{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,16]],"date-time":"2026-09-16T16:25:34Z","timestamp":1789575934785,"version":"build-2803163510"},"reference-count":55,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,12,1]],"date-time":"2023-12-01T00:00:00Z","timestamp":1701388800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2016YFD0501205"],"award-info":[{"award-number":["2016YFD0501205"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","translationalres.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Translational Research"],"published-print":{"date-parts":[[2023,12]]},"DOI":"10.1016\/j.trsl.2023.07.003","type":"journal-article","created":{"date-parts":[[2023,7,6]],"date-time":"2023-07-06T21:14:10Z","timestamp":1688678050000},"page":"1-11","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["N-acetylcysteine combined with insulin attenuates myocardial injury in canines with type 1 diabetes mellitus by modulating TNF-\u03b1-mediated apoptotic pathways and affecting linear ubiquitination"],"prefix":"10.1016","volume":"262","author":[{"given":"Jianjia","family":"Huang","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoyue","family":"Pang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinting","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenyue","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuluan","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongmei","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenting","family":"Xie","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yuman","family":"Bai","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuilian","family":"Zhou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jianzhao","family":"Liao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaojun","family":"Xiong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhaoxin","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rongsheng","family":"Su","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"S 01","key":"10.1016\/j.trsl.2023.07.003_bib0001","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1055\/a-1018-9078","article-title":"Definition, classification and diagnosis of diabetes mellitus","volume":"127","author":"Petersmann","year":"2019","journal-title":"Exp Clin Endocrinol Diabetes"},{"key":"10.1016\/j.trsl.2023.07.003_bib0002","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1007\/978-1-4614-5441-0_2","article-title":"Classification of diabetes","volume":"771","author":"Maraschin","year":"2012","journal-title":"Adv Exp Med Biol"},{"issue":"3","key":"10.1016\/j.trsl.2023.07.003_bib0003","doi-asserted-by":"crossref","first-page":"375","DOI":"10.1016\/j.pharmthera.2014.01.003","article-title":"Diabetic cardiomyopathy: mechanisms and new treatment strategies targeting antioxidant signaling pathways","volume":"142","author":"Huynh","year":"2014","journal-title":"Pharmacol Ther"},{"issue":"11","key":"10.1016\/j.trsl.2023.07.003_bib0004","doi-asserted-by":"crossref","first-page":"1736","DOI":"10.1161\/CIRCRESAHA.116.306842","article-title":"Lipid use and misuse by the heart","volume":"118","author":"Schulze","year":"2016","journal-title":"Circ Res"},{"issue":"12","key":"10.1016\/j.trsl.2023.07.003_bib0005","doi-asserted-by":"crossref","first-page":"887","DOI":"10.1016\/j.cardfail.2017.08.456","article-title":"Chronic neuregulin-1beta treatment mitigates the progression of postmyocardial infarction heart failure in the setting of type 1 diabetes mellitus by suppressing myocardial apoptosis, fibrosis, and key oxidant-producing enzymes","volume":"23","author":"Gupte","year":"2017","journal-title":"J Card Fail"},{"issue":"4","key":"10.1016\/j.trsl.2023.07.003_bib0006","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1007\/s00125-014-3171-6","article-title":"Molecular mechanisms of diabetic cardiomyopathy","volume":"57","author":"Bugger","year":"2014","journal-title":"Diabetologia"},{"issue":"6","key":"10.1016\/j.trsl.2023.07.003_bib0007","doi-asserted-by":"crossref","first-page":"H1237","DOI":"10.1152\/ajpheart.00004.2019","article-title":"Hydrogen sulfide-mediated regulation of cell death signaling ameliorates adverse cardiac remodeling and