{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,2]],"date-time":"2026-06-02T20:20:03Z","timestamp":1780431603302,"version":"3.54.1"},"reference-count":39,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2017,7,1]],"date-time":"2017-07-01T00:00:00Z","timestamp":1498867200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["tuberculosisjournal.com","clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.com.au","clinicalkey.fr","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Tuberculosis"],"published-print":{"date-parts":[[2017,7]]},"DOI":"10.1016\/j.tube.2017.04.004","type":"journal-article","created":{"date-parts":[[2017,4,19]],"date-time":"2017-04-19T21:46:20Z","timestamp":1492638380000},"page":"73-79","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":12,"special_numbering":"C","title":["miR-30c is specifically repressed in patients with active pulmonary tuberculosis"],"prefix":"10.1016","volume":"105","author":[{"given":"Silvana V.","family":"Spinelli","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3457-4139","authenticated-orcid":false,"given":"Roc\u00edo del V.","family":"Fern\u00e1ndez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciana","family":"Zoff","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bettina","family":"Bongiovanni","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ariana","family":"D\u00edaz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luciano","family":"D'Attilio","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Natalia","family":"Santucci","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8514-5158","authenticated-orcid":false,"given":"Tom\u00e1s","family":"Alvarez","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marcela M.","family":"Marchesini","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cristina","family":"Bogue","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maria L.","family":"Bay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Oscar A.","family":"Bottasso","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tube.2017.04.004_bib1","series-title":"W.H.O., Global tuberculosis report. 2013","author":"(WHO)","year":"2013"},{"issue":"1","key":"10.1016\/j.tube.2017.04.004_bib2","doi-asserted-by":"crossref","first-page":"235","DOI":"10.1111\/j.1600-065X.2010.00994.x","article-title":"For better or for worse: the immune response against Mycobacterium tuberculosis balances pathology and protection","volume":"240","author":"Dorhoi","year":"2011","journal-title":"Immunol Rev"},{"key":"10.1016\/j.tube.2017.04.004_bib3","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1016\/j.clim.2015.11.008","article-title":"Transcriptional profiles discriminate patients with pulmonary tuberculosis from non-tuberculous individuals depending on the presence of non-insulin diabetes mellitus","volume":"162","author":"Serrano","year":"2016","journal-title":"Clin Immunol"},{"issue":"2","key":"10.1016\/j.tube.2017.04.004_bib4","doi-asserted-by":"crossref","first-page":"234","DOI":"10.1046\/j.1365-2567.1998.00601.x","article-title":"The effects of androstenediol and dehydroepiandrosterone on the course and cytokine profile of tuberculosis in BALB\/c mice","volume":"95","author":"Hernandez-Pando","year":"1998","journal-title":"Immunology"},{"key":"10.1016\/j.tube.2017.04.004_bib5","doi-asserted-by":"crossref","first-page":"77","DOI":"10.1016\/j.mcn.2012.11.002","article-title":"Adverse neuro-immune-endocrine interactions in patients with active tuberculosis","volume":"53","author":"Bottasso","year":"2013","journal-title":"Mol Cell Neurosci"},{"issue":"5","key":"10.1016\/j.tube.2017.04.004_bib6","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1016\/j.jaci.2013.09.007","article-title":"The biology of the glucocorticoid receptor: new signaling mechanisms in health and