{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,4]],"date-time":"2026-05-04T11:55:51Z","timestamp":1777895751800,"version":"3.51.4"},"reference-count":49,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2021,5,1]],"date-time":"2021-05-01T00:00:00Z","timestamp":1619827200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"}],"funder":[{"DOI":"10.13039\/501100008431","name":"Consejer\u00eda de Educaci\u00f3n, Junta de Castilla y Le\u00f3n","doi-asserted-by":"publisher","award":["SA359U14"],"award-info":[{"award-number":["SA359U14"]}],"id":[{"id":"10.13039\/501100008431","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["IPT-2012-0779-010000"],"award-info":[{"award-number":["IPT-2012-0779-010000"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100014180","name":"Junta de Castilla y Le\u00f3n","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100014180","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100008530","name":"European Regional Development Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008530","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI15\/01055"],"award-info":[{"award-number":["PI15\/01055"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI18\/00996"],"award-info":[{"award-number":["PI18\/00996"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["RD016\/0009\/0025"],"award-info":[{"award-number":["RD016\/0009\/0025"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004587","name":"Instituto de Salud Carlos III","doi-asserted-by":"publisher","award":["PI14\/0177 DT15S\/00166"],"award-info":[{"award-number":["PI14\/0177 DT15S\/00166"]}],"id":[{"id":"10.13039\/501100004587","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000780","name":"European Commission","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000780","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004895","name":"European Social Fund","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004895","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000038","name":"Natural Sciences and Engineering Research Council of Canada","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100000038","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","translationalres.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Translational Research"],"published-print":{"date-parts":[[2021,5]]},"DOI":"10.1016\/j.trsl.2020.11.011","type":"journal-article","created":{"date-parts":[[2020,11,27]],"date-time":"2020-11-27T11:26:31Z","timestamp":1606476391000},"page":"76-91","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["The furosemide stress test and computational modeling identify renal damage sites associated with predisposition to acute kidney injury in rats"],"prefix":"10.1016","volume":"231","author":[{"given":"Alfredo G.","family":"Casanova","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Isabel","family":"Fuentes-Calvo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda T.","family":"Hern\u00e1ndez-S\u00e1nchez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miguel","family":"Quintero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paula","family":"Toral","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda T.","family":"Caballero","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Carlos","family":"Mart\u00ednez-Salgado","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ana I.","family":"Morales","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita T.","family":"Layton","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N\u00e9lida","family":"Eleno","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco J.","family":"L\u00f3pez-Hern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.trsl.2020.11.011_bib0001","first-page":"c179","article-title":"KDIGO clinical practice guidelines for acute kidney injury","volume":"120","author":"Khwaja","year":"2012","journal-title":"Nephron"},{"key":"10.1016\/j.trsl.2020.11.011_bib0002","doi-asserted-by":"crossref","first-page":"R31","DOI":"10.1186\/cc5713","article-title":"Acute