diabetic cardiomyopathy","volume":"316","author":"Kar","year":"2019","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"1","key":"10.1016\/j.trsl.2023.07.003_bib0008","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.jchf.2012.10.002","article-title":"Heart failure","volume":"1","author":"Braunwald","year":"2013","journal-title":"JACC Heart Fail"},{"issue":"10","key":"10.1016\/j.trsl.2023.07.003_bib0009","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0107724","article-title":"He YW. C-FLIP protects eosinophils from TNF-alpha-mediated cell death in vivo","volume":"9","author":"Gordy","year":"2014","journal-title":"Plos One"},{"issue":"1","key":"10.1016\/j.trsl.2023.07.003_bib0010","doi-asserted-by":"crossref","first-page":"5912","DOI":"10.1038\/s41467-021-25945-1","article-title":"OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice","volume":"12","author":"Schunke","year":"2021","journal-title":"Nat Commun"},{"issue":"2","key":"10.1016\/j.trsl.2023.07.003_bib0011","doi-asserted-by":"crossref","first-page":"e499","DOI":"10.1038\/cddis.2013.27","article-title":"EVER2 protein binds TRADD to promote TNF-alpha-induced apoptosis","volume":"4","author":"Gaud","year":"2013","journal-title":"Cell Death Dis"},{"issue":"2","key":"10.1016\/j.trsl.2023.07.003_bib0012","doi-asserted-by":"crossref","DOI":"10.1242\/jcs.208512","article-title":"Linear ubiquitination at a glance","volume":"132","author":"Spit","year":"2019","journal-title":"J Cell Sci"},{"issue":"1","key":"10.1016\/j.trsl.2023.07.003_bib0013","doi-asserted-by":"crossref","first-page":"e52702","DOI":"10.15252\/embr.202152702","article-title":"Bclaf1 regulates c-FLIP expression and protects cells from TNF-induced apoptosis and tissue injury","volume":"23","author":"Zhang","year":"2022","journal-title":"Embo Rep"},{"issue":"1","key":"10.1016\/j.trsl.2023.07.003_bib0014","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1111\/imr.12300","article-title":"Linear ubiquitination signals in adaptive immune responses","volume":"266","author":"Ikeda","year":"2015","journal-title":"Immunol Rev"},{"issue":"3","key":"10.1016\/j.trsl.2023.07.003_bib0015","doi-asserted-by":"crossref","first-page":"985","DOI":"10.1038\/s41418-020-00629-3","article-title":"Impaired RIPK1 ubiquitination sensitizes mice to TNF toxicity and inflammatory cell death","volume":"28","author":"Kist","year":"2021","journal-title":"Cell Death Differ"},{"issue":"9","key":"10.1016\/j.trsl.2023.07.003_bib0016","doi-asserted-by":"crossref","first-page":"773","DOI":"10.1038\/s41419-022-05206-9","article-title":"PP6 negatively modulates LUBAC-mediated M1-ubiquitination of RIPK1 and c-FLIP(L) to promote TNFalpha-mediated cell death","volume":"13","author":"Wu","year":"2022","journal-title":"Cell Death Dis"},{"issue":"2","key":"10.1016\/j.trsl.2023.07.003_bib0017","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1016\/j.molcel.2012.05.004","article-title":"A death effector domain chain DISC model reveals a crucial role for caspase-8 chain assembly in mediating apoptotic cell death","volume":"47","author":"Dickens","year":"2012","journal-title":"Mol Cell"},{"issue":"52","key":"10.1016\/j.trsl.2023.07.003_bib0018","doi-asserted-by":"crossref","first-page":"20062","DOI":"10.1074\/jbc.RA118.005449","article-title":"Linear ubiquitination of cFLIP induced by LUBAC contributes to TNFalpha-induced apoptosis","volume":"293","author":"Tang","year":"2018","journal-title":"J Biol Chem"},{"issue":"1","key":"10.1016\/j.trsl.2023.07.003_bib0019","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1002\/dmrr.1141","article-title":"The changing epidemiology of type 1 diabetes: why is it going through the roof?","volume":"27","author":"Vehik","year":"2011","journal-title":"Diabetes Metab Res Rev"},{"issue":"9911","key":"10.1016\/j.trsl.2023.07.003_bib0020","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1016\/S0140-6736(13)60591-7","article-title":"Type 1 diabetes","volume":"383","author":"Atkinson","year":"2014","journal-title":"Lancet"},{"issue":"9982","key":"10.1016\/j.trsl.2023.07.003_bib0021","doi-asserted-by":"crossref","first-page":"2107","DOI":"10.1016\/S0140-6736(14)61402-1","article-title":"Heart