{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,16]],"date-time":"2026-03-16T02:15:12Z","timestamp":1773627312836,"version":"3.50.1"},"reference-count":95,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T00:00:00Z","timestamp":1409529600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"name":"Russian Foundation for Basic Research","award":["13-04-40070-\u041d"],"award-info":[{"award-number":["13-04-40070-\u041d"]}]},{"name":"Russian Foundation for Basic Research","award":["13-04-40071-\u041d"],"award-info":[{"award-number":["13-04-40071-\u041d"]}]},{"name":"Russian Foundation for Basic Research","award":["13-04-40072-\u041d"],"award-info":[{"award-number":["13-04-40072-\u041d"]}]}],"content-domain":{"domain":["tuberculosisjournal.com","mdconsult.com","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Tuberculosis"],"published-print":{"date-parts":[[2014,9]]},"DOI":"10.1016\/j.tube.2014.06.009","type":"journal-article","created":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T06:49:12Z","timestamp":1404283752000},"page":"462-468","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":29,"title":["Latent tuberculosis infection: What we know about its genetic control?"],"prefix":"10.1016","volume":"94","author":[{"given":"Tatiana","family":"Kondratieva","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tatyana","family":"Azhikina","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Boris","family":"Nikonenko","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Arseny","family":"Kaprelyants","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander","family":"Apt","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tube.2014.06.009_bib1","doi-asserted-by":"crossref","first-page":"845","DOI":"10.1038\/nrmicro2236","article-title":"The spectrum of latent tuberculosis: rethinking the biology and intervention strategies","volume":"7","author":"Barry","year":"2009","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.tube.2014.06.009_bib2","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.1084\/jem.20090892","article-title":"Two loci control tuberculin skin test reactivity in an area hyperendemic for tuberculosis","volume":"206","author":"Cobat","year":"2009","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.tube.2014.06.009_bib3","doi-asserted-by":"crossref","first-page":"679","DOI":"10.3201\/eid0807.010482","article-title":"Persistent high incidence of tuberculosis in immigrants in a low-incidence country","volume":"8","author":"Lillebaek","year":"2002","journal-title":"Emerg Infect Dis"},{"key":"10.1016\/j.tube.2014.06.009_bib4","doi-asserted-by":"crossref","first-page":"567","DOI":"10.1016\/j.immuni.2010.09.015","article-title":"Future vaccination strategies against tuberculosis: thinking outside the box","volume":"33","author":"Kaufmann","year":"2010","journal-title":"Immunity"},{"key":"10.1016\/j.tube.2014.06.009_bib5","doi-asserted-by":"crossref","first-page":"e1002607","DOI":"10.1371\/journal.ppat.1002607","article-title":"Vaccines against tuberculosis: where are we and where do we need to go?","volume":"8","author":"Ottenhoff","year":"2012","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.tube.2014.06.009_bib6","doi-asserted-by":"crossref","first-page":"477","DOI":"10.1016\/0962-8479(95)90521-9","article-title":"Mycobacterial dormancy","volume":"76","author":"Gangadharam","year":"1995","journal-title":"Tuber Lung Dis"},{"key":"10.1016\/j.tube.2014.06.009_bib7","doi-asserted-by":"crossref","first-page":"814943","DOI":"10.1155\/2011\/814943","article-title":"Pathogenesis, immunology, and diagnosis of latent Mycobacterium tuberculosis infection","volume":"2011","author":"Ahmad","year":"2011","journal-title":"Clin Dev Immunol"},{"key":"10.1016\/j.tube.2014.06.009_bib8","doi-asserted-by":"crossref","first-page":"80","DOI":"10.1007\/s15010-008-8087-y","article-title":"A\u00a0dynamic reinfection hypothesis of latent tuberculosis