{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,27]],"date-time":"2026-10-27T23:33:55Z","timestamp":1793144035131,"version":"4.5.0"},"reference-count":138,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2025,6,1]],"date-time":"2025-06-01T00:00:00Z","timestamp":1748736000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,12,15]],"date-time":"2024-12-15T00:00:00Z","timestamp":1734220800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Tumour Virus Research"],"published-print":{"date-parts":[[2025,6]]},"DOI":"10.1016\/j.tvr.2024.200308","type":"journal-article","created":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T03:17:08Z","timestamp":1734319028000},"page":"200308","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":26,"special_numbering":"C","title":["Clinical indications for host-cell DNA methylation markers in cervical screening and management of cervical intraepithelial neoplasia: A review"],"prefix":"10.1016","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-5548-4557","authenticated-orcid":false,"given":"S.","family":"Dick","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"D.A.M.","family":"Heideman","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J.","family":"Berkhof","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.D.M.","family":"Steenbergen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9610-8064","authenticated-orcid":false,"given":"M.C.G.","family":"Bleeker","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"issue":"9916","key":"10.1016\/j.tvr.2024.200308_bib1","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/S0140-6736(13)62218-7","article-title":"Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials","volume":"383","author":"Ronco","year":"2014","journal-title":"Lancet (London, England)"},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib2","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/j.ygyno.2014.11.076","article-title":"Primary cervical cancer screening with human papillomavirus: end of study results from the ATHENA study using HPV as the first-line screening test","volume":"136","author":"Wright","year":"2015","journal-title":"Gynecol. Oncol."},{"issue":"3","key":"10.1016\/j.tvr.2024.200308_bib3","doi-asserted-by":"crossref","first-page":"602","DOI":"10.1002\/ijc.26056","article-title":"Evaluation of 14 triage strategies for HPV DNA-positive women in population-based cervical screening","volume":"130","author":"Rijkaart","year":"2012","journal-title":"Int. J. Cancer"},{"key":"10.1016\/j.tvr.2024.200308_bib4","doi-asserted-by":"crossref","first-page":"108","DOI":"10.1016\/j.ypmed.2018.12.021","article-title":"HPV-based cervical screening: rationale, expectations and future perspectives of the new Dutch screening programme","volume":"119","author":"Polman","year":"2019","journal-title":"Prev. Med."},{"issue":"11","key":"10.1016\/j.tvr.2024.200308_bib5","doi-asserted-by":"crossref","first-page":"1650","DOI":"10.1038\/sj.onc.1209950","article-title":"Viral oncoproteins target the DNA methyltransferases","volume":"26","author":"Burgers","year":"2007","journal-title":"Oncogene"},{"issue":"7","key":"10.1016\/j.tvr.2024.200308_bib6","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1080\/15592294.2018.1507197","article-title":"Host-cell DNA methylation patterns during high-risk HPV-induced carcinogenesis reveal a heterogeneous nature of cervical pre-cancer","volume":"13","author":"Verlaat","year":"2018","journal-title":"Epigenetics"},{"key":"10.1016\/j.tvr.2024.200308_bib7","doi-asserted-by":"crossref","first-page":"36","DOI":"10.1016\/j.mrrev.2016.09.006","article-title":"Human papillomaviruses in epigenetic regulations","volume":"772","author":"Durzynska","year":"2017","journal-title":"Mutat. Res. Rev. Mutat. Res."},{"issue":"6","key":"10.1016\/j.tvr.2024.200308_bib8","doi-asserted-by":"crossref","first-page":"395","DOI":"10.1038\/nrc3728","article-title":"Clinical implications of (epi)genetic changes in HPV-induced cervical precancerous lesions","volume":"14","author":"Steenbergen","year":"2014","journal-title":"Nat. Rev. Cancer"},{"issue":"4","key":"10.1016\/j.tvr.2024.200308_bib9","doi-asserted-by":"crossref","first-page":"294","DOI":"10.1093\/jnci\/djh031","article-title":"TSLC1 gene silencing in cervical cancer cell lines and cervical neoplasia","volume":"96","author":"Steenbergen","year":"2004","journal-title":"J. Natl. Cancer Inst."},{"issue":"10","key":"10.1016\/j.tvr.2024.200308_bib10","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1002\/gcc.20590","article-title":"Integrated genomic and transcriptional profiling identifies chromosomal loci with altered gene expression in cervical cancer","volume":"47","author":"Wilting","year":"2008","journal-title":"Genes Chromosomes Cancer"},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib11","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1002\/path.4210","article-title":"Methylation-specific digital karyotyping of HPV16E6E7-expressing human keratinocytes identifies novel methylation events in cervical carcinogenesis","volume":"231","author":"Steenbergen","year":"2013","journal-title":"J. Pathol."},{"key":"10.1016\/j.tvr.2024.200308_bib12","doi-asserted-by":"crossref","first-page":"167","DOI":"10.1186\/1476-4598-9-167","article-title":"Methylation-mediated silencing and tumour suppressive function of hsa-miR-124 in cervical cancer","volume":"9","author":"Wilting","year":"2010","journal-title":"Mol. Cancer"},{"issue":"3","key":"10.1016\/j.tvr.2024.200308_bib13","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0091905","article-title":"A promising DNA methylation signature for the triage of high-risk human papillomavirus DNA-positive women","volume":"9","author":"Hansel","year":"2014","journal-title":"PLoS One"},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib14","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1002\/ijc.23519","article-title":"Identification of novel DNA methylation markers in cervical cancer","volume":"123","author":"Lai","year":"2008","journal-title":"Int. J. Cancer"},{"issue":"49","key":"10.1016\/j.tvr.2024.200308_bib15","doi-asserted-by":"crossref","first-page":"80735","DOI":"10.18632\/oncotarget.12598","article-title":"Genome-wide methylome analysis using MethylCap-seq uncovers 4 hypermethylated markers with high sensitivity for both adeno- and squamous-cell cervical carcinoma","volume":"7","author":"Wang","year":"2016","journal-title":"Oncotarget"},{"issue":"14","key":"10.1016\/j.tvr.2024.200308_bib16","doi-asserted-by":"crossref","first-page":"3456","DOI":"10.1158\/1078-0432.CCR-17-3615","article-title":"Identification and validation of a 3-gene methylation classifier for HPV-based cervical screening on self-samples","volume":"24","author":"Verlaat","year":"2018","journal-title":"Clin. Cancer Res."