{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T10:02:27Z","timestamp":1787911347480,"version":"build-2784847793"},"reference-count":50,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2023,7,1]],"date-time":"2023-07-01T00:00:00Z","timestamp":1688169600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ultrasonics"],"published-print":{"date-parts":[[2023,7]]},"DOI":"10.1016\/j.ultras.2023.106974","type":"journal-article","created":{"date-parts":[[2023,3,9]],"date-time":"2023-03-09T20:49:19Z","timestamp":1678394959000},"page":"106974","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":6,"special_numbering":"C","title":["Treatment of mammary cancer with focused ultrasound: A pilot study in canine and feline patients"],"prefix":"10.1016","volume":"132","author":[{"given":"Anastasia","family":"Antoniou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyriakos","family":"Spanoudes","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christakis","family":"Damianou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ultras.2023.106974_b0005","doi-asserted-by":"crossref","first-page":"976","DOI":"10.1111\/j.1939-1676.2008.0133.x","article-title":"Cancer Incidence in Pet Dogs: Findings of the Animal Tumor Registry of Genoa, Italy","volume":"22","author":"Merlo","year":"2008","journal-title":"J Vet Intern Med"},{"issue":"2","key":"10.1016\/j.ultras.2023.106974_b0010","first-page":"322","article-title":"Epidemiological Studies on Canine Mammary Tumour and its Relevance for Breast Cancer Studies","volume":"2","author":"Gupta","year":"2012","journal-title":"IOSR J. Pharm."},{"issue":"1","key":"10.1016\/j.ultras.2023.106974_b0015","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1177\/0300985814528221","article-title":"Prognostic Evaluation of Feline Mammary Carcinomas: A Review of the Literature","volume":"52","author":"Zappulli","year":"2015","journal-title":"Vet. Pathol."},{"issue":"1","key":"10.1016\/j.ultras.2023.106974_b0020","doi-asserted-by":"crossref","first-page":"140","DOI":"10.1111\/vco.12655","article-title":"One-year conditional survival of dogs and cats with invasive mammary carcinomas: A concept inspired from human breast cancer","volume":"19","author":"Chocteau","year":"2021","journal-title":"Vet. Comp. Oncol."},{"issue":"3","key":"10.1016\/j.ultras.2023.106974_b0025","doi-asserted-by":"crossref","first-page":"111","DOI":"10.3390\/vetsci2030111","article-title":"Cats, cancer and comparative oncology","volume":"2","author":"Cannon","year":"2015","journal-title":"Vet. Sci."},{"issue":"2","key":"10.1016\/j.ultras.2023.106974_b0030","doi-asserted-by":"crossref","first-page":"147","DOI":"10.1038\/nrc2273","article-title":"Translation of new cancer treatments from pet dogs to humans","volume":"8","author":"Paoloni","year":"2008","journal-title":"Nat. Rev. Cancer"},{"key":"10.1016\/j.ultras.2023.106974_b0035","doi-asserted-by":"crossref","first-page":"1263","DOI":"10.1016\/B978-1-4377-0660-4.00043-0","article-title":"The Feline Genome and Clinical Implications","author":"Lyons","year":"2012","journal-title":"Cat"},{"issue":"3","key":"10.1016\/j.ultras.2023.106974_b0040","doi-asserted-by":"crossref","first-page":"907","DOI":"10.1158\/0008-5472.907.65.3","article-title":"Spontaneous feline mammary carcinoma is a model of HER2 overexpressing poor prognosis human breast cancer","volume":"65","author":"De Maria","year":"2005","journal-title":"Cancer Res."},{"key":"10.1016\/j.ultras.2023.106974_b0045","article-title":"Comparative Study of Several Cases of Human Breast Cancer and Mammary Caner in Domestic Dogs and Cats","volume":"23","author":"Todorova","year":"2016","journal-title":"Acta Morphol. Anthropol."