{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,4,9]],"date-time":"2025-04-09T20:31:59Z","timestamp":1744230719291},"reference-count":92,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,12,1]],"date-time":"2018-12-01T00:00:00Z","timestamp":1543622400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":["clinicalkey.jp","clinicalkey.com","clinicalkey.es","clinicalkey.fr","clinicalkey.com.au","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Tuberculosis"],"published-print":{"date-parts":[[2018,12]]},"DOI":"10.1016\/j.tube.2018.08.014","type":"journal-article","created":{"date-parts":[[2018,8,31]],"date-time":"2018-08-31T22:31:46Z","timestamp":1535754706000},"page":"30-37","update-policy":"http:\/\/dx.doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":2,"special_numbering":"C","title":["Uncloaking an ancient adversary: Can pathogen biomarker elicitors play a role in confirming extrapulmonary TB and latent TB infection?"],"prefix":"10.1016","volume":"113","author":[{"given":"Brad W.","family":"Porter","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thara K.","family":"Venkatappa","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tube.2018.08.014_bib1","unstructured":"Oxford Immunotec. T-SPOT\u00ae.TB package insert.;PI-TB-US-V5."},{"key":"10.1016\/j.tube.2018.08.014_bib2","series-title":"QuantiFERON\u00ae-TB Gold Plus (QFT\u00ae-Plus) package insert. The whole blood IFN-\u03b3 test measuring responses to ESAT-6 and CFP-10 peptide antigens","author":"Qiagen","year":"2017"},{"key":"10.1016\/j.tube.2018.08.014_bib3","first-page":"102","article-title":"Colonoscopic fine needle aspiration cytology in the diagnosis of ileocecal tuberculosis","volume":"86","author":"Kochhar","year":"1991","journal-title":"Am J Gastroenterol"},{"key":"10.1016\/j.tube.2018.08.014_bib4","doi-asserted-by":"crossref","first-page":"819","DOI":"10.1111\/j.1440-1746.2006.04030.x","article-title":"Use of polymerase chain reaction in the diagnosis of abdominal tuberculosis","volume":"21","author":"Kulkarni","year":"2006","journal-title":"J Gastroenterol Hepatol"},{"key":"10.1016\/j.tube.2018.08.014_bib5","doi-asserted-by":"crossref","first-page":"586","DOI":"10.1177\/014107680309601204","article-title":"Diagnosis of abdominal tuberculosis: the importance of laparoscopy","volume":"96","author":"Rai","year":"2003","journal-title":"J R Soc Med"},{"key":"10.1016\/j.tube.2018.08.014_bib6","first-page":"150","article-title":"Abdominal tuberculosis: diagnosis by laparoscopy and colonoscopy","volume":"23","author":"Ibrarullah","year":"2002","journal-title":"Trop Gastroenterol"},{"key":"10.1016\/j.tube.2018.08.014_bib7","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1080\/00365549950164111","article-title":"Abdominal tuberculosis: the problem of diagnostic delay","volume":"31","author":"Singh-Ranger","year":"1999","journal-title":"Scand J Infect Dis"},{"key":"10.1016\/j.tube.2018.08.014_bib8","doi-asserted-by":"crossref","first-page":"1176","DOI":"10.1038\/ng.2744","article-title":"Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans","volume":"45","author":"Comas","year":"2013","journal-title":"Nat Genet"},{"key":"10.1016\/j.tube.2018.08.014_bib9","doi-asserted-by":"crossref","first-page":"1497","DOI":"10.1016\/j.cell.2014.11.024","article-title":"Host evasion and exploitation schemes of Mycobacterium tuberculosis","volume":"159","author":"Cambier","year":"2014","journal-title":"Cell"},{"key":"10.1016\/j.tube.2018.08.014_bib10","doi-asserted-by":"crossref","first-page":"295","DOI":"10.4049\/jimmunol.1400092","article-title":"Mycobacterium tuberculosis keto-mycolic acid and macrophage nuclear receptor TR4 modulate foamy biogenesis in granulomas: a case of a