infection","volume":"37","author":"Cardona","year":"2009","journal-title":"Infection"},{"key":"10.1016\/j.tube.2014.06.009_bib9","doi-asserted-by":"crossref","first-page":"261","DOI":"10.1002\/path.1906","article-title":"New insights into the function of granulomas in human tuberculosis","volume":"208","author":"Ulrichs","year":"2006","journal-title":"J\u00a0Pathol"},{"key":"10.1016\/j.tube.2014.06.009_bib10","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1146\/annurev.micro.112408.134043","article-title":"Letting sleeping dos lie: does dormancy play a role in tuberculosis?","volume":"64","author":"Chao","year":"2010","journal-title":"Annu Rev Microbiol"},{"key":"10.1016\/j.tube.2014.06.009_bib11","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1038\/nrmicro2453","article-title":"Exit from dormancy in microbial organisms","volume":"8","author":"Dworkin","year":"2010","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.tube.2014.06.009_bib12","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1111\/j.1574-6976.2012.00331.x","article-title":"Mycobacterium tuberculosis: success through dormancy","volume":"36","author":"Gengenbacher","year":"2012","journal-title":"FEMS Microbiol Rev"},{"key":"10.1016\/j.tube.2014.06.009_bib13","doi-asserted-by":"crossref","first-page":"87","DOI":"10.1007\/s15010-009-8450-7","article-title":"Lazy, dynamic or minimally recrudescent? on the elusive nature and location of the mycobacterium responsible for latent tuberculosis","volume":"37","author":"Ehlers","year":"2009","journal-title":"Infection"},{"key":"10.1016\/j.tube.2014.06.009_bib14","doi-asserted-by":"crossref","first-page":"546","DOI":"10.1128\/IAI.73.1.546-551.2005","article-title":"Replication dynamics of Mycobacterium tuberculosis in chronically infected mice","volume":"73","author":"Munoz-Elias","year":"2005","journal-title":"Infect Immun"},{"key":"10.1016\/j.tube.2014.06.009_bib15","doi-asserted-by":"crossref","first-page":"1164","DOI":"10.1016\/j.meegid.2011.02.002","article-title":"How dormant is Mycobacterium tuberculosis during latency? A study integrating genomics and molecular epidemiology","volume":"11","author":"Yang","year":"2011","journal-title":"Infect Genet Evol"},{"key":"10.1016\/j.tube.2014.06.009_bib16","doi-asserted-by":"crossref","first-page":"833","DOI":"10.1046\/j.1365-2958.2003.03474.x","article-title":"Rv3133c\/dosR is a transcription factor that mediates the hypoxic\u00a0response of Mycobacterium tuberculosis","volume":"48","author":"Park","year":"2003","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.tube.2014.06.009_bib17","doi-asserted-by":"crossref","first-page":"7534","DOI":"10.1073\/pnas.121172498","article-title":"Regulation of the Mycobacterium tuberculosis hypoxic response gene encoding alpha -crystallin","volume":"98","author":"Sherman","year":"2001","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.tube.2014.06.009_bib18","doi-asserted-by":"crossref","first-page":"705","DOI":"10.1084\/jem.20030205","article-title":"Inhibition of respiration by nitric oxide induces a Mycobacterium tuberculosis dormancy program","volume":"198","author":"Voskuil","year":"2003","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.tube.2014.06.009_bib19","doi-asserted-by":"crossref","first-page":"e1502","DOI":"10.1371\/journal.pone.0001502","article-title":"The enduring hypoxic response of Mycobacterium tuberculosis","volume":"3","author":"Rustad","year":"2008","journal-title":"PLoS One"},{"key":"10.1016\/j.tube.2014.06.009_bib20","doi-asserted-by":"crossref","first-page":"693","DOI":"10.1084\/jem.20030846","article-title":"Transcriptional adaptation of Mycobacterium tuberculosis within macrophages: insights into the phagosomal environment","volume":"198","author":"Schnappinger","year":"2003","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.tube.2014.06.009_bib21","doi-asserted-by":"crossref","first-page":"647","DOI":"10.1084\/jem.20040646","article-title":"Dormancy phenotype displayed by extracellular Mycobacterium tuberculosis within artificial