},{"issue":"14","key":"10.1016\/j.tvr.2024.200308_bib17","doi-asserted-by":"crossref","first-page":"3813","DOI":"10.1158\/1078-0432.CCR-16-2641","article-title":"Genome-wide DNA methylation profiling reveals methylation markers associated with 3q gain for detection of cervical precancer and cancer","volume":"23","author":"Verlaat","year":"2017","journal-title":"Clin. Cancer Res. : An Off. J. American Assoc. Cancer Res."},{"issue":"8","key":"10.1016\/j.tvr.2024.200308_bib18","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1002\/ijc.26326","article-title":"A four-gene methylation marker panel as triage test in high-risk human papillomavirus positive patients","volume":"130","author":"Eijsink","year":"2012","journal-title":"Int. J. Cancer"},{"issue":"8","key":"10.1016\/j.tvr.2024.200308_bib19","doi-asserted-by":"crossref","first-page":"2661","DOI":"10.1158\/0008-5472.CAN-07-5913","article-title":"Genome-wide promoter analysis uncovers portions of the cancer methylome","volume":"68","author":"Hoque","year":"2008","journal-title":"Cancer Res."},{"key":"10.1016\/j.tvr.2024.200308_bib20","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1186\/s13148-016-0196-3","article-title":"Discovery of new methylation markers to improve screening for cervical intraepithelial neoplasia grade 2\/3","volume":"8","author":"Boers","year":"2016","journal-title":"Clin. Epigenet."},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib21","doi-asserted-by":"crossref","first-page":"116","DOI":"10.1186\/s13073-022-01116-9","article-title":"The WID-CIN test identifies women with, and at risk of, cervical intraepithelial neoplasia grade 3 and invasive cervical cancer","volume":"14","author":"Barrett","year":"2022","journal-title":"Genome Med."},{"issue":"5","key":"10.1016\/j.tvr.2024.200308_bib22","doi-asserted-by":"crossref","first-page":"1264","DOI":"10.1002\/ijc.32880","article-title":"Genome-wide DNA methylation profiling identifies two novel genes in cervical neoplasia","volume":"147","author":"El-Zein","year":"2020","journal-title":"Int. J. Cancer"},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib23","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1002\/ijc.28658","article-title":"Methylomics analysis identifies epigenetically silenced genes and implies an activation of \u03b2-catenin signaling in cervical cancer","volume":"135","author":"Chen","year":"2014","journal-title":"Int. J. Cancer"},{"issue":"7","key":"10.1016\/j.tvr.2024.200308_bib24","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0041060","article-title":"Methylomic analysis identifies frequent DNA methylation of zinc finger protein 582 (ZNF582) in cervical neoplasms","volume":"7","author":"Huang","year":"2012","journal-title":"PLoS One"},{"issue":"9","key":"10.1016\/j.tvr.2024.200308_bib25","doi-asserted-by":"crossref","DOI":"10.3390\/v15091802","article-title":"Efficiency of CIN2+ detection by thyrotropin-releasing hormone (TRH) site-specific methylation","volume":"15","author":"Chaiwongkot","year":"2023","journal-title":"Viruses"},{"issue":"4","key":"10.1016\/j.tvr.2024.200308_bib26","doi-asserted-by":"crossref","first-page":"1215","DOI":"10.1002\/ijc.32614","article-title":"FAM19A4\/miR124-2 methylation in invasive cervical cancer: a retrospective cross-sectional worldwide study","volume":"147","author":"Vink","year":"2020","journal-title":"Int. J. Cancer"},{"issue":"12","key":"10.1016\/j.tvr.2024.200308_bib27","doi-asserted-by":"crossref","first-page":"1067","DOI":"10.1136\/jclinpath-2014-202616","article-title":"CADM1, MAL and miR124-2 methylation analysis in cervical scrapes to detect cervical and endometrial cancer","volume":"67","author":"De Strooper","year":"2014","journal-title":"J. Clin. Pathol."},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib28","doi-asserted-by":"crossref","first-page":"1182","DOI":"10.1186\/s12885-018-4877-5","article-title":"The clinical significance of FAM19A4 methylation in high-risk HPV-positive cervical samples for the detection of cervical (pre)cancer in Chinese women","volume":"18","author":"Bu","year":"2018","journal-title":"BMC Cancer"},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib29","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1186\/s12885-023-10628-5","article-title":"Promoter hypermethylation analysis of host genes in cervical intraepithelial neoplasia and cervical cancers on histological cervical specimens","volume":"23","author":"Shi","year":"2023","journal-title":"BMC Cancer"},{"issue":"18","key":"10.1016\/j.tvr.2024.200308_bib30","doi-asserted-by":"crossref","first-page":"1569","DOI":"10.2217\/epi-2019-0331","article-title":"Evaluation of six methylation markers derived from genome-wide screens for detection of cervical precancer and cancer","volume":"12","author":"Dick","year":"2020","journal-title":"Epigenomics"},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib31","first-page":"1674","article-title":"Assessing methylation status of PAX1 in cervical scrapings, as a novel diagnostic and predictive biomarker, was closely related to screen cervical cancer","volume":"8","author":"Xu","year":"2015","journal-title":"Int. J. Clin. Exp. Pathol."},{"issue":"12","key":"10.1016\/j.tvr.2024.200308_bib32","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1158\/1940-6207.CAPR-14-0237","article-title":"Methylation analysis of the FAM19A4 gene in cervical scrapes is highly efficient in detecting cervical carcinomas and advanced CIN2\/3 lesions","volume":"7","author":"De","year":"2014","journal-title":"Cancer Prev. Res."},{"key":"10.1016\/j.tvr.2024.200308_bib33","doi-asserted-by":"crossref","first-page":"66","DOI":"10.1186\/s13148-016-0232-3","article-title":"Combined clinical and genetic testing algorithm for cervical cancer diagnosis","volume":"8","author":"Liou","year":"2016","journal-title":"Clin. Epigenet."},{"issue":"4","key":"10.1016\/j.tvr.2024.200308_bib34","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1111\/IGC.0b013e3181c7fe6e","article-title":"Quantitative analysis of methylation status of the PAX1 gene for detection of cervical cancer","volume":"20","author":"Huang","year":"2010","journal-title":"Int. J. Gynecol. Cancer : Off. J. Int. Gynecol. Cancer Soc."