{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,3]],"date-time":"2026-06-03T08:21:19Z","timestamp":1780474879687,"version":"3.54.1"},"reference-count":21,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2018,4,1]],"date-time":"2018-04-01T00:00:00Z","timestamp":1522540800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"funder":[{"DOI":"10.13039\/100012895","name":"Zoetis","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012895","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100000268","name":"BBSRC","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000268","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Veterinary Journal"],"published-print":{"date-parts":[[2018,4]]},"DOI":"10.1016\/j.tvjl.2017.12.012","type":"journal-article","created":{"date-parts":[[2017,12,15]],"date-time":"2017-12-15T18:12:32Z","timestamp":1513361552000},"page":"85-90","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":20,"special_numbering":"C","title":["An investigation of mechanical nociceptive thresholds in dogs with hind limb joint pain compared to healthy control dogs"],"prefix":"10.1016","volume":"234","author":[{"given":"L.K.","family":"Harris","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"H.R.","family":"Whay","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.C.","family":"Murrell","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.tvjl.2017.12.012_bib0005","doi-asserted-by":"crossref","first-page":"573","DOI":"10.1016\/j.pain.2010.04.003","article-title":"Sensitization in patients with painful knee osteoarthritis","volume":"149","author":"Arendt-Nielsen","year":"2010","journal-title":"Pain"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0010","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1016\/j.tvjl.2013.10.025","article-title":"Feasibility and repeatability of cold and mechanical quantitative sensory testing in normal dogs","volume":"199","author":"Briley","year":"2014","journal-title":"Veterinary Journal"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0015","doi-asserted-by":"crossref","first-page":"155","DOI":"10.1037\/0033-2909.112.1.155","article-title":"A power primer","volume":"112","author":"Cohen","year":"1992","journal-title":"Psychological Bulletin"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0020","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1016\/j.pmr.2005.12.010","article-title":"Central hypersensitivity in chronic pain: mechanisms and clinical implications","volume":"17","author":"Curatolo","year":"2006","journal-title":"Physical Medicine and Rehabilitation Clinics of North America"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0025","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1258\/la.2010.009080","article-title":"A small, silent, low friction, linear actuator for mechanical nociceptive testing in veterinary research","volume":"44","author":"Dixon","year":"2010","journal-title":"Laboratory Animals"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0030","doi-asserted-by":"crossref","first-page":"82","DOI":"10.1016\/j.tvjl.2015.02.008","article-title":"Influence of experimental protocol on response rate and repeatability of mechanical threshold testing in dogs","volume":"204","author":"Harris","year":"2015","journal-title":"The Veterinary Journal"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0035","doi-asserted-by":"crossref","first-page":"1552","DOI":"10.2460\/javma.2003.222.1552","article-title":"Evaluation of methods for assessment of pain associated with chronic osteoarthritis in dogs","volume":"222","author":"Hielm-Bjorkman","year":"2003","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0040","doi-asserted-by":"crossref","first-page":"727","DOI":"10.2460\/ajvr.70.6.727","article-title":"Psychometric testing of the Helsinki chronic pain index by completion of a questionnaire in Finnish by owners of dogs with chronic signs of pain caused by osteoarthritis","volume":"70","author":"Hielm-Bjorkman","year":"2009","journal-title":"American Journal of Veterinary Research"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0045","doi-asserted-by":"crossref","first-page":"297","DOI":"10.1111\/vaa.12003","article-title":"Sedative and analgesic effects of buprenorphine, combined with either acepromazine or dexmedetomidine, for premedication prior to elective surgery in cats and dogs","volume":"40","author":"Hunt","year":"2013","journal-title":"Vetereinary Anaesthesia and Analgesia"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0050","doi-asserted-by":"crossref","first-page":"1089","DOI":"10.2460\/javma.2000.216.1089","article-title":"Effect of weight reduction on clinical signs of lameness in dogs with hip osteoarthritis","volume":"216","author":"Impellizeri","year":"2000","journal-title":"Journal