{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,7]],"date-time":"2026-10-07T05:04:47Z","timestamp":1791349487565,"version":"4.3.1"},"reference-count":29,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2024,12,1]],"date-time":"2024-12-01T00:00:00Z","timestamp":1733011200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2024,10,28]],"date-time":"2024-10-28T00:00:00Z","timestamp":1730073600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ultrasonics Sonochemistry"],"published-print":{"date-parts":[[2024,12]]},"DOI":"10.1016\/j.ultsonch.2024.107137","type":"journal-article","created":{"date-parts":[[2024,10,30]],"date-time":"2024-10-30T20:09:47Z","timestamp":1730318987000},"page":"107137","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":9,"special_numbering":"C","title":["Ultrasonication-mediated synthesis of diblock polymer-based nanoparticles for advanced drug delivery systems: Insights and optimization"],"prefix":"10.1016","volume":"111","author":[{"given":"Nagaraja","family":"Sreeharsha","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Srikruthi","family":"Kunigal Sridhar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Asha","family":"Bhuvanahalli Rangappa","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Prakash","family":"Goudanavar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Purushotham","family":"Karadigere Nagaraju","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nimbagal","family":"Raghavendra Naveen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Predeepkumar","family":"Narayanappa Shiroorkar","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Afzal","family":"Haq Asif","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Girish","family":"Meravanige","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Krishna","family":"Swaroop Duddi Sreehari","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ultsonch.2024.107137_b0005","doi-asserted-by":"crossref","DOI":"10.3390\/pr9081265","article-title":"Influence of process design on the preparation of solid lipid nanoparticles by an ultrasonic-nanoemulsification method","volume":"9","author":"Pucek-Kaczmarek","year":"2021","journal-title":"Processes"},{"key":"10.1016\/j.ultsonch.2024.107137_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/S0378-5173(03)00408-3","article-title":"Ultrasonication of chitosan and chitosan nanoparticles","volume":"265","author":"Tang","year":"2003","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ultsonch.2024.107137_b0015","doi-asserted-by":"crossref","DOI":"10.1021\/la0503808","article-title":"Block copolymers of ethylene oxide and phenyl glycidyl ether: micellization, gelation, and drug solubilization","volume":"21","author":"Taboada","year":"2005","journal-title":"Langmuir"},{"key":"10.1016\/j.ultsonch.2024.107137_b0020","article-title":"Towards the development of polycaprolactone based amphiphilic block copolymers: molecular design, self-assembly and biomedical applications","volume":"45","author":"Li","year":"2015","journal-title":"Mater. Sci. Eng. C"},{"key":"10.1016\/j.ultsonch.2024.107137_b0025","doi-asserted-by":"crossref","DOI":"10.1097\/QAD.0000000000002602","article-title":"The People Living with HIV Stigma Index 2.0: generating critical evidence for change worldwide","volume":"34","author":"Friedland","year":"2020","journal-title":"AIDS"},{"key":"10.1016\/j.ultsonch.2024.107137_b0030","doi-asserted-by":"crossref","DOI":"10.1016\/j.chom.2020.03.014","article-title":"The Biology of the HIV-1 Latent Reservoir and Implications for Cure Strategies","volume":"27","author":"Cohn","year":"2020","journal-title":"Cell Host Microbe"},{"key":"10.1016\/j.ultsonch.2024.107137_b0035","doi-asserted-by":"crossref","DOI":"10.1186\/s12981-021-00415-2","article-title":"HIV\/AIDS late presentation and its associated factors in China from 2010 to 2020: a systematic review and meta-analysis","volume":"18","author":"Sun","year":"2021","journal-title":"AIDS Res. Ther."