},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib35","doi-asserted-by":"crossref","first-page":"1197","DOI":"10.1186\/s12885-018-5125-8","article-title":"Performance of a DNA methylation marker panel using liquid-based cervical scrapes to detect cervical cancer and its precancerous stages","volume":"18","author":"Schmitz","year":"2018","journal-title":"BMC Cancer"},{"key":"10.1016\/j.tvr.2024.200308_bib36","doi-asserted-by":"crossref","first-page":"118","DOI":"10.1186\/s13148-017-0419-2","article-title":"Performance of a methylation specific real-time PCR assay as a triage test for HPV-positive women","volume":"9","author":"Schmitz","year":"2017","journal-title":"Clin. Epigenet."},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib37","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ygyno.2015.01.550","article-title":"Follow-up of high-risk HPV positive women by combined cytology and bi-marker CADM1\/MAL methylation analysis on cervical scrapes","volume":"137","author":"Verhoef","year":"2015","journal-title":"Gynecol. Oncol."},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib38","doi-asserted-by":"crossref","first-page":"160","DOI":"10.1002\/ijc.31787","article-title":"Reliable identification of women with CIN3+ using hrHPV genotyping and methylation markers in a cytology-screened referral population","volume":"144","author":"Leeman","year":"2019","journal-title":"Int. J. Cancer"},{"issue":"37","key":"10.1016\/j.tvr.2024.200308_bib39","doi-asserted-by":"crossref","first-page":"62274","DOI":"10.18632\/oncotarget.19459","article-title":"Utility of gene methylation analysis, cytological examination, and HPV-16\/18 genotyping in triage of high-risk human papilloma virus-positive women","volume":"8","author":"Tian","year":"2017","journal-title":"Oncotarget"},{"issue":"6","key":"10.1016\/j.tvr.2024.200308_bib40","doi-asserted-by":"crossref","first-page":"1541","DOI":"10.1002\/ijc.31539","article-title":"Cervical cancer risk in HPV-positive women after a negative FAM19A4\/mir124-2 methylation test: a post hoc analysis in the POBASCAM trial with 14 year follow-up","volume":"143","author":"De Strooper","year":"2018","journal-title":"Int. J. Cancer"},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib41","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/j.cmi.2020.03.018","article-title":"FAM19A4\/miR124-2 methylation analysis as a triage test for HPV-positive women: cross-sectional and longitudinal data from a Dutch screening cohort","volume":"27","author":"Vink","year":"2021","journal-title":"Clin. Microbiol. Infection : Off. Pub.European Soc. Clin. Microbiol. Infect. Dis."},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib42","doi-asserted-by":"crossref","first-page":"396","DOI":"10.1002\/ijc.33320","article-title":"Methylation markers FAM19A4 and miR124-2 as triage strategy for primary human papillomavirus screen positive women: a large European multicenter study","volume":"148","author":"Bonde","year":"2021","journal-title":"Int. J. Cancer"},{"issue":"7","key":"10.1016\/j.tvr.2024.200308_bib43","doi-asserted-by":"crossref","first-page":"1768","DOI":"10.1002\/ijc.33430","article-title":"DNA methylation markers as triage test for the early identification of cervical lesions in a Chinese population","volume":"148","author":"Li","year":"2021","journal-title":"Int. J. Cancer"},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib44","doi-asserted-by":"crossref","first-page":"283","DOI":"10.1007\/s12094-020-02416-5","article-title":"The application value of PAX1 and ZNF582 gene methylation in high grade intraepithelial lesion and cervical cancer","volume":"23","author":"Liang","year":"2021","journal-title":"Clin. Transl. Oncol."},{"issue":"8","key":"10.1016\/j.tvr.2024.200308_bib45","doi-asserted-by":"crossref","first-page":"2720","DOI":"10.1111\/jog.14869","article-title":"The application of PAX1 methylation detection and HPV E6\/E7 mRNA detection in cervical cancer screening","volume":"47","author":"Li","year":"2021","journal-title":"J. Obstet. Gynaecol. Res."},{"key":"10.1016\/j.tvr.2024.200308_bib46","doi-asserted-by":"crossref","DOI":"10.3389\/fonc.2021.560296","article-title":"Promoter hypermethylation analysis of host genes in cervical cancer patients with and without human immunodeficiency virus in Botswana","volume":"11","author":"Tawe","year":"2021","journal-title":"Front. Oncol."},{"issue":"7","key":"10.1016\/j.tvr.2024.200308_bib47","doi-asserted-by":"crossref","first-page":"769","DOI":"10.1080\/15592294.2018.1507197","article-title":"Host-cell DNA methylation patterns during high-risk HPV-induced carcinogenesis reveal a heterogeneous nature of cervical pre-cancer","volume":"13","author":"Verlaat","year":"2018","journal-title":"Epigenetics"},{"issue":"12","key":"10.1016\/j.tvr.2024.200308_bib48","doi-asserted-by":"crossref","first-page":"1251","DOI":"10.1158\/1940-6207.CAPR-14-0237","article-title":"Methylation analysis of the FAM19A4 gene in cervical scrapes is highly efficient in detecting cervical carcinomas and advanced CIN2\/3 lesions","volume":"7","author":"De","year":"2014","journal-title":"Cancer Prev Res (Phila)"},{"issue":"6","key":"10.1016\/j.tvr.2024.200308_bib49","doi-asserted-by":"crossref","first-page":"1293","DOI":"10.1002\/ijc.28138","article-title":"CADM1 and MAL promoter methylation levels in hrHPV-positive cervical scrapes increase proportional to degree and duration of underlying cervical disease","volume":"133","author":"Bierkens","year":"2013","journal-title":"Int. J. Cancer"},{"issue":"3","key":"10.1016\/j.tvr.2024.200308_bib50","doi-asserted-by":"crossref","first-page":"e827","DOI":"10.1093\/cid\/ciac433","article-title":"FAM19A4\/miR124-2 methylation testing and human papillomavirus (HPV) 16\/18 genotyping in HPV-positive women under the age of 30 years","volume":"76","author":"Vink","year":"2023","journal-title":"Clin. Infect. Dis. : An Off. Pub. Infect. Dis. Soc. America"},{"issue":"4","key":"10.1016\/j.tvr.2024.200308_bib51","doi-asserted-by":"crossref","first-page":"992","DOI":"10.1002\/ijc.29824","article-title":"Comparing the performance of FAM19A4 methylation analysis, cytology and HPV16\/18 genotyping for the detection of cervical (pre)cancer in high-risk HPV-positive women of a gynecologic outpatient population (COMETH study)","volume":"138","author":"Luttmer","year":"2016","journal-title":"Int. J. Cancer"},{"issue":"3","key":"10.1016\/j.tvr.2024.200308_bib52","doi-asserted-by":"crossref","first-page":"168","DOI":"10.1002\/gcc.22818","article-title":"Combined assessment of 3q26 amplification and promoter methylation in patients with high grade cervical lesions show age specific differences","volume":"59","author":"Beiersdorf","year":"2020","journal-title":"Genes Chromosomes Cancer"},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib53","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1186\/s13148-022-01353-0","article-title":"DNA methylation-based detection and prediction of cervical intraepithelial neoplasia grade 3 and invasive cervical cancer with the WID\u2122-qCIN test","volume":"14","author":"Herzog","year":"2022","journal-title":"Clin. Epigenet."