{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T20:26:18Z","timestamp":1782937578146,"version":"3.54.5"},"reference-count":56,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,1]],"date-time":"2026-02-01T00:00:00Z","timestamp":1769904000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ultrasonics Sonochemistry"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.ultsonch.2026.107760","type":"journal-article","created":{"date-parts":[[2026,2,4]],"date-time":"2026-02-04T00:26:04Z","timestamp":1770164764000},"page":"107760","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Optimization of ultrasound-assisted extraction of Sargassum polycystum for antitumor activity: Multi-objective optimization and mechanistic insights"],"prefix":"10.1016","volume":"127","author":[{"given":"Wanchao","family":"Hou","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Congyao","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingqiu","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5338-3437","authenticated-orcid":false,"given":"Kai","family":"Yu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhua","family":"Lu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Minmin","family":"Qin","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erwei","family":"Hao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiagang","family":"Deng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaotao","family":"Hou","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ultsonch.2026.107760_b0005","article-title":"Sargassum polycystum as natural source of antioxidant and antidiabetic compounds: a solvent-driven metabolomic profiling study","volume":"25","author":"Nurkolis","year":"2026","journal-title":"J. Agr. Food Res."},{"issue":"2025","key":"10.1016\/j.ultsonch.2026.107760_b0010","first-page":"1","article-title":"Dramatic decline of Sargassum in the north Sargasso sea since","volume":"18","author":"Zhang","year":"2015","journal-title":"Nat. Geosci."},{"key":"10.1016\/j.ultsonch.2026.107760_b0015","doi-asserted-by":"crossref","DOI":"10.1016\/j.marenvres.2025.107531","article-title":"The short-term effects of ocean acidification on the epiphytic bacterial community of Sargassum thunbergii via high-throughput sequencing","volume":"212","author":"Ji","year":"2025","journal-title":"Mar. Environ. Res."},{"key":"10.1016\/j.ultsonch.2026.107760_b0020","doi-asserted-by":"crossref","unstructured":"J. Ma, B. Lu, P. Wong, M. Xu, Z. Yang, R. Jiang, Ni. Tao. Sargassum henslowianum polysaccharides induce apoptosis of prostate cancer associated macrophages via the CD206-ERK-ROS pathway. Int. J. Biol. Macromol. 310 (2025) 143482, https:\/\/doi.org\/10.1016\/J.IJBIOMAC.2025.143482.","DOI":"10.1016\/j.ijbiomac.2025.143482"},{"key":"10.1016\/j.ultsonch.2026.107760_b0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2024.115566","article-title":"Gastroprotective effect of fucoidan from Sargassum siliquastrum against ethanol-induced gastric mucosal injury","volume":"201","author":"Sun","year":"2025","journal-title":"Food Res. Int."},{"key":"10.1016\/j.ultsonch.2026.107760_b0030","article-title":"Uncovering the nutraceutical and biorefinery applications of two different marine macroalgae Sargassum polycystum and Rosenvingeaintricata","volume":"60","author":"Vignesh","year":"2024","journal-title":"Biocatal. Agr. Biotech."},{"key":"10.1016\/j.ultsonch.2026.107760_b0035","article-title":"Inductive role of the brown alga Sargassum polycystum on growth and biosynthesis of imperative metabolites and antioxidants of two crop plants","volume":"14","author":"Soha","year":"2023","journal-title":"Front. Plant Sci."