{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T03:51:00Z","timestamp":1791517860762,"version":"4.3.4"},"reference-count":23,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2026,12,1]],"date-time":"2026-12-01T00:00:00Z","timestamp":1796083200000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"funder":[{"DOI":"10.13039\/501100001411","name":"Indian Council of Medical Research","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100001411","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","translationalres.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Translational Research"],"published-print":{"date-parts":[[2026,12]]},"DOI":"10.1016\/j.trsl.2026.10.002","type":"journal-article","created":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T06:59:21Z","timestamp":1791269961000},"page":"99-107","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":0,"special_numbering":"C","title":["Identification of plasma immune markers associated with latent tuberculosis conversion in HIV-infected individuals who received isoniazid preventive therapy"],"prefix":"10.1016","volume":"298","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2969-2621","authenticated-orcid":false,"given":"Nathella Pavan","family":"Kumar","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guruprashath","family":"Mohan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agalya","family":"Vanamudhu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sivasubarmanian","family":"K","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kannan","family":"T","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Y Savari","family":"Silvester","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bubby S","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Janakiram","family":"M","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vinod","family":"Kumar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijila","family":"S","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"family":"Sekar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kuralmozhi","family":"R","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Subash","family":"Babu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Syed","family":"Hissar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"11","key":"10.1016\/j.trsl.2026.10.002_bib0001","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0313306","article-title":"Human-immunodeficiency virus infection associated with the impaired Th1 and pro-inflammatory cytokine response in latent tuberculosis-infected individuals: a comparative cross-sectional study","volume":"19","author":"Girmay","year":"2024","journal-title":"PLoS One"},{"key":"10.1016\/j.trsl.2026.10.002_bib0002","year":"2024","journal-title":"Tuberculosis"},{"key":"10.1016\/j.trsl.2026.10.002_bib0003","year":"2023","journal-title":"Global Tuberculosis Report"},{"key":"10.1016\/j.trsl.2026.10.002_bib0004","article-title":"Tuberculosis and HIV coinfection. Cold Spring Harb","volume":"5","author":"Bruchfeld","year":"2015","journal-title":"Perspect. Med."},{"issue":"1","key":"10.1016\/j.trsl.2026.10.002_bib0006","doi-asserted-by":"crossref","first-page":"19","DOI":"10.1186\/s42522-025-00144-w","article-title":"Advancement in diagnostic approaches for latent tuberculosis: distinguishing recent from remote infections","volume":"7","author":"Ding","year":"2025","journal-title":"One Health Outlook"},{"issue":"1","key":"10.1016\/j.trsl.2026.10.002_bib0009","first-page":"58","article-title":"From immunology to artificial intelligence: revolutionizing latent tuberculosis infection diagnosis with machine learning","volume":"10","author":"Li","year":"2023","journal-title":"Mil Med Res"},{"key":"10.1016\/j.trsl.2026.10.002_bib0005","first-page":"1","article-title":"Cytokines and their role in health and disease: a brief overview","volume":"4","author":"Arunabha","year":"2016","journal-title":"MOJ Immunol"},{"key":"10.1016\/j.trsl.2026.10.002_bib0025","series-title":"Cytokine Effector Functions in Tissues","isbn-type":"print","doi-asserted-by":"crossref","first-page":"3","DOI":"10.1016\/B978-0-12-804214-4.00019-1","article-title":"Introduction to cytokines as Tissue Regulators in health and disease","author":"Foti","year":"2017","ISBN":"https:\/\/id.crossref.org\/isbn\/9780128042144"},{"issue":"1","key":"10.1016\/j.trsl.2026.10.002_bib0010","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1089\/088282404322875502","article-title":"Increased plasma transforming growth factor-beta1 is associated with disease progression in HIV-1-infected patients","volume":"17","author":"Wierci\u0144ska-Drapalo","year":"2004","journal-title":"Viral Immunol"},{"issue":"6","key":"10.1016\/j.trsl.2026.10.002_bib0011","doi-asserted-by":"crossref","first-page":"839","DOI":"10.3390\/v17060839","article-title":"HIV, inflammation, and immunometabolism: a model of the Inflammatory theory of disease","volume":"17","author":"Teer","year":"2025","journal-title":"Viruses"},{"key":"10.1016\/j.trsl.2026.10.002_bib0012","doi-asserted-by":"crossref","DOI":"10.3389\/fcimb.2024.1458195","article-title":"Vascular endothelial growth factor A: friend or foe in the pathogenesis of HIV and SARS-CoV-2 infections?","volume":"14","author":"van der