},{"key":"10.1016\/j.ultsonch.2024.107137_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejmech.2022.114217","article-title":"Natural products and synthetic analogues against HIV: a perspective to develop new potential anti-HIV drugs","volume":"233","author":"Popovi\u0107-Djordjevi\u0107","year":"2022","journal-title":"Eur. J. Med. Chem."},{"key":"10.1016\/j.ultsonch.2024.107137_b0045","doi-asserted-by":"crossref","DOI":"10.1016\/j.compscitech.2004.11.003","article-title":"Nanocomposites in context","volume":"65","author":"Thostenson","year":"2005","journal-title":"Compos. Sci. Technol."},{"key":"10.1016\/j.ultsonch.2024.107137_b0050","article-title":"Solid lipid nanoparticles- a review","volume":"5","author":"Yadav","year":"2013","journal-title":"Int. J. Appl. Pharm."},{"key":"10.1016\/j.ultsonch.2024.107137_b0055","doi-asserted-by":"crossref","DOI":"10.1166\/jbn.2012.1358","article-title":"Biodegradable self-assembled MPEG-PCL micelles for hydrophobic oridonin delivery in vitro","volume":"8","author":"Xue","year":"2012","journal-title":"J. Biomed. Nanotechnol."},{"key":"10.1016\/j.ultsonch.2024.107137_b0060","doi-asserted-by":"crossref","DOI":"10.1007\/s40204-015-0040-4","article-title":"Synthesis and evaluation of MePEG-PCL diblock copolymers: surface properties and controlled release behavior","volume":"4","author":"Mohanty","year":"2015","journal-title":"Prog. Biomater."},{"key":"10.1016\/j.ultsonch.2024.107137_b0065","doi-asserted-by":"crossref","DOI":"10.1038\/aps.2014.113","article-title":"Oral delivery of capsaicin using MPEG-PCL nanoparticles","volume":"36","author":"Peng","year":"2015","journal-title":"Acta Pharmacol. Sin."},{"key":"10.1016\/j.ultsonch.2024.107137_b0070","doi-asserted-by":"crossref","DOI":"10.1007\/s11120-009-9439-x","article-title":"Fourier transform infrared (FTIR) spectroscopy","volume":"101","author":"Berthomieu","year":"2009","journal-title":"Photosynth. Res."},{"key":"10.1016\/j.ultsonch.2024.107137_b0075","series-title":"Understanding NMR Spectroscopy, 2nd Edition | Wiley","author":"Keeler","year":"2010"},{"key":"10.1016\/j.ultsonch.2024.107137_b0080","doi-asserted-by":"crossref","DOI":"10.3390\/pharmaceutics12020126","article-title":"Improving the oral bioavailability of an anti-glioma prodrug cat3 using novel solid lipid nanoparticles containing oleic acid-cat3 conjugates","volume":"12","author":"Wang","year":"2020","journal-title":"Pharmaceutics"},{"key":"10.1016\/j.ultsonch.2024.107137_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2014.12.020","article-title":"Development and evaluation of biodegradable polymeric nanoparticles for the effective delivery of quercetin using a quality by design approach","volume":"61","author":"Dinesh Kumar","year":"2015","journal-title":"LWT"},{"key":"10.1016\/j.ultsonch.2024.107137_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/0378-5173(95)04286-5","article-title":"Crystallization tendency and polymorphic transitions in triglyceride nanoparticles","volume":"129","author":"Bunjes","year":"1996","journal-title":"Int. J. Pharm."},{"key":"10.1016\/j.ultsonch.2024.107137_b0095","doi-asserted-by":"crossref","DOI":"10.1006\/mthe.2001.0431","article-title":"Production and neurotropism of lentivirus vectors pseudotyped with lyssavirus envelope glycoproteins","volume":"4","author":"Desmaris","year":"2001","journal-title":"Mol. Ther."},{"key":"10.1016\/j.ultsonch.2024.107137_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.mam.2005.12.001","article-title":"Detection and monitoring of virus infections by real-time PCR","volume":"27","author":"Watzinger","year":"2006","journal-title":"Mol. Aspects Med."