{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,9]],"date-time":"2026-05-09T10:38:58Z","timestamp":1778323138206,"version":"3.51.4"},"reference-count":57,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2015,4,1]],"date-time":"2015-04-01T00:00:00Z","timestamp":1427846400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Bavarian Ministry for Health and Care"},{"name":"Robert-Koch-Institute"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ticks and Tick-borne Diseases"],"published-print":{"date-parts":[[2015,4]]},"DOI":"10.1016\/j.ttbdis.2015.02.008","type":"journal-article","created":{"date-parts":[[2015,3,10]],"date-time":"2015-03-10T06:06:26Z","timestamp":1425967586000},"page":"344-351","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":35,"title":["NGS population genetics analyses reveal divergent evolution of a Lyme Borreliosis agent in Europe and Asia"],"prefix":"10.1016","volume":"6","author":[{"given":"Fanny","family":"Gatzmann","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dirk","family":"Metzler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stefan","family":"Krebs","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Helmut","family":"Blum","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andreas","family":"Sing","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ai","family":"Takano","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hiroki","family":"Kawabata","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Volker","family":"Fingerle","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gabriele","family":"Margos","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"No\u00e9mie S.","family":"Becker","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.ttbdis.2015.02.008_bib0005","first-page":"1","article-title":"Evolution and distribution of the ospC Gene, a transferable serotype determinant of Borrelia burgdorferi","author":"Barbour","year":"2010","journal-title":"MBio"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0010","doi-asserted-by":"crossref","first-page":"D36","DOI":"10.1093\/nar\/gks1195","article-title":"GenBank","volume":"41","author":"Benson","year":"2013","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0015","first-page":"10","article-title":"Galaxy: a web-based genome analysis tool for experimentalists","author":"Blankenberg","year":"2010","journal-title":"Curr. Protoc. Mol. Biol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0020","doi-asserted-by":"crossref","first-page":"5713","DOI":"10.1128\/JB.01360-12","article-title":"Whole-genome sequencing of Borrelia garinii BgVir, isolated from Taiga ticks (Ixodes persulcatus)","volume":"194","author":"Brenner","year":"2012","journal-title":"J. Bacteriol."},{"issue":"3","key":"10.1016\/j.ttbdis.2015.02.008_bib0025","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1534\/genetics.106.063305","article-title":"Inference of bacterial microevolution using multilocus sequence data","volume":"175","author":"Didelot","year":"2007","journal-title":"Genetics"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0030","doi-asserted-by":"crossref","first-page":"214","DOI":"10.1186\/1471-2148-7-214","article-title":"BEAST: Bayesian evolutionary analysis by sampling trees","volume":"7","author":"Drummond","year":"2007","journal-title":"BMC Evol. Biol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0035","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1128\/AEM.01674-08","article-title":"Differential role of passerine birds in distribution of Borrelia spirochetes, based on data from ticks collected from birds during the postbreeding migration period in Central Europe","volume":"75","author":"Dubska","year":"2009","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0040","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1016\/j.ijmm.2007.05.002","article-title":"Epidemiological aspects and molecular characterization of Borrelia burgdorferi s.l. from southern Germany with special respect to the new species Borrelia spielmanii sp. nov.","volume":"298","author":"Fingerle","year":"2008","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0045","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1093\/genetics\/133.3.693","article-title":"Statistical tests of neutrality of mutations","volume":"133","author":"Fu","year":"1993","journal-title":"Genetics"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0050","doi-asserted-by":"crossref","first-page":"202","DOI":"10.1186\/1756-3305-6-202","article-title":"Borrelia burgdorferi sensu lato prevalence in tick populations in Estonia","volume":"6","author":"Geller","year":"2013","journal-title":"Parasit. Vectors"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0055","doi-asserted-by":"crossref","first-page":"1451","DOI":"10.1101\/gr.4086505","article-title":"Galaxy: a platform for interactive large-scale genome analysis","volume":"15","author":"Giardine","year":"2005","journal-title":"Genome Res."