Mescht","year":"2025","journal-title":"Front Cell Infect Microbiol"},{"issue":"5","key":"10.1016\/j.trsl.2026.10.002_bib0013","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1089\/aid.2011.0213","article-title":"Immune activation in the pathogenesis of treated chronic HIV disease: a workshop summary","volume":"28","author":"Plaeger","year":"2012","journal-title":"AIDS Res Hum Retroviruses"},{"key":"10.1016\/j.trsl.2026.10.002_bib0014","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1111\/odi.12390","article-title":"HIV-TB co-infection: mechanisms that drive reactivation of mycobacterium tuberculosis in HIV infection","volume":"22","author":"Ahmed","year":"2016","journal-title":"Oral Dis"},{"issue":"7","key":"10.1016\/j.trsl.2026.10.002_bib0015","doi-asserted-by":"crossref","first-page":"1065","DOI":"10.1097\/QAD.0000000000003523","article-title":"Latent tuberculosis is associated with heightened levels of pro-and anti-inflammatory cytokines among Kenyan men and women living with HIV on long-term antiretroviral therapy","volume":"37","author":"Temu","year":"2023","journal-title":"AIDS"},{"issue":"6","key":"10.1016\/j.trsl.2026.10.002_bib0017","doi-asserted-by":"crossref","first-page":"1330","DOI":"10.3390\/v15061330","article-title":"Unique profile of proinflammatory cytokines in plasma of drug-na\u00efve individuals with advanced HIV\/TB Co-infection","volume":"15","author":"Nosik","year":"2023","journal-title":"Viruses"},{"issue":"1","key":"10.1016\/j.trsl.2026.10.002_bib0016","doi-asserted-by":"crossref","DOI":"10.1038\/s41598-019-54803-w","article-title":"Plasma chemokines are biomarkers of disease severity, higher bacterial burden and delayed sputum culture conversion in pulmonary tuberculosis","volume":"9","author":"Kumar","year":"2019","journal-title":"Sci Rep"},{"issue":"2","key":"10.1016\/j.trsl.2026.10.002_bib0018","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1093\/cid\/ciy823","article-title":"Plasma biomarkers to detect prevalent or predict progressive tuberculosis associated with Human Immunodeficiency Virus-1","volume":"69","author":"Lesosky","year":"2019","journal-title":"Clin Infect Dis"},{"issue":"3","key":"10.1016\/j.trsl.2026.10.002_bib0019","doi-asserted-by":"crossref","first-page":"696","DOI":"10.1093\/infdis\/jiae365","article-title":"Plasma immune biomarkers predictive of progression to active tuberculosis in household contacts of patients with tuberculosis","volume":"231","author":"Rajamanickam","year":"2025","journal-title":"J Infect Dis"},{"issue":"8","key":"10.1016\/j.trsl.2026.10.002_bib0024","doi-asserted-by":"crossref","DOI":"10.1016\/j.isci.2023.107425","article-title":"Comparative immune responses to mycobacterium tuberculosis in people with latent infection or sterilizing protection","volume":"26","author":"Jalbert","year":"2023","journal-title":"IScience"},{"issue":"9","key":"10.1016\/j.trsl.2026.10.002_bib0020","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1016\/S2213-8587(21)00172-8","article-title":"Long-term population-based trends in the incidence of cardiovascular disease in individuals with type 1 diabetes from Finland: a retrospective, nationwide, cohort study","volume":"9","author":"Harjutsalo","year":"2021","journal-title":"Lancet Diabetes Endocrinol"},{"issue":"5","key":"10.1016\/j.trsl.2026.10.002_bib0021","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/j.jcjd.2016.02.014","article-title":"Type 2 diabetes: model of factors associated with glycemic control","volume":"40","author":"Aghili","year":"2016","journal-title":"Can J Diabetes"},{"issue":"2","key":"10.1016\/j.trsl.2026.10.002_bib0022","doi-asserted-by":"crossref","first-page":"613","DOI":"10.4049\/jimmunol.1601340","article-title":"T cell-derived IL-10 impairs host resistance to mycobacterium tuberculosis infection","volume":"199","author":"Moreira-Teixeira","year":"2017","journal-title":"J Immunol"},{"key":"10.1016\/j.trsl.2026.10.002_bib0023","first-page":"3","article-title":"Mycobacterium tuberculosis resisters despite HIV exhibit activated T cells and macrophages in their pulmonary alveoli","author":"Schurr","year":"2024","journal-title":"Research Square"}],"container-title":["Translational Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524426002124?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1931524426002124?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T03:35:09Z","timestamp":1791516909000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1931524426002124"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,12]]},"references-count":23,"alternative-id":["S1931524426002124"],"URL":"https:\/\/doi.org\/10.1016\/j.trsl.2026.10.002","relation":{},"ISSN":["1931-5244"],"issn-type":[{"value":"1931-5244","type":"print"}],"subject":[],"published":{"date-parts":[[2026,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Identification of plasma immune markers associated with latent tuberculosis conversion in HIV-infected individuals who received isoniazid preventive therapy","name":"articletitle","label":"Article Title"},{"value":"Translational Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.trsl.2026.10.002","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 Elsevier Inc. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}]}}