},{"key":"10.1016\/j.tvr.2024.200308_bib54","doi-asserted-by":"crossref","first-page":"k499","DOI":"10.1136\/bmj.k499","article-title":"Clinical course of untreated cervical intraepithelial neoplasia grade 2 under active surveillance: systematic review and meta-analysis","volume":"360","author":"Tainio","year":"2018","journal-title":"BMJ (Clinical research ed)"},{"issue":"3","key":"10.1016\/j.tvr.2024.200308_bib55","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1097\/LGT.0000000000000604","article-title":"The natural history of cervical intraepithelial neoplasia grades 1, 2, and 3: a systematic review and meta-analysis","volume":"25","author":"Loopik","year":"2021","journal-title":"J. Low. Genit. Tract Dis."},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib56","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1002\/ijc.29706","article-title":"CADM1 and MAL methylation status in cervical scrapes is representative of the most severe underlying lesion in women with multiple cervical biopsies","volume":"138","author":"Van Baars","year":"2016","journal-title":"Int. J. Cancer"},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib57","doi-asserted-by":"crossref","first-page":"171","DOI":"10.1186\/s13148-020-00963-w","article-title":"Triage of hrHPV-positive women: comparison of two commercial methylation-specific PCR assays","volume":"12","author":"Dippmann","year":"2020","journal-title":"Clin. Epigenet."},{"issue":"9","key":"10.1016\/j.tvr.2024.200308_bib58","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0274825","article-title":"Full genotyping and FAM19A4\/miR124-2 methylation analysis in high-risk human papillomavirus-positive samples from women over 30 years participating in cervical cancer screening in \u00d6rebro, Sweden","volume":"17","author":"Kaliff","year":"2022","journal-title":"PLoS One"},{"issue":"3","key":"10.1016\/j.tvr.2024.200308_bib59","doi-asserted-by":"crossref","first-page":"204","DOI":"10.1111\/cyt.13213","article-title":"Prediction of cervical cancer precursor lesions by quantitative methylation specific PCR: a retrospective study","volume":"34","author":"Al Roomy","year":"2023","journal-title":"Cytopathology : Off. J. British Soc. Clinical Cytology."},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib60","doi-asserted-by":"crossref","DOI":"10.1371\/journal.pone.0210289","article-title":"Role of genomic DNA methylation in detection of cytologic and histologic abnormalities in high risk HPV-infected women","volume":"14","author":"Dankai","year":"2019","journal-title":"PLoS One"},{"issue":"5","key":"10.1016\/j.tvr.2024.200308_bib61","doi-asserted-by":"crossref","first-page":"1119","DOI":"10.1002\/ijc.30534","article-title":"Performance of a new HPV and biomarker assay in the management of hrHPV positive women: subanalysis of the ongoing multicenter TRACE clinical trial (n > 6,000) to evaluate POU4F3 methylation as a potential biomarker of cervical precancer and cancer","volume":"140","author":"Kocsis","year":"2017","journal-title":"Int. J. Cancer"},{"issue":"3","key":"10.1016\/j.tvr.2024.200308_bib62","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1002\/ijc.33820","article-title":"Performance of DNA methylation analysis of ASCL1, LHX8, ST6GALNAC5, GHSR, ZIC1 and SST for the triage of HPV-positive women: results from a Dutch primary HPV-based screening cohort","volume":"150","author":"Verhoef","year":"2022","journal-title":"Int. J. Cancer"},{"issue":"9","key":"10.1016\/j.tvr.2024.200308_bib63","doi-asserted-by":"crossref","first-page":"2218","DOI":"10.1002\/ijc.25890","article-title":"Combined CADM1 and MAL promoter methylation analysis to detect (pre-)malignant cervical lesions in high-risk HPV-positive women","volume":"129","author":"Overmeer","year":"2011","journal-title":"Int. J. Cancer"},{"issue":"9","key":"10.1016\/j.tvr.2024.200308_bib64","doi-asserted-by":"crossref","first-page":"1933","DOI":"10.1158\/1055-9965.EPI-14-0347","article-title":"Combined CADM1\/MAL methylation and cytology testing for colposcopy triage of high-risk HPV-positive women","volume":"23","author":"De","year":"2014","journal-title":"Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology"},{"issue":"8","key":"10.1016\/j.tvr.2024.200308_bib65","doi-asserted-by":"crossref","first-page":"2459","DOI":"10.1158\/1078-0432.CCR-10-2548","article-title":"Combined promoter methylation analysis of CADM1 and MAL: an objective triage tool for high-risk human papillomavirus DNA-positive women","volume":"17","author":"Hesselink","year":"2011","journal-title":"Clin. Cancer Res. : An Off. J. American Assoc. Cancer Res."},{"issue":"6","key":"10.1016\/j.tvr.2024.200308_bib66","doi-asserted-by":"crossref","DOI":"10.1097\/MD.0000000000014297","article-title":"ZNF582 methylation as a potential biomarker to predict cervical intraepithelial neoplasia type III\/worse: a meta-analysis of related studies in Chinese population","volume":"98","author":"Li","year":"2019","journal-title":"Medicine (Baltimore)"},{"issue":"23","key":"10.1016\/j.tvr.2024.200308_bib67","doi-asserted-by":"crossref","first-page":"2583","DOI":"10.2217\/fon-2021-1625","article-title":"Methylated ZNF582 as a triage marker for occult cervical cancer and advanced cervical intraepithelial neoplasia","volume":"18","author":"Su","year":"2022","journal-title":"Future Oncol."},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib68","doi-asserted-by":"crossref","first-page":"429","DOI":"10.1016\/j.ygyno.2021.02.011","article-title":"DNA methylation marker for the triage of hrHPV positive women in cervical cancer screening: real-world evidence in Taiwan","volume":"161","author":"Chang","year":"2021","journal-title":"Gynecol. Oncol."