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0060","doi-asserted-by":"crossref","first-page":"6038","DOI":"10.1093\/nar\/gkh953","article-title":"Comparative analysis of the Borrelia garinii genome","volume":"32","author":"Gl\u00f6ckner","year":"2004","journal-title":"Nucleic Acids Res."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0065","doi-asserted-by":"crossref","first-page":"R86","DOI":"10.1186\/gb-2010-11-8-r86","article-title":"Galaxy: a comprehensive approach for supporting accessible, reproducible, and transparent computational research in the life sciences","volume":"11","author":"Goecks","year":"2010","journal-title":"Genome Biol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0070","doi-asserted-by":"crossref","first-page":"e73066","DOI":"10.1371\/journal.pone.0073066","article-title":"Multilocus sequence typing of Borrelia burgdorferi suggests existence of lineages with differential pathogenic properties in humans","volume":"8","author":"Hanincova","year":"2013","journal-title":"PLOS ONE"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0075","doi-asserted-by":"crossref","first-page":"2825","DOI":"10.1128\/AEM.69.5.2825-2830.2003","article-title":"Association of Borrelia garinii and B. valaisiana with songbirds in Slovakia","volume":"69","author":"Hanincova","year":"2003","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0080","doi-asserted-by":"crossref","first-page":"1169","DOI":"10.1128\/JCM.39.3.1169-1171.2001","article-title":"Transmission of Borrelia garinii OspA serotype 4 to BALB\/c mice by Ixodes ricinus ticks collected in the field","volume":"39","author":"Hu","year":"2001","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0085","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1093\/genetics\/111.1.147","article-title":"Statistical properties of the number of recombination events in the history of a sample of DNA sequences","volume":"111","author":"Hudson","year":"1985","journal-title":"Genetics"},{"issue":"2","key":"10.1016\/j.ttbdis.2015.02.008_bib0090","doi-asserted-by":"crossref","first-page":"254","DOI":"10.1093\/molbev\/msj030","article-title":"Application of phylogenetic networks in evolutionary studies","volume":"23","author":"Huson","year":"2006","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0095","doi-asserted-by":"crossref","first-page":"4735","DOI":"10.1128\/JCM.40.12.4735-4737.2002","article-title":"Apodemus species mice are reservoir hosts of Borrelia garinii OspA serotype 4 in Switzerland","volume":"40","author":"Huegli","year":"2002","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0100","doi-asserted-by":"crossref","first-page":"1157","DOI":"10.1093\/genetics\/151.3.1157","article-title":"A method for estimating nucleotide diversity from AFLP data","volume":"151","author":"Innan","year":"1999","journal-title":"Genetics"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0105","doi-asserted-by":"crossref","first-page":"6660","DOI":"10.1128\/JB.01844-12","article-title":"Genome sequence of Borrelia garinii strain NMJW1, isolated from China","volume":"194","author":"Jiang","year":"2012","journal-title":"J. Bacteriol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0110","series-title":"Lyme Borreliosis: Biology, Epidemiology and Control","article-title":"Ecology of Borrelia burgdorferi sensu lato in Russia","author":"Korenberg","year":"2002"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0115","doi-asserted-by":"crossref","first-page":"660","DOI":"10.1038\/nrmicro1475","article-title":"Fundamental processes in the evolutionary ecology of Lyme borreliosis","volume":"4","author":"Kurtenbach","year":"2006","journal-title":"Nat. Rev. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0120","doi-asserted-by":"crossref","first-page":"298","DOI":"10.1186\/1471-2105-6-298","article-title":"Kalign \u2013 an accurate and fast multiple sequence alignment algorithm","volume":"6","author":"Lassmann","year":"2005","journal-title":"BMC Bioinformatics"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0125","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1128\/MMBR.69.1.101-123.2005","article-title":"Initiation of protein synthesis in bacteria","volume":"69","author":"Laursen","year":"2005","journal-title":"Microbiol. Mol. Biol. Rev."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0130","doi-asserted-by":"crossref","first-page":"2078","DOI":"10.1093\/bioinformatics\/btp352","article-title":"The sequence alignment\/map format and SAMtools","volume":"25","author":"Li","year":"2009","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0135","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1101\/gr.097261.109","article-title":"De novo assembly of human genomes with massively parallel short read sequencing","volume":"20","author":"Li","year":"2010","journal-title":"Genome Res."