{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,28]],"date-time":"2026-09-28T17:18:42Z","timestamp":1790615922288,"version":"4.1.0"},"reference-count":58,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2022,8,1]],"date-time":"2022-08-01T00:00:00Z","timestamp":1659312000000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100004006","name":"Istanbul University Scientific Research Projects Unit","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004006","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004410","name":"Scientific and Technological Research Council of Turkey","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004410","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","translationalres.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Translational Research"],"published-print":{"date-parts":[[2022,8]]},"DOI":"10.1016\/j.trsl.2022.03.012","type":"journal-article","created":{"date-parts":[[2022,4,3]],"date-time":"2022-04-03T01:21:10Z","timestamp":1648948870000},"page":"87-101","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"C","title":["Exendin-4 inhibits small intestinal glucose sensing and absorption through repression of T1R2\/T1R3 sweet taste receptor signalling in streptozotocin diabetic mice"],"prefix":"10.1016","volume":"246","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7755-0762","authenticated-orcid":false,"given":"MERVE","family":"ERCIN","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SELDA","family":"GEZGINCI-OKTAYOGLU","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"SEHNAZ","family":"BOLKENT","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.trsl.2022.03.012_bib0001","unstructured":"Accessed from: https:\/\/www.diabetesatlas.org\/en\/, Accessed 2019"},{"key":"10.1016\/j.trsl.2022.03.012_bib0002","unstructured":"Prevention of diabetes mellitus. Report of a WHO Study Group. 1994. World health organization technical report series, 844, 1\u2013100."},{"key":"10.1016\/j.trsl.2022.03.012_bib0003","series-title":"Gastrointestinal function in diabetes mellitus","author":"Horowitz","year":"2004"},{"key":"10.1016\/j.trsl.2022.03.012_bib0004","first-page":"1697","article-title":"Gastrointestinal complications of diabetes","volume":"77","author":"Shakil","year":"2008","journal-title":"Am Fam Physician"},{"key":"10.1016\/j.trsl.2022.03.012_bib0005","doi-asserted-by":"crossref","first-page":"884","DOI":"10.2337\/dc16-0351","article-title":"Roles of the gut in glucose homeostasis","volume":"39","author":"Holst","year":"2016","journal-title":"Diabetes care"},{"key":"10.1016\/j.trsl.2022.03.012_bib0006","doi-asserted-by":"crossref","first-page":"R95","DOI":"10.1530\/JOE-16-0056","article-title":"Targeting the gastrointestinal tract to treat type 2 diabetes","volume":"230","author":"Bauer","year":"2016","journal-title":"J. Endocrinol."},{"key":"10.1016\/j.trsl.2022.03.012_bib0007","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1124\/pr.108.000604","article-title":"The role of incretins in glucose homeostasis and diabetes treatment","volume":"60","author":"Kim","year":"2008","journal-title":"Pharmacol. Rev"},{"key":"10.1016\/j.trsl.2022.03.012_bib0008","doi-asserted-by":"crossref","first-page":"525","DOI":"10.1016\/S2213-8587(15)00482-9","article-title":"The incretin effect in healthy individuals and those with type 2 diabetes: physiology, pathophysiology, and response to therapeutic interventions\u201d","volume":"4","author":"Nauck","year":"2016","journal-title":"Lancet Diabetes Endocrinol"},{"key":"10.1016\/j.trsl.2022.03.012_bib0009","doi-asserted-by":"crossref","first-page":"S73","DOI":"10.1016\/S1262-3636(08)73398-6","article-title":"GLP-1 receptor signaling: effects on pancreatic beta-cell proliferation and survival","volume":"34","author":"Buteau","year":"2008","journal-title":"Diabetes Metab"},{"key":"10.1016\/j.trsl.2022.03.012_bib0010","doi-asserted-by":"crossref","first-page":"E538","DOI":"10.1152\/ajpendo.00070.2007","article-title":"Ubiquitination is involved in glucose-mediated downregulation of GIP receptors in