heterologous and noncanonical ligand-receptor pair","volume":"193","author":"Dkhar","year":"2014","journal-title":"J Immunol"},{"key":"10.1016\/j.tube.2018.08.014_bib11","doi-asserted-by":"crossref","first-page":"2582","DOI":"10.1093\/jac\/dkq374","article-title":"Time-kill kinetics of anti-tuberculosis drugs, and emergence of resistance, in relation to metabolic activity of Mycobacterium tuberculosis","volume":"65","author":"de Steenwinkel","year":"2010","journal-title":"J Antimicrob Chemother"},{"key":"10.1016\/j.tube.2018.08.014_bib12","doi-asserted-by":"crossref","first-page":"1300","DOI":"10.1086\/319679","article-title":"A whole blood bactericidal assay for tuberculosis","volume":"183","author":"Wallis","year":"2001","journal-title":"J Infect Dis"},{"key":"10.1016\/j.tube.2018.08.014_bib13","doi-asserted-by":"crossref","first-page":"3969","DOI":"10.1073\/pnas.1621360114","article-title":"Quantification of circulating Mycobacterium tuberculosis antigen peptides allows rapid diagnosis of active disease and treatment monitoring","volume":"114","author":"Liu","year":"2017","journal-title":"Proc Natl Acad Sci U. S. A."},{"issue":"Pt 2","key":"10.1016\/j.tube.2018.08.014_bib14","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1099\/00221287-146-2-289","article-title":"InhA, a target of the antituberculous drug isoniazid, is involved in a mycobacterial fatty acid elongation system, FAS-II","volume":"146","author":"Marrakchi","year":"2000","journal-title":"Microbiology"},{"key":"10.1016\/j.tube.2018.08.014_bib15","series-title":"Guidelines on the management of latent tuberculosis infection","author":"World Health Organization","year":"2015"},{"key":"10.1016\/j.tube.2018.08.014_bib16","doi-asserted-by":"crossref","first-page":"1220","DOI":"10.1111\/j.1365-2958.2006.05467.x","article-title":"Mechanisms of action of isoniazid","volume":"62","author":"Timmins","year":"2006","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.tube.2018.08.014_bib17","doi-asserted-by":"crossref","first-page":"514","DOI":"10.1016\/j.drudis.2011.12.013","article-title":"Understanding latent tuberculosis: the key to improved diagnostic and novel treatment strategies","volume":"17","author":"Esmail","year":"2012","journal-title":"Drug Discov Today"},{"key":"10.1016\/j.tube.2018.08.014_bib18","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1146\/annurev.micro.112408.134043","article-title":"Letting sleeping dos lie: does dormancy play a role in tuberculosis?","volume":"64","author":"Chao","year":"2010","journal-title":"Annu Rev Microbiol"},{"key":"10.1016\/j.tube.2018.08.014_bib19","series-title":"Treatment of tuberculosis guidelines","author":"World Health Organization","year":"2010"},{"key":"10.1016\/j.tube.2018.08.014_bib20","doi-asserted-by":"crossref","first-page":"901","DOI":"10.1016\/S0092-8674(01)00286-0","article-title":"Structural mechanism for rifampicin inhibition of bacterial RNA polymerase","volume":"104","author":"Campbell","year":"2001","journal-title":"Cell"},{"key":"10.1016\/j.tube.2018.08.014_bib21","doi-asserted-by":"crossref","first-page":"D1202","DOI":"10.1093\/nar\/gkv951","article-title":"PubChem substance and compound databases","volume":"44","author":"Kim","year":"2016","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.tube.2018.08.014_bib22","doi-asserted-by":"crossref","first-page":"1496","DOI":"10.1039\/C3LC51124C","article-title":"Microfluidic platforms for biomarker analysis","volume":"14","author":"Nahavandi","year":"2014","journal-title":"Lab