{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,13]],"date-time":"2026-10-13T12:40:26Z","timestamp":1791895226805,"version":"4.3.4"},"reference-count":54,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T00:00:00Z","timestamp":1567296000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["5F31HL142313"],"award-info":[{"award-number":["5F31HL142313"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000050","name":"National Heart, Lung, and Blood Institute","doi-asserted-by":"publisher","award":["5T32HL007741"],"award-info":[{"award-number":["5T32HL007741"]}],"id":[{"id":"10.13039\/100000050","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006975","name":"Indiana Clinical and Translational Sciences Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100006975","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["UL1TR002494"],"award-info":[{"award-number":["UL1TR002494"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100006108","name":"National Center for Advancing Translational Sciences","doi-asserted-by":"publisher","award":["T32"],"award-info":[{"award-number":["T32"]}],"id":[{"id":"10.13039\/100006108","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","translationalres.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Translational Research"],"published-print":{"date-parts":[[2019,9]]},"DOI":"10.1016\/j.trsl.2019.05.001","type":"journal-article","created":{"date-parts":[[2019,5,14]],"date-time":"2019-05-14T11:51:46Z","timestamp":1557834706000},"page":"19-34","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":75,"special_numbering":"C","title":["3D bioprinting for lungs and hollow organs"],"prefix":"10.1016","volume":"211","author":[{"given":"Zachary","family":"Galliger","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2164-2024","authenticated-orcid":false,"given":"Caleb D.","family":"Vogt","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1802-1785","authenticated-orcid":false,"given":"Angela","family":"Panoskaltsis-Mortari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.trsl.2019.05.001_bib0001","doi-asserted-by":"crossref","first-page":"1331","DOI":"10.3390\/app7121331","article-title":"A bibliometric study to assess bioprinting evolution","volume":"7","author":"Naveau","year":"2017","journal-title":"Appl Sci"},{"key":"10.1016\/j.trsl.2019.05.001_bib0002","first-page":"144","article-title":"3D bioprinting for biomedical devices and tissue engineering: a review of recent trends and advances","volume":"3","author":"Derakhshanfar","year":"2018","journal-title":"Bioact Mater"},{"key":"10.1016\/j.trsl.2019.05.001_bib0003","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.gendis.2017.10.002","article-title":"3-D bioprinting technologies in tissue engineering and regenerative medicine: current and future trends","volume":"4","author":"Bishop","year":"2017","journal-title":"Genes Dis"},{"key":"10.1016\/j.trsl.2019.05.001_bib0004","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1016\/j.tibtech.2012.10.005","article-title":"Bioprinting for stem cell research","volume":"31","author":"Tasoglu","year":"2013","journal-title":"Trends Biotechnol"},{"key":"10.1016\/j.trsl.2019.05.001_bib0005","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1089\/ten.tea.2009.0659","article-title":"Development of a decellularized lung bioreactor system for bioengineering the lung: the matrix reloaded","volume":"16","author":"Price","year":"2010","journal-title":"Tissue Eng Part A"},{"key":"10.1016\/j.trsl.2019.05.001_bib0006","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1016\/j.healun.2013.10.030","article-title":"Perfusion decellularization of human and porcine lungs\u202f: bringing the matrix to clinical scale","volume":"33","author":"Gilpin","year":"2014","journal-title":"J Hear Lung