Kidney Injury Network: report of an initiative to improve outcomes in acute kidney injury","volume":"11","author":"Mehta","year":"2007","journal-title":"Crit Care"},{"key":"10.1016\/j.trsl.2020.11.011_bib0003","doi-asserted-by":"crossref","first-page":"R204","DOI":"10.1186\/cc2872","volume":"8","author":"Bellomo","year":"2004","journal-title":"Crit Care"},{"key":"10.1016\/j.trsl.2020.11.011_bib0004","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1038\/ki.2013.374","article-title":"Potential use of biomarkers in acute kidney injury: report and summary of recommendations from the 10th Acute Dialysis Quality Initiative consensus conference","volume":"85","author":"Murray","year":"2014","journal-title":"Kidney Int"},{"key":"10.1016\/j.trsl.2020.11.011_bib0005","doi-asserted-by":"crossref","first-page":"313","DOI":"10.1186\/cc11240","article-title":"Subclinical AKI is still AKI","volume":"16","author":"Ronco","year":"2012","journal-title":"Crit Care"},{"key":"10.1016\/j.trsl.2020.11.011_bib0006","doi-asserted-by":"crossref","first-page":"253","DOI":"10.1136\/bmj.1.5691.253","article-title":"Renin and acute renal failure: studies in man","volume":"1","author":"Brown","year":"1970","journal-title":"Br Med J"},{"key":"10.1016\/j.trsl.2020.11.011_bib0007","first-page":"286","article-title":"Acute kidney injury: lessons from experimental models","volume":"169","author":"Heyman","year":"2011"},{"key":"10.1016\/j.trsl.2020.11.011_bib0008","first-page":"526","article-title":"Animal models of acute tubular necrosis","volume":"8","author":"Heyman","year":"2002","journal-title":"Curr Opin Crit Care"},{"key":"10.1016\/j.trsl.2020.11.011_bib0009","doi-asserted-by":"crossref","first-page":"871","DOI":"10.1681\/ASN.2007080913","article-title":"Acute tubular necrosis is a syndrome of physiologic and pathologic dissociation","volume":"19","author":"Rosen","year":"2008","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.trsl.2020.11.011_bib0010","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/S0140-6736(17)30543-3","article-title":"Acute kidney injury: a problem of definition","volume":"389","author":"Barasch","year":"2017","journal-title":"Lancet (London, England)"},{"key":"10.1016\/j.trsl.2020.11.011_bib0011","first-page":"1","article-title":"A comment on the diagnosis and definition of acute kidney injury","author":"Selby","year":"2019","journal-title":"Nephron"},{"key":"10.1016\/j.trsl.2020.11.011_bib0012","doi-asserted-by":"crossref","first-page":"R207","DOI":"10.1186\/cc13015","article-title":"Development and standardization of a furosemide stress test to predict the severity of acute kidney injury","volume":"17","author":"Chawla","year":"2013","journal-title":"Crit Care"},{"key":"10.1016\/j.trsl.2020.11.011_bib0013","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1016\/j.jcrc.2019.04.011","article-title":"The furosemide stress test for prediction of worsening acute kidney injury in critically ill patients: A multicenter, prospective, observational study","volume":"52","author":"Rewa","year":"2019","journal-title":"J Crit Care"},{"key":"10.1016\/j.trsl.2020.11.011_bib0014","doi-asserted-by":"crossref","first-page":"1021","DOI":"10.1124\/jpet.103.059139","article-title":"Interactions of human organic anion transporters with diuretics","volume":"308","author":"Hasannejad","year":"2004","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.trsl.2020.11.011_bib0015","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1681\/ASN.2005090966","article-title":"Multidrug resistance-associated protein 4 is involved in the urinary excretion of hydrochlorothiazide and furosemide","volume":"18","author":"Hasegawa","year":"2007","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.trsl.2020.11.011_bib0016","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1016\/j.bbrc.2014.08.068","article-title":"Molecular mechanism of an adverse drug-drug interaction of allopurinol and furosemide in gout