},{"issue":"3","key":"10.1016\/j.ultras.2023.106974_b0050","doi-asserted-by":"crossref","first-page":"252","DOI":"10.1111\/vco.12092","article-title":"Surgical treatment of mammary carcinomas in dogs with or without postoperative chemotherapy","volume":"14","author":"Tran","year":"2016","journal-title":"Vet. Comp. Oncol."},{"issue":"2","key":"10.1016\/j.ultras.2023.106974_b0055","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1053\/svms.2003.36625","article-title":"Principles of treatment for mammary gland tumors","volume":"18","author":"Novosad","year":"2003","journal-title":"Clin. Tech. Small Anim. Pract."},{"key":"10.1016\/j.ultras.2023.106974_b0060","series-title":"Small Animal Clinical Oncology","first-page":"455","article-title":"Tumors of mammary gland","author":"Rutterman","year":"2001"},{"issue":"3","key":"10.1016\/j.ultras.2023.106974_b0065","doi-asserted-by":"crossref","first-page":"513","DOI":"10.1016\/S0195-5616(85)50054-6","article-title":"Feline Mammary Tumors","volume":"15","author":"Hayes","year":"1985","journal-title":"Vet. Clin. North Am. Small Anim. Pract."},{"issue":"2","key":"10.1016\/j.ultras.2023.106974_b0070","doi-asserted-by":"crossref","first-page":"201","DOI":"10.2460\/javma.1984.185.02.201","article-title":"Prognostic factors for feline mammary tumors","volume":"185","author":"MacEwen","year":"1984","journal-title":"J Am Vet Med Assoc."},{"issue":"3","key":"10.1016\/j.ultras.2023.106974_b0075","first-page":"375","article-title":"Canine malignant mammary gland neoplasms with advanced clinical staging treated with carboplatin and cyclooxygenase inhibitors","volume":"26","author":"Lavalle","year":"2012","journal-title":"In Vivo"},{"key":"10.1016\/j.ultras.2023.106974_b0080","doi-asserted-by":"crossref","first-page":"123","DOI":"10.1111\/j.1939-1676.2008.0244.x","article-title":"Evaluation of Adjuvant Doxorubicin-Based Chemotherapy for the Treatment of Feline Mammary Carcinoma","volume":"23","author":"McNeill","year":"2009","journal-title":"J Vet Intern Med"},{"issue":"4","key":"10.1016\/j.ultras.2023.106974_b0085","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1134\/1.1591291","article-title":"Physical Mechanisms of the Therapeuctic Effect of Ultrasound","volume":"49","author":"Bailey","year":"2003","journal-title":"Acoust. Phys."},{"issue":"3","key":"10.1016\/j.ultras.2023.106974_b0090","doi-asserted-by":"crossref","first-page":"1641","DOI":"10.1121\/1.408550","article-title":"The effect of various physical parameters on the size and shape of necrosed tissue volumeuring ultrasound surgery","volume":"95","author":"Damianou","year":"1994","journal-title":"J. Acoust. Soc. Am."},{"key":"10.1016\/j.ultras.2023.106974_b0095","doi-asserted-by":"crossref","first-page":"590","DOI":"10.1259\/bjr\/17150274","article-title":"High intensity focused ultrasound: surgery of the future?","volume":"76","author":"Kennedy","year":"2003","journal-title":"Br. J. Radiol."},{"issue":"6","key":"10.1016\/j.ultras.2023.106974_b0100","doi-asserted-by":"crossref","first-page":"349","DOI":"10.1016\/j.diii.2018.03.001","article-title":"High intensity focused ultrasound: The fundamentals, clinical applications and research trends","volume":"99","author":"Elhelf","year":"2018","journal-title":"Diagn. Interv. Imaging"},{"issue":"2","key":"10.1016\/j.ultras.2023.106974_b0105","doi-asserted-by":"crossref","first-page":"376","DOI":"10.1002\/jmri.21265","article-title":"MR Thermometry","volume":"27","author":"Rieke","year":"2008","journal-title":"J Magn Reson Imaging"},{"issue":"1","key":"10.1016\/j.ultras.2023.106974_b0110","doi-asserted-by":"crossref","first-page":"10","DOI":"10.3340\/jkns.2018.0180","article-title":"Magnetic resonance-guided focused ultrasound: Current status and future perspectives in thermal ablation and blood-brain barrier opening","volume":"62","author":"Lee","year":"2019","journal-title":"J. Korean Neurosurg. Soc."