trsl.2017.03.003_bib77","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1038\/ng756","article-title":"Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome","volume":"29","author":"Hoffman","year":"2001","journal-title":"Nat Genet"},{"key":"10.1016\/j.trsl.2017.03.003_bib78","doi-asserted-by":"crossref","first-page":"481","DOI":"10.1038\/ncprheum0874","article-title":"Cryopyrinopathies: update on pathogenesis and treatment","volume":"4","author":"Neven","year":"2008","journal-title":"Nat Clin Pract Rheumatol"},{"key":"10.1016\/j.trsl.2017.03.003_bib79","doi-asserted-by":"crossref","first-page":"325","DOI":"10.1038\/ni.2231","article-title":"Sensing and reacting to microbes through the inflammasomes","volume":"13","author":"Franchi","year":"2012","journal-title":"Nat Immunol"},{"key":"10.1016\/j.trsl.2017.03.003_bib80","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1016\/j.immuni.2012.04.013","article-title":"Critical role for mast cells in interleukin-1 beta-driven skin inflammation associated with an activating mutation in the nlrp3 protein","volume":"37","author":"Nakamura","year":"2012","journal-title":"Immunity"},{"key":"10.1016\/j.trsl.2017.03.003_bib81","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1007\/s00281-014-0452-6","article-title":"Commensal bacteria and cutaneous immunity","volume":"37","author":"Nakamizo","year":"2015","journal-title":"Semin Immunopathol"},{"key":"10.1016\/j.trsl.2017.03.003_bib82","doi-asserted-by":"crossref","first-page":"1377","DOI":"10.1038\/nm.2062","article-title":"Commensal bacteria regulate Toll-like receptor 3-dependent inflammation after skin injury","volume":"15","author":"Lai","year":"2009","journal-title":"Nat Med"},{"key":"10.1016\/j.trsl.2017.03.003_bib83","doi-asserted-by":"crossref","first-page":"1205","DOI":"10.1016\/j.jaci.2016.09.019","article-title":"Skin microbiome promotes mast cell maturation by triggering stem cell factor (SCF) production in keratinocytes","volume":"139","author":"Wang","year":"2017","journal-title":"J Allergy Clin Immunol"}],"container-title":["Translational Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524416302523?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524416302523?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,22]],"date-time":"2023-08-22T19:41:50Z","timestamp":1692733310000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1931524416302523"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,6]]},"references-count":83,"alternative-id":["S1931524416302523"],"URL":"https:\/\/doi.org\/10.1016\/j.trsl.2017.03.003","relation":{},"ISSN":["1931-5244"],"issn-type":[{"value":"1931-5244","type":"print"}],"subject":[],"published":{"date-parts":[[2017,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Skin microbiome and mast cells","name":"articletitle","label":"Article Title"},{"value":"Translational Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trsl.2017.03.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}