Chip"},{"key":"10.1016\/j.tube.2018.08.014_bib23","doi-asserted-by":"crossref","first-page":"537","DOI":"10.1038\/31159","article-title":"Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence","volume":"393","author":"Cole","year":"1998","journal-title":"Nature"},{"key":"10.1016\/j.tube.2018.08.014_bib24","doi-asserted-by":"crossref","first-page":"2967","DOI":"10.1099\/00221287-148-10-2967","article-title":"Re-annotation of the genome sequence of Mycobacterium tuberculosis H37Rv","volume":"148","author":"Camus","year":"2002","journal-title":"Microbiology"},{"key":"10.1016\/j.tube.2018.08.014_bib25","doi-asserted-by":"crossref","first-page":"5133","DOI":"10.1073\/pnas.0610634104","article-title":"Lipidomics reveals control of Mycobacterium tuberculosis virulence lipids via metabolic coupling","volume":"104","author":"Jain","year":"2007","journal-title":"Proc Natl Acad Sci U. S. A."},{"key":"10.1016\/j.tube.2018.08.014_bib26","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.MGM2-0029-2013","article-title":"Noncoding RNA in mycobacteria","volume":"2","author":"Arnvig","year":"2014","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.tube.2018.08.014_bib27","doi-asserted-by":"crossref","first-page":"2951","DOI":"10.1099\/00221287-148-10-2951","article-title":"Intracellular lipophilic inclusions of mycobacteria in vitro and in sputum","volume":"148","author":"Garton","year":"2002","journal-title":"Microbiology"},{"key":"10.1016\/j.tube.2018.08.014_bib28","doi-asserted-by":"crossref","first-page":"D535","DOI":"10.1093\/nar\/gkw1017","article-title":"Improvements to PATRIC, the all-bacterial bioinformatics database and analysis resource center","volume":"45","author":"Wattam","year":"2017","journal-title":"Nucleic Acids Res"},{"key":"10.1016\/j.tube.2018.08.014_bib29","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0106434","article-title":"Search for microRNAs expressed by intracellular bacterial pathogens in infected mammalian cells","volume":"9","author":"Furuse","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.tube.2018.08.014_bib30","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.tube.2010.09.008","article-title":"Tuberculist--10 years after","volume":"91","author":"Lew","year":"2011","journal-title":"Tuberculosis (Edin, Scotl)"},{"key":"10.1016\/j.tube.2018.08.014_bib31","doi-asserted-by":"crossref","first-page":"1537","DOI":"10.1016\/j.chembiol.2011.10.013","article-title":"A comparative lipidomics platform for chemotaxonomic analysis of Mycobacterium tuberculosis","volume":"18","author":"Layre","year":"2011","journal-title":"Chem Biol"},{"key":"10.1016\/j.tube.2018.08.014_bib32","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.MGM2-0033-2013","article-title":"Mycobacterial lipidomics","volume":"2","author":"Layre","year":"2014","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.tube.2018.08.014_bib33","doi-asserted-by":"crossref","first-page":"26","DOI":"10.1016\/j.tube.2014.10.010","article-title":"Deciphering the role of exosomes in tuberculosis","volume":"95","author":"Kruh-Garcia","year":"2015","journal-title":"Tuberculosis (Edinb, Scotl)"},{"key":"10.1016\/j.tube.2018.08.014_bib34","doi-asserted-by":"crossref","first-page":"3164","DOI":"10.1128\/JCM.00801-14","article-title":"Improved sensitivity for molecular detection of bacterial and Candida infections in blood","volume":"52","author":"Bacconi","year":"2014","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.tube.2018.08.014_bib35","doi-asserted-by":"crossref","DOI":"10.1002\/0471142727.mb1514s105","article-title":"Loop-mediated isothermal amplification for detection of nucleic acids","volume":"105","author":"Tanner","year":"2014","journal-title":"Curr Protoc Mol Biol"},{"key":"10.1016\/j.tube.2018.08.014_bib36","doi-asserted-by":"crossref","first-page":"791","DOI":"10.1373\/clinchem.2017.273698","article-title":"Clinical evaluation of a blood assay to diagnose