{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,17]],"date-time":"2026-08-17T20:16:44Z","timestamp":1786997804361,"version":"build-2736575974"},"reference-count":18,"publisher":"Elsevier BV","issue":"1","license":[{"start":{"date-parts":[[2012,7,1]],"date-time":"2012-07-01T00:00:00Z","timestamp":1341100800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Veterinary Journal"],"published-print":{"date-parts":[[2012,7]]},"DOI":"10.1016\/j.tvjl.2011.09.011","type":"journal-article","created":{"date-parts":[[2011,11,3]],"date-time":"2011-11-03T03:35:02Z","timestamp":1320291302000},"page":"283-286","source":"Crossref","is-referenced-by-count":25,"title":["Genome-wide analysis of mitral valve disease in Cavalier King Charles Spaniels"],"prefix":"10.1016","volume":"193","author":[{"given":"Anne T.","family":"French","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rob","family":"Ogden","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cathlene","family":"Eland","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gibran","family":"Hemani","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ricardo","family":"Pong-Wong","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brendan","family":"Corcoran","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kim M.","family":"Summers","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tvjl.2011.09.011_b0005","doi-asserted-by":"crossref","first-page":"1023","DOI":"10.2460\/javma.1993.203.07.1023","article-title":"Chronic mitral valve disease in Cavalier King Charles Spaniels: 95 cases (1987\u20131991)","volume":"203","author":"Beardow","year":"1993","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"10.1016\/j.tvjl.2011.09.011_b0010","doi-asserted-by":"crossref","first-page":"120","DOI":"10.1111\/j.1939-1676.2007.0008.x","article-title":"Survival characteristics and prognostic variables of dogs with mitral regurgitation attributable to myxomatous valve disease","volume":"22","author":"Borgarelli","year":"2008","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"10.1016\/j.tvjl.2011.09.011_b0015","doi-asserted-by":"crossref","first-page":"365","DOI":"10.1136\/vr.120.15.365","article-title":"Valvular incompetence in Cavalier King Charles Spaniels","volume":"120","author":"Darke","year":"1987","journal-title":"Veterinary Record"},{"key":"10.1016\/j.tvjl.2011.09.011_b0030","doi-asserted-by":"crossref","first-page":"1462","DOI":"10.1126\/science.1162525","article-title":"A mutation in hairless dogs implicates FOXI3 in ectodermal development","volume":"321","author":"Drogemuller","year":"2008","journal-title":"Science"},{"key":"10.1016\/j.tvjl.2011.09.011_b0020","doi-asserted-by":"crossref","first-page":"e1000579","DOI":"10.1371\/journal.pgen.1000579","article-title":"A missense mutation in the SERPINH1 gene in Dachshunds with osteogenesis imperfecta","volume":"5","author":"Drogemuller","year":"2009","journal-title":"PLoS Genetics"},{"key":"10.1016\/j.tvjl.2011.09.011_b0025","doi-asserted-by":"crossref","first-page":"e11258","DOI":"10.1371\/journal.pone.0011258","article-title":"A deletion in the N-myc downstream regulated gene 1 (NDRG1) gene in Greyhounds with polyneuropathy","volume":"5","author":"Drogemuller","year":"2010","journal-title":"PLoS ONE"},{"key":"10.1016\/j.tvjl.2011.09.011_b0035","first-page":"1549","article-title":"An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9","volume":"16","author":"Goldstein","year":"2010","journal-title":"Molecular Vision"},{"key":"10.1016\/j.tvjl.2011.09.011_b0040","series-title":"Canine and Feline Cardiology","first-page":"29","article-title":"The clinical approach to heart disease: History and physical examination","author":"Gompf","year":"1988"},{"key":"10.1016\/j.tvjl.2011.09.011_b0045","doi-asserted-by":"crossref","first-page":"67","DOI":"10.4142\/jvs.2005.6.1.67","article-title":"Mitral