},{"issue":"1","key":"10.1016\/j.ultras.2023.106974_b0115","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/rcs.1951","article-title":"MRI-guided frameless biopsy robotic system with the inclusion of unfocused ultrasound transducer for brain cancer ablation","volume":"15","author":"Giannakou","year":"2019","journal-title":"Int. J. Med. Robot. Comput. Assist. Surg."},{"key":"10.1016\/j.ultras.2023.106974_b0120","doi-asserted-by":"crossref","first-page":"46","DOI":"10.1002\/rcs.1653","article-title":"MRI guided focused ultrasound robotic system for the treatment of gynaecological tumors","volume":"12","author":"Epaminonda","year":"2016","journal-title":"Int. J. Med. Robot. Comput. Assist. Surg."},{"key":"10.1016\/j.ultras.2023.106974_b0125","doi-asserted-by":"crossref","first-page":"247","DOI":"10.1002\/rcs.1601","article-title":"Review of MRI positioning devices for guiding focused ultrasound systems","volume":"11","author":"Yiallouras","year":"2015","journal-title":"Int. J. Med. Robot. Comput. Assist. Surg."},{"issue":"4","key":"10.1016\/j.ultras.2023.106974_b0130","doi-asserted-by":"crossref","first-page":"e1804","DOI":"10.1002\/rcs.1804","article-title":"MRI guided focused ultrasound robotic system for animal experiments","volume":"13","author":"Yiannakou","year":"2017","journal-title":"Int. J. Med. Robot. Comput. Assist. Surg."},{"issue":"1","key":"10.1016\/j.ultras.2023.106974_b0135","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/rcs.1753","article-title":"MRI-guided focused ultrasound robotic system for the treatment of bone cancer","volume":"13","author":"Menikou","year":"2017","journal-title":"Int. J. Med. Robot. Comput. Assist. Surg."},{"key":"10.1016\/j.ultras.2023.106974_b0140","unstructured":"Veterinary Medicine: At a Glance, Focused Ultrasound Foundation. [Online]. Available: https:\/\/www.fusfoundation.org\/the-foundation\/initiatives\/focused-ultrasound-for-veterinary-medicine-at-a-glance\/ (Accessed: 29-Nov-2022)."},{"key":"10.1016\/j.ultras.2023.106974_b0145","unstructured":"Focused Ultrasound Foundation Launches Veterinary Program., Focused Ultrasound Foundation, 2017. [Online]. Available: https:\/\/www.fusfoundation.org\/posts\/focused-ultrasound-foundation-launches-veterinary-program\/ (Accessed: 29-Nov-2022)."},{"key":"10.1016\/j.ultras.2023.106974_b0150","doi-asserted-by":"crossref","first-page":"126","DOI":"10.1016\/j.tvjl.2018.02.019","article-title":"Treatment of solid tumors in dogs using veterinary high-intensity focused ultrasound: A retrospective clinical study","volume":"234","author":"Ryu","year":"2018","journal-title":"Vet. J."},{"issue":"1","key":"10.1016\/j.ultras.2023.106974_b0155","doi-asserted-by":"crossref","first-page":"205","DOI":"10.1080\/02656736.2018.1489072","article-title":"Feasibility of targeting canine soft tissue sarcoma with MR-guided high-intensity focused ultrasound","volume":"35","author":"Seward","year":"2018","journal-title":"Int. J. Hyperth."