paucibacillary tuberculosis via bacterial antigens","volume":"64","author":"Liu","year":"2018","journal-title":"Clin Chem"},{"key":"10.1016\/j.tube.2018.08.014_bib37","doi-asserted-by":"crossref","DOI":"10.4084\/mjhid.2013.070","article-title":"The biology of Mycobacterium tuberculosis infection","volume":"5","author":"Delogu","year":"2013","journal-title":"Mediterr J Hematol Infect Dis"},{"key":"10.1016\/j.tube.2018.08.014_bib38","doi-asserted-by":"crossref","first-page":"1913","DOI":"10.1128\/AAC.00869-05","article-title":"Detection of live and antibiotic-killed bacteria by quantitative real-time PCR of specific fragments of rRNA","volume":"50","author":"Aellen","year":"2006","journal-title":"Antimicrob Agents Chemother"},{"key":"10.1016\/j.tube.2018.08.014_bib39","doi-asserted-by":"crossref","first-page":"4435","DOI":"10.1128\/JCM.41.9.4435-4437.2003","article-title":"Streptococcus pneumoniae endocarditis: persistence of DNA on heart valve material 7 years after infectious episode","volume":"41","author":"Branger","year":"2003","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.tube.2018.08.014_bib40","series-title":"RNA from blood, user manual. NucleoSpin\u00ae RNA blood, NucleoSpin\u00ae RNA Blood Midi","author":"Macherey-Nagel","year":"2017"},{"key":"10.1016\/j.tube.2018.08.014_bib41","doi-asserted-by":"crossref","first-page":"244","DOI":"10.1002\/jcla.20174","article-title":"Comparison of manual and automated nucleic acid extraction from whole-blood samples","volume":"21","author":"Riemann","year":"2007","journal-title":"J Clin Lab Anal"},{"key":"10.1016\/j.tube.2018.08.014_bib42","doi-asserted-by":"crossref","first-page":"313","DOI":"10.13110\/humanbiology.86.4.0313","article-title":"How much DNA is lost? Measuring DNA loss of short-tandem-repeat length fragments targeted by the PowerPlex 16\u00ae system using the Qiagen MinElute purification kit","volume":"86","author":"Kemp","year":"2014","journal-title":"Hum Biol"},{"key":"10.1016\/j.tube.2018.08.014_bib43","doi-asserted-by":"crossref","first-page":"156","DOI":"10.1016\/0003-2697(87)90021-2","article-title":"Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction","volume":"162","author":"Chomczynski","year":"1987","journal-title":"Anal Biochem"},{"key":"10.1016\/j.tube.2018.08.014_bib44","first-page":"148","article-title":"An improvement of the single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction","volume":"8","author":"Puissant","year":"1990","journal-title":"Biotechniques"},{"key":"10.1016\/j.tube.2018.08.014_bib45","doi-asserted-by":"crossref","first-page":"581","DOI":"10.1038\/nprot.2006.83","article-title":"The single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction: twenty-something years on","volume":"1","author":"Chomczynski","year":"2006","journal-title":"Nat Protoc"},{"key":"10.1016\/j.tube.2018.08.014_bib46","article-title":"Isolation of high-molecular-weight DNA from mammalian blood using Proteinase K and phenol","author":"Green","year":"2017","journal-title":"Cold Spring Harb Protoc"},{"key":"10.1016\/j.tube.2018.08.014_bib47","article-title":"Isolation of high-molecular-weight DNA from mammalian cells using Proteinase K and phenol","author":"Sambrook","year":"2006","journal-title":"Cold Spring Harb Protoc"},{"key":"10.1016\/j.tube.2018.08.014_bib48","series-title":"Rapid isolation of RNA by guanidinium thiocyanate\/cesium chloride gradient using Thermo Scientific Fiberlite ultracentrifuge rotors","author":"Griffith","year":"2010"},{"key":"10.1016\/j.tube.2018.08.014_bib49","series-title":"Molecular cloning: a laboratory manual","author":"Sambrook","year":"2001"},{"key":"10.1016\/j.tube.2018.08.014_bib50","doi-asserted-by":"crossref","first-page":"473","DOI":"10.1534\/genetics.114.165498","article-title":"Selective