disease","volume":"132","author":"Oakley","year":"2013","journal-title":"J\u00a0Allergy Clin Immunol"},{"issue":"1\u20132","key":"10.1016\/j.tube.2017.04.004_bib7","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.cytogfr.2007.01.011","article-title":"Cytokines and the immune-neuroendocrine network: What did we learn from infection and autoimmunity?","volume":"18","author":"Correa","year":"2007","journal-title":"Cytokine Growth Factor Rev"},{"issue":"2","key":"10.1016\/j.tube.2017.04.004_bib8","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1016\/j.bbi.2006.06.005","article-title":"Endocrine and cytokine responses in humans with pulmonary tuberculosis","volume":"21","author":"Rey","year":"2007","journal-title":"Brain Behav Immun"},{"issue":"1","key":"10.1016\/j.tube.2017.04.004_bib9","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1111\/j.1476-5381.2010.01199.x","article-title":"Glucocorticosteroids: current and future directions","volume":"163","author":"Barnes","year":"2011","journal-title":"Br J Pharmacol"},{"issue":"10","key":"10.1016\/j.tube.2017.04.004_bib10","doi-asserted-by":"crossref","first-page":"2745","DOI":"10.1097\/CCM.0b013e31825b8ebc","article-title":"Corticosteroid resistance in sepsis is influenced by microRNA-124\u2013induced downregulation of glucocorticoid receptor-alpha","volume":"40","author":"Ledderose","year":"2012","journal-title":"Crit Care Med"},{"issue":"4","key":"10.1016\/j.tube.2017.04.004_bib11","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1038\/leu.2011.273","article-title":"An oncogenic role of miR-142-3p in human T-cell acute lymphoblastic leukemia (T-ALL) by targeting glucocorticoid receptor-alpha and cAMP\/PKA pathways","volume":"26","author":"Lv","year":"2012","journal-title":"Leukemia"},{"issue":"2","key":"10.1016\/j.tube.2017.04.004_bib12","doi-asserted-by":"crossref","first-page":"281","DOI":"10.1016\/S0092-8674(04)00045-5","article-title":"MicroRNAs: genomics, biogenesis, mechanism, and function","volume":"116","author":"Bartel","year":"2004","journal-title":"Cell"},{"issue":"5740","key":"10.1016\/j.tube.2017.04.004_bib13","doi-asserted-by":"crossref","first-page":"1519","DOI":"10.1126\/science.1111444","article-title":"Ribo-gnome: the big world of small RNAs","volume":"309","author":"Zamore","year":"2005","journal-title":"Science"},{"issue":"3","key":"10.1016\/j.tube.2017.04.004_bib14","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/j.molimm.2012.08.008","article-title":"Altered microRNA expression levels in mononuclear cells of patients with pulmonary and pleural tuberculosis and their relation with components of the immune response","volume":"53","author":"Spinelli","year":"2013","journal-title":"Mol Immunol"},{"issue":"6","key":"10.1016\/j.tube.2017.04.004_bib15","doi-asserted-by":"crossref","first-page":"596","DOI":"10.1016\/j.tube.2013.08.004","article-title":"The roles of microRNAs on tuberculosis infection: meaning or myth?","volume":"93","author":"Harapan","year":"2013","journal-title":"Tuberculosis (Edinb)"},{"issue":"4","key":"10.1016\/j.tube.2017.04.004_bib16","doi-asserted-by":"crossref","first-page":"1114","DOI":"10.4049\/jimmunol.142.4.1114","article-title":"Compartmentalization of a CD4+ T lymphocyte subpopulation in tuberculous pleuritis","volume":"142","author":"Barnes","year":"1989","journal-title":"J\u00a0Immunol"},{"issue":"5","key":"10.1016\/j.tube.2017.04.004_bib17","first-page":"616","article-title":"Primary serofibrinous pleural effusion in military personnel","volume":"71","author":"Roper","year":"1955","journal-title":"Am Rev Tuberc"},{"key":"10.1016\/j.tube.2017.04.004_bib18","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1007\/978-1-4939-1062-5_25","article-title":"miRWalk database for miRNA-target interactions","volume":"1182","author":"Dweep","year":"2014","journal-title":"Methods