failure in diabetes: effects of anti-hyperglycaemic drug therapy","volume":"385","author":"Gilbert","year":"2015","journal-title":"Lancet"},{"key":"10.1016\/j.trsl.2023.07.003_bib0022","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2021.107916","article-title":"The mechanism of action of N-acetylcysteine (NAC): the emerging role of H(2)S and sulfane sulfur species","volume":"228","author":"Pedre","year":"2021","journal-title":"Pharmacol Ther"},{"issue":"4","key":"10.1016\/j.trsl.2023.07.003_bib0023","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s40256-018-0275-2","article-title":"A systematic review on the protective effect of N-Acetyl cysteine against diabetes-associated cardiovascular complications","volume":"18","author":"Dludla","year":"2018","journal-title":"Am J Cardiovasc Drugs"},{"issue":"4","key":"10.1016\/j.trsl.2023.07.003_bib0024","doi-asserted-by":"crossref","first-page":"927","DOI":"10.1111\/jvim.14357","article-title":"What's in a name? Classification of diabetes mellitus in veterinary medicine and why it matters","volume":"30","author":"Gilor","year":"2016","journal-title":"J Vet Intern Med"},{"issue":"2","key":"10.1016\/j.trsl.2023.07.003_bib0025","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1631\/jzus.B2200213","article-title":"Lyciumbarbarum polysaccharides ameliorate canine acute liver injury by reducing oxidative stress, protecting mitochondrial function, and regulating metabolic pathways","volume":"24","author":"Huang","year":"2023","journal-title":"J Zhejiang Univ Sci B"},{"issue":"3","key":"10.1016\/j.trsl.2023.07.003_bib0026","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1111\/j.1939-1676.1996.tb02042.x","article-title":"Basal and glucagon-stimulated plasma C-peptide concentrations in healthy dogs, dogs with diabetes mellitus, and dogs with hyperadrenocorticism","volume":"10","author":"Montgomery","year":"1996","journal-title":"J Vet Intern Med"},{"key":"10.1016\/j.trsl.2023.07.003_bib0027","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.lfs.2019.01.011","article-title":"Insulin analogs: glimpse on contemporary facts and future prospective","volume":"219","author":"Sharma","year":"2019","journal-title":"Life Sci"},{"key":"10.1016\/j.trsl.2023.07.003_bib0028","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/j.trsl.2019.12.001","article-title":"Salt-sensitive blood pressure rise in type 1 diabetes patients is accompanied by disturbed skin macrophage influx and lymphatic dilation-a proof-of-concept study","volume":"217","author":"Wenstedt","year":"2020","journal-title":"Transl Res"},{"key":"10.1016\/j.trsl.2023.07.003_bib0029","article-title":"Empagliflozin ameliorates diabetic cardiomyopathy via attenuating oxidative stress and improving mitochondrial function","volume":"2022","author":"Wang","year":"2022","journal-title":"Oxid Med Cell Longev"},{"issue":"2","key":"10.1016\/j.trsl.2023.07.003_bib0030","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.3390\/ijms24021132","article-title":"Streptozotocin-induced type 1 and 2 diabetes mellitus mouse models show different functional, cellular and molecular patterns of diabetic cardiomyopathy","volume":"24","author":"Marino","year":"2023","journal-title":"Int J Mol Sci"},{"key":"10.1016\/j.trsl.2023.07.003_bib0031","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.trsl.2019.01.005","article-title":"Mast cell-deficiency protects mice from streptozotocin-induced diabetic cardiomyopathy","volume":"208","author":"He","year":"2019","journal-title":"Transl Res"},{"issue":"11","key":"10.1016\/j.trsl.2023.07.003_bib0032","doi-asserted-by":"crossref","first-page":"1501","DOI":"10.1161\/CIRCRESAHA.120.315913","article-title":"Basic mechanisms of diabetic heart disease","volume":"126","author":"Ritchie","year":"2020","journal-title":"Circ Res"},{"issue":"2","key":"10.1016\/j.trsl.2023.07.003_bib0033","doi-asserted-by":"crossref","first-page":"79","DOI":"10.1016\/j.trsl.2007.11.005","article-title":"Tanshinone IIA protects neonatal rat cardiomyocytes from adriamycin-induced apoptosis","volume":"151","author":"Gao","year":"2008","journal-title":"Transl