treatment","volume":"452","author":"Knake","year":"2014","journal-title":"Biochem Biophys Res Commun"},{"key":"10.1016\/j.trsl.2020.11.011_bib0017","doi-asserted-by":"crossref","first-page":"1248","DOI":"10.2215\/CJN.09630818","article-title":"Clinical pharmacology in diuretic use","volume":"14","author":"Ellison","year":"2019","journal-title":"Clin J Am Soc Nephrol"},{"key":"10.1016\/j.trsl.2020.11.011_bib0018","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1016\/S0022-3565(24)38896-2","article-title":"Interaction and transport of thiazide diuretics, loop diuretics, and acetazolamide via rat renal organic anion transporter rOAT1","volume":"295","author":"Uwai","year":"2000","journal-title":"J Pharmacol Exp Ther"},{"key":"10.1016\/j.trsl.2020.11.011_bib0019","doi-asserted-by":"crossref","first-page":"119","DOI":"10.1152\/ajplegacy.1973.225.1.119","article-title":"Furosemide effect on isolated perfused tubules","volume":"225","author":"Burg","year":"1973","journal-title":"Am J Physiol Content"},{"key":"10.1016\/j.trsl.2020.11.011_bib0020","doi-asserted-by":"crossref","first-page":"435","DOI":"10.1002\/cpt1979254435","article-title":"Azosemide, a \u201cloop\u201d diuretic, and furosemide","volume":"25","author":"Brater","year":"1979","journal-title":"Clin Pharmacol Ther"},{"key":"10.1016\/j.trsl.2020.11.011_bib0021","doi-asserted-by":"crossref","first-page":"2023","DOI":"10.1681\/ASN.2014060535","article-title":"Furosemide stress test and biomarkers for the prediction of AKI severity","volume":"26","author":"Koyner","year":"2015","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.trsl.2020.11.011_bib0022","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1186\/s13054-018-2021-1","article-title":"Early versus standard initiation of renal replacement therapy in furosemide stress test non-responsive acute kidney injury patients (the FST trial)","volume":"22","author":"Lumlertgul","year":"2018","journal-title":"Crit Care"},{"key":"10.1016\/j.trsl.2020.11.011_bib0023","first-page":"1","article-title":"Furosemide stress test as a predicting biomarker for delayed graft function in kidney transplantation","author":"Udomkarnjananun","year":"2019","journal-title":"Nephron"},{"key":"10.1016\/j.trsl.2020.11.011_bib0024","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s13613-018-0355-0","article-title":"Response to different furosemide doses predicts AKI progression in ICU patients with elevated plasma NGAL levels","volume":"8","author":"Matsuura","year":"2018","journal-title":"Ann Intens Care"},{"key":"10.1016\/j.trsl.2020.11.011_bib0025","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1080\/1354750X.2017.1387934","article-title":"The prognostic value of the furosemide stress test in predicting delayed graft function following deceased donor kidney transplantation","volume":"23","author":"McMahon","year":"2018","journal-title":"Biomarkers"},{"key":"10.1016\/j.trsl.2020.11.011_bib0026","doi-asserted-by":"crossref","first-page":"1006","DOI":"10.1038\/ki.2010.267","article-title":"Sub-nephrotoxic doses of gentamicin predispose animals to developing acute kidney injury and to excrete ganglioside M2 activator protein","volume":"78","author":"Quiros","year":"2010","journal-title":"Kidney Int"},{"key":"10.1016\/j.trsl.2020.11.011_bib0027","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.tox.2012.12.006","article-title":"Increased urinary excretion of albumin, hemopexin, transferrin and VDBP correlates with chronic sensitization to gentamicin nephrotoxicity in rats","volume":"304","author":"Vicente-Vicente","year":"2013","journal-title":"Toxicology"},{"key":"10.1016\/j.trsl.2020.11.011_bib0028","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1016\/j.toxlet.2014.11.033","article-title":"Sub-nephrotoxic cisplatin sensitizes rats to acute renal failure and increases urinary excretion of fumarylacetoacetase","volume":"234","author":"Vicente-Vicente","year":"2015","journal-title":"Toxicol Lett"},{"key":"10.1016\/j.trsl.2020.11.011_bib0029","doi-asserted-by":"crossref","DOI":"10.1016\/j.biopha.2019.109684","article-title":"Urinary