granulomas in mice","volume":"200","author":"Karakousis","year":"2004","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.tube.2014.06.009_bib22","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1111\/j.1574-695X.2006.00160.x","article-title":"Expression of mycobacterial cell division protein, FtsZ, and dormancy proteins, DevR and Acr, within lung granulomas throughout guinea pig infection","volume":"48","author":"Sharma","year":"2006","journal-title":"FEMS Immunol Med Microbiol"},{"key":"10.1016\/j.tube.2014.06.009_bib23","doi-asserted-by":"crossref","first-page":"9578","DOI":"10.1073\/pnas.95.16.9578","article-title":"The 16-kDa alpha-crystallin (Acr) protein of Mycobacterium tuberculosis is required for growth in macrophages","volume":"95","author":"Yuan","year":"1998","journal-title":"Proc Natl Acad Sci USA"},{"key":"10.1016\/j.tube.2014.06.009_bib24","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.2741\/1291","article-title":"Persistent and dormant tubercle bacilli and latent tuberculosis","volume":"9","author":"Zhang","year":"2004","journal-title":"Front Biosci"},{"key":"10.1016\/j.tube.2014.06.009_bib25","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1128\/JB.01270-13","article-title":"Essentiality of DevR\/DosR interaction with SigA for the dormancy survival program in Mycobacterium tuberculosis","volume":"196","author":"Gautam","year":"2014","journal-title":"J\u00a0Bacteriol"},{"key":"10.1016\/j.tube.2014.06.009_bib26","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1016\/j.cyto.2013.06.310","article-title":"Dormancy associated translation inhibitor (DATIN\/Rv0079) of Mycobacterium tuberculosis interacts with TLR2 and induces proinflammatory cytokine expression","volume":"64","author":"Kumar","year":"2013","journal-title":"Cytokine"},{"key":"10.1016\/j.tube.2014.06.009_bib27","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.1128\/JB.00926-09","article-title":"The Mycobacterium tuberculosis DosR regulon assists in metabolic homeostasis and enables rapid recovery from nonrespiring dormancy","volume":"192","author":"Leistikow","year":"2010","journal-title":"J\u00a0Bacteriol"},{"key":"10.1016\/j.tube.2014.06.009_bib28","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1016\/j.tube.2008.12.003","article-title":"DevR-mediated adaptive response in Mycobacterium tuberculosis H37Ra: links to asparagine metabolism","volume":"89","author":"Malhotra","year":"2009","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.tube.2014.06.009_bib29","doi-asserted-by":"crossref","first-page":"e35935","DOI":"10.1371\/journal.pone.0035935","article-title":"Mycobacterium tuberculosis growth following aerobic expression of the DosR regulon","volume":"7","author":"Minch","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.tube.2014.06.009_bib30","doi-asserted-by":"crossref","first-page":"513","DOI":"10.2217\/fmb.12.14","article-title":"How Mycobacterium tuberculosis goes to sleep: the dormancy survival regulator DosR a decade later","volume":"7","author":"Boon","year":"2012","journal-title":"Future Microbiol"},{"key":"10.1016\/j.tube.2014.06.009_bib31","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1186\/1471-2334-7-84","article-title":"Identification of gene targets against dormant phase Mycobacterium tuberculosis infections","volume":"7","author":"Murphy","year":"2007","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.tube.2014.06.009_bib32","doi-asserted-by":"crossref","first-page":"625","DOI":"10.1016\/j.tube.2013.09.002","article-title":"Cyclic di-GMP mediates Mycobacterium tuberculosis dormancy and pathogenecity","volume":"93","author":"Hong","year":"2013","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.tube.2014.06.009_bib33","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1016\/j.tim.2005.06.008","article-title":"The PIN-domain toxin-antitoxin array in mycobacteria","volume":"13","author":"Arcus","year":"2005","journal-title":"Trends