},{"issue":"8","key":"10.1016\/j.tvr.2024.200308_bib69","article-title":"ZNF671 methylation test in cervical scrapings for cervical intraepithelial neoplasia grade 3 and cervical cancer detection","volume":"4","author":"Zhu","year":"2023","journal-title":"Cell Rep Med"},{"issue":"28","key":"10.1016\/j.tvr.2024.200308_bib70","doi-asserted-by":"crossref","first-page":"1917","DOI":"10.2217\/fon-2023-0226","article-title":"Utilization of PAX1 methylation test for cervical cancer screening of non-HPV16\/18 high-risk HPV infection in women","volume":"19","author":"Yang","year":"2023","journal-title":"Future Oncol."},{"issue":"4","key":"10.1016\/j.tvr.2024.200308_bib71","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1002\/ijc.31897","article-title":"DNA methylation markers as a triage test for identification of cervical lesions in a high risk human papillomavirus positive screening cohort","volume":"144","author":"Van Leeuwen","year":"2019","journal-title":"Int. J. Cancer"},{"issue":"8","key":"10.1016\/j.tvr.2024.200308_bib72","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1038\/s41591-024-03014-6","article-title":"Cervical cancer screening using DNA methylation triage in a real-world population","volume":"30","author":"Schreiberhuber","year":"2024","journal-title":"Nat. Med."},{"issue":"11","key":"10.1016\/j.tvr.2024.200308_bib73","doi-asserted-by":"crossref","first-page":"954","DOI":"10.1038\/s41416-019-0593-4","article-title":"Performance of DNA methylation assays for detection of high-grade cervical intraepithelial neoplasia (CIN2+): a systematic review and meta-analysis","volume":"121","author":"Kelly","year":"2019","journal-title":"Br. J. Cancer"},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib74","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1186\/s13148-023-01537-2","article-title":"DNA methylation as a triage marker for colposcopy referral in HPV-based cervical cancer screening: a systematic review and meta-analysis","volume":"15","author":"Salta","year":"2023","journal-title":"Clin. Epigenet."},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib75","doi-asserted-by":"crossref","first-page":"368","DOI":"10.1016\/j.ygyno.2019.06.002","article-title":"Long-term CIN3+ risk of HPV positive women after triage with FAM19A4\/miR124-2 methylation analysis","volume":"154","author":"Dick","year":"2019","journal-title":"Gynecol. Oncol."},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib76","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1111\/aogs.14707","article-title":"Cervix cytology samples revealed increased methylation of the human markers FAM19A4\/miR124-2 up to 8 years before adenocarcinoma","volume":"103","author":"Lindroth","year":"2024","journal-title":"Acta Obstet. Gynecol. Scand."},{"issue":"24","key":"10.1016\/j.tvr.2024.200308_bib77","article-title":"Comparing the costs and diagnostic outcomes of replacing cytology with the QIAsure DNA methylation test as a triage within HPV primary cervical cancer screening in The Netherlands","volume":"13","author":"Puri Sudhir","year":"2023","journal-title":"Diagnostics (Basel)"},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib78","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1111\/cyt.12652","article-title":"Implementation of HPV-based cervical cancer screening in an organised regional screening programme: 3 years of experience","volume":"30","author":"Veijalainen","year":"2019","journal-title":"Cytopathology : Off. J. British Soc. Clinical Cytology."},{"issue":"11","key":"10.1016\/j.tvr.2024.200308_bib79","doi-asserted-by":"crossref","first-page":"1365","DOI":"10.1111\/1471-0528.15893","article-title":"Five-year risk of CIN3 after short-term HPV-DNA negativity in cytology-negative women: a population-based cohort study","volume":"126","author":"Del Mistro","year":"2019","journal-title":"BJOG An Int. J. Obstet. Gynaecol."},{"issue":"5","key":"10.1016\/j.tvr.2024.200308_bib80","doi-asserted-by":"crossref","DOI":"10.1136\/bmjopen-2016-014788","article-title":"Randomised healthcare policy evaluation of organised primary human papillomavirus screening of women aged 56-60","volume":"7","author":"Lamin","year":"2017","journal-title":"BMJ Open"},{"key":"10.1016\/j.tvr.2024.200308_bib81","doi-asserted-by":"crossref","first-page":"l240","DOI":"10.1136\/bmj.l240","article-title":"Primary cervical screening with high risk human papillomavirus testing: observational study","volume":"364","author":"Rebolj","year":"2019","journal-title":"BMJ (Clinical research ed)"},{"key":"10.1016\/j.tvr.2024.200308_bib82","doi-asserted-by":"crossref","first-page":"203","DOI":"10.2147\/CLEP.S243546","article-title":"Clinical performance of human papillomavirus (HPV) testing versus cytology for cervical cancer screening: results of a large Danish implementation study","volume":"12","author":"Thomsen","year":"2020","journal-title":"Clin. Epidemiol."},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib83","doi-asserted-by":"crossref","first-page":"228","DOI":"10.1186\/s12916-019-1460-0","article-title":"Introduction of primary screening using high-risk HPV DNA detection in the Dutch cervical cancer screening programme: a population-based cohort study","volume":"17","author":"Aitken","year":"2019","journal-title":"BMC Med."},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib84","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.ajog.2020.08.026","article-title":"Benefit and burden in the Dutch cytology-based vs high-risk human papillomavirus-based cervical cancer screening program","volume":"224","author":"Loopik","year":"2021","journal-title":"Am. J. Obstet. Gynecol."},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib86","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1038\/s41416-021-01614-4","article-title":"Risk-stratification of HPV-positive women with low-grade cytology by FAM19A4\/miR124-2 methylation and HPV genotyping","volume":"126","author":"Dick","year":"2021","journal-title":"Br. J. Cancer"},{"issue":"14","key":"10.1016\/j.tvr.2024.200308_bib87","doi-asserted-by":"crossref","first-page":"1945","DOI":"10.1097\/QAD.0000000000001583","article-title":"Selection of women at risk for cervical cancer in an HIV-infected South African population","volume":"31","author":"Van Zummeren","year":"2017","journal-title":"AIDS"},{"issue":"3","key":"10.1016\/j.tvr.2024.200308_bib88","doi-asserted-by":"crossref","first-page":"311","DOI":"10.1097\/QAI.0000000000000744","article-title":"Methylation levels of CADM1, MAL, and mir124-2 in cervical scrapes for triage of HIV-infected, high-risk HPV-positive women in Kenya","volume":"70","author":"De Vuyst","year":"2015","journal-title":"J. Acquir. Immune Defic. Syndr."