transferrin pre-emptively identifies the risk of renal damage posed by subclinical tubular alterations","volume":"121","author":"Casanova","year":"2020","journal-title":"Biomed Pharmacother"},{"key":"10.1016\/j.trsl.2020.11.011_bib0030","doi-asserted-by":"crossref","first-page":"248","DOI":"10.1016\/0003-2697(76)90527-3","article-title":"A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding","volume":"72","author":"Bradford","year":"1976","journal-title":"Anal Biochem"},{"key":"10.1016\/j.trsl.2020.11.011_bib0031","doi-asserted-by":"crossref","first-page":"F1378","DOI":"10.1152\/ajprenal.00293.2016","article-title":"A computational model for simulating solute transport and oxygen consumption along the nephrons","volume":"311","author":"Layton","year":"2016","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.trsl.2020.11.011_bib0032","doi-asserted-by":"crossref","first-page":"F1217","DOI":"10.1152\/ajprenal.00294.2016","article-title":"Solute transport and oxygen consumption along the nephrons: effects of na+ transport inhibitors","volume":"311","author":"Layton","year":"2016","journal-title":"Am J Physiol - Ren Physiol"},{"key":"10.1016\/j.trsl.2020.11.011_bib0033","doi-asserted-by":"crossref","first-page":"518","DOI":"10.1038\/ki.2010.439","article-title":"Urinary levels of regenerating islet-derived protein III \u03b2 and gelsolin differentiate gentamicin from cisplatin-induced acute kidney injury in rats","volume":"79","author":"Ferreira","year":"2011","journal-title":"Kidney Int"},{"key":"10.1016\/j.trsl.2020.11.011_bib0034","doi-asserted-by":"crossref","first-page":"33","DOI":"10.1038\/ki.2010.337","article-title":"New insights into the mechanism of aminoglycoside nephrotoxicity: an integrative point of view","volume":"79","author":"Lopez-Novoa","year":"2011","journal-title":"Kidney Int"},{"key":"10.1016\/j.trsl.2020.11.011_bib0035","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/j.taap.2018.04.010","article-title":"N-acetylcysteine transforms necrosis into apoptosis and affords tailored protection from cisplatin cytotoxicity","volume":"349","author":"Sancho-Mart\u00ednez","year":"2018","journal-title":"Toxicol Appl Pharmacol"},{"key":"10.1016\/j.trsl.2020.11.011_bib0036","doi-asserted-by":"crossref","first-page":"803","DOI":"10.3109\/10408444.2011.602662","article-title":"An integrative view of the pathophysiological events leading to cisplatin nephrotoxicity","volume":"41","author":"S\u00e1nchez-Gonz\u00e1lez","year":"2011","journal-title":"Crit Rev Toxicol"},{"issue":"Pt A","key":"10.1016\/j.trsl.2020.11.011_bib0037","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1016\/j.fct.2017.06.047","article-title":"Differential effect of quercetin on cisplatin-induced toxicity in kidney and tumor tissues","volume":"107","author":"S\u00e1nchez-Gonz\u00e1lez","year":"2017","journal-title":"Food Chem Toxicol"},{"key":"10.1016\/j.trsl.2020.11.011_bib0038","doi-asserted-by":"crossref","first-page":"3484","DOI":"10.1093\/ndt\/gfr195","article-title":"Quercetin reduces cisplatin nephrotoxicity in rats without compromising its anti-tumour activity","volume":"26","author":"Sanchez-Gonzalez","year":"2011","journal-title":"Nephrol Dial Transplant"},{"key":"10.1016\/j.trsl.2020.11.011_bib0039","doi-asserted-by":"crossref","first-page":"e404","DOI":"10.1097\/TP.0000000000002313","article-title":"Cardiotrophin-1 improves kidney preservation, graft function, and survival in transplanted rats","volume":"102","author":"Garc\u00eda-Cenador","year":"2018","journal-title":"Transplantation"},{"key":"10.1016\/j.trsl.2020.11.011_bib0040","doi-asserted-by":"crossref","first-page":"1034","DOI":"10.1097\/TP.0b013e3182a74db4","article-title":"Cardiotrophin-1 administration protects from ischemia-reperfusion renal injury and inflammation","volume":"96","author":"Garcia-Cenador","year":"2013","journal-title":"Transplant J"},{"key":"10.1016\/j.trsl.2020.11.011_bib0041","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1111\/j.1440-1681.1994.tb02472.x","article-title":"Lysosomal