whole genome amplification for resequencing target microbial species from complex natural samples","volume":"198","author":"Leichty","year":"2014","journal-title":"Genetics"},{"issue":"1","key":"10.1016\/j.tube.2018.08.014_bib51","doi-asserted-by":"crossref","DOI":"10.1128\/mBio.02257-16","article-title":"Selective whole-genome amplification is a robust method that enables scalable whole-genome sequencing of Plasmodium vivax from unprocessed clinical samples","volume":"8","author":"Cowell","year":"2017","journal-title":"mBio"},{"key":"10.1016\/j.tube.2018.08.014_bib52","doi-asserted-by":"crossref","first-page":"777","DOI":"10.1093\/clinchem\/45.6.777","article-title":"Strand displacement amplification and homogeneous real-time detection incorporated in a second-generation DNA probe system, BDProbeTecET","volume":"45","author":"Little","year":"1999","journal-title":"Clin Chem"},{"key":"10.1016\/j.tube.2018.08.014_bib53","first-page":"364","article-title":"Performance of the BD ProbeTec ET direct detection assay for the analysis of Mycobacterium tuberculosis in respiratory and non-respiratory clinical specimens","volume":"12","author":"Somily","year":"2017","journal-title":"J Taibah Univ Med Sci"},{"key":"10.1016\/j.tube.2018.08.014_bib54","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1128\/JCM.01463-09","article-title":"Rapid detection of Mycobacterium tuberculosis and rifampin resistance by use of on-demand, near-patient technology","volume":"48","author":"Helb","year":"2010","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.tube.2018.08.014_bib55","doi-asserted-by":"crossref","first-page":"2112","DOI":"10.1128\/JCM.00142-13","article-title":"Evaluation of COBAS TaqMan MTB for direct detection of the Mycobacterium tuberculosis complex in comparison with COBAS Amplicor MTB","volume":"51","author":"Bloemberg","year":"2013","journal-title":"J Clin Microbiol"},{"key":"10.1016\/j.tube.2018.08.014_bib56","doi-asserted-by":"crossref","first-page":"1102","DOI":"10.5588\/ijtld.14.0472","article-title":"Conventional and real-time PCR targeting 16S ribosomal RNA for the detection of Mycobacterium tuberculosis complex","volume":"19","author":"Choi","year":"2015","journal-title":"Int J Tubercul Lung Dis"},{"key":"10.1016\/j.tube.2018.08.014_bib57","doi-asserted-by":"crossref","first-page":"7747","DOI":"10.1021\/acs.analchem.8b01807","article-title":"Detection of PCR-amplified tuberculosis DNA fragments with polyelectrolyte-modified field-effect sensors","volume":"90","author":"Bronder","year":"2018","journal-title":"Anal Chem"},{"key":"10.1016\/j.tube.2018.08.014_bib58","doi-asserted-by":"crossref","first-page":"5816","DOI":"10.1021\/pr1005873","article-title":"Proteomic definition of the cell wall of Mycobacterium tuberculosis","volume":"9","author":"Wolfe","year":"2010","journal-title":"J Proteome Res"},{"key":"10.1016\/j.tube.2018.08.014_bib59","doi-asserted-by":"crossref","first-page":"672","DOI":"10.1038\/nsmb.3064","article-title":"The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD","volume":"22","author":"Sun","year":"2015","journal-title":"Nat Struct Mol Biol"},{"key":"10.1016\/j.tube.2018.08.014_bib60","doi-asserted-by":"crossref","first-page":"527","DOI":"10.1093\/cid\/civ323","article-title":"Flu-like and other systemic drug reactions among persons receiving weekly rifapentine plus isoniazid or daily isoniazid for treatment of latent tuberculosis infection in the PREVENT tuberculosis study","volume":"61","author":"Sterling","year":"2015","journal-title":"Clin Infect Dis Off Publ Infect Dis Soc Am"},{"key":"10.1016\/j.tube.2018.08.014_bib61","doi-asserted-by":"crossref","first-page":"6750","DOI":"10.1073\/pnas.1400136111","article-title":"An outer membrane channel protein of Mycobacterium tuberculosis with exotoxin activity","volume":"111","author":"Danilchanka","year":"2014","journal-title":"Proc Natl Acad Sci U. S. A."