Res"},{"issue":"7","key":"10.1016\/j.trsl.2023.07.003_bib0034","doi-asserted-by":"crossref","first-page":"561","DOI":"10.1042\/CS20150204","article-title":"Impaired mitochondrial energy supply coupled to increased H2O2 emission under energy\/redox stress leads to myocardial dysfunction during Type I diabetes","volume":"129","author":"Tocchetti","year":"2015","journal-title":"Clin Sci (Lond)"},{"issue":"10","key":"10.1016\/j.trsl.2023.07.003_bib0035","doi-asserted-by":"crossref","first-page":"610","DOI":"10.1038\/nrm.2017.53","article-title":"The multifaceted roles of PARP1 in DNA repair and chromatin remodelling","volume":"18","author":"Ray","year":"2017","journal-title":"Nat Rev Mol Cell Biol"},{"issue":"6535","key":"10.1016\/j.trsl.2023.07.003_bib0036","doi-asserted-by":"crossref","first-page":"37","DOI":"10.1038\/376037a0","article-title":"Identification and inhibition of the ICE\/CED-3 protease necessary for mammalian apoptosis","volume":"376","author":"Nicholson","year":"1995","journal-title":"Nature"},{"key":"10.1016\/j.trsl.2023.07.003_bib0037","doi-asserted-by":"crossref","DOI":"10.1016\/j.dnarep.2019.102651","article-title":"PARP-1 and its associated nucleases in DNA damage response","volume":"81","author":"Wang","year":"2019","journal-title":"DNA Repair (Amst)"},{"issue":"23","key":"10.1016\/j.trsl.2023.07.003_bib0038","doi-asserted-by":"crossref","first-page":"9181","DOI":"10.3390\/ijms21239181","article-title":"NF-kappaB and disease","volume":"21","author":"Poma","year":"2020","journal-title":"Int J Mol Sci"},{"issue":"3","key":"10.1016\/j.trsl.2023.07.003_bib0039","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1016\/j.bbrc.2016.04.085","article-title":"Prolyl hydroxylase-1 regulates hepatocyte apoptosis in an NF-kappaB-dependent manner","volume":"474","author":"Fitzpatrick","year":"2016","journal-title":"Biochem Biophys Res Commun"},{"issue":"7","key":"10.1016\/j.trsl.2023.07.003_bib0040","doi-asserted-by":"crossref","first-page":"1789","DOI":"10.1089\/ars.2010.3769","article-title":"Disruption of hypoxia-inducible transcription factor-prolyl hydroxylase domain-1 (PHD-1-\/-) attenuates ex vivo myocardial ischemia\/reperfusion injury through hypoxia-inducible factor-1alpha transcription factor and its target genes in mice","volume":"15","author":"Adluri","year":"2011","journal-title":"Antioxid Redox Signal"},{"issue":"6","key":"10.1016\/j.trsl.2023.07.003_bib0041","doi-asserted-by":"crossref","first-page":"779","DOI":"10.1016\/j.ejca.2006.01.011","article-title":"NF-kappaB inhibition: a double-edged sword in cancer?","volume":"42","author":"Pikarsky","year":"2006","journal-title":"Eur J Cancer"},{"issue":"44","key":"10.1016\/j.trsl.2023.07.003_bib0042","doi-asserted-by":"crossref","first-page":"31728","DOI":"10.1074\/jbc.M113.495846","article-title":"Target specificity of the E3 ligase LUBAC for ubiquitin and NEMO relies on different minimal requirements","volume":"288","author":"Smit","year":"2013","journal-title":"J Biol Chem"},{"issue":"33","key":"10.1016\/j.trsl.2023.07.003_bib0043","doi-asserted-by":"crossref","DOI":"10.1073\/pnas.2123097119","article-title":"Reciprocal interplay between OTULIN-LUBAC determines genotoxic and inflammatory NF-kappaB signal responses","volume":"119","author":"Li","year":"2022","journal-title":"Proc Natl Acad Sci U S A"},{"issue":"7340","key":"10.1016\/j.trsl.2023.07.003_bib0044","doi-asserted-by":"crossref","first-page":"633","DOI":"10.1038\/nature09815","article-title":"SHARPIN is a component of the NF-kappaB-activating linear ubiquitin chain assembly complex","volume":"471","author":"Tokunaga","year":"2011","journal-title":"Nature"},{"issue":"3","key":"10.1016\/j.trsl.2023.07.003_bib0045","doi-asserted-by":"crossref","first-page":"203","DOI":"10.1517\/14728222.8.3.203","article-title":"TNF and congestive heart failure: therapeutic possibilities","volume":"8","author":"Muller-Ehmsen","year":"2004","journal-title":"Expert Opin Ther Targets"},{"issue":"4","key":"10.1016\/j.trsl.2023.07.003_bib0046","doi-asserted-by":"crossref","first-page":"H934","DOI":"10.1152\/ajpheart.00493.2011","article-title":"Mathematical modeling mechanisms of arrhythmias in transgenic mouse heart overexpressing