},{"issue":"1","key":"10.1016\/j.ultras.2023.106974_b0160","doi-asserted-by":"crossref","first-page":"552","DOI":"10.1080\/02656736.2021.1903582","article-title":"Focused ultrasound ablation of a large canine oral tumor achieves efficient tumor remission: a case report","volume":"38","author":"Ranjan","year":"2021","journal-title":"Int. J. Hyperthermia"},{"issue":"4","key":"10.1016\/j.ultras.2023.106974_b0165","doi-asserted-by":"crossref","first-page":"895","DOI":"10.1007\/s40477-022-00672-5","article-title":"Treatment of canine and feline sarcoma using MR-guided focused ultrasound system","volume":"25","author":"Antoniou","year":"2022","journal-title":"J. Ultrasound"},{"issue":"6","key":"10.1016\/j.ultras.2023.106974_b0170","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1002\/rcs.2165","article-title":"Focused ultrasound robotic system for very small bore magnetic resonance imaging","volume":"16","author":"Damianou","year":"2020","journal-title":"Int. J. Med. Robot. Comput. Assist. Surg."},{"issue":"7","key":"10.1016\/j.ultras.2023.106974_b0175","doi-asserted-by":"crossref","first-page":"1343","DOI":"10.1002\/jum.15514","article-title":"Magnetic Resonance Imaging-Guided Focused Ultrasound Positioning System for Preclinical Studies in Small Animals","volume":"40","author":"Drakos","year":"2020","journal-title":"J. Ultrasound Med."},{"issue":"1","key":"10.1016\/j.ultras.2023.106974_b0180","article-title":"MRI-Guided Focused Ultrasound Robotic System for Preclinical use, J. Vet. Med","volume":"4","author":"Drakos","year":"2021","journal-title":"Anim. Sci."},{"issue":"5","key":"10.1016\/j.ultras.2023.106974_b0185","doi-asserted-by":"crossref","DOI":"10.1002\/rcs.2299","article-title":"Robotic system for magnetic resonance guided focused ultrasound ablation of abdominal cancer","volume":"17","author":"Antoniou","year":"2021","journal-title":"Int. J. Med. Robot. Comput. Assist. Surg."},{"issue":"2","key":"10.1016\/j.ultras.2023.106974_b0190","doi-asserted-by":"crossref","first-page":"E113","DOI":"10.1016\/j.jstrokecerebrovasdis.2013.09.005","article-title":"MRI-guided Sonothrombolysis of Rabbit Carotid Artery","volume":"23","author":"Damianou","year":"2014","journal-title":"J. Stroke Cerebrovasc. Dis."},{"issue":"11","key":"10.1016\/j.ultras.2023.106974_b0195","doi-asserted-by":"crossref","first-page":"2257","DOI":"10.1002\/jum.14256","article-title":"Amyloid \u03b2 plaque reduction with antibodies crossing the blood-brain barrier, which was opened in 3 sessions of focused ultrasound in a rabbit model","volume":"36","author":"Alecou","year":"2017","journal-title":"J. Ultrasound Med."},{"key":"10.1016\/j.ultras.2023.106974_b0200","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultras.2021.106513","article-title":"Experimental evaluation of the near-field and far-field heating of focused ultrasound using the thermal dose concept","volume":"116","author":"Filippou","year":"2021","journal-title":"Ultrasonics"},{"key":"10.1016\/j.ultras.2023.106974_b0205","doi-asserted-by":"crossref","unstructured":"M. A. Miller, J.F. Zachary, Mechanisms and Morphology of Cellular Injury, Adaptation, and Death. Pathologic Bases of Veterinary Disease, J. F. Zachary, Ed., 2017, pp. 2-43.","DOI":"10.1016\/B978-0-323-35775-3.00001-1"},{"key":"10.1016\/j.ultras.2023.106974_b0210","doi-asserted-by":"crossref","first-page":"559","DOI":"10.1002\/jum.16053","article-title":"Combination of Focused Ultrasound, Immunotherapy, and Chemotherapy: New Perspectives in Breast Cancer Therapy","volume":"42","author":"Dahan","year":"2022","journal-title":"J. Ultrasound Med."