},{"issue":"13","key":"10.1016\/j.tvr.2024.200308_bib89","doi-asserted-by":"crossref","first-page":"2035","DOI":"10.1097\/QAD.0000000000002325","article-title":"The use of molecular markers for cervical screening of women living with HIV in South Africa","volume":"33","author":"Kremer","year":"2019","journal-title":"AIDS (London, England)"},{"issue":"15","key":"10.1016\/j.tvr.2024.200308_bib90","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1097\/QAD.0000000000001932","article-title":"Associations of human gene EPB41L3 DNA methylation and cervical intraepithelial neoplasia in women living with HIV-1 in Africa","volume":"32","author":"Kelly","year":"2018","journal-title":"AIDS (London, England)"},{"issue":"8","key":"10.1016\/j.tvr.2024.200308_bib91","doi-asserted-by":"crossref","DOI":"10.1002\/jia2.25165","article-title":"Detection of hypermethylated genes as markers for cervical screening in women living with HIV","volume":"21","author":"Kremer","year":"2018","journal-title":"J. Int. AIDS Soc."},{"issue":"3","key":"10.1016\/j.tvr.2024.200308_bib92","doi-asserted-by":"crossref","first-page":"416","DOI":"10.1093\/cid\/ciac801","article-title":"Validation of ASCL1 and LHX8 methylation analysis as primary cervical cancer screening strategy in South African women with human immunodeficiency virus","volume":"76","author":"Vink","year":"2023","journal-title":"Clin. Infect. Dis. : An Off. Pub. Infect. Dis. Soc. America"},{"key":"10.1016\/j.tvr.2024.200308_bib93","first-page":"g6192","article-title":"Fertility and early pregnancy outcomes after treatment for cervical intraepithelial neoplasia: systematic review and meta-analysis","volume":"349","author":"Kyrgiou","year":"2014","journal-title":"BMJ (Clinical research ed)"},{"key":"10.1016\/j.tvr.2024.200308_bib94","first-page":"i3633","article-title":"Adverse obstetric outcomes after local treatment for cervical preinvasive and early invasive disease according to cone depth: systematic review and meta-analysis","volume":"354","author":"Kyrgiou","year":"2016","journal-title":"BMJ (Clinical research ed)"},{"issue":"11","key":"10.1016\/j.tvr.2024.200308_bib96","doi-asserted-by":"crossref","first-page":"1500","DOI":"10.1001\/jama.285.11.1500","article-title":"Interobserver reproducibility of cervical cytologic and histologic interpretations: realistic estimates from the ASCUS-LSIL Triage Study","volume":"285","author":"Stoler","year":"2001","journal-title":"Jama"},{"issue":"5","key":"10.1016\/j.tvr.2024.200308_bib97","doi-asserted-by":"crossref","first-page":"805","DOI":"10.1309\/PT3PNC1QL2F4D2VL","article-title":"The relationship of community biopsy-diagnosed cervical intraepithelial neoplasia grade 2 to the quality control pathology-reviewed diagnoses: an ALTS report","volume":"127","author":"Castle","year":"2007","journal-title":"Am. J. Clin. Pathol."},{"issue":"6","key":"10.1016\/j.tvr.2024.200308_bib98","doi-asserted-by":"crossref","first-page":"729","DOI":"10.1097\/PAS.0000000000000381","article-title":"The interpretive variability of cervical biopsies and its relationship to HPV status","volume":"39","author":"Stoler","year":"2015","journal-title":"Am. J. Surg. Pathol."},{"issue":"3","key":"10.1016\/j.tvr.2024.200308_bib99","doi-asserted-by":"crossref","first-page":"424","DOI":"10.1016\/S0090-8258(03)00082-9","article-title":"Strength of correlations between colposcopic impression and biopsy histology","volume":"89","author":"Massad","year":"2003","journal-title":"Gynecol. Oncol."},{"issue":"12","key":"10.1016\/j.tvr.2024.200308_bib100","doi-asserted-by":"crossref","first-page":"1380","DOI":"10.1111\/j.1471-0528.1997.tb11007.x","article-title":"Observer variability among colposcopists from the West Midlands region","volume":"104","author":"Etherington","year":"1997","journal-title":"Br. J. Obstet. Gynaecol."},{"issue":"11","key":"10.1016\/j.tvr.2024.200308_bib101","doi-asserted-by":"crossref","first-page":"1518","DOI":"10.1097\/PAS.0000000000000498","article-title":"Investigating diagnostic problems of CIN1 and CIN2 associated with high-risk HPV by combining the novel molecular biomarker panHPVE4 with P16INK4a","volume":"39","author":"Van Baars","year":"2015","journal-title":"Am. J. Surg. Pathol."},{"issue":"4","key":"10.1016\/j.tvr.2024.200308_bib102","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1097\/pgp.0b013e31805152ab","article-title":"CIN2 is a much less reproducible and less valid diagnosis than CIN3: results from a histological review of population-based cervical samples","volume":"26","author":"Carreon","year":"2007","journal-title":"Int. J. Gynecol. Pathol. : official journal of the International Society of Gynecological Pathologists"},{"issue":"26","key":"10.1016\/j.tvr.2024.200308_bib103","doi-asserted-by":"crossref","first-page":"3037","DOI":"10.1200\/JCO.21.02433","article-title":"Clinical regression of high-grade cervical intraepithelial neoplasia is associated with absence of FAM19A4\/miR124-2 DNA methylation (CONCERVE study)","volume":"40","author":"Kremer","year":"2022","journal-title":"J. Clin. Oncol."},{"issue":"12","key":"10.1016\/j.tvr.2024.200308_bib104","doi-asserted-by":"crossref","first-page":"2582","DOI":"10.1093\/cid\/ciz677","article-title":"Methylation in predicting progression of untreated high-grade cervical intraepithelial neoplasia","volume":"70","author":"Louvanto","year":"2020","journal-title":"Clin. Infect. Dis. : An Off. Pub. Infect. Dis. Soc. America"},{"issue":"15","key":"10.1016\/j.tvr.2024.200308_bib105","doi-asserted-by":"crossref","DOI":"10.3390\/cancers15153951","article-title":"Evaluation of CIN2\/3 lesion regression in GynTect(\u00ae) DNA methylation-marker-negative patients in a longitudinal study","volume":"15","author":"Hoyer","year":"2023","journal-title":"Cancers (Basel)"},{"issue":"7","key":"10.1016\/j.tvr.2024.200308_bib106","doi-asserted-by":"crossref","DOI":"10.3390\/ijms24076479","article-title":"The role of methylation of host and\/or human papillomavirus (HPV) DNA in management of cervical intraepithelial neoplasia grade 2 (CIN2) lesions","volume":"24","author":"Dovnik","year":"2023","journal-title":"Int. J. Mol. Sci."