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0140","series-title":"Learning Python","author":"Lutz","year":"2009"},{"issue":"12","key":"10.1016\/j.ttbdis.2015.02.008_bib0145","doi-asserted-by":"crossref","first-page":"3965","DOI":"10.1128\/JCM.37.12.3965-3970.1999","article-title":"Genetic analysis of Borrelia garinii OspA serotype 4 strains associated with neuroborreliosis: evidence for extensive genetic homogeneity","volume":"37","author":"Marconi","year":"1999","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0150","doi-asserted-by":"crossref","first-page":"1952","DOI":"10.1017\/S0031182012000741","article-title":"Phylogeography of Lyme borreliosis-group spirochetes and methicillin-resistant Staphylococcus aureus","volume":"139","author":"Margos","year":"2012","journal-title":"Parasitology"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0155","doi-asserted-by":"crossref","first-page":"5410","DOI":"10.1128\/AEM.00116-09","article-title":"A new Borrelia species defined by multilocus sequence analysis of housekeeping genes","volume":"75","author":"Margos","year":"2009","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0160","doi-asserted-by":"crossref","first-page":"4284","DOI":"10.1099\/ijs.0.052001-0","article-title":"Borrelia bavariensis sp. nov. is widely distributed in Europe and Asia","volume":"63","author":"Margos","year":"2013","journal-title":"Int. J. Syst. Evol. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0165","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/j.ijmm.2004.09.008","article-title":"Characterization of Borrelia burgdorferi sensu lato isolated in Moscow province-a sympatric region for Ixodes ricinus and Ixodes persulcatus","volume":"294","author":"Masuzawa","year":"2005","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0170","series-title":"Lyme Borreliosis: Biology, Epidemiology and Control","first-page":"201","article-title":"Ecology of Borrelia burgdorferi sensu lato in Japan and East Asia","author":"Miyamoto","year":"2002"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0175","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1186\/1471-2164-14-693","article-title":"Inter- and intra-specific pan-genomes of Borrelia burgdorferi sensu lato: genome stability and adaptive radiation","volume":"14","author":"Mongodin","year":"2013","journal-title":"BMC Genomics"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0180","doi-asserted-by":"crossref","first-page":"275","DOI":"10.1016\/j.ttbdis.2013.02.004","article-title":"Multilocus sequence analysis of Borrelia burgdorferi s.l. in Russia","volume":"4","author":"Mukhacheva","year":"2013","journal-title":"Ticks Tick Borne Dis."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0185","series-title":"Molecular Evolutionnary Genetics","author":"Nei","year":"1987"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0190","doi-asserted-by":"crossref","first-page":"165","DOI":"10.1016\/S0076-6879(02)58088-5","article-title":"Borrelia burgdorferi gene expression profiling with membrane-based arrays","volume":"358","author":"Ojaimi","year":"2002","journal-title":"Methods Enzymol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0195","doi-asserted-by":"crossref","first-page":"457","DOI":"10.1016\/j.cell.2004.10.027","article-title":"TROSPA, an Ixodes scapularis receptor for Borrelia burgdorferi","volume":"119","author":"Pal","year":"2004","journal-title":"Cell"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0200","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1093\/bioinformatics\/btp696","article-title":"pegas: an R package for population genetics with an integrated-modular approach","volume":"26","author":"Paradis","year":"2010","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0205","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1093\/bioinformatics\/btg412","article-title":"APE: analyses of phylogenetics and evolution in R language","volume":"20","author":"Paradis","year":"2004","journal-title":"Bioinformatics"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0210","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/j.ijmm.2004.08.002","article-title":"Comparison of growth of Borrelia afzelii, B. garinii, and B. burgdorferi sensu stricto in MKP and BSK-II medium","volume":"294","author":"Ruzi\u0107-Sablji\u0107","year":"2004","journal-title":"Int. J. Med. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0215","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/j.ttbdis.2012.08.004","article-title":"High prevalence of genetically diverse Borrelia bavariensis-like strains in Ixodes persulcatus from Selenge Aimag, Mongolia","volume":"4","author":"Scholz","year":"2013","journal-title":"Ticks Tick Borne Dis."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0220","doi-asserted-by":"crossref","first-page":"382","DOI":"10.1128\/JCM.38.1.382-388.2000","article-title":"Temporal changes in outer surface proteins A and C of the Lyme disease-associated spirochete. Borrelia burgdorferi, during the chain of infection in ticks and mice","volume":"38","author":"Schwan","year":"2000","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0225","doi-asserted-by":"crossref","first-page":"3518","DOI":"10.1128\/IAI.67.7.3518-3524.1999","article-title":"Four clones of Borrelia burgdorferi sensu stricto cause invasive infection in humans","volume":"67","author":"Seinost","year":"1999","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0230","doi-asserted-by":"crossref","first-page":"952","DOI":"10.3201\/eid1306.070224","article-title":"European hedgehogs as hosts for Borrelia spp., Germany","volume":"13","author":"Skuballa","year":"2007","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0235","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/j.1469-0691.2010.03175.x","article-title":"Lyme borreliosis: clinical case definitions for diagnosis and management in Europe","volume":"17","author":"Stanek","year":"2011","journal-title":"Clin. Microbiol. Infect."