},{"key":"10.1016\/j.ultras.2023.106974_b0215","doi-asserted-by":"crossref","first-page":"794","DOI":"10.3332\/ecancer.2018.794","article-title":"High-intensity focused ultrasound in the treatment of breast tumours","volume":"12","author":"Peek","year":"2018","journal-title":"Ecancermedicalscience"},{"issue":"2","key":"10.1016\/j.ultras.2023.106974_b0220","doi-asserted-by":"crossref","first-page":"43","DOI":"10.1007\/s12609-019-0307-1","article-title":"Ablative Treatment of Breast Cancer; Are We There Yet?","volume":"11","author":"Brenin","year":"2019","journal-title":"Curr. Breast Cancer Rep."},{"issue":"25","key":"10.1016\/j.ultras.2023.106974_b0225","doi-asserted-by":"crossref","first-page":"5179","DOI":"10.2174\/0929867327666201111143206","article-title":"High-Intensity Focused Ultrasound in the Treatment of Breast Cancer","volume":"28","author":"Feril","year":"2021","journal-title":"Curr Med Chem"},{"issue":"11","key":"10.1016\/j.ultras.2023.106974_b0230","doi-asserted-by":"crossref","first-page":"4037","DOI":"10.1007\/s00330-016-4222-9","article-title":"First clinical experience with a dedicated MRI-guided high-intensity focused ultrasound system for breast cancer ablation","volume":"26","author":"Merckel","year":"2016","journal-title":"Eur Radiol"},{"issue":"1","key":"10.1016\/j.ultras.2023.106974_b0235","doi-asserted-by":"crossref","first-page":"463","DOI":"10.1080\/02656736.2018.1508757","article-title":"High intensity focused ultrasound (HIFU) for the treatment of symptomatic breast fibroadenoma","volume":"35","author":"Hahn","year":"2018","journal-title":"Int. J. Hyperth."},{"issue":"1","key":"10.1016\/j.ultras.2023.106974_b0240","doi-asserted-by":"crossref","first-page":"50","DOI":"10.1016\/j.ultrasmedbio.2008.08.005","article-title":"Activation of Tumor-Infiltrating Antigen Presenting Cells by High Intensity Focused Ultrasound Ablation of Human Breast Cancer","volume":"35","author":"Xu","year":"2009","journal-title":"Ultrasound Med. Biol."},{"issue":"2","key":"10.1016\/j.ultras.2023.106974_b0245","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1080\/02656736.2021.1900926","article-title":"US-guided high-intensity focused ultrasound (HIFU) of abdominal tumors: outcome, early ablation-related laboratory changes and inflammatory reaction. A single-center experience from Germany","volume":"38","author":"Tonguc","year":"2021","journal-title":"Int. J. Hyperth."},{"issue":"5","key":"10.1016\/j.ultras.2023.106974_b0250","first-page":"494","article-title":"Review of ultrasound mediated drug delivery for cancer treatment: Updates from pre-clinical studies","volume":"3","author":"Couture","year":"2014","journal-title":"Transl. Cancer Res."}],"container-title":["Ultrasonics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041624X23000501?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0041624X23000501?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,22]],"date-time":"2025-09-22T21:57:54Z","timestamp":1758578274000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0041624X23000501"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,7]]},"references-count":50,"alternative-id":["S0041624X23000501"],"URL":"https:\/\/doi.org\/10.1016\/j.ultras.2023.106974","relation":{},"ISSN":["0041-624X"],"issn-type":[{"value":"0041-624X","type":"print"}],"subject":[],"published":{"date-parts":[[2023,7]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Treatment of mammary cancer with focused ultrasound: A pilot study in canine and feline patients","name":"articletitle","label":"Article Title"},{"value":"Ultrasonics","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ultras.2023.106974","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2023 Elsevier B.V. All rights reserved.","name":"copyright","label":"Copyright"}],"article-number":"106974"}}