},{"key":"10.1016\/j.tube.2018.08.014_bib62","doi-asserted-by":"crossref","first-page":"24213","DOI":"10.1074\/jbc.M113.473371","article-title":"MmpL11 protein transports mycolic acid-containing lipids to the mycobacterial cell wall and contributes to biofilm formation in Mycobacterium smegmatis","volume":"288","author":"Pacheco","year":"2013","journal-title":"J Biol Chem"},{"key":"10.1016\/j.tube.2018.08.014_bib63","doi-asserted-by":"crossref","DOI":"10.1128\/IAI.00131-17","article-title":"The Mycobacterium tuberculosis MmpL11 cell wall lipid transporter is important for biofilm formation, intracellular growth, and nonreplicating persistence","volume":"85","author":"Wright","year":"2017","journal-title":"Infect Immun"},{"key":"10.1016\/j.tube.2018.08.014_bib64","doi-asserted-by":"crossref","first-page":"889","DOI":"10.1111\/mmi.13675","article-title":"The diverse family of MmpL transporters in mycobacteria: from regulation to antimicrobial developments","volume":"104","author":"Viljoen","year":"2017","journal-title":"Mol Microbiol"},{"key":"10.1016\/j.tube.2018.08.014_bib65","doi-asserted-by":"crossref","first-page":"702","DOI":"10.1021\/acsinfecdis.6b00095","article-title":"Structure-function profile of MmpL3, the essential mycolic acid transporter from Mycobacterium tuberculosis","volume":"2","author":"Belardinelli","year":"2016","journal-title":"ACS Infect Dis"},{"key":"10.1016\/j.tube.2018.08.014_bib66","doi-asserted-by":"crossref","first-page":"7993","DOI":"10.1073\/pnas.1700062114","article-title":"MmpL3 is the flippase for mycolic acids in mycobacteria","volume":"114","author":"Xu","year":"2017","journal-title":"Proc Natl Acad Sci U. S. A."},{"key":"10.1016\/j.tube.2018.08.014_bib67","doi-asserted-by":"crossref","first-page":"550","DOI":"10.1038\/nrmicro3299","article-title":"How sisters grow apart: mycobacterial growth and division","volume":"12","author":"Kieser","year":"2014","journal-title":"Nat Rev Microbiol"},{"key":"10.1016\/j.tube.2018.08.014_bib68","doi-asserted-by":"crossref","first-page":"1326","DOI":"10.1086\/378563","article-title":"Cell-wall alterations as an attribute of Mycobacterium tuberculosis in latent infection","volume":"188","author":"Seiler","year":"2003","journal-title":"J Infect Dis"},{"issue":"18","key":"10.1016\/j.tube.2018.08.014_bib69","first-page":"30067","article-title":"Cell wall enrichment unveils proteomic changes in the cell wall during treatment of Mycobacterium smegmatis with sub-lethal concentrations of rifampicin","author":"Hermann","year":"2018","journal-title":"J Proteom"},{"key":"10.1016\/j.tube.2018.08.014_bib70","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.MGM2-0020-2013","article-title":"Mycobacterium tuberculosis in the proteomics era","volume":"2","author":"Gengenbacher","year":"2014","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.tube.2018.08.014_bib71","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1016\/j.mimet.2016.10.021","article-title":"Optimizing of a protein extraction method for Mycobacterium tuberculosis proteome analysis using mass spectrometry","volume":"131","author":"Rabodoarivelo","year":"2016","journal-title":"J Microbiol Meth"},{"key":"10.1016\/j.tube.2018.08.014_bib72","doi-asserted-by":"crossref","first-page":"218","DOI":"10.1038\/nature12799","article-title":"Mycobacteria manipulate macrophage recruitment through coordinated use of membrane lipids","volume":"505","author":"Cambier","year":"2014","journal-title":"Nature"},{"key":"10.1016\/j.tube.2018.08.014_bib73","doi-asserted-by":"crossref","first-page":"4958","DOI":"10.1073\/pnas.1403078111","article-title":"Mycobacterial outer membrane is a lipid bilayer and the inner membrane is unusually rich in diacyl phosphatidylinositol dimannosides","volume":"111","author":"Bansal-Mutalik","year":"2014","journal-title":"Proc Natl Acad Sci U. S. A."