Microbiol"},{"key":"10.1016\/j.tube.2014.06.009_bib34","doi-asserted-by":"crossref","first-page":"69","DOI":"10.1111\/1574-6968.12380","article-title":"Toxin-antitoxin vapBC locus participates in formation of the dormant state in Mycobacterium smegmatis","volume":"352","author":"Demidenok","year":"2014","journal-title":"FEMS Microbiol Lett"},{"key":"10.1016\/j.tube.2014.06.009_bib35","doi-asserted-by":"crossref","first-page":"101","DOI":"10.4161\/rna.27949","article-title":"23S rRNA as an a-Maz-ing new bacterial toxin target","volume":"11","author":"Schifano","year":"2014","journal-title":"RNA Biol"},{"key":"10.1016\/j.tube.2014.06.009_bib36","doi-asserted-by":"crossref","first-page":"4195","DOI":"10.1128\/IAI.69.7.4195-4201.2001","article-title":"Tuberculosis: latency and reactivation","volume":"69","author":"Flynn","year":"2001","journal-title":"Infect Immun"},{"key":"10.1016\/j.tube.2014.06.009_bib37","doi-asserted-by":"crossref","first-page":"e58378","DOI":"10.1371\/journal.pone.0058378","article-title":"Transcription of genes involved in sulfolipid and polyacyltrehalose biosynthesis of Mycobacterium tuberculosis in experimental latent tuberculosis infection","volume":"8","author":"Rodr\u00edguez","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.tube.2014.06.009_bib38","first-page":"83","volume":"vol. 1","author":"Mukamolova","year":"2008"},{"key":"10.1016\/j.tube.2014.06.009_bib39","first-page":"3","article-title":"Dormant form of Mycobacterium tuberculosis","volume":"79","author":"Shleeva","year":"2010","journal-title":"Mikrobiologiia"},{"key":"10.1016\/j.tube.2014.06.009_bib40","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.tube.2010.12.006","article-title":"Dormant ovoid cells of Mycobacterium tuberculosis are formed in response to gradual external acidification","volume":"91","author":"Shleeva","year":"2011","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.tube.2014.06.009_bib41","doi-asserted-by":"crossref","first-page":"73","DOI":"10.32607\/20758251-2009-1-2-73-77","article-title":"M.\u00a0tuberculosis gene expression during transition to the \u201cNon-Culturable\u201d state","volume":"1","author":"Salina","year":"2009","journal-title":"Acta Naturae"},{"key":"10.1016\/j.tube.2014.06.009_bib42","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.00100-11","article-title":"Characterization and transcriptome analysis of Mycobacterium tuberculosis persisters","volume":"2","author":"Keren","year":"2011","journal-title":"MBio"},{"key":"10.1016\/j.tube.2014.06.009_bib43","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1186\/1471-2334-7-146","article-title":"The role of resuscitation promoting factors in pathogenesis and reactivation of Mycobacterium tuberculosis during intra-peritoneal infection in mice","volume":"7","author":"Biketov","year":"2007","journal-title":"BMC Infect Dis"},{"key":"10.1016\/j.tube.2014.06.009_bib44","doi-asserted-by":"crossref","first-page":"3038","DOI":"10.1128\/IAI.73.5.3038-3043.2005","article-title":"Mutants of Mycobacterium tuberculosis lacking three of the five rpf-like genes are defective for growth in\u00a0vivo and for resuscitation in\u00a0vitro","volume":"73","author":"Downing","year":"2005","journal-title":"Infect Immun"},{"key":"10.1016\/j.tube.2014.06.009_bib45","doi-asserted-by":"crossref","DOI":"10.1016\/j.ddmec.2010.08.003","article-title":"Resuscitation promoting factors in bacterial population dynamics during TB infection","volume":"7","author":"Kana","year":"2010","journal-title":"Drug Discov Today Dis Mech"},{"key":"10.1016\/j.tube.2014.06.009_bib46","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.tube.2008.08.004","article-title":"Tuberculosis genes expressed during persistence and reactivation in the resistant rabbit model","volume":"89","author":"Kesavan","year":"2009","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.tube.2014.06.009_bib47","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1038\/nsmb905","article-title":"The structure of a resuscitation-promoting factor domain from