{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:05:40Z","timestamp":1787313940926,"version":"build-2736575974"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100004326","name":"Bayer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004326","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100004702","name":"Baxter International","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004702","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ticks and Tick-borne Diseases"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1016\/j.ttbdis.2018.09.011","type":"journal-article","created":{"date-parts":[[2018,9,25]],"date-time":"2018-09-25T22:24:17Z","timestamp":1537914257000},"page":"166-169","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"title":["Immunoblot reactivity at follow-up in treated patients with Lyme neuroborreliosis and healthy controls"],"prefix":"10.1016","volume":"10","author":[{"given":"R.","family":"Dersch","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Sarnes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Maul","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Minakowski","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"T.","family":"Hottenrott","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"O.","family":"Stich","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"S.","family":"Rauer","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ttbdis.2018.09.011_bib0005","doi-asserted-by":"crossref","first-page":"2572","DOI":"10.1007\/s00415-015-7891-4","article-title":"Quality of life, fatigue, depression and cognitive impairment in Lyme neuroborreliosis","volume":"262","author":"Dersch","year":"2015","journal-title":"J. Neurol."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0010","doi-asserted-by":"crossref","first-page":"3602","DOI":"10.1128\/JCM.43.8.3602-3609.2005","article-title":"Improvement of Lyme borreliosis serodiagnosis by a newly developed recombinant immunoglobulin G (IgG) and IgM line immunoblot assay and addition of VlsE and DbpA homologues","volume":"43","author":"Goettner","year":"2005","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0015","first-page":"1338","article-title":"Lyme disease: a multisystem infection that affects the nervous system","volume":"18","author":"Halperin","year":"2012","journal-title":"Contin. Minneap. Minn."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0020","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1212\/01.wnl.0000265517.66976.28","article-title":"Practice parameter: treatment of nervous system Lyme disease (an evidence-based review): report of the quality standards Subcommittee of the American Academy of Neurology","volume":"69","author":"Halperin","year":"2007","journal-title":"Neurology"},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0025","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1128\/JCM.32.6.1519-1525.1994","article-title":"Serological follow-up after treatment of patients with erythema migrans and neuroborreliosis","volume":"32","author":"Hammers-Berggren","year":"1994","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0030","doi-asserted-by":"crossref","first-page":"774","DOI":"10.1128\/JCM.35.3.774-776.1997","article-title":"Temporal study of immunoglobin M seroreactivity to Borrelia burgdorferi in patients treated for Lyme borreliosis","volume":"35","author":"Hilton","year":"1997","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0035","doi-asserted-by":"crossref","first-page":"697","DOI":"10.1007\/s100960050381","article-title":"Incidence of Lyme borreliosis in the W\u00fcrzburg region of Germany","volume":"18","author":"Huppertz","year":"1999","journal-title":"Eur. J. Clin. Microbiol. Infect. Dis. Off. Publ. Eur. Soc. Clin. Microbiol."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0040","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1007\/s004150050214","volume":"245","author":"Kaiser","year":"1998","journal-title":"Neuroborreliosis J. Neurol."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0045","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1086\/322669","article-title":"Persistence of immunoglobulin M or immunoglobulin G antibody responses to Borrelia burgdorferi 10-20 years after active Lyme disease","volume":"33","author":"Kalish","year":"2001","journal-title":"Clin. Infect. Dis. Off. Publ. Infect. Dis. Soc. Am."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0050","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1186\/s12879-016-1468-4","article-title":"The diagnostic accuracy of serological tests for Lyme borreliosis in Europe: a systematic review and meta-analysis","volume":"16","author":"Leeflang","year":"2016","journal-title":"BMC Infect. Dis."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0055","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1111\/j.1468-1331.2009.02862.x","article-title":"EFNS guidelines on the diagnosis and management of European Lyme neuroborreliosis","volume":"17","author":"Mygland","year":"2010","journal-title":"Eur. J. Neurol."},{"issue":"Suppl. 33","key":"10.1016\/j.ttbdis.2018.09.011_bib0060","doi-asserted-by":"crossref","first-page":"22","DOI":"10.1016\/S1438-4221(02)80005-4","article-title":"Foci of tick-borne diseases in southwest Germany","volume":"291","author":"Oehme","year":"2002","journal-title":"Int. J. Med. Microbiol. IJMM"},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0065","first-page":"343","article-title":"Bannwarth\u2019s syndrome and the enlarged neurological spectrum of arthropod-borne borreliosis","volume":"263","author":"Pfister","year":"1987","journal-title":"Zentralblatt F\u00fcr Bakteriol. Mikrobiol. Hyg. Ser. Med. Microbiol. Infect. Dis. Virol. Parasitol."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0070","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1128\/JCM.36.4.857-861.1998","article-title":"Enzyme-linked immunosorbent assay using recombinant OspC and the internal 14-kDa flagellin fragment for serodiagnosis of early Lyme disease","volume":"36","author":"Rauer","year":"1998","journal-title":"J. Clin. Microbiol."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0075","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.ttbdis.2013.10.010","article-title":"Trends in surveillance data of human Lyme borreliosis from six federal states in eastern Germany, 2009\u20132012","volume":"5","author":"Wilking","year":"2014","journal-title":"Ticks Tick-Borne Dis."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0080","doi-asserted-by":"crossref","first-page":"107","DOI":"10.3201\/eid2101.140009","article-title":"Antibodies against Borrelia burgdorferi sensu lato among Adults, Germany, 2008\u20132011","volume":"21","author":"Wilking","year":"2015","journal-title":"Emerg. Infect. Dis."},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0085","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1007\/BF00579624","article-title":"Recombinant immunoblot in the serodiagnosis of Lyme borreliosis. Comparison with indirect immunofluorescence and enzyme-linked immunosorbent assay","volume":"182","author":"Wilske","year":"1993","journal-title":"Med. Microbiol. Immunol. (Berl.)"},{"key":"10.1016\/j.ttbdis.2018.09.011_bib0090","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1111\/j.1574-695X.2006.00139.x","article-title":"Microbiological and serological diagnosis of Lyme borreliosis","volume":"49","author":"Wilske","year":"2007","journal-title":"FEMS Immunol. Med. Microbiol."}],"container-title":["Ticks and Tick-borne Diseases"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877959X18303170?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1877959X18303170?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,1,18]],"date-time":"2021-01-18T04:51:18Z","timestamp":1610945478000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1877959X18303170"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["S1877959X18303170"],"URL":"https:\/\/doi.org\/10.1016\/j.ttbdis.2018.09.011","relation":{},"ISSN":["1877-959X"],"issn-type":[{"value":"1877-959X","type":"print"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Immunoblot reactivity at follow-up in treated patients with Lyme neuroborreliosis and healthy controls","name":"articletitle","label":"Article Title"},{"value":"Ticks and Tick-borne Diseases","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ttbdis.2018.09.011","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Published by Elsevier GmbH.","name":"copyright","label":"Copyright"}]}}