},{"key":"10.1016\/j.tube.2018.08.014_bib74","series-title":"Tuberculosis - expanding knowledge","first-page":"145","article-title":"Pathophysiological implications of cell envelope structure in Mycobacterium tuberculosis and related taxa","author":"Minnikin","year":"2015"},{"key":"10.1016\/j.tube.2018.08.014_bib75","doi-asserted-by":"crossref","first-page":"27","DOI":"10.1002\/emmm.201100185","article-title":"Mycolic acids as diagnostic markers for tuberculosis case detection in humans and drug efficacy in mice","volume":"4","author":"Shui","year":"2012","journal-title":"EMBO Mol Med"},{"key":"10.1016\/j.tube.2018.08.014_bib76","doi-asserted-by":"crossref","first-page":"2924","DOI":"10.1194\/jlr.D036137","article-title":"Novel phage display-derived mycolic acid-specific antibodies with potential for tuberculosis diagnosis","volume":"54","author":"Chan","year":"2013","journal-title":"J Lipid Res"},{"key":"10.1016\/j.tube.2018.08.014_bib77","doi-asserted-by":"crossref","DOI":"10.1101\/cshperspect.a021105","article-title":"The mycobacterial cell envelope\u2014lipids","volume":"4","author":"Jackson","year":"2014","journal-title":"Cold Spring Harbor Perspect Med"},{"key":"10.1016\/j.tube.2018.08.014_bib78","doi-asserted-by":"crossref","first-page":"4574","DOI":"10.1128\/IAI.00222-09","article-title":"Mycobacterium tuberculosis cell wall glycolipids directly inhibit CD4+ T-cell activation by interfering with proximal T-cell-receptor signaling","volume":"77","author":"Mahon","year":"2009","journal-title":"Infect Immun"},{"key":"10.1016\/j.tube.2018.08.014_bib79","doi-asserted-by":"crossref","first-page":"98","DOI":"10.1016\/j.cellimm.2012.02.009","article-title":"Mycobacterium tuberculosis ManLAM inhibits T-cell-receptor signaling by interference with ZAP-70, Lck and LAT phosphorylation","volume":"275","author":"Mahon","year":"2012","journal-title":"Cell Immunol"},{"key":"10.1016\/j.tube.2018.08.014_bib80","doi-asserted-by":"crossref","first-page":"10281","DOI":"10.1038\/srep10281","article-title":"The diagnostic targeting of a carbohydrate virulence factor from M. tuberculosis","volume":"5","author":"Chan","year":"2015","journal-title":"Sci Rep"},{"key":"10.1016\/j.tube.2018.08.014_bib81","doi-asserted-by":"crossref","first-page":"314","DOI":"10.1073\/pnas.0305439101","article-title":"A polyketide synthase catalyzes the last condensation step of mycolic acid biosynthesis in mycobacteria and related organisms","volume":"101","author":"Portevin","year":"2004","journal-title":"Proc Natl Acad Sci U. S. A."},{"key":"10.1016\/j.tube.2018.08.014_bib82","doi-asserted-by":"crossref","first-page":"179","DOI":"10.3109\/10409238.2014.896859","article-title":"Biosynthesis of mycobacterial lipids by polyketide synthases and beyond","volume":"49","author":"Quadri","year":"2014","journal-title":"Crit Rev Biochem Mol Biol"},{"key":"10.1016\/j.tube.2018.08.014_bib83","doi-asserted-by":"crossref","first-page":"84","DOI":"10.1038\/nature02837","article-title":"A glycolipid of hypervirulent tuberculosis strains that inhibits the innate immune response","volume":"431","author":"Reed","year":"2004","journal-title":"Nature"},{"key":"10.1016\/j.tube.2018.08.014_bib84","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s12915-017-0471-6","article-title":"Phthiocerol dimycocerosates promote access to the cytosol and intracellular burden