Mycobacterium tuberculosis shows homology to lysozymes","volume":"12","author":"Cohen-Gonsaud","year":"2005","journal-title":"Nat Struct Mol Biol"},{"key":"10.1016\/j.tube.2014.06.009_bib48","doi-asserted-by":"crossref","first-page":"e82914","DOI":"10.1371\/journal.pone.0082914","article-title":"Cyclic amp-dependent resuscitation of dormant mycobacteria by exogenous free fatty acids","volume":"8","author":"Shleeva","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.tube.2014.06.009_bib49","doi-asserted-by":"crossref","first-page":"585","DOI":"10.1038\/nmeth0708-585","article-title":"The beginning of the end for microarrays?","volume":"5","author":"Shendure","year":"2008","journal-title":"Nat Methods"},{"key":"10.1016\/j.tube.2014.06.009_bib50","first-page":"366","article-title":"DNA sequencing - spanning the generations","volume":"30","author":"McGinn","year":"2013","journal-title":"N\u00a0Biotechnol"},{"key":"10.1016\/j.tube.2014.06.009_bib51","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1038\/nrg2626","article-title":"Sequencing technologies - the next generation","volume":"11","author":"Metzker","year":"2010","journal-title":"Nat Rev Genet"},{"key":"10.1016\/j.tube.2014.06.009_bib52","doi-asserted-by":"crossref","first-page":"231","DOI":"10.1517\/17460441.2012.660145","article-title":"Third-generation sequencing techniques and applications to drug discovery","volume":"7","author":"Ozsolak","year":"2012","journal-title":"Expert Opin Drug Discov"},{"key":"10.1016\/j.tube.2014.06.009_bib53","doi-asserted-by":"crossref","first-page":"427","DOI":"10.4161\/rna.20105","article-title":"Non-coding RNA and its potential role in Mycobacterium tuberculosis pathogenesis","volume":"9","author":"Arnvig","year":"2012","journal-title":"RNA Biol"},{"key":"10.1016\/j.tube.2014.06.009_bib54","doi-asserted-by":"crossref","first-page":"e1002342","DOI":"10.1371\/journal.ppat.1002342","article-title":"Sequence-based analysis uncovers an abundance of non-coding RNA in the total transcriptome of Mycobacterium tuberculosis","volume":"7","author":"Arnvig","year":"2011","journal-title":"PLoS Pathog"},{"key":"10.1016\/j.tube.2014.06.009_bib55","doi-asserted-by":"crossref","first-page":"397","DOI":"10.1111\/j.1365-2958.2009.06777.x","article-title":"Identification of small RNAs in Mycobacterium tuberculosis","volume":"73","author":"Arnvig","year":"2009","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.tube.2014.06.009_bib56","doi-asserted-by":"crossref","first-page":"e51950","DOI":"10.1371\/journal.pone.0051950","article-title":"Genome-wide discovery of small RNAs in Mycobacterium tuberculosis","volume":"7","author":"Miotto","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.tube.2014.06.009_bib57","doi-asserted-by":"crossref","first-page":"e32723","DOI":"10.1371\/journal.pone.0032723","article-title":"A\u00a0genome-wide identification analysis of small regulatory RNAs in Mycobacterium tuberculosis by RNA-Seq and conservation analysis","volume":"7","author":"Pellin","year":"2012","journal-title":"PLoS One"},{"key":"10.1016\/j.tube.2014.06.009_bib58","doi-asserted-by":"crossref","first-page":"961","DOI":"10.1093\/nar\/gks1260","article-title":"High-resolution transcriptome and genome-wide dynamics of RNA polymerase and NusA in Mycobacterium tuberculosis","volume":"41","author":"Uplekar","year":"2013","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.tube.2014.06.009_bib59","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1111\/j.1574-6976.2011.00302.x","article-title":"Pathogenesis in tuberculosis: transcriptomic approaches to unraveling virulence mechanisms and finding new drug targets","volume":"36","author":"Mukhopadhyay","year":"2012","journal-title":"FEMS Microbiol Rev"},{"key":"10.1016\/j.tube.2014.06.009_bib60","doi-asserted-by":"crossref","first-page":"139","DOI":"10.2144\/000113350","article-title":"A\u00a0new technique for obtaining whole pathogen transcriptomes from infected host