},{"key":"10.1016\/j.ultsonch.2024.107137_b0105","doi-asserted-by":"crossref","DOI":"10.3390\/pr8030316","article-title":"Okra-thioglycolic acid conjugate-synthesis, characterization, and evaluation as a mucoadhesive polymer","volume":"8","author":"Naveen","year":"2020","journal-title":"Processes"},{"key":"10.1016\/j.ultsonch.2024.107137_b0110","article-title":"Preparation and in vitro characterization of 9-nitrocamptothecin-loaded long circulating nanoparticles for delivery in cancer patients","volume":"5","author":"Derakhshandeh","year":"2010","journal-title":"Int. J. Nanomedicine"},{"key":"10.1016\/j.ultsonch.2024.107137_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.colsurfb.2018.05.028","article-title":"Polymeric nanoparticles as a platform for permeability enhancement of class III drug amikacin","volume":"169","author":"Fatima","year":"2018","journal-title":"Colloids Surfaces B Biointerfaces"},{"key":"10.1016\/j.ultsonch.2024.107137_b0120","doi-asserted-by":"crossref","DOI":"10.1002\/jssc.200500328","article-title":"Simple and sensitive high-performance liquid chromatography method for the quantitation of indinavir in rat plasma and central nervous system","volume":"29","author":"Hamidi","year":"2006","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.ultsonch.2024.107137_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.carbpol.2014.02.022","article-title":"Ispaghula mucilage-gellan mucoadhesive beads of metformin HCl: development by response surface methodology","volume":"107","author":"Nayak","year":"2014","journal-title":"Carbohydr. Polym."},{"key":"10.1016\/j.ultsonch.2024.107137_b0130","doi-asserted-by":"crossref","unstructured":"N. Raghavendra Naveen, M. Kurakula, B. Gowthami, Process optimization by response surface methodology for preparation and evaluation of methotrexate loaded chitosan nanoparticles, in: Mater. Today Proc., 2020. https:\/\/doi.org\/10.1016\/j.matpr.2020.01.491.","DOI":"10.1016\/j.matpr.2020.01.491"},{"key":"10.1016\/j.ultsonch.2024.107137_b0135","doi-asserted-by":"crossref","DOI":"10.3390\/gels8020103","article-title":"QbD supported optimization of the alginate-chitosan nanoparticles of simvastatin in enhancing the anti-proliferative activity against tongue carcinoma","volume":"8","author":"Rizg","year":"2022","journal-title":"Gels"},{"key":"10.1016\/j.ultsonch.2024.107137_b0140","doi-asserted-by":"crossref","DOI":"10.3390\/md18040201","article-title":"In situ gel loaded with chitosan-coated simvastatin nanoparticles: promising delivery for effective anti-proliferative activity against tongue carcinoma","volume":"18","author":"Kurakula","year":"2020","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.ultsonch.2024.107137_b0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.eurpolymj.2021.110326","article-title":"Electrospraying, A facile technology unfolding the chitosan based drug delivery and biomedical applications","volume":"147","author":"Kurakula","year":"2021","journal-title":"Eur. Polym. J."}],"container-title":["Ultrasonics Sonochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1350417724003869?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1350417724003869?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,1,19]],"date-time":"2025-01-19T22:06:04Z","timestamp":1737324364000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1350417724003869"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12]]},"references-count":29,"alternative-id":["S1350417724003869"],"URL":"https:\/\/doi.org\/10.1016\/j.ultsonch.2024.107137","relation":{},"ISSN":["1350-4177"],"issn-type":[{"value":"1350-4177","type":"print"}],"subject":[],"published":{"date-parts":[[2024,12]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Ultrasonication-mediated synthesis of diblock polymer-based nanoparticles for advanced drug delivery systems: Insights and optimization","name":"articletitle","label":"Article Title"},{"value":"Ultrasonics Sonochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ultsonch.2024.107137","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2024 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"107137"}}