},{"key":"10.1016\/j.ultsonch.2026.107760_b0040","doi-asserted-by":"crossref","first-page":"152","DOI":"10.3390\/md23040152","article-title":"Bioactive compounds of marine algae and their potential health and nutraceutical applications: A review","volume":"23","author":"Cadar","year":"2025","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.ultsonch.2026.107760_b0045","doi-asserted-by":"crossref","first-page":"484","DOI":"10.3390\/md19090484","article-title":"Marine algae-derived bioactive compounds: A new wave of nanodrugs?","volume":"19","author":"Farid","year":"2021","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.ultsonch.2026.107760_b0050","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2025.107556","article-title":"Optimization of astaxanthin extraction from red (Gracilaria corticata) and brown (Sargassum polycystum) macroalgae through ultrasonication and microwave processing","volume":"121","author":"Feizi","year":"2025","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.ultsonch.2026.107760_b0055","doi-asserted-by":"crossref","first-page":"968","DOI":"10.1111\/1750-3841.16051","article-title":"Effects of different extraction methods on contents, profiles, and antioxidant abilities of free and bound phenolics of Sargassum polycystum from the South China Sea","volume":"87","author":"Wu","year":"2022","journal-title":"J. Food Sci."},{"key":"10.1016\/j.ultsonch.2026.107760_b0060","article-title":"Extraction and characterization of sodium alginate from native Malaysian brown seaweed Sargassum polycystum","volume":"287","author":"Alallam","year":"2024","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ultsonch.2026.107760_b0065","doi-asserted-by":"crossref","unstructured":"A. Beraich, H. Farissi, Y. Belbachir, F. Cacciola, M. Yahyaoui, A. Choukoud, A. Talhaoui..Traditional and modern extraction methods for Pistacia lentiscus essential oil. Sustain. Chem. Pharm. 40 (2024) 101638-, https:\/\/doi.org\/10.1016\/J.SCP.2024. 101638.","DOI":"10.1016\/j.scp.2024.101638"},{"key":"10.1016\/j.ultsonch.2026.107760_b0070","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2022.106005","article-title":"Ultrasonic-assisted extraction of polyphenolic compounds from Paederia scandens (Lour.) Merr. Using deep eutectic solvent: optimization, identification, and comparison with traditional methods","volume":"86","author":"Liu","year":"2022","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.ultsonch.2026.107760_b0075","article-title":"An insight into Cochlospermum planchonii extracts obtained by traditional and green extraction methods: Relation between chemical compositions and biological properties by multivariate analysis","volume":"147","author":"Acqua","year":"2020","journal-title":"Ind. Crop Prod."},{"key":"10.1016\/j.ultsonch.2026.107760_b0080","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2025.107271","article-title":"Ultrasonic-assisted extraction (UAE) of Javanese turmeric rhizomes using natural deep eutectic solvents (NADES): Screening, optimization, and in vitro cytotoxicity evaluation","volume":"114","author":"Ariestanti","year":"2025","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.ultsonch.2026.107760_b0085","first-page":"1","article-title":"Exploring bioactive compounds in lyophilized grape pomace extracts: comparative analysis of traditional and innovative extraction methods","volume":"19","author":"Ahad","year":"2024","journal-title":"J. Food Meas. Charact."},{"key":"10.1016\/j.ultsonch.2026.107760_b0090","doi-asserted-by":"crossref","unstructured":"W. Peng, X. Wang, W. Wang, Y. Wang, J. Huang, R. Zhou, J. Li. Comparison, optimization and antioxidant activity of ultrasound-assisted natural deep eutectic solvents extraction and traditional method: A greener route for extraction of flavonoid from Moringa oleifera Lam. leaves. Ultrason. Sonochem. 109 (2024) 107003, https:\/\/doi.org\/10.1016\/J.ULTSONCH.2024.107003.","DOI":"10.1016\/j.ultsonch.2024.107003"},{"key":"10.1016\/j.ultsonch.2026.107760_b0095","doi-asserted-by":"crossref","unstructured":"R. Zhao, X. Li, X. Wu, Y. Wu, N. Tang, C. Xu, A. Ben. Optimization, comparison and mechanism of ultrasound-assisted cellulase hydrolysis and ethanol extraction of quercetin, luteolin and apigenin from male inflorescences of Populus alba \u00d7 berolinensis. Ultrason. Sonochem. 123 (2025) 107645, https:\/\/doi.org\/10. 