},{"issue":"22","key":"10.1016\/j.tvr.2024.200308_bib107","doi-asserted-by":"crossref","first-page":"2542","DOI":"10.1200\/JCO.2016.71.4543","article-title":"Long-lasting increased risk of human papillomavirus-related carcinomas and premalignancies after cervical intraepithelial neoplasia grade 3: a population-based cohort study","volume":"35","author":"Ebisch","year":"2017","journal-title":"J. Clin. Oncol."},{"issue":"8","key":"10.1016\/j.tvr.2024.200308_bib108","doi-asserted-by":"crossref","first-page":"2048","DOI":"10.1002\/ijc.21604","article-title":"Long-term risk of invasive cervical cancer after treatment of squamous cervical intraepithelial neoplasia","volume":"118","author":"Soutter","year":"2006","journal-title":"Int. J. Cancer"},{"issue":"7629","key":"10.1016\/j.tvr.2024.200308_bib109","first-page":"1077","article-title":"Long term risk of invasive cancer after treatment for cervical intraepithelial neoplasia grade 3: population based cohort study","volume":"335","author":"Strander","year":"2007","journal-title":"BMJ (Clinical research ed)"},{"issue":"5","key":"10.1016\/j.tvr.2024.200308_bib110","doi-asserted-by":"crossref","first-page":"441","DOI":"10.1016\/S1470-2045(11)70078-X","article-title":"Risk of recurrent high-grade cervical intraepithelial neoplasia after successful treatment: a long-term multi-cohort study","volume":"12","author":"Kocken","year":"2011","journal-title":"Lancet Oncol."},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib111","doi-asserted-by":"crossref","first-page":"135","DOI":"10.1016\/j.ygyno.2016.07.089","article-title":"Performance of CADM1\/MAL-methylation analysis for monitoring of women treated for high-grade CIN","volume":"143","author":"Uijterwaal","year":"2016","journal-title":"Gynecol. Oncol."},{"issue":"12","key":"10.1016\/j.tvr.2024.200308_bib112","doi-asserted-by":"crossref","first-page":"2011","DOI":"10.1002\/ijc.34678","article-title":"Methylation testing for the detection of recurrent cervical intraepithelial neoplasia","volume":"153","author":"Dick","year":"2023","journal-title":"Int. J. Cancer"},{"issue":"7","key":"10.1016\/j.tvr.2024.200308_bib113","doi-asserted-by":"crossref","first-page":"953","DOI":"10.1097\/QAD.0000000000003197","article-title":"Posttreatment monitoring by ASCL1\/LHX8 methylation analysis in women with HIV treated for cervical intraepithelial neoplasia grade 2\/3","volume":"36","author":"Vink","year":"2022","journal-title":"AIDS (London, England)"},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib114","doi-asserted-by":"crossref","first-page":"31","DOI":"10.1186\/s13027-023-00510-1","article-title":"Molecular triage of cervical screening samples in women 55-59 years of age: a pilot study","volume":"18","author":"Helenius","year":"2023","journal-title":"Infect Agent Cancer"},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib115","doi-asserted-by":"crossref","first-page":"354","DOI":"10.1016\/j.ygyno.2019.05.024","article-title":"Age-specific HPV type distribution in high-grade cervical disease in screened and unvaccinated women","volume":"154","author":"Aro","year":"2019","journal-title":"Gynecol. Oncol."},{"issue":"18","key":"10.1016\/j.tvr.2024.200308_bib116","doi-asserted-by":"crossref","first-page":"1661","DOI":"10.2217\/epi-2020-0164","article-title":"DNA methylation markers for endometrial cancer detection in minimally invasive samples: a systematic review","volume":"12","author":"Van den Helder","year":"2020","journal-title":"Epigenomics"},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib117","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1002\/ijc.34504","article-title":"DNA methylation testing for endometrial cancer detection in urine, cervicovaginal self-samples and cervical scrapes","volume":"153","author":"Wever","year":"2023","journal-title":"Int. J. Cancer"},{"issue":"6","key":"10.1016\/j.tvr.2024.200308_bib118","doi-asserted-by":"crossref","first-page":"804","DOI":"10.1002\/ijc.2910630610","article-title":"Low efficiency of cytologic screening for cancer in situ of the cervix in older women","volume":"63","author":"Gustafsson","year":"1995","journal-title":"Int. J. Cancer"},{"issue":"6","key":"10.1016\/j.tvr.2024.200308_bib119","doi-asserted-by":"crossref","first-page":"575","DOI":"10.1159\/000353769","article-title":"Cytohistologic correlation in premenopausal and postmenopausal women","volume":"57","author":"Gilani","year":"2013","journal-title":"Acta Cytol."},{"issue":"4","key":"10.1016\/j.tvr.2024.200308_bib120","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1046\/j.1365-2303.1997.8382083.x","article-title":"The influence of the cervix on smear quality. I: atrophy. An audit of cervical smears taken post-colposcopic management of intraepithelial neoplasia","volume":"8","author":"Waddell","year":"1997","journal-title":"Cytopathology : official journal of the British Society for Clinical Cytology"},{"issue":"9","key":"10.1016\/j.tvr.2024.200308_bib121","doi-asserted-by":"crossref","first-page":"1578","DOI":"10.1002\/ijc.34153","article-title":"Evaluation of FAM19A4\/miR124-2 methylation performance in the management of CIN3 diagnosed pregnant women","volume":"151","author":"Hampl","year":"2022","journal-title":"Int. J. Cancer"},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib122","doi-asserted-by":"crossref","first-page":"320","DOI":"10.1002\/ijc.33207","article-title":"Estimating the direct effect of human papillomavirus vaccination on the lifetime risk of screen-detected cervical precancer","volume":"148","author":"Inturrisi","year":"2021","journal-title":"Int. J. Cancer"},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib123","doi-asserted-by":"crossref","first-page":"89","DOI":"10.1016\/S1470-2045(11)70286-8","article-title":"Overall efficacy of HPV-16\/18 AS04-adjuvanted vaccine against grade 3 or greater cervical intraepithelial neoplasia: 4-year end-of-study analysis of the randomised, double-blind PATRICIA trial","volume":"13","author":"Lehtinen","year":"2012","journal-title":"Lancet Oncol."