tissues","volume":"48","author":"Azhikina","year":"2010","journal-title":"Biotechniques"},{"key":"10.1016\/j.tube.2014.06.009_bib61","doi-asserted-by":"crossref","first-page":"e74209","DOI":"10.1371\/journal.pone.0074209","article-title":"RNA-seq analysis of Mycobacterium avium non-coding transcriptome","volume":"8","author":"Ignatov","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.tube.2014.06.009_bib62","doi-asserted-by":"crossref","first-page":"62","DOI":"10.32607\/20758251-2013-5-2-62-69","article-title":"Mycobacterium tuberculosis transcriptome profiling in mice with genetically different susceptibility to tuberculosis","volume":"5","author":"Skvortsov","year":"2013","journal-title":"Acta Naturae"},{"key":"10.1016\/j.tube.2014.06.009_bib63","doi-asserted-by":"crossref","first-page":"615","DOI":"10.1016\/j.cell.2009.01.043","article-title":"Regulatory RNAs in bacteria","volume":"136","author":"Waters","year":"2009","journal-title":"Cell"},{"key":"10.1016\/j.tube.2014.06.009_bib64","doi-asserted-by":"crossref","first-page":"6179","DOI":"10.1128\/JB.186.18.6179-6185.2004","article-title":"The small noncoding DsrA RNA is an acid resistance regulator in Escherichia coli","volume":"186","author":"Lease","year":"2004","journal-title":"J\u00a0Bacteriol"},{"key":"10.1016\/j.tube.2014.06.009_bib65","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.mib.2007.03.004","article-title":"Small noncoding RNAs controlling pathogenesis","volume":"10","author":"Toledo-Arana","year":"2007","journal-title":"Curr Opin Microbiol"},{"key":"10.1016\/j.tube.2014.06.009_bib66","doi-asserted-by":"crossref","first-page":"4067","DOI":"10.1093\/nar\/gkq101","article-title":"Multiple small RNAs identified in Mycobacterium bovis BCG are also expressed in Mycobacterium tuberculosis and Mycobacterium smegmatis","volume":"38","author":"DiChiara","year":"2010","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.tube.2014.06.009_bib67","doi-asserted-by":"crossref","first-page":"e75828","DOI":"10.1371\/journal.pone.0075828","article-title":"Revealing of Mycobacterium marinum Transcriptome by RNA-seq","volume":"8","author":"Wang","year":"2013","journal-title":"PLoS One"},{"key":"10.1016\/j.tube.2014.06.009_bib68","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1134\/S1068162012040085","article-title":"Novel small RNAs from Mycobacterium avium","volume":"38","author":"Ignatov","year":"2012","journal-title":"Russ J Bioorg Chem"},{"key":"10.1016\/j.tube.2014.06.009_bib69","doi-asserted-by":"crossref","first-page":"109","DOI":"10.1111\/j.1365-2567.2011.03472.x","article-title":"Are mouse models of human mycobacterial diseases relevant? Genetics says: 'yes!'","volume":"134","author":"Apt","year":"2011","journal-title":"Immunology"},{"key":"10.1016\/j.tube.2014.06.009_bib70","first-page":"880","article-title":"Tuberculosis: pathogenesis, immune responses and genetics of the host","volume":"42","author":"Apt","year":"2008","journal-title":"Mol Biol Mosk"},{"key":"10.1016\/j.tube.2014.06.009_bib71","doi-asserted-by":"crossref","first-page":"39","DOI":"10.1038\/nrmicro1538","article-title":"Who puts the tubercle in tuberculosis?","volume":"5","author":"Russell","year":"2007","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.tube.2014.06.009_bib72","doi-asserted-by":"crossref","first-page":"599","DOI":"10.1146\/annurev.immunol.22.012703.104635","article-title":"Immunity to tuberculosis","volume":"22","author":"North","year":"2004","journal-title":"Annu Rev Immunol"},{"key":"10.1016\/j.tube.2014.06.009_bib73","doi-asserted-by":"crossref","first-page":"908","DOI":"10.1007\/BF02111491","article-title":"Dormancy of Mycobacterium tuberculosis and latency of disease","volume":"13","author":"Wayne","year":"1994","journal-title":"Eur J Clin Microbiol Infect Dis"},{"key":"10.1016\/j.tube.2014.06.009_bib74","doi-asserted-by":"crossref","first-page":"270","DOI":"10.1046\/j.1365-2567.1998.00419.x","article-title":"Resistance ranking of some common inbred mouse strains to Mycobacterium tuberculosis and