Mol Biol"},{"issue":"1","key":"10.1016\/j.tube.2017.04.004_bib19","doi-asserted-by":"crossref","first-page":"92","DOI":"10.1101\/gr.082701.108","article-title":"Most mammalian mRNAs are conserved targets of microRNAs","volume":"19","author":"Friedman","year":"2009","journal-title":"Genome Res"},{"issue":"4","key":"10.1016\/j.tube.2017.04.004_bib20","doi-asserted-by":"crossref","first-page":"507","DOI":"10.7326\/0003-4819-77-4-507","article-title":"Pleural effusions: the diagnostic separation of transudates and exudates","volume":"77","author":"Light","year":"1972","journal-title":"Ann Intern Med"},{"issue":"20","key":"10.1016\/j.tube.2017.04.004_bib21","doi-asserted-by":"crossref","first-page":"e179","DOI":"10.1093\/nar\/gni178","article-title":"Real-time quantification of microRNAs by stem-loop RT-PCR","volume":"33","author":"Chen","year":"2005","journal-title":"Nucleic Acids Res"},{"issue":"2","key":"10.1016\/j.tube.2017.04.004_bib22","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1016\/0039-128X(91)90124-E","article-title":"Autoregulation of glucocorticoid receptor gene expression","volume":"56","author":"Burnstein","year":"1991","journal-title":"Steroids"},{"issue":"6","key":"10.1016\/j.tube.2017.04.004_bib23","doi-asserted-by":"crossref","first-page":"L998","DOI":"10.1152\/ajplung.00459.2007","article-title":"Modulation of glucocorticoid receptor expression, inflammation, and cell apoptosis in septic guinea pig lungs using methylprednisolone","volume":"295","author":"Kamiyama","year":"2008","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"issue":"6","key":"10.1016\/j.tube.2017.04.004_bib24","doi-asserted-by":"crossref","first-page":"635","DOI":"10.1016\/j.tube.2013.07.008","article-title":"Levels of inflammatory cytokines, adrenal steroids, and mRNA for GRalpha, GRbeta and 11betaHSD1 in TB pleurisy","volume":"93","author":"D'Attilio","year":"2013","journal-title":"Tuberculosis (Edinb)"},{"key":"10.1016\/j.tube.2017.04.004_bib25","doi-asserted-by":"crossref","first-page":"10","DOI":"10.1111\/j.1749-6632.2012.06643.x","article-title":"Changes in the immune and endocrine responses of patients with pulmonary tuberculosis undergoing specific treatment","volume":"1262","author":"Bongiovanni","year":"2012","journal-title":"Ann N Y Acad Sci"},{"issue":"4","key":"10.1016\/j.tube.2017.04.004_bib26","doi-asserted-by":"crossref","first-page":"6043","DOI":"10.3892\/mmr.2015.4226","article-title":"Inhibition of microRNA-30a prevents puromycin aminonucleoside-induced podocytic apoptosis by upregulating the glucocorticoid receptor alpha","volume":"12","author":"Xie","year":"2015","journal-title":"Mol Med Rep"},{"key":"10.1016\/j.tube.2017.04.004_bib27","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1016\/j.meegid.2016.09.023","article-title":"MicroRNAs play big roles in modulating macrophages response toward mycobacteria infection","volume":"45","author":"Abdalla","year":"2016","journal-title":"Infect Genet Evol"},{"issue":"8","key":"10.1016\/j.tube.2017.04.004_bib28","doi-asserted-by":"crossref","first-page":"839","DOI":"10.1038\/ni.f.209","article-title":"MicroRNAs: new regulators of immune cell development and function","volume":"9","author":"Baltimore","year":"2008","journal-title":"Nat Immunol"},{"issue":"7","key":"10.1016\/j.tube.2017.04.004_bib29","doi-asserted-by":"crossref","first-page":"343","DOI":"10.1016\/j.it.2008.04.004","article-title":"microRNAs and the immune response","volume":"29","author":"Lindsay","year":"2008","journal-title":"Trends Immunol"},{"issue":"15","key":"10.1016\/j.tube.2017.04.004_bib30","doi-asserted-by":"crossref","first-page":"3978","DOI":"10.3748\/wjg.v22.i15.3978","article-title":"Mir-30d increases intracellular survival of Helicobacter pylori through inhibition of autophagy pathway","volume":"22","author":"Yang","year":"2016","journal-title":"World