{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T10:27:17Z","timestamp":1772706437561,"version":"3.50.1"},"reference-count":16,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2025,6,17]],"date-time":"2025-06-17T00:00:00Z","timestamp":1750118400000},"content-version":"am","delay-in-days":320,"URL":"http:\/\/www.elsevier.com\/open-access\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2024,8,1]],"date-time":"2024-08-01T00:00:00Z","timestamp":1722470400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["The Veterinary Journal"],"published-print":{"date-parts":[[2024,8]]},"DOI":"10.1016\/j.tvjl.2024.106151","type":"journal-article","created":{"date-parts":[[2024,5,29]],"date-time":"2024-05-29T23:23:42Z","timestamp":1717025022000},"page":"106151","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":3,"special_numbering":"C","title":["Urinary steroid profiling using liquid chromatography-tandem mass spectrometry for the diagnosis of canine Cushing\u2019s syndrome"],"prefix":"10.1016","volume":"306","author":[{"given":"N.","family":"Nagata","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Sawamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Y.","family":"Ikenaka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Morishita","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Hosoya","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"N.","family":"Sasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M.","family":"Takiguchi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.tvjl.2024.106151_bib1","doi-asserted-by":"crossref","DOI":"10.1016\/j.beem.2021.101488","article-title":"Steroid profiling in the diagnosis of mild and overt Cushing\u2019s syndrome","volume":"35","author":"Athimulam","year":"2021","journal-title":"Best Practice Research Clinical Endocrinology Metabolism"},{"key":"10.1016\/j.tvjl.2024.106151_bib2","doi-asserted-by":"crossref","first-page":"1292","DOI":"10.1111\/jvim.12192","article-title":"Diagnosis of spontaneous canine hyperadrenocorticism: 2012 ACVIM consensus statement (small animal)","volume":"27","author":"Behrend","year":"2013","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"10.1016\/j.tvjl.2024.106151_bib3","doi-asserted-by":"crossref","first-page":"1662","DOI":"10.2460\/javma.2005.226.1662","article-title":"Corticosterone- and aldosterone-secreting adrenocortical tumor in a dog","volume":"226","author":"Behrend","year":"2005","journal-title":"Journal of American Veterinary Medical Association"},{"key":"10.1016\/j.tvjl.2024.106151_bib4","doi-asserted-by":"crossref","DOI":"10.1016\/j.tvjl.2019.105343","article-title":"Diagnosis of spontaneous hyperadrenocorticism in dogs. Part 2: Adrenal function testing and differentiating tests","volume":"252","author":"Bennaim","year":"2019","journal-title":"The Veterinary Journal"},{"key":"10.1016\/j.tvjl.2024.106151_bib5","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1111\/vcp.12006","article-title":"ASVCP reference interval guidelines: determination of de novo reference intervals in veterinary species and other related topics","volume":"41","author":"Friedrichs","year":"2012","journal-title":"Veterinary Clinical Pathology"},{"key":"10.1016\/j.tvjl.2024.106151_bib6","doi-asserted-by":"crossref","first-page":"1433","DOI":"10.1111\/jvim.12399","article-title":"Urinary corticoid concentrations measured by 5 different immunoassays and gas chromatography-mass spectrometry in healthy dogs and dogs with hypercortisolism at home and in the hospital","volume":"28","author":"Galeandro","year":"2014","journal-title":"Journal of Veterinary Internal Medicine"},{"key":"10.1016\/j.tvjl.2024.106151_bib7","doi-asserted-by":"crossref","DOI":"10.3389\/fendo.2023.1158573","article-title":"Distinct serum steroid profiles between adrenal Cushing syndrome and Cushing disease","volume":"14","author":"Gao","year":"2023","journal-title":"Frontiers in Endocrinology"},{"key":"10.1016\/j.tvjl.2024.106151_bib8","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1111\/j.1939-165X.2011.00287.x","article-title":"Reference Value Advisor: a new freeware set of macroinstructions to calculate reference intervals with Microsoft Excel","volume":"40","author":"Geffr\u00e9","year":"2011","journal-title":"Veterinary