{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,2]],"date-time":"2026-03-02T04:15:43Z","timestamp":1772424943366,"version":"3.50.1"},"reference-count":7,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2016,8,1]],"date-time":"2016-08-01T00:00:00Z","timestamp":1470009600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2016,6,15]],"date-time":"2016-06-15T00:00:00Z","timestamp":1465948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["tuberculosisjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Tuberculosis"],"published-print":{"date-parts":[[2016,8]]},"DOI":"10.1016\/j.tube.2016.05.012","type":"journal-article","created":{"date-parts":[[2016,6,18]],"date-time":"2016-06-18T16:40:36Z","timestamp":1466268036000},"page":"S12-S15","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"special_numbering":"S1","title":["Novel approaches to preclinical research and TB vaccine development"],"prefix":"10.1016","volume":"99","author":[{"given":"Kenneth Barry","family":"Walker","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yan","family":"Guo","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Johanna","family":"Poecheim","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kamalakannan","family":"Velmurugan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lewis K.","family":"Schrager","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tube.2016.05.012_bib1","doi-asserted-by":"crossref","first-page":"2400","DOI":"10.1128\/IAI.01599-13","article-title":"Early Changes by 18Fluorodeoxyglucose positron emission tomography coregistered with computed tomography predict outcome after Mycobacterium tuberculosis infection in cynomolgus macaques","volume":"82","author":"Coleman","year":"2014","journal-title":"Infect Immun"},{"key":"10.1016\/j.tube.2016.05.012_bib2","doi-asserted-by":"crossref","first-page":"422","DOI":"10.1016\/j.tube.2012.05.008","article-title":"Dissecting memory T cell responses to TB: concerns using adoptive transfer into immunodeficient mice","volume":"92","author":"Ancelet","year":"2012","journal-title":"Tuberc (Edinb)"},{"key":"10.1016\/j.tube.2016.05.012_bib3","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tube.2015.10.004","article-title":"Ultra low dose aerosol challenge with Mycobacterium tuberculosis leads to divergent outcomes in rhesus and cynomolgus macaques","volume":"96","author":"Sharpe","year":"2016","journal-title":"Tuberc (Edinb)"},{"key":"10.1016\/j.tube.2016.05.012_bib4","doi-asserted-by":"crossref","first-page":"10963","DOI":"10.1128\/JVI.01284-09","article-title":"Lentiviral vector-based prime\/boost vaccination against AIDS: pilot study shows protection against Simian immunodeficiency virus SIVmac251 challenge in macaques","volume":"83","author":"Beignon","year":"2009","journal-title":"J\u00a0Virol"},{"key":"10.1016\/j.tube.2016.05.012_bib5","doi-asserted-by":"crossref","first-page":"780","DOI":"10.1002\/eji.201444954","article-title":"Epitope-specific CD4+, but not CD8+, T-cell responses induced by recombinant influenza A viruses protect against Mycobacterium tuberculosis infection","volume":"45","author":"Fl\u00f3rido","year":"2015","journal-title":"Eur J Immunol"},{"key":"10.1016\/j.tube.2016.05.012_bib6","doi-asserted-by":"crossref","first-page":"5633","DOI":"10.1016\/j.vaccine.2015.08.084","article-title":"Protection by novel vaccine candidates, Mycobacterium tuberculosis \u0394mosR and \u0394echA7, against challenge with a Mycobacterium tuberculosis Beijing strain","volume":"33","author":"Marcus","year":"2015","journal-title":"Vaccine"},{"key":"10.1016\/j.tube.2016.05.012_bib7","doi-asserted-by":"crossref","first-page":"5941","DOI":"10.1128\/JB.00778-09","article-title":"mosR, a novel transcriptional regulator of hypoxia and virulence in Mycobacterium tuberculosis","volume":"191","author":"Abomoelak","year":"2009","journal-title":"J\u00a0Bacteriol"}],"container-title":["Tuberculosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472979216301901?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472979216301901?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2018,9,11]],"date-time":"2018-09-11T00:28:46Z","timestamp":1536625726000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1472979216301901"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8]]},"references-count":7,"alternative-id":["S1472979216301901"],"URL":"https:\/\/doi.org\/10.1016\/j.tube.2016.05.012","relation":{},"ISSN":["1472-9792"],"issn-type":[{"value":"1472-9792","type":"print"}],"subject":[],"published":{"date-parts":[[2016,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Novel approaches to preclinical research and TB vaccine development","name":"articletitle","label":"Article Title"},{"value":"Tuberculosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tube.2016.05.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2016 The Authors. Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}