islets","volume":"293","author":"Zhou","year":"2007","journal-title":"Am. J. Physiol. - Endocrinol. Metab"},{"key":"10.1016\/j.trsl.2022.03.012_bib0011","doi-asserted-by":"crossref","first-page":"664","DOI":"10.1111\/j.1365-2982.2010.01476.x","article-title":"Peripheral motor action of glucagon-like peptide-1 through enteric neuronal receptors","volume":"22","author":"Amato","year":"2010","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.trsl.2022.03.012_bib0012","doi-asserted-by":"crossref","first-page":"301","DOI":"10.1586\/17474124.2014.887439","article-title":"Glucose absorption in small intestinal diseases","volume":"8","author":"Thazhath","year":"2014","journal-title":"Expert Rev Gastroenterol Hepatol"},{"key":"10.1016\/j.trsl.2022.03.012_bib0013","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1111\/j.1463-1326.2011.01452.x","article-title":"Regulation of glucagon secretion by incretins","volume":"13","author":"Holst","year":"2011","journal-title":"Diabetes Obes Metab"},{"key":"10.1016\/j.trsl.2022.03.012_bib0014","doi-asserted-by":"crossref","first-page":"75","DOI":"10.1016\/j.peptides.2013.01.014","article-title":"Glucagon-like peptides 1 and 2 in health and disease: a review","volume":"44","author":"Marathe","year":"2013","journal-title":"Peptides"},{"key":"10.1016\/j.trsl.2022.03.012_bib0015","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1016\/j.beem.2007.07.005","article-title":"DPP-4 inhibitors","volume":"21","author":"Ahr\u00e9n","year":"2007","journal-title":"Best Pract Res Clin Endocrinol Metab"},{"key":"10.1016\/j.trsl.2022.03.012_bib0016","doi-asserted-by":"crossref","first-page":"3082","DOI":"10.1210\/jc.2002-021545","article-title":"Synthetic exendin-4 (exenatide) significantly reduces postprandial and fasting plasma glucose in subjects with type 2 diabetes","volume":"88","author":"Kolterman","year":"2003","journal-title":"J Clin Endocrinol Metab"},{"key":"10.1016\/j.trsl.2022.03.012_bib0017","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.regpep.2003.10.028","article-title":"Pharmacology of exenatide (synthetic exendin-4): a potential therapeutic for improved glycemic control of type 2 diabetes","volume":"117","author":"Nielsen","year":"2004","journal-title":"Regul. Pept."},{"key":"10.1016\/j.trsl.2022.03.012_bib0018","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1111\/j.1749-6632.2009.04485.x","article-title":"T1r3 and alpha-gustducin in gut regulate secretion of glucagon-like peptide-1","volume":"1170","author":"Kokrashvili","year":"2009","journal-title":"Ann. N. Y. Acad. Sci"},{"key":"10.1016\/j.trsl.2022.03.012_bib0019","doi-asserted-by":"crossref","first-page":"337","DOI":"10.1136\/gut.2008.148932","article-title":"Expression of taste molecules in the upper gastrointestinal tract in humans with and without type 2 diabetes","volume":"58","author":"Young","year":"2009","journal-title":"Gut"},{"key":"10.1016\/j.trsl.2022.03.012_bib0020","doi-asserted-by":"crossref","first-page":"3336","DOI":"10.2337\/db13-1018","article-title":"How sweet it is: intestinal sweet taste receptors in type 2 diabetes","volume":"62","author":"Greenfield","year":"2013","journal-title":"Diabetes"},{"issue":"Pt 1(Pt 1)","key":"10.1016\/j.trsl.2022.03.012_bib0021","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1042\/bj3500155","article-title":"The diffusive component of intestinal glucose absorption is mediated by the glucose-induced recruitment of GLUT2 to the brush-border membrane","volume":"350","author":"Kellett","year":"2000","journal-title":"Biochem. J."