TNF-alpha","volume":"302","author":"Petkova-Kirova","year":"2012","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"2","key":"10.1016\/j.trsl.2023.07.003_bib0047","doi-asserted-by":"crossref","first-page":"H832","DOI":"10.1152\/ajpheart.00178.2005","article-title":"Pentoxifylline attenuates cardiac dysfunction and reduces TNF-alpha level in ischemic-reperfused heart","volume":"289","author":"Zhang","year":"2005","journal-title":"Am J Physiol Heart Circ Physiol"},{"issue":"23","key":"10.1016\/j.trsl.2023.07.003_bib0048","first-page":"8454","article-title":"MiRNA-130a improves cardiac function by down-regulating TNF-alpha expression in a rat model of heart failure","volume":"22","author":"Jiang","year":"2018","journal-title":"Eur Rev Med Pharmacol Sci"},{"issue":"12","key":"10.1016\/j.trsl.2023.07.003_bib0049","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.3000967","article-title":"Transmembrane tumor necrosis factor alpha attenuates pressure-overload cardiac hypertrophy via tumor necrosis factor receptor 2","volume":"18","author":"Miao","year":"2020","journal-title":"Plos Biol"},{"issue":"6","key":"10.1016\/j.trsl.2023.07.003_bib0050","doi-asserted-by":"crossref","first-page":"362","DOI":"10.1038\/nri3834","article-title":"Regulation of tumour necrosis factor signalling: live or let die","volume":"15","author":"Brenner","year":"2015","journal-title":"Nat Rev Immunol"},{"issue":"2","key":"10.1016\/j.trsl.2023.07.003_bib0051","doi-asserted-by":"crossref","first-page":"158","DOI":"10.1161\/CIRCULATIONAHA.122.059304","article-title":"Cannabinoid receptor 2-Centric molecular feedback loop drives necroptosis in diabetic heart injuries","volume":"147","author":"Gao","year":"2023","journal-title":"Circulation"},{"issue":"11","key":"10.1016\/j.trsl.2023.07.003_bib0052","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1007\/s13238-020-00810-x","article-title":"RIP1-dependent linear and nonlinear recruitments of caspase-8 and RIP3 respectively to necrosome specify distinct cell death outcomes","volume":"12","author":"Li","year":"2021","journal-title":"Protein Cell"},{"issue":"2","key":"10.1016\/j.trsl.2023.07.003_bib0053","doi-asserted-by":"crossref","first-page":"708","DOI":"10.1016\/j.apsb.2021.10.005","article-title":"Ferroptosis is essential for diabetic cardiomyopathy and is prevented by sulforaphane via AMPK\/NRF2 pathways","volume":"12","author":"Wang","year":"2022","journal-title":"Acta Pharm Sin B"},{"issue":"2","key":"10.1016\/j.trsl.2023.07.003_bib0054","doi-asserted-by":"crossref","first-page":"1667","DOI":"10.3390\/ijms24021667","article-title":"ATF3\/SPI1\/SLC31A1 signaling promotes cuproptosis induced by advanced glycosylation end products in diabetic myocardial injury","volume":"24","author":"Huo","year":"2023","journal-title":"Int J Mol Sci"},{"issue":"1","key":"10.1016\/j.trsl.2023.07.003_bib0055","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.apsb.2021.08.026","article-title":"Preliminary evidence for the presence of multiple forms of cell death in diabetes cardiomyopathy","volume":"12","author":"Wei","year":"2022","journal-title":"Acta Pharm Sin B"}],"container-title":["Translational Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193152442300110X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S193152442300110X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,10,30]],"date-time":"2025-10-30T12:48:17Z","timestamp":1761828497000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S193152442300110X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,12]]},"references-count":55,"alternative-id":["S193152442300110X"],"URL":"https:\/\/doi.org\/10.1016\/j.trsl.2023.07.003","relation":{},"ISSN":["1931-5244"],"issn-type":[{"value":"1931-5244","type":"print"}],"subject":[],"published":{"date-parts":[[2023,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"N-acetylcysteine combined with insulin attenuates myocardial injury in canines with type 1 diabetes mellitus by modulating TNF-\u03b1-mediated apoptotic pathways and affecting linear ubiquitination","name":"articletitle","label":"Article Title"},{"value":"Translational Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trsl.2023.07.003","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}