J Gastroenterol"},{"issue":"5","key":"10.1016\/j.tube.2017.04.004_bib31","doi-asserted-by":"crossref","first-page":"2272","DOI":"10.4049\/jimmunol.1502006","article-title":"MicroRNA-30c Modulates Type I IFN Responses To Facilitate Porcine Reproductive and Respiratory Syndrome Virus Infection by Targeting JAK1","volume":"196","author":"Zhang","year":"2016","journal-title":"J\u00a0Immunol"},{"issue":"9","key":"10.1016\/j.tube.2017.04.004_bib32","first-page":"1761","article-title":"Extrapulmonary tuberculosis: an overview","volume":"72","author":"Golden","year":"2005","journal-title":"Am Fam Physician"},{"issue":"6","key":"10.1016\/j.tube.2017.04.004_bib33","doi-asserted-by":"crossref","first-page":"2581","DOI":"10.1016\/S0021-9258(18)69104-5","article-title":"Mechanism of glucocorticoid receptor down-regulation by glucocorticoids","volume":"263","author":"Rosewicz","year":"1988","journal-title":"J\u00a0Biol Chem"},{"issue":"1","key":"10.1016\/j.tube.2017.04.004_bib34","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1186\/s40348-014-0008-9","article-title":"Are microRNAs suitable biomarkers of immunity to tuberculosis?","volume":"1","author":"Ueberberg","year":"2014","journal-title":"Mol Cell Pediatr"},{"issue":"9","key":"10.1016\/j.tube.2017.04.004_bib35","doi-asserted-by":"crossref","first-page":"861","DOI":"10.1038\/ni.2073","article-title":"The microRNA miR-29 controls innate and adaptive immune responses to intracellular bacterial infection by targeting interferon-gamma","volume":"12","author":"Ma","year":"2011","journal-title":"Nat Immunol"},{"issue":"12","key":"10.1016\/j.tube.2017.04.004_bib36","doi-asserted-by":"crossref","first-page":"4246","DOI":"10.1128\/JCM.05459-11","article-title":"Circulating microRNAs in patients with active pulmonary tuberculosis","volume":"49","author":"Fu","year":"2011","journal-title":"J\u00a0Clin Microbiol"},{"issue":"10","key":"10.1016\/j.tube.2017.04.004_bib37","doi-asserted-by":"crossref","first-page":"e25832","DOI":"10.1371\/journal.pone.0025832","article-title":"Comparative miRNA expression profiles in individuals with latent and active tuberculosis","volume":"6","author":"Wang","year":"2011","journal-title":"PLoS One"},{"issue":"8","key":"10.1016\/j.tube.2017.04.004_bib38","doi-asserted-by":"crossref","first-page":"e43184","DOI":"10.1371\/journal.pone.0043184","article-title":"Altered microRNA signatures in sputum of patients with active pulmonary tuberculosis","volume":"7","author":"Yi","year":"2012","journal-title":"PLoS One"},{"issue":"11","key":"10.1016\/j.tube.2017.04.004_bib39","doi-asserted-by":"crossref","first-page":"e80149","DOI":"10.1371\/journal.pone.0080149","article-title":"miRNA signatures in sera of patients with active pulmonary tuberculosis","volume":"8","author":"Miotto","year":"2013","journal-title":"PLoS One"}],"container-title":["Tuberculosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472979217300173?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472979217300173?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2023,8,23]],"date-time":"2023-08-23T05:50:38Z","timestamp":1692769838000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1472979217300173"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,7]]},"references-count":39,"alternative-id":["S1472979217300173"],"URL":"https:\/\/doi.org\/10.1016\/j.tube.2017.04.004","relation":{},"ISSN":["1472-9792"],"issn-type":[{"value":"1472-9792","type":"print"}],"subject":[],"published":{"date-parts":[[2017,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"miR-30c is specifically repressed in patients with active pulmonary tuberculosis","name":"articletitle","label":"Article Title"},{"value":"Tuberculosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tube.2017.04.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}