Transplant"},{"key":"10.1016\/j.trsl.2019.05.001_bib0007","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1159\/000324896","article-title":"Matrix composition and mechanics of decellularized lung scaffolds","volume":"195","author":"Petersen","year":"2012","journal-title":"Cells Tissues Organs"},{"key":"10.1016\/j.trsl.2019.05.001_bib0008","doi-asserted-by":"crossref","first-page":"2437","DOI":"10.1089\/ten.tea.2011.0594","article-title":"A nonhuman primate model of lung regeneration: detergent-mediated decellularization and initial in vitro recellularization with mesenchymal stem cells","volume":"18","author":"Bonvillain","year":"2012","journal-title":"Tissue Eng Part A"},{"key":"10.1016\/j.trsl.2019.05.001_bib0009","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1038\/nm.2193","article-title":"Regeneration and orthotopic transplantation of a bioartificial lung","volume":"16","author":"Ott","year":"2010","journal-title":"Nat Med"},{"key":"10.1016\/j.trsl.2019.05.001_bib0010","series-title":"Pulmonary Physiology","article-title":"Chapter 1. Function and Structure of the Respiratory System","author":"Levitzky","year":"2013"},{"key":"10.1016\/j.trsl.2019.05.001_bib0011","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1164\/rccm.200308-1107OC","article-title":"The number of alveoli in the human lung","volume":"169","author":"Ochs","year":"2004","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.trsl.2019.05.001_bib0012","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1155\/2013\/101597","article-title":"Development and remodeling of the vertebrate blood-gas barrier","volume":"2013","author":"Makanya","year":"2013","journal-title":"Biomed Res Int"},{"key":"10.1016\/j.trsl.2019.05.001_bib0013","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1152\/jappl.1994.77.3.1060","article-title":"Alveolar septal structure in different species","volume":"77","author":"Mercer","year":"1994","journal-title":"J Appl Physiol"},{"key":"10.1016\/j.trsl.2019.05.001_bib0014","series-title":"The Pulmonary Epithelium in Health and Disease","first-page":"1","article-title":"Pulmonary epithelium: cell types and functions","author":"Chang","year":"2008"},{"key":"10.1016\/j.trsl.2019.05.001_bib0015","doi-asserted-by":"crossref","first-page":"32","DOI":"10.1148\/rg.351140089","article-title":"Bronchial arteries: anatomy, function, hypertrophy, and anomalies","volume":"35","author":"Walker","year":"2015","journal-title":"RadioGraphics"},{"key":"10.1016\/j.trsl.2019.05.001_bib0016","series-title":"Clinical Respiratory Medicine","first-page":"29","article-title":"Pulmonary circulation","author":"Culver","year":"2012"},{"key":"10.1016\/j.trsl.2019.05.001_bib0017","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.actbio.2017.01.035","article-title":"Bioprinting for vascular and vascularized tissue biofabrication","volume":"51","author":"Datta","year":"2017","journal-title":"Acta Biomater"},{"issue":"3","key":"10.1016\/j.trsl.2019.05.001_bib0018","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1097\/00005382-199522000-00003","article-title":"Imaging of the normal trachea","volume":"10","author":"Holbert","year":"1995","journal-title":"J Thorac Imaging"},{"key":"10.1016\/j.trsl.2019.05.001_bib0019","first-page":"349","article-title":"Visceral cartilage","volume":"122","author":"Reid","year":"1976","journal-title":"J Anat"},{"key":"10.1016\/j.trsl.2019.05.001_bib0020","doi-asserted-by":"crossref","first-page":"S72","DOI":"10.1016\/j.jaci.2009.08.048","article-title":"Anatomy, pathology, and physiology of the tracheobronchial tree: emphasis on the distal airways","volume":"124","author":"Hyde","year":"2009","journal-title":"J Allergy Clin Immunol"},{"key":"10.1016\/j.trsl.2019.05.001_bib0021","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1016\/j.ijporl.2018.11.010","article-title":"A 3-dimensional bioprinted tracheal segment implant pilot