1016\/J.ULTSONCH.2025.107645.","DOI":"10.1016\/j.ultsonch.2025.107645"},{"key":"10.1016\/j.ultsonch.2026.107760_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2025.107678","article-title":"Ultrasonic-Assisted extraction of luteolin from peanut shells using supramolecular solvents and its molecular mechanism","volume":"123","author":"Fang","year":"2025","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.ultsonch.2026.107760_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2025.107665","article-title":"Ultrasound-assisted enzymatic hydrolysis of loach (Misgurnus anguillicaudatus) protein for antioxidant peptides: process optimization, structural characterization, and Keap1\/Nrf2-mediated antioxidant mechanism","volume":"123","author":"Chu","year":"2025","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.ultsonch.2026.107760_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2025.466331","article-title":"Ultrasound-assisted enzymatic extraction optimization of Cistanche deserticola polysaccharides, and combined analysis of the relationship between polysaccharide structure and activity by liquid chromatography and GC-MS","volume":"1761","author":"Yang","year":"2025","journal-title":"J. Chromatogra. A"},{"key":"10.1016\/j.ultsonch.2026.107760_b0115","article-title":"Structural and functional enhancement of okara (soybean residue) proteins using microwave- and ultrasound-assisted enzymatic hydrolysis","volume":"71","author":"He","year":"2025","journal-title":"Food Biosci."},{"key":"10.1016\/j.ultsonch.2026.107760_b0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.seppur.2024.127967","article-title":"Ultrasound assisted intensified enzymatic extraction of total phenolic compounds from pomegranate peels","volume":"350","author":"Patil","year":"2024","journal-title":"Sep. Purif. Technol."},{"key":"10.1016\/j.ultsonch.2026.107760_b0125","doi-asserted-by":"crossref","first-page":"1228","DOI":"10.1007\/s11694-022-01699-2","article-title":"Efficient combination of ionic-liquid-based ultrasound-assisted extraction, complex chromatography, and molecular docking for screening of acetylcholinesterase inhibitors from Ganoderma atru","volume":"17","author":"Hou","year":"2022","journal-title":"J. Food Meas. Charact."},{"key":"10.1016\/j.ultsonch.2026.107760_b0130","first-page":"1","article-title":"Ultrasound-assisted enzymatic extraction of anthocyanins from raspberry wine residues: process optimization, isolation, purification, and bioactivity determination","volume":"1","author":"Xue","year":"2021","journal-title":"Food Anal. Method."},{"key":"10.1016\/j.ultsonch.2026.107760_b0135","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2025.107606","article-title":"Optimization of flavonoids from Astragalus membranaceus stem and leaf waste using nonionic surfactant-integrated ultrasound-assisted extraction","volume":"122","author":"Yang","year":"2025","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.ultsonch.2026.107760_b0140","article-title":"Optimising ultrasound-assisted extraction conditions for maximising phenolic, flavonoid content and antioxidant activity in hog plum peel and seed: A response surface methodology approach","volume":"18","author":"Sayem","year":"2024","journal-title":"J. Agr. Food Res."},{"key":"10.1016\/j.ultsonch.2026.107760_b0145","doi-asserted-by":"crossref","unstructured":"L. Wang, Z. Sun, L. Wang, S. Tian. Optimization of ultrasonic-assisted extraction of polyphenols from Salvia deserta Schang flowers based on response surface methodology and deep neural network and analysis of its in vitro antioxidant activities. Ind. Crop. Prod. 213 (2024) 118389-, https:\/\/doi.org\/10.1016\/J.INDCROP. 2024.118389.","DOI":"10.1016\/j.indcrop.2024.118389"},{"key":"10.1016\/j.ultsonch.2026.107760_b0150","doi-asserted-by":"crossref","DOI":"10.1002\/adem.202500038","article-title":"Multi-objective optimization for strength, porosity, and surface roughness of extrusion-based 3D-printed ZrO2 ceramics using response surface methodology and nondominated sorting genetic algorithm-II","volume":"27","author":"Zhang","year":"2025","journal-title":"Adv. Eng. Mater."