},{"key":"10.1016\/j.trsl.2022.03.012_bib0022","doi-asserted-by":"crossref","first-page":"630","DOI":"10.1093\/jn\/132.4.630","article-title":"Quercetin-3-glucoside is transported by the glucose carrier SGLT1 across the brush border membrane of rat small intestine","volume":"132","author":"Wolffram","year":"2002","journal-title":"J Nutr"},{"key":"10.1016\/j.trsl.2022.03.012_bib0023","doi-asserted-by":"crossref","first-page":"713","DOI":"10.1111\/j.1432-1033.1994.tb18550.x","article-title":"Facilitative glucose transporters","volume":"219","author":"Mueckler","year":"1994","journal-title":"Eur J Biochem"},{"key":"10.1016\/j.trsl.2022.03.012_bib0024","first-page":"379","article-title":"Functional roles of the sweet taste receptor in oral and extraoral tissues","volume":"17","author":"Laffitte","year":"2014","journal-title":"Curr. Opin. Clin. Nutr. Metab. Care"},{"key":"10.1016\/j.trsl.2022.03.012_bib0025","doi-asserted-by":"crossref","first-page":"e12808","DOI":"10.1111\/jfbc.12808","article-title":"The effects of vitamins and selenium mixture or ranitidine against small intestinal injury induced by indomethacin in adult rats","volume":"43","author":"Turkyilmaz","year":"2019","journal-title":"J. Food Biochem."},{"key":"10.1016\/j.trsl.2022.03.012_bib0026","doi-asserted-by":"crossref","first-page":"181","DOI":"10.1254\/jjp.87.181","article-title":"Adenylate cyclase\/protein kinase A signaling pathway enhances angiogenesis through induction of vascular endothelial growth factor in vivo","volume":"87","author":"Amano","year":"2001","journal-title":"Japanese J. Pharmacol"},{"key":"10.1016\/j.trsl.2022.03.012_bib0027","first-page":"3744","article-title":"The association between the expression of PAR2 and TMEM16A and neuropathic pain","volume":"17","author":"Zhang","year":"2018","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.trsl.2022.03.012_bib0028","doi-asserted-by":"crossref","first-page":"641","DOI":"10.1139\/O09-046","article-title":"Exendin-4 exerts its effects through the NGF\/p75NTR system in diabetic mouse pancreas","volume":"87","author":"Gezginci-Oktayoglu","year":"2009","journal-title":"Biochem Cell Biol"},{"key":"10.1016\/j.trsl.2022.03.012_bib0029","doi-asserted-by":"crossref","first-page":"1111","DOI":"10.1172\/JCI25102","article-title":"Inflammation, stress, and diabetes","volume":"115","author":"Wellen","year":"2005","journal-title":"J. Clin. Invest"},{"key":"10.1016\/j.trsl.2022.03.012_bib0030","doi-asserted-by":"crossref","first-page":"725","DOI":"10.3389\/fnins.2018.00725","article-title":"Inflammation and gut-brain axis during type 2 diabetes: focus on the crosstalk between intestinal immune cells and enteric nervous system","volume":"12","author":"Bessac","year":"2018","journal-title":"Front. Neurosci"},{"key":"10.1016\/j.trsl.2022.03.012_bib0031","doi-asserted-by":"crossref","first-page":"1376","DOI":"10.1126\/science.aar3318","article-title":"Hyperglycemia drives intestinal barrier dysfunction and risk for enteric infection","volume":"359","author":"Thaiss","year":"2018","journal-title":"Science (New York, N.Y.)"},{"key":"10.1016\/j.trsl.2022.03.012_bib0032","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.1021\/pr060665l","article-title":"Tumor Necrosis Factor-alpha- and interleukin-1-induced cellular responses: coupling proteomic and genomic information","volume":"6","author":"Ott","year":"2007","journal-title":"J. Proteome Res."},{"key":"10.1016\/j.trsl.2022.03.012_bib0033","first-page":"31","article-title":"Type 2 diabetes mechanisms, role of cytokines and their variations in disease development","volume":"43","author":"Ates","year":"2018","journal-title":"FABAD J. Pharm. Sci."},{"key":"10.1016\/j.trsl.2022.03.012_bib0034","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1038\/360361a0","article-title":"Natural inhibitor of transforming growth factor-beta protects against scarring in experimental kidney disease","volume":"360","author":"Border","year":"1992","journal-title":"Nature"},{"key":"10.1016\/j.trsl.2022.03.012_bib0035","doi-asserted-by":"crossref","first-page":"1486","DOI":"10.1172\/JCI200319270","article-title":"Targeted disruption of TGF\u03b21\/Smad3 signalling protects against renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction","volume":"112","author":"Sato","year":"2003","journal-title":"J Clin Invest"},{"key":"10.1016\/j.trsl.2022.03.012_bib0036","doi-asserted-by":"crossref","first-page":"G684","DOI":"10.1152\/ajpgi.00474.2010","article-title":"Intestinal myofibroblasts: targets for stem cell therapy","volume":"300","author":"Mifflin","year":"2011","journal-title":"Am. J. Physiol. Gastrointest. Liver Physiol"},{"key":"10.1016\/j.trsl.2022.03.012_bib0037","doi-asserted-by":"crossref","first-page":"3635","DOI":"10.3748\/wjg.v18.i28.3635","article-title":"Cellular and molecular mechanisms of intestinal fibrosis","volume":"18","author":"Speca","year":"2012","journal-title":"World J. Gastroenterol"},{"key":"10.1016\/j.trsl.2022.03.012_bib0038","doi-asserted-by":"crossref","first-page":"873","DOI":"10.1016\/j.cellsig.2004.02.007","article-title":"TGF-beta and TNF-alpha: antagonistic cytokines controlling type I collagen gene expression","volume":"16","author":"Verrecchia","year":"2004","journal-title":"Cell. Signal."