study: rabbit tracheal resection with graft implantation","volume":"117","author":"Kaye","year":"2019","journal-title":"Int J Pediatr Otorhinolaryngol"},{"key":"10.1016\/j.trsl.2019.05.001_bib0022","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1016\/j.joca.2009.08.009","article-title":"Review evaluation of histological scoring systems for tissue-engineered, repaired and osteoarthritic cartilage","volume":"18","author":"Rutgers","year":"2010","journal-title":"Osteoarthr Cartil"},{"key":"10.1016\/j.trsl.2019.05.001_bib0023","doi-asserted-by":"crossref","first-page":"1624","DOI":"10.3390\/ijms19061624","article-title":"3D bioprinted artificial trachea with epithelial cells and chondrogenic-differentiated bone marrow-derived mesenchymal stem cells","volume":"19","author":"Bae","year":"2018","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.trsl.2019.05.001_bib0024","doi-asserted-by":"crossref","first-page":"2103","DOI":"10.1038\/s41598-019-38565-z","article-title":"Experimental tracheal replacement using 3-dimensional bioprinted artificial trachea with autologous epithelial cells and chondrocytes","volume":"9","author":"Park","year":"2019","journal-title":"Sci Rep"},{"key":"10.1016\/j.trsl.2019.05.001_bib0025","doi-asserted-by":"crossref","first-page":"745","DOI":"10.1093\/icvts\/ivx444","article-title":"Scaffold-free trachea regeneration by tissue engineering with bio-3D printing\u2020","volume":"26","author":"Taniguchi","year":"2018","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"10.1016\/j.trsl.2019.05.001_bib0026","doi-asserted-by":"crossref","DOI":"10.1002\/adhm.201800983","article-title":"Replacement of rat tracheas by layered, trachea-like, scaffold-free structures of human cells using a bio-3D printing system","author":"Machino","year":"2019","journal-title":"Adv Healthc Mater"},{"key":"10.1016\/j.trsl.2019.05.001_bib0027","doi-asserted-by":"crossref","DOI":"10.1126\/sciadv.1500758","article-title":"Three-dimensional printing of complex biological structures by freeform reversible embedding of suspended hydrogels","volume":"1","author":"Hinton","year":"2015","journal-title":"Sci Adv"},{"key":"10.1016\/j.trsl.2019.05.001_bib0028","doi-asserted-by":"crossref","first-page":"106","DOI":"10.1016\/j.biomaterials.2015.05.008","article-title":"A novel tissue-engineered trachea with a mechanical behavior similar to native trachea","volume":"62","author":"Park","year":"2015","journal-title":"Biomaterials"},{"key":"10.1016\/j.trsl.2019.05.001_bib0029","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.actbio.2015.07.014","article-title":"Human turbinate mesenchymal stromal cell sheets with bellows graft for rapid tracheal epithelial regeneration","volume":"25","author":"Park","year":"2015","journal-title":"Acta Biomater"},{"key":"10.1016\/j.trsl.2019.05.001_bib0030","doi-asserted-by":"crossref","first-page":"1001","DOI":"10.1177\/0194599815605492","article-title":"Introducing a 3-dimensionally printed, tissue-engineered graft for airway reconstruction","volume":"153","author":"Goldstein","year":"2015","journal-title":"Otolaryngol Neck Surg"},{"key":"10.1016\/j.trsl.2019.05.001_bib0031","doi-asserted-by":"crossref","first-page":"998","DOI":"10.1016\/j.athoracsur.2017.03.051","article-title":"Three-dimensional-printed bioengineered tracheal grafts: preclinical results and potential for human use","volume":"104","author":"Rehmani","year":"2017","journal-title":"Ann Thorac Surg"},{"key":"10.1016\/j.trsl.2019.05.001_bib0032","doi-asserted-by":"crossref","first-page":"1301","DOI":"10.1089\/ten.tea.2017.0437","article-title":"Reinforced electrospun polycaprolactone nanofibers for tracheal repair in an in vivo ovine model","volume":"24","author":"Townsend","year":"2018","journal-title":"Tissue Eng Part A"},{"key":"10.1016\/j.trsl.2019.05.001_bib0033","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.cobme.2017.02.004","article-title":"3D