relationship to major histocompatibility complex haplotype and Nramp1 genotype","volume":"93","author":"Medina","year":"1998","journal-title":"Immunology"},{"key":"10.1016\/j.tube.2014.06.009_bib75","doi-asserted-by":"crossref","first-page":"57","DOI":"10.1016\/S0962-8479(97)90016-2","article-title":"Progression of chronic pulmonary tuberculosis in mice aerogenically infected with virulent Mycobacterium tuberculosis","volume":"78","author":"Rhoades","year":"1997","journal-title":"Tuber Lung Dis"},{"key":"10.1016\/j.tube.2014.06.009_bib76","doi-asserted-by":"crossref","first-page":"445","DOI":"10.1084\/jem.123.3.445","article-title":"Microbial persistence. I. The capacity of tubercle bacilli to survive sterilization in mouse tissues","volume":"123","author":"McCune","year":"1966","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.tube.2014.06.009_bib77","doi-asserted-by":"crossref","first-page":"469","DOI":"10.1084\/jem.123.3.469","article-title":"Microbial persistence. II. Characteristics of the sterile state of tubercle bacilli","volume":"123","author":"McCune","year":"1966","journal-title":"J\u00a0Exp Med"},{"key":"10.1016\/j.tube.2014.06.009_bib78","doi-asserted-by":"crossref","first-page":"555","DOI":"10.1016\/0962-8479(95)90534-0","article-title":"The bacterial DNA content of mouse organs in the Cornell model of dormant tuberculosis","volume":"76","author":"de Wit","year":"1995","journal-title":"Tuber Lung Dis"},{"key":"10.1016\/j.tube.2014.06.009_bib79","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1016\/0962-8479(94)90105-8","article-title":"Effect of vaccines in a murine model of dormant tuberculosis","volume":"75","author":"Dhillon","year":"1994","journal-title":"Tuber Lung Dis"},{"key":"10.1016\/j.tube.2014.06.009_bib80","doi-asserted-by":"crossref","first-page":"4531","DOI":"10.1128\/IAI.67.9.4531-4538.1999","article-title":"Reactivation of latent tuberculosis: variations on the Cornell murine model","volume":"67","author":"Scanga","year":"1999","journal-title":"Infect Immun"},{"key":"10.1016\/j.tube.2014.06.009_bib81","doi-asserted-by":"crossref","first-page":"e10515","DOI":"10.1371\/journal.pone.0010515","article-title":"Host genetics in granuloma formation: human-like lung pathology in mice with reciprocal genetic susceptibility to M. tuberculosis and M. avium","volume":"5","author":"Kondratieva","year":"2010","journal-title":"PLoS One"},{"key":"10.1016\/j.tube.2014.06.009_bib82","series-title":"Handbook of tuberculosis","article-title":"Genetic control of host susceptibility to tuberculosis","author":"Schurr","year":"2008"},{"key":"10.1016\/j.tube.2014.06.009_bib83","first-page":"458","article-title":"Relapses after stopping chemotherapy for experimental tuberculosis in genetically\u00a0resistant and susceptible strains of mice","volume":"76","author":"Lecoeur","year":"1989","journal-title":"Clin Exp Immunol"},{"key":"10.1016\/j.tube.2014.06.009_bib84","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1016\/j.tube.2004.09.014","article-title":"Direct comparison of low-dose and Cornell-like models of chronic and reactivation tuberculosis in genetically susceptible I\/St and resistant B6 mice","volume":"85","author":"Radaeva","year":"2005","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.tube.2014.06.009_bib85","doi-asserted-by":"crossref","first-page":"576","DOI":"10.1016\/j.tube.2008.05.003","article-title":"A\u00a0human-like TB in genetically susceptible mice followed by the true dormancy in a Cornell-like model","volume":"88","author":"Radaeva","year":"2008","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.tube.2014.06.009_bib86","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/j.1600-065X.2010.00984.x","article-title":"Mycobacterium tuberculosis and the intimate discourse of a chronic infection","volume":"240","author":"Russell","year":"2011","journal-title":"Immunol Rev"},{"key":"10.1016\/j.tube.2014.06.009_bib87","doi-asserted-by":"crossref","first-page":"219","DOI":"10.1016\/j.tube.2011.01.005","article-title":"Mycobacterium