Clinical Pathology"},{"key":"10.1016\/j.tvjl.2024.106151_bib9","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1111\/vcp.12301","article-title":"Liquid chromatography-tandem mass spectrometry (LC\/MS\/MS) for analysis of endogenous steroids in the luteal phase and early pregnancy in dogs: a pilot study","volume":"44","author":"Holst","year":"2015","journal-title":"Veterinary Clinical Pathology"},{"key":"10.1016\/j.tvjl.2024.106151_bib10","doi-asserted-by":"crossref","first-page":"99","DOI":"10.1111\/j.1748-5827.1997.tb03327.x","article-title":"Evaluation of the urinary cortisol: creatinine ratio in the diagnosis of hyperadrenocorticism in dogs","volume":"38","author":"Jensen","year":"1997","journal-title":"Journal of Small Animal Practice"},{"key":"10.1016\/j.tvjl.2024.106151_bib11","doi-asserted-by":"crossref","first-page":"21","DOI":"10.1053\/j.tcam.2012.06.001","article-title":"Recent advances in the diagnosis of Cushing\u2019s syndrome in dogs","volume":"27","author":"Kooistra","year":"2012","journal-title":"Topics in Companion Animal Medicine"},{"key":"10.1016\/j.tvjl.2024.106151_bib12","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1292\/jvms.22-0131","article-title":"Urinary corticoid to creatinine ratios using IMMULITE 2000 XPi for diagnosis of canine hypercortisolism","volume":"84","author":"Nagata","year":"2022","journal-title":"The Journal of Veterinary Medical Science"},{"key":"10.1016\/j.tvjl.2024.106151_bib13","doi-asserted-by":"crossref","first-page":"63","DOI":"10.1016\/0960-0760(91)90168-5","article-title":"Age-related changes in the dog hypothalamic-pituitary-adrenocortical system: neuroendocrine activity and corticosteroid receptors","volume":"40","author":"Reul","year":"1991","journal-title":"The Journal of Steroid Biochemistry and Molecular Biology"},{"key":"10.1016\/j.tvjl.2024.106151_bib14","doi-asserted-by":"crossref","first-page":"648","DOI":"10.1292\/jvms.20-0508","article-title":"Urinary free metanephrines measurement in dogs with adrenal gland diseases using a new simple liquid chromatography tandem mass spectrometry method","volume":"83","author":"Sasaki","year":"2021","journal-title":"The Journal of Veterinary Medical Science"},{"key":"10.1016\/j.tvjl.2024.106151_bib15","doi-asserted-by":"crossref","first-page":"1634","DOI":"10.1292\/jvms.21-0406","article-title":"Simultaneous steroids measurement in dogs with hyperadrenocorticism using a column-switching liquid chromatography-tandem mass spectrometry method","volume":"83","author":"Sasaki","year":"2021","journal-title":"The Journal of Veterinary Medical Science"},{"key":"10.1016\/j.tvjl.2024.106151_bib16","doi-asserted-by":"crossref","first-page":"997","DOI":"10.1136\/vr.c4010","article-title":"Tailored reference limits for urine corticoid:creatinine ratio in dogs to answer distinct clinical questions","volume":"167","author":"Zeugswetter","year":"2010","journal-title":"Veterinary Record"}],"container-title":["The Veterinary Journal"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109002332400090X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S109002332400090X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2024,8,14]],"date-time":"2024-08-14T11:25:01Z","timestamp":1723634701000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S109002332400090X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,8]]},"references-count":16,"alternative-id":["S109002332400090X"],"URL":"https:\/\/doi.org\/10.1016\/j.tvjl.2024.106151","relation":{},"ISSN":["1090-0233"],"issn-type":[{"value":"1090-0233","type":"print"}],"subject":[],"published":{"date-parts":[[2024,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Urinary steroid profiling using liquid chromatography-tandem mass spectrometry for the diagnosis of canine Cushing\u2019s syndrome","name":"articletitle","label":"Article Title"},{"value":"The Veterinary Journal","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tvjl.2024.106151","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 Elsevier Ltd. All rights are reserved, including those for text and data mining, AI training, and similar technologies.","name":"copyright","label":"Copyright"}],"article-number":"106151"}}