bioprinting from the micrometer to millimeter length scales: Size does matter","volume":"1","author":"Hinton","year":"2017","journal-title":"Curr Opin Biomed Eng"},{"key":"10.1016\/j.trsl.2019.05.001_bib0034","doi-asserted-by":"crossref","first-page":"7974","DOI":"10.1038\/srep07974","article-title":"Engineering an in vitro air-blood barrier by 3D bioprinting","volume":"5","author":"Horv\u00e1th","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.trsl.2019.05.001_bib0035","doi-asserted-by":"crossref","first-page":"5399","DOI":"10.1073\/pnas.1815208116","article-title":"Renal reabsorption in 3D vascularized proximal tubule models","volume":"116","author":"Lin","year":"2019","journal-title":"Proc Natl Acad Sci"},{"key":"10.1016\/j.trsl.2019.05.001_bib0036","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1126\/science.aav9750","article-title":"Functional intravascular topologies and multivascular networks within biocompatible hydrogels","volume":"464","author":"Grigoryan","year":"2019","journal-title":"Science"},{"key":"10.1016\/j.trsl.2019.05.001_bib0037","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1039\/C5BM00034C","article-title":"In vitro model alveoli from photodegradable microsphere templates","volume":"3","author":"Lewis","year":"2015","journal-title":"Biomater Sci"},{"key":"10.1016\/j.trsl.2019.05.001_bib0038","doi-asserted-by":"crossref","first-page":"406","DOI":"10.1016\/j.ejrad.2008.09.002","article-title":"Observation of normal appearance and wall thickness of esophagus on CT images","volume":"72","author":"Xia","year":"2019","journal-title":"Eur J Radiol"},{"key":"10.1016\/j.trsl.2019.05.001_bib0039","doi-asserted-by":"crossref","first-page":"712","DOI":"10.1093\/icvts\/ivw048","article-title":"Tissue-engineered artificial oesophagus patch using three-dimensionally printed polycaprolactone with mesenchymal stem cells: a preliminary report","volume":"22","author":"Park","year":"2016","journal-title":"Interact Cardiovasc Thorac Surg"},{"key":"10.1016\/j.trsl.2019.05.001_bib0040","doi-asserted-by":"crossref","first-page":"2173","DOI":"10.1002\/sctm.17-0129","article-title":"Concise review: multifaceted characterization of human mesenchymal stem cells for use in regenerative medicine","volume":"6","author":"Samsonraj","year":"2017","journal-title":"Stem Cells Transl Med"},{"key":"10.1016\/j.trsl.2019.05.001_bib0041","doi-asserted-by":"crossref","first-page":"885","DOI":"10.1080\/21691401.2018.1439039","article-title":"Development of an omentum-cultured oesophageal scaffold reinforced by a 3D-printed ring: feasibility of an in vivo bioreactor","volume":"46","author":"Chung","year":"2018","journal-title":"Artif Cells, Nanomed Biotechnol"},{"key":"10.1016\/j.trsl.2019.05.001_bib0042","doi-asserted-by":"crossref","first-page":"5997","DOI":"10.1016\/j.actbio.2012.12.031","article-title":"Improved osteoblast cell affinity on plasma-modified 3-D extruded PCL scaffolds","volume":"9","author":"Domingos","year":"2013","journal-title":"Acta Biomater"},{"key":"10.1016\/j.trsl.2019.05.001_bib0043","doi-asserted-by":"crossref","first-page":"2962","DOI":"10.1016\/j.biomaterials.2006.01.011","article-title":"Peptide-surface modification of poly(caprolactone) with laminin-derived sequences for adipose-derived stem cell applications","volume":"27","author":"Santiago","year":"2006","journal-title":"Biomaterials"},{"key":"10.1016\/j.trsl.2019.05.001_bib0044","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/j.isci.2018.03.015","article-title":"Bioprinted 3D primary human intestinal tissues model aspects of native physiology and ADME\/Tox functions","volume":"2","author":"Madden","year":"2018","journal-title":"iScience"},{"key":"10.1016\/j.trsl.2019.05.001_bib0045","doi-asserted-by":"crossref","first-page":"035010","DOI":"10.1088\/1758-5090\/aac902","article-title":"Tailoring