},{"key":"10.1016\/j.trsl.2022.03.012_bib0039","doi-asserted-by":"crossref","first-page":"G28","DOI":"10.1152\/ajpgi.00437.2005","article-title":"Identification of apoptotic genes mediating TGF-beta\/Smad3-induced cell death in intestinal epithelial cells using a genomic approach","volume":"292","author":"Cao","year":"2007","journal-title":"Am. J. Physiol. - Gastrointest. Liver Physiol."},{"key":"10.1016\/j.trsl.2022.03.012_bib0040","doi-asserted-by":"crossref","first-page":"993","DOI":"10.1152\/physrev.1994.74.4.993","article-title":"Molecular physiology of sodium-glucose cotransporters","volume":"74","author":"Hediger","year":"1994","journal-title":"Physiological reviews"},{"issue":"4 Pt 1","key":"10.1016\/j.trsl.2022.03.012_bib0041","first-page":"G541","article-title":"Glucose transporters in the regulation of intestinal, renal, and liver glucose fluxes","volume":"270","author":"Thorens","year":"1996","journal-title":"Am. J. Physiol."},{"key":"10.1016\/j.trsl.2022.03.012_bib0042","doi-asserted-by":"crossref","first-page":"312","DOI":"10.1007\/s11605-011-1752-y","article-title":"Acute enterocyte adaptation to luminal glucose: a posttranslational mechanism for rapid apical recruitment of the transporter GLUT2","volume":"16","author":"Chaudhry","year":"2012","journal-title":"J Gastrointest Surg"},{"key":"10.1016\/j.trsl.2022.03.012_bib0043","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1111\/jdi.12065","article-title":"Glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1: Incretin actions beyond the pancreas","volume":"4","author":"Seino","year":"2013","journal-title":"J. Diabetes Investig."},{"key":"10.1016\/j.trsl.2022.03.012_bib0044","doi-asserted-by":"crossref","first-page":"E1358","DOI":"10.1152\/ajpendo.00412.2009","article-title":"Activation of sodium-glucose cotransporter 1 ameliorates hyperglycemia by mediating incretin secretion in mice","volume":"297","author":"Moriya","year":"2009","journal-title":"Am. J. Physiol. - Endocrinol. Metab"},{"key":"10.1016\/j.trsl.2022.03.012_bib0045","doi-asserted-by":"crossref","first-page":"191","DOI":"10.1530\/JOE-14-0161","article-title":"KATP channel as well as SGLT1 participates in GIP secretion in the diabetic state","volume":"222","author":"Ogata","year":"2014","journal-title":"The J. Endocrinol."},{"key":"10.1016\/j.trsl.2022.03.012_bib0046","doi-asserted-by":"crossref","first-page":"187","DOI":"10.2337\/db11-1029","article-title":"Na(+)-D-glucose cotransporter SGLT1 is pivotal for intestinal glucose absorption and glucose-dependent incretin secretion","volume":"61","author":"Gorboulev","year":"2012","journal-title":"Diabetes"},{"key":"10.1016\/j.trsl.2022.03.012_bib0047","doi-asserted-by":"crossref","first-page":"250","DOI":"10.1124\/jpet.113.203364","article-title":"LX4211 increases serum glucagon-like peptide 1 and peptide YY levels by reducing sodium\/glucose cotransporter 1 (SGLT1)-mediated absorption of intestinal glucose","volume":"345","author":"Powell","year":"2013","journal-title":"J. Pharmacol. Exp. Ther"},{"key":"10.1016\/j.trsl.2022.03.012_bib0048","doi-asserted-by":"crossref","first-page":"G241","DOI":"10.1152\/ajpgi.00310.2001","article-title":"Expression of monosaccharide transporters in intestine of diabetic humans","volume":"282","author":"Dyer","year":"2002","journal-title":"Am J Physiol Gastrointest Liver Physiol"},{"issue":"Pt1","key":"10.1016\/j.trsl.2022.03.012_bib0049","doi-asserted-by":"crossref","first-page":"379","DOI":"10.1113\/jphysiol.2007.130906","article-title":"Sweet