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0240","doi-asserted-by":"crossref","first-page":"450","DOI":"10.1097\/QCO.0b013e32832ee880","article-title":"Lyme borreliosis: a European perspective on diagnosis and clinical management","volume":"22","author":"Stanek","year":"2009","journal-title":"Curr. Opin. Infect. Dis."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0245","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1093\/genetics\/123.3.585","article-title":"Statistical method for testing the neutral mutation hypothesis by DNA polymorphism","volume":"123","author":"Tajima","year":"1989","journal-title":"Genetics"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0250","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1128\/JCM.02544-10","article-title":"Multilocus sequence typing implicates rodents as the main reservoir host of human-pathogenic Borrelia garinii in Japan","volume":"49","author":"Takano","year":"2011","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0255","doi-asserted-by":"crossref","first-page":"1289","DOI":"10.1128\/AEM.01060-07","article-title":"Blackbirds and song thrushes constitute a key reservoir of Borrelia garinii, the causative agent of borreliosis in Central Europe","volume":"74","author":"Taragel\u2019ova","year":"2008","journal-title":"Appl. Environ. Microbiol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0260","doi-asserted-by":"crossref","first-page":"15","DOI":"10.1093\/genetics\/151.1.15","article-title":"Genetic diversity of ospC in a local population of Borrelia burgdorferi sensu stricto","volume":"151","author":"Wang","year":"1999","journal-title":"Genetics"},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0265","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1007\/BF02456135","article-title":"Diversity of OspA and OspC among cerebrospinal fluid isolates of Borrelia burgdorferi sensu lato from patients with neuroborreliosis in Germany","volume":"184","author":"Wilske","year":"1996","journal-title":"Med. Microbiol. Immunol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0270","doi-asserted-by":"crossref","first-page":"1358","DOI":"10.1086\/592279","article-title":"Borrelia burgdorferi genotype predicts the capacity for hematogenous dissemination during early Lyme disease","volume":"198","author":"Wormser","year":"2008","journal-title":"J. Infect. Dis."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0275","doi-asserted-by":"crossref","first-page":"100","DOI":"10.1128\/IAI.01008-09","article-title":"Characterization of the highly regulated antigen BBA05 in the enzootic cycle of Borrelia burgdorferi","volume":"78","author":"Xu","year":"2010","journal-title":"Infect. Immun."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0280","doi-asserted-by":"crossref","first-page":"1586","DOI":"10.1093\/molbev\/msm088","article-title":"PAML 4, phylogenetic analysis by maximum likelihood","volume":"24","author":"Yang","year":"2007","journal-title":"Mol. Biol. Evol."},{"key":"10.1016\/j.ttbdis.2015.02.008_bib0285","doi-asserted-by":"crossref","first-page":"821","DOI":"10.1101\/gr.074492.107","article-title":"Velvet: algorithms for de novo short read assembly using de Bruijn graphs","volume":"18","author":"Zerbino","year":"2008","journal-title":"Genome Res."}],"container-title":["Ticks and Tick-borne Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877959X15000345?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877959X15000345?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2022,5,1]],"date-time":"2022-05-01T19:54:21Z","timestamp":1651434861000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1877959X15000345"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,4]]},"references-count":57,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2015,4]]}},"alternative-id":["S1877959X15000345"],"URL":"https:\/\/doi.org\/10.1016\/j.ttbdis.2015.02.008","relation":{},"ISSN":["1877-959X"],"issn-type":[{"value":"1877-959X","type":"print"}],"subject":[],"published":{"date-parts":[[2015,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"NGS population genetics analyses reveal divergent evolution of a Lyme Borreliosis agent in Europe and Asia","name":"articletitle","label":"Article Title"},{"value":"Ticks and Tick-borne Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ttbdis.2015.02.008","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2015 Elsevier GmbH. All rights reserved.","name":"copyright","label":"Copyright"}]}}