tuberculosis attenuated by multiple deletions of rpf genes effectively protects mice against TB infection","volume":"91","author":"Kondratieva","year":"2011","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.tube.2014.06.009_bib88","doi-asserted-by":"crossref","first-page":"553","DOI":"10.1164\/rccm.200807-1152OC","article-title":"Sterilizing activity of R207910 (TMC207)-containing regimens in the murine model of tuberculosis","volume":"180","author":"Ibrahim","year":"2009","journal-title":"Am J Respir Crit Care Med"},{"key":"10.1016\/j.tube.2014.06.009_bib89","doi-asserted-by":"crossref","first-page":"2621","DOI":"10.1128\/AAC.00451-06","article-title":"Combination chemotherapy with the nitroimidazopyran PA-824 and first-line drugs in a murine model of tuberculosis","volume":"50","author":"Nuermberger","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.tube.2014.06.009_bib90","doi-asserted-by":"crossref","first-page":"285","DOI":"10.1016\/j.tube.2013.02.010","article-title":"Drug testing in mouse models of tuberculosis and nontuberculous mycobacterial infections","volume":"93","author":"Nikonenko","year":"2013","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.tube.2014.06.009_bib91","doi-asserted-by":"crossref","first-page":"3181","DOI":"10.1128\/AAC.00217-12","article-title":"Evaluation of a mouse model of necrotic granuloma formation using C3HeB\/FeJ mice for testing of drugs against Mycobacterium tuberculosis","volume":"56","author":"Driver","year":"2012","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.tube.2014.06.009_bib92","doi-asserted-by":"crossref","first-page":"3664","DOI":"10.1128\/AAC.00686-08","article-title":"Enhanced bactericidal activity of rifampin and\/or pyrazinamide when combined with PA-824 in a murine model of tuberculosis","volume":"52","author":"Tasneen","year":"2008","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.tube.2014.06.009_bib93","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/j.tube.2008.09.001","article-title":"Prevention of the post-chemotherapy relapse of tuberculous infection\u00a0by\u00a0combined immunotherapy","volume":"89","author":"Buccheri","year":"2009","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.tube.2014.06.009_bib94","doi-asserted-by":"crossref","first-page":"823","DOI":"10.2217\/fmb.12.56","article-title":"Discovery and development of SQ109: a new antitubercular drug with a novel mechanism of action","volume":"7","author":"Sacksteder","year":"2012","journal-title":"Future Microbiol"},{"key":"10.1016\/j.tube.2014.06.009_bib95","doi-asserted-by":"crossref","first-page":"3114","DOI":"10.1128\/AAC.00384-12","article-title":"Sterilizing activities of novel combinations lacking first- and second-line drugs in a murine model of tuberculosis","volume":"56","author":"Williams","year":"2012","journal-title":"Antimicrob Agents Chemother"}],"container-title":["Tuberculosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472979214204434?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472979214204434?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,8,21]],"date-time":"2020-08-21T18:09:38Z","timestamp":1598033378000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1472979214204434"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":95,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2014,9]]}},"alternative-id":["S1472979214204434"],"URL":"https:\/\/doi.org\/10.1016\/j.tube.2014.06.009","relation":{},"ISSN":["1472-9792"],"issn-type":[{"value":"1472-9792","type":"print"}],"subject":[],"published":{"date-parts":[[2014,9]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Latent tuberculosis infection: What we know about its genetic control?","name":"articletitle","label":"Article Title"},{"value":"Tuberculosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tube.2014.06.009","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2014 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}