nanostructure and bioactivity of 3d-printable hydrogels with self-assemble peptides amphiphile (pa) for promoting bile duct formation","volume":"10","author":"Yan","year":"2018","journal-title":"Biofabrication"},{"key":"10.1016\/j.trsl.2019.05.001_bib0046","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1115\/1.3168367","article-title":"Flow of urine through the ureter: a collapsible, muscular tube undergoing peristalsis","volume":"111","author":"Griffiths","year":"1989","journal-title":"J Biomech Eng"},{"key":"10.1016\/j.trsl.2019.05.001_bib0047","doi-asserted-by":"crossref","first-page":"1018","DOI":"10.2478\/s11756-012-0090-1","article-title":"Options for histological study of the structure and ultrastructure of human urinary bladder epithelium","volume":"67","author":"Pol\u00e1k","year":"2012","journal-title":"Biologia (Bratisl)"},{"key":"10.1016\/j.trsl.2019.05.001_bib0048","series-title":"Netter's Essential Histology","first-page":"357","author":"Ovalle","year":"2013"},{"key":"10.1016\/j.trsl.2019.05.001_bib0049","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1016\/j.addr.2014.11.013","article-title":"Bladder tissue engineering: a literature review","volume":"82\u201383","author":"Lam Van Ba","year":"2015","journal-title":"Adv Drug Deliv Rev"},{"key":"10.1016\/j.trsl.2019.05.001_bib0050","doi-asserted-by":"crossref","first-page":"1035","DOI":"10.1016\/j.juro.2014.03.116","article-title":"Tissue engineering of the bladder\u2013reality or myth? A systematic review","volume":"192","author":"Sloff","year":"2014","journal-title":"J Urol"},{"key":"10.1016\/j.trsl.2019.05.001_bib0051","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/j.actbio.2016.12.008","article-title":"3D bioprinting of urethra with PCL\/PLCL blend and dual autologous cells in fibrin hydrogel: an in vitro evaluation of biomimetic mechanical property and cell growth environment","volume":"50","author":"Zhang","year":"2017","journal-title":"Acta Biomater"},{"key":"10.1016\/j.trsl.2019.05.001_bib0052","article-title":"Digitally tunable microfluidic bioprinting of multilayered cannular tissues","volume":"30","author":"Pi","year":"2018","journal-title":"Adv Mater"},{"key":"10.1016\/j.trsl.2019.05.001_bib0053","doi-asserted-by":"crossref","first-page":"1574","DOI":"10.1089\/ten.tea.2017.0533","article-title":"Biofabricated structures reconstruct functional urinary bladders in radiation-injured rat bladders","volume":"24","author":"Imamura","year":"2018","journal-title":"Tissue Eng Part A"},{"key":"10.1016\/j.trsl.2019.05.001_bib0054","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1007\/s40472-014-0048-z","article-title":"Bioreactor development for lung tissue engineering","volume":"2","author":"Panoskaltsis-Mortari","year":"2015","journal-title":"Curr Transplant Rep"}],"container-title":["Translational Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524419300957?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524419300957?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,15]],"date-time":"2026-05-15T08:14:03Z","timestamp":1778832843000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1931524419300957"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,9]]},"references-count":54,"alternative-id":["S1931524419300957"],"URL":"https:\/\/doi.org\/10.1016\/j.trsl.2019.05.001","relation":{},"ISSN":["1931-5244"],"issn-type":[{"value":"1931-5244","type":"print"}],"subject":[],"published":{"date-parts":[[2019,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"3D bioprinting for lungs and hollow organs","name":"articletitle","label":"Article Title"},{"value":"Translational Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trsl.2019.05.001","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2019 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}