taste receptors in rat small intestine stimulate glucose absorption through apical GLUT2","volume":"582","author":"Mace","year":"2007","journal-title":"J Physiol"},{"key":"10.1016\/j.trsl.2022.03.012_bib0050","doi-asserted-by":"crossref","first-page":"15075","DOI":"10.1073\/pnas.0706678104","article-title":"T1R3 and gustducin in gut sense sugars to regulate expression of Na\u00a0+\u00a0-glucose cotransporter 1","volume":"104","author":"Margolskee","year":"2007","journal-title":"Proc Natl Acad Sci USA,;"},{"key":"10.1016\/j.trsl.2022.03.012_bib0051","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1038\/nrgastro.2013.180","article-title":"The gut as a sensory organ","volume":"10","author":"Furness","year":"2013","journal-title":"Nat. Rev. Gastroenterol. Hepatol."},{"key":"10.1016\/j.trsl.2022.03.012_bib0052","doi-asserted-by":"crossref","unstructured":"Kochem, M. 2017. \u201cType 1 taste receptors in taste and metabolism. Ann. Nutr. Metab\u201d, 70 Suppl 3, 27\u201336.","DOI":"10.1159\/000478760"},{"key":"10.1016\/j.trsl.2022.03.012_bib0053","doi-asserted-by":"crossref","first-page":"15160","DOI":"10.1073\/pnas.2334159100","article-title":"Intracellular Ca2+ and the phospholipid PIP2 regulate the taste transduction ion channel TRPM5","volume":"100","author":"Liu","year":"2003","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.trsl.2022.03.012_bib0054","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1093\/chemse\/bjj062","article-title":"Taste responses to sweet stimuli in alpha-gustducin knockout and wild-type mice","volume":"31","author":"Danilova","year":"2006","journal-title":"Chemical Senses"},{"key":"10.1016\/j.trsl.2022.03.012_bib0055","doi-asserted-by":"crossref","first-page":"3532","DOI":"10.2337\/db13-0581","article-title":"Disordered control of intestinal sweet taste receptor expression and glucose absorption in type 2 diabetes","volume":"62","author":"Young","year":"2013","journal-title":"Diabetes"},{"key":"10.1016\/j.trsl.2022.03.012_bib0056","doi-asserted-by":"crossref","first-page":"5830","DOI":"10.1021\/bi062309m","article-title":"Differential structural properties of GLP-1 and exendin-4 determine their relative affinity for the GLP-1 receptor N-terminal extracellular domain","volume":"46","author":"Runge","year":"2007","journal-title":"Biochemistry"},{"key":"10.1016\/j.trsl.2022.03.012_bib0057","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1186\/1475-2840-10-6","article-title":"Glucagon-like peptide-1 enhances cardiac L-type Ca2+ currents via activation of the cAMP-dependent protein kinase A pathway","volume":"10","author":"Xiao","year":"2011","journal-title":"Cardiovascular diabetology"},{"key":"10.1016\/j.trsl.2022.03.012_bib0058","first-page":"1934","article-title":"Glucagon\u2011like peptide\u20111 analogue exendin\u20114 modulates serotonin transporter expression in intestinal epithelial cells","volume":"21","author":"Cui","year":"2020","journal-title":"Mol Med Rep"}],"container-title":["Translational Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524422000688?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524422000688?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T12:45:57Z","timestamp":1761828357000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1931524422000688"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,8]]},"references-count":58,"alternative-id":["S1931524422000688"],"URL":"https:\/\/doi.org\/10.1016\/j.trsl.2022.03.012","relation":{},"ISSN":["1931-5244"],"issn-type":[{"value":"1931-5244","type":"print"}],"subject":[],"published":{"date-parts":[[2022,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Exendin-4 inhibits small intestinal glucose sensing and absorption through repression of T1R2\/T1R3 sweet taste receptor signalling in streptozotocin diabetic mice","name":"articletitle","label":"Article Title"},{"value":"Translational Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trsl.2022.03.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2022 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}