valve prolapse in Cavalier King Charles Spaniel: A review and case study","volume":"6","author":"Hyun","year":"2005","journal-title":"Journal of Veterinary Science"},{"key":"10.1016\/j.tvjl.2011.09.011_b0050","doi-asserted-by":"crossref","first-page":"357","DOI":"10.1016\/j.mcp.2010.07.007","article-title":"Generalized progressive retinal atrophy in the Irish Glen of Imaal Terrier is associated with a deletion in the ADAM9 gene","volume":"24","author":"Kropatsch","year":"2010","journal-title":"Molecular and Cellular Probes"},{"key":"10.1016\/j.tvjl.2011.09.011_b0055","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1126\/science.2884728","article-title":"Homozygosity mapping: A way to map human recessive traits with the DNA of inbred children","volume":"236","author":"Lander","year":"1987","journal-title":"Science"},{"key":"10.1016\/j.tvjl.2011.09.011_b0060","doi-asserted-by":"crossref","first-page":"73","DOI":"10.1016\/j.tvjl.2010.02.016","article-title":"Heritability of premature mitral valve disease in Cavalier King Charles Spaniels","volume":"188","author":"Lewis","year":"2011","journal-title":"The Veterinary Journal"},{"key":"10.1016\/j.tvjl.2011.09.011_b0065","doi-asserted-by":"crossref","first-page":"54","DOI":"10.1186\/1751-0147-52-54","article-title":"Evaluation of the Swedish breeding program for Cavalier King Charles Spaniels","volume":"52","author":"Lundin","year":"2010","journal-title":"Acta Veterinaria Scandinavica"},{"issue":"Suppl. 1","key":"10.1016\/j.tvjl.2011.09.011_b0095","doi-asserted-by":"crossref","first-page":"S62","DOI":"10.1093\/jhered\/esr041","article-title":"Identification of 2 loci associated with development of myxomatous mitral valve disease in Cavalier King Charles Spaniels","volume":"102","author":"Madsen","year":"2011","journal-title":"Journal of Heredity"},{"key":"10.1016\/j.tvjl.2011.09.011_b0075","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1136\/vr.130.14.302","article-title":"Prevalence of mitral valve insufficiency in Cavalier King Charles Spaniels","volume":"130","author":"Malik","year":"1992","journal-title":"Veterinary Record"},{"key":"10.1016\/j.tvjl.2011.09.011_b0080","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1136\/vr.144.12.315","article-title":"Echocardiographic mitral valve prolapse in Cavalier King Charles Spaniels: Epidemiology and prognostic significance for regurgitation","volume":"144","author":"Pedersen","year":"1999","journal-title":"Veterinary Record"},{"key":"10.1016\/j.tvjl.2011.09.011_b0085","doi-asserted-by":"crossref","first-page":"e1000310","DOI":"10.1371\/journal.pbio.1000310","article-title":"Canine morphology: Hunting for genes and tracking mutations","volume":"8","author":"Shearin","year":"2010","journal-title":"PLoS Biology"},{"key":"10.1016\/j.tvjl.2011.09.011_b0090","doi-asserted-by":"crossref","first-page":"505","DOI":"10.1111\/j.1748-5827.1996.tb01755.x","article-title":"The problem of inherited diseases. 5: Valvular disease in Cavalier King Charles Spaniels","volume":"37","author":"Swift","year":"1996","journal-title":"Journal of Small Animal Practice"}],"container-title":["The Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090023311003650?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090023311003650?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,4,14]],"date-time":"2024-04-14T07:00:56Z","timestamp":1713078056000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1090023311003650"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,7]]},"references-count":18,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2012,7]]}},"alternative-id":["S1090023311003650"],"URL":"https:\/\/doi.org\/10.1016\/j.tvjl.2011.09.011","relation":{},"ISSN":["1090-0233"],"issn-type":[{"value":"1090-0233","type":"print"}],"subject":[],"published":{"date-parts":[[2012,7]]}}}