of the American Veterinary Medical Association"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0055","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1136\/vr.c97","article-title":"Review of the safety and efficacy of long-term NSAID use in the treatment of canine osteoarthritis","volume":"166","author":"Innes","year":"2010","journal-title":"Veterinary Record"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0060","doi-asserted-by":"crossref","first-page":"699","DOI":"10.1016\/S0195-5616(97)50076-3","article-title":"Osteoarthritis\u2014Joint anatomy, physiology, and pathobiology","volume":"27","author":"Johnston","year":"1997","journal-title":"Veterinary Clinics of North America-Small Animal Practice"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0065","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pbio.1000412","article-title":"Animal research: Reporting in vivo experiments: The ARRIVE guidelines","volume":"8","author":"Kilkenny","year":"2010","journal-title":"PLoS Biology"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0070","doi-asserted-by":"crossref","first-page":"1325","DOI":"10.1097\/j.pain.0000000000000521","article-title":"Widespread somatosensory sensitivity in naturally occurring canine model of osteoarthritis","volume":"157","author":"Knazovicky","year":"2016","journal-title":"Pain"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0075","doi-asserted-by":"crossref","first-page":"597","DOI":"10.1016\/S0031-6997(24)01514-X","article-title":"Animal models of nociception","volume":"53","author":"Le Bars","year":"2001","journal-title":"Pharmacological Reviews"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0080","doi-asserted-by":"crossref","first-page":"216","DOI":"10.1016\/j.tvjl.2012.11.003","article-title":"The use of an electronic von Frey device for evaluation of sensory threshold in neurologically normal dogs and those with acute spinal cord injury","volume":"197","author":"Moore","year":"2013","journal-title":"Veterinary Journal"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0085","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s11926-010-0131-0","article-title":"The role of quantitative sensory testing in the evaluation of musculoskeletal pain conditions","volume":"12","author":"Pavlakovic","year":"2010","journal-title":"Current Rheumatology Reports"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0090","doi-asserted-by":"crossref","first-page":"1075","DOI":"10.1016\/j.joca.2012.06.009","article-title":"Quantitative sensory testing in painful osteoarthritis: A systematic review and meta-analysis","volume":"20","author":"Suokas","year":"2012","journal-title":"Osteoarthritis and Cartilage"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0095","series-title":"Textbook of Small Animal Surgery","author":"Slatter","year":"1993"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0100","doi-asserted-by":"crossref","first-page":"542","DOI":"10.1111\/j.1532-950X.2014.12160.x","article-title":"Relationship between mechanical thresholds and limb use in dogs with coxofemoral joint oa-associated pain and the modulating effects of pain alleviation from total hip replacement on mechanical thresholds","volume":"43","author":"Tomas","year":"2014","journal-title":"Veterinary Surgery"},{"key":"10.1016\/j.tvjl.2017.12.012_bib0105","doi-asserted-by":"crossref","first-page":"241","DOI":"10.1111\/j.1532-950X.2008.00372.x","article-title":"Relationship between objective and subjective assessment of limb function in normal dogs with an experimentally induced lameness","volume":"37","author":"Waxman","year":"2008","journal-title":"Veterinary Surgery"}],"container-title":["The Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090023317302551?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1090023317302551?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,28]],"date-time":"2025-06-28T21:56:06Z","timestamp":1751147766000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1090023317302551"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":21,"alternative-id":["S1090023317302551"],"URL":"https:\/\/doi.org\/10.1016\/j.tvjl.2017.12.012","relation":{},"ISSN":["1090-0233"],"issn-type":[{"value":"1090-0233","type":"print"}],"subject":[],"published":{"date-parts":[[2018,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"An investigation of mechanical nociceptive thresholds in dogs with hind limb joint pain compared to healthy control dogs","name":"articletitle","label":"Article Title"},{"value":"The Veterinary Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tvjl.2017.12.012","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2017 Published by Elsevier Ltd.","name":"copyright","label":"Copyright"}]}}