},{"issue":"9576","key":"10.1016\/j.tvr.2024.200308_bib124","doi-asserted-by":"crossref","first-page":"1861","DOI":"10.1016\/S0140-6736(07)60852-6","article-title":"Effect of prophylactic human papillomavirus L1 virus-like-particle vaccine on risk of cervical intraepithelial neoplasia grade 2, grade 3, and adenocarcinoma in situ: a combined analysis of four randomised clinical trials","volume":"369","author":"Ault","year":"2007","journal-title":"Lancet (London, England)"},{"issue":"9","key":"10.1016\/j.tvr.2024.200308_bib125","doi-asserted-by":"crossref","first-page":"1549","DOI":"10.1002\/ijc.35044","article-title":"Low methylation marker levels among human papillomavirus-vaccinated women with cervical high-grade squamous intraepithelial lesions","volume":"155","author":"Louvanto","year":"2024","journal-title":"Int. J. Cancer"},{"issue":"3","key":"10.1016\/j.tvr.2024.200308_bib126","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2018-001351","article-title":"Self-sampling for human papillomavirus (HPV) testing: a systematic review and meta-analysis","volume":"4","author":"Yeh","year":"2019","journal-title":"BMJ Glob. Health"},{"issue":"5","key":"10.1016\/j.tvr.2024.200308_bib127","doi-asserted-by":"crossref","DOI":"10.1136\/bmjgh-2020-003743","article-title":"HPV self-sampling for cervical cancer screening: a systematic review of values and preferences","volume":"6","author":"Nishimura","year":"2021","journal-title":"BMJ Glob. Health"},{"key":"10.1016\/j.tvr.2024.200308_bib128","article-title":"Clinical performance of high-risk HPV testing on self-samples versus clinician samples in routine primary HPV screening in The Netherlands: an observational study","volume":"11","author":"Inturrisi","year":"2021","journal-title":"Lancet Reg Health Eur"},{"issue":"5","key":"10.1016\/j.tvr.2024.200308_bib129","doi-asserted-by":"crossref","first-page":"579","DOI":"10.1038\/bjc.2016.200","article-title":"FAM19A4 methylation analysis in self-samples compared with cervical scrapes for detecting cervical (pre)cancer in HPV-positive women","volume":"115","author":"Luttmer","year":"2016","journal-title":"Br. J. Cancer"},{"issue":"2","key":"10.1016\/j.tvr.2024.200308_bib130","doi-asserted-by":"crossref","first-page":"341","DOI":"10.1016\/j.ygyno.2016.02.012","article-title":"Validation of the FAM19A4\/mir124-2 DNA methylation test for both lavage- and brush-based self-samples to detect cervical (pre)cancer in HPV-positive women","volume":"141","author":"De Strooper","year":"2016","journal-title":"Gynecol. Oncol."},{"issue":"6","key":"10.1016\/j.tvr.2024.200308_bib131","doi-asserted-by":"crossref","first-page":"1095","DOI":"10.1038\/bjc.2014.392","article-title":"DNA methylation analysis in self-sampled brush material as a triage test in hrHPV-positive women","volume":"111","author":"Boers","year":"2014","journal-title":"Br. J. Cancer"},{"key":"10.1016\/j.tvr.2024.200308_bib132","doi-asserted-by":"crossref","first-page":"418","DOI":"10.1186\/s12885-015-1411-x","article-title":"Concordance analysis of methylation biomarkers detection in self-collected and physician-collected samples in cervical neoplasm","volume":"15","author":"Chang","year":"2015","journal-title":"BMC Cancer"},{"key":"10.1016\/j.tvr.2024.200308_bib133","doi-asserted-by":"crossref","DOI":"10.1016\/j.modpat.2024.100528","article-title":"Methylation analysis to detect CIN3+ in hrHPV-positive self-samples from the population-based cervical cancer screening program","author":"de Waard","year":"2024","journal-title":"Mod. Pathol. : an official journal of the United States and Canadian Academy of Pathology, Inc."},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib134","doi-asserted-by":"crossref","first-page":"103","DOI":"10.1186\/s13148-023-01517-6","article-title":"Identification of a methylation panel as an alternative triage to detect CIN3+ in hrHPV-positive self-samples from the population-based cervical cancer screening programme","volume":"15","author":"de Waard","year":"2023","journal-title":"Clin. Epigenet."},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib135","doi-asserted-by":"crossref","first-page":"104","DOI":"10.1038\/s41416-023-02277-z","article-title":"Evaluation of DNA methylation biomarkers ASCL1 and LHX8 on HPV-positive self-collected samples from primary HPV-based screening","volume":"129","author":"Verhoef","year":"2023","journal-title":"Br. J. Cancer"},{"issue":"1","key":"10.1016\/j.tvr.2024.200308_bib136","doi-asserted-by":"crossref","first-page":"7862","DOI":"10.1038\/s41598-021-87329-1","article-title":"Triage of human papillomavirus infected women by methylation analysis in first-void urine","volume":"11","author":"Van Keer","year":"2021","journal-title":"Sci. Rep."},{"issue":"10","key":"10.1016\/j.tvr.2024.200308_bib137","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1158\/1078-0432.CCR-21-3710","article-title":"HPV and DNA methylation testing in urine for cervical intraepithelial neoplasia and cervical cancer detection","volume":"28","author":"Van den Helder","year":"2022","journal-title":"Clin. Cancer Res. : An Off. J. American Assoc. Cancer Res."},{"key":"10.1016\/j.tvr.2024.200308_bib138","article-title":"Methylation analysis in urine fractions for optimal CIN3 and cervical cancer detection","volume":"9","author":"Van den Helder","year":"2020","journal-title":"Papillomavirus research (Amsterdam, Netherlands)"},{"issue":"6","key":"10.1016\/j.tvr.2024.200308_bib139","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1002\/ijc.34286","article-title":"Assessing the risk of cervical neoplasia in the post-HPV vaccination era","volume":"152","author":"Lehtinen","year":"2023","journal-title":"Int. J. Cancer"},{"issue":"4","key":"10.1016\/j.tvr.2024.200308_bib140","doi-asserted-by":"crossref","DOI":"10.1002\/jcla.22854","article-title":"Intra- and inter-laboratory agreement of the FAM19A4\/mir124-2 methylation test: results from an international study","volume":"33","author":"Floore","year":"2019","journal-title":"J. Clin. Lab. Anal."}],"container-title":["Tumour Virus Research"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666679024000326?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S2666679024000326?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,6,13]],"date-time":"2025-06-13T03:48:19Z","timestamp":1749786499000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S2666679024000326"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6]]},"references-count":138,"alternative-id":["S2666679024000326"],"URL":"https:\/\/doi.org\/10.1016\/j.tvr.2024.200308","relation":{},"ISSN":["2666-6790"],"issn-type":[{"value":"2666-6790","type":"print"}],"subject":[],"published":{"date-parts":[[2025,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Clinical indications for host-cell DNA methylation markers in cervical screening and management of cervical intraepithelial neoplasia: A review","name":"articletitle","label":"Article Title"},{"value":"Tumour Virus Research","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.tvr.2024.200308","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"200308"}}