of Mycobacterium tuberculosis in lymphatic endothelial cells","volume":"16","author":"Lerner","year":"2018","journal-title":"BMC Biol"},{"key":"10.1016\/j.tube.2018.08.014_bib85","doi-asserted-by":"crossref","first-page":"195","DOI":"10.1111\/cmi.12214","article-title":"Multiple deletions in the polyketide synthase gene repertoire of Mycobacterium tuberculosis reveal functional overlap of cell envelope lipids in host-pathogen interactions","volume":"16","author":"Passemar","year":"2014","journal-title":"Cell Microbiol"},{"key":"10.1016\/j.tube.2018.08.014_bib86","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0108854","article-title":"Plasma metabolomics in human pulmonary tuberculosis disease: a pilot study","volume":"9","author":"Frediani","year":"2014","journal-title":"PLoS One"},{"key":"10.1016\/j.tube.2018.08.014_bib87","doi-asserted-by":"crossref","DOI":"10.1128\/microbiolspec.TNMI7-0046-2017","article-title":"Musculoskeletal tuberculosis","volume":"5","author":"Leonard","year":"2017","journal-title":"Microbiol Spectr"},{"key":"10.1016\/j.tube.2018.08.014_bib88","doi-asserted-by":"crossref","first-page":"1194","DOI":"10.1093\/infdis\/jis381","article-title":"Extrapulmonary locations of Mycobacterium tuberculosis DNA during latent infection","volume":"206","author":"Barrios-Payan","year":"2012","journal-title":"J Infect Dis"},{"key":"10.1016\/j.tube.2018.08.014_bib89","doi-asserted-by":"crossref","first-page":"228","DOI":"10.4103\/1817-1745.123687","article-title":"Disseminated tuberculosis with paradoxical miliary tuberculomas of brain in a child with rickets","volume":"8","author":"Patel","year":"2013","journal-title":"J Pediatr Neurosci"},{"key":"10.1016\/j.tube.2018.08.014_bib90","doi-asserted-by":"crossref","first-page":"e62","DOI":"10.1136\/emj.2006.040279","article-title":"A case of miliary tuberculosis presenting with bowel perforation","volume":"23","author":"Muquit","year":"2006","journal-title":"Emerg Med J"},{"key":"10.1016\/j.tube.2018.08.014_bib91","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2014-006833","article-title":"Urine lipoarabinomannan to monitor antituberculosis therapy response and predict mortality in an HIV-endemic region: a prospective cohort study","volume":"5","author":"Drain","year":"2015","journal-title":"BMJ Open"},{"key":"10.1016\/j.tube.2018.08.014_bib92","first-page":"146","article-title":"Mycobacterium tuberculosis DNA detection in soluble fraction of urine from pulmonary tuberculosis patients","volume":"12","author":"Cannas","year":"2008","journal-title":"Int J Tubercul Lung Dis"}],"container-title":["Tuberculosis"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472979218301525?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1472979218301525?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2020,11,8]],"date-time":"2020-11-08T16:54:50Z","timestamp":1604854490000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1472979218301525"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,12]]},"references-count":92,"alternative-id":["S1472979218301525"],"URL":"https:\/\/doi.org\/10.1016\/j.tube.2018.08.014","relation":{},"ISSN":["1472-9792"],"issn-type":[{"value":"1472-9792","type":"print"}],"subject":[],"published":{"date-parts":[[2018,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Uncloaking an ancient adversary: Can pathogen biomarker elicitors play a role in confirming extrapulmonary TB and latent TB infection?","name":"articletitle","label":"Article Title"},{"value":"Tuberculosis","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tube.2018.08.014","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2018 Elsevier Ltd. All rights reserved.","name":"copyright","label":"Copyright"}]}}