},{"key":"10.1016\/j.ultsonch.2026.107760_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.seppur.2024.130363","article-title":"Multi-objective optimization of supersonic separator for gas removal and carbon capture using three-field two-phase flow model and non-dominated sorting Genetic Algorithm-II (NSGA-II)","volume":"358","author":"Ding","year":"2025","journal-title":"Sep. Purif. Technol."},{"key":"10.1016\/j.ultsonch.2026.107760_b0160","doi-asserted-by":"crossref","first-page":"1690","DOI":"10.3390\/pr13061690","article-title":"Multi-objective optimization of the dip-coating parameters for polylactic acid plus bone screws using taguchi method, response surface methodology, and non-dominated sorting genetic algorithm II","volume":"13","author":"Luthfianto","year":"2025","journal-title":"Processes"},{"key":"10.1016\/j.ultsonch.2026.107760_b0165","doi-asserted-by":"crossref","DOI":"10.1016\/j.lungcan.2025.108856","article-title":"Real-world use of and clinical outcomes with dacomitinib as first-line therapy in Asian patients with EGFR mutation\u2013positive locally advanced or metastatic non-small cell lung cancer: Final analysis of the ARIA study","volume":"211","author":"Wu","year":"2026","journal-title":"Lung Cancer"},{"key":"10.1016\/j.ultsonch.2026.107760_b0170","doi-asserted-by":"crossref","first-page":"10983","DOI":"10.1038\/s41467-025-66800-x","article-title":"ERBB2 signaling drives immune cell evasion and resistance against immunotherapy in small cell lung cancer","volume":"16","author":"Meder","year":"2025","journal-title":"Nat. Commun."},{"key":"10.1016\/j.ultsonch.2026.107760_b0175","doi-asserted-by":"crossref","first-page":"7032","DOI":"10.1126\/sciadv.ady7032","article-title":"Steric disruption of EGFR oligomerization overcomes therapy resistance in non-small cell lung cancer","volume":"11","author":"Song","year":"2025","journal-title":"Sci. Adv."},{"key":"10.1016\/j.ultsonch.2026.107760_b0180","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2025.157445","article-title":"Betulin, an active component from Chinese herb birch bark, suppresses tumor angiogenesis and tumor growth by inhibiting the PAX2\/VEGF-A\/VEGR2 signaling pathway in non-small cell lung cancer","volume":"148","author":"Li","year":"2025","journal-title":"Phytomed"},{"key":"10.1016\/j.ultsonch.2026.107760_b0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.jep.2025.120120","article-title":"Exploring the Mechanism of Feiyanning formula and its extract Apigenin Against EGFR-TKIs resistance in non-small cell lung cancer based on UPLC-HRMS and experimental validation","volume":"351","author":"Han","year":"2025","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.ultsonch.2026.107760_b0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.ejphar.2024.176608","article-title":"Cycloheptylprodigiosin from marine bacterium Spartinivicinus ruber MCCC 1K03745T induces a novel form of cell death characterized by Golgi disruption and enhanced secretion of cathepsin D in Non-small cell lung cancer cell lines","volume":"974","author":"Lin","year":"2024","journal-title":"Eur. J. Pharmacol."},{"key":"10.1016\/j.ultsonch.2026.107760_b0195","article-title":"Modeling cellular responses in non-small cell lung cancer using marine derived natural products","volume":"81","author":"Nw","year":"2015","journal-title":"Planta Med."},{"key":"10.1016\/j.ultsonch.2026.107760_b0200","doi-asserted-by":"crossref","first-page":"68","DOI":"10.3390\/md23020068","article-title":"Comparative evaluation of the antibacterial and antitumor activities of marine alkaloid 3,10-dibromofascaplysin","volume":"23","author":"Zhidkov","year":"2025","journal-title":"Mar. Drugs"},{"key":"10.1016\/j.ultsonch.2026.107760_b0205","article-title":"Danthron, an anthraquinone isolated from a marine fungus, is a new inhibitor of angiogenesis exhibiting interesting antitumor and antioxidant properties","volume":"12","author":"Isabel","year":"2023","journal-title":"Antioxidants"},{"key":"10.1016\/j.ultsonch.2026.107760_b0210","doi-asserted-by":"crossref","unstructured":"C. Yu, Y. Liu, Y. Na, X. Wu. Chemical and flavour dynamics in Cyperus esculentus L. pomace-raspberry composite fruit wine fermentation: A combined UHPLC-OE-MS and HS-SPME-GC\u2013MS approach. Food Chem. X, 32