iron accumulation and tubular damage in rat puromycin nephrosis and ageing","volume":"21","author":"Harris","year":"1994","journal-title":"Clin Exp Pharmacol Physiol"},{"key":"10.1016\/j.trsl.2020.11.011_bib0042","doi-asserted-by":"crossref","first-page":"701","DOI":"10.1080\/14756366.2018.1445735","article-title":"Identification of cisplatin-binding sites on the large cytoplasmic loop of the Na+\/K+-ATPase","volume":"33","author":"\u0160eflov\u00e1","year":"2018","journal-title":"J Enzyme Inhib Med Chem"},{"key":"10.1016\/j.trsl.2020.11.011_bib0043","doi-asserted-by":"crossref","first-page":"194","DOI":"10.5507\/bp.2014.018","article-title":"Na+\/K+-ATPase inhibition by cisplatin and consequences for cisplatin nephrotoxicity","volume":"158","author":"Kubala","year":"2014","journal-title":"Biomed Pap"},{"key":"10.1016\/j.trsl.2020.11.011_bib0044","doi-asserted-by":"crossref","first-page":"1633","DOI":"10.1038\/sj.bjc.6601344","article-title":"Severe intracellular magnesium and potassium depletion in patients after treatment with cisplatin","volume":"89","author":"Lajer","year":"2003","journal-title":"Br J Cancer"},{"key":"10.1016\/j.trsl.2020.11.011_bib0045","doi-asserted-by":"crossref","first-page":"49","DOI":"10.1111\/apha.12707","article-title":"Na(+) dependence of K(+) -induced natriuresis, kaliuresis and Na(+) \/Cl(-) cotransporter dephosphorylation","volume":"218","author":"Jensen","year":"2016","journal-title":"Acta Physiol (Oxf)"},{"key":"10.1016\/j.trsl.2020.11.011_bib0046","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1681\/ASN.2016020229","article-title":"Proximal tubule CD73 Is Critical in renal ischemia-reperfusion injury protection","volume":"28","author":"Sung","year":"2017","journal-title":"J Am Soc Nephrol"},{"key":"10.1016\/j.trsl.2020.11.011_bib0047","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1016\/j.pharmthera.2012.07.003","article-title":"Subcellular targets of cisplatin cytotoxicity: An integrated view","volume":"136","author":"Sancho-Mart\u00ednez","year":"2012","journal-title":"Pharmacol Ther"},{"key":"10.1016\/j.trsl.2020.11.011_bib0048","doi-asserted-by":"crossref","first-page":"1048","DOI":"10.1038\/ki.1995.151","article-title":"Modulation of sodium-coupled uptake and membrane fluidity by cisplatin in renal proximal tubular cells in primary culture and brush-border membrane vesicles","volume":"47","author":"Courjault-Gautier","year":"1995","journal-title":"Kidney Int"},{"key":"10.1016\/j.trsl.2020.11.011_bib0049","doi-asserted-by":"crossref","first-page":"2656","DOI":"10.2174\/092986708786242903","article-title":"Cisplatin cytotoxicity: DNA and plasma membrane targets","volume":"15","author":"Rebillard","year":"2008","journal-title":"Curr Med Chem"}],"container-title":["Translational Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524420302929?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524420302929?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T08:04:29Z","timestamp":1777622669000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1931524420302929"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,5]]},"references-count":49,"alternative-id":["S1931524420302929"],"URL":"https:\/\/doi.org\/10.1016\/j.trsl.2020.11.011","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.739150007.793580888","asserted-by":"object"}]},"ISSN":["1931-5244"],"issn-type":[{"value":"1931-5244","type":"print"}],"subject":[],"published":{"date-parts":[[2021,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"The furosemide stress test and computational modeling identify renal damage sites associated with predisposition to acute kidney injury in rats","name":"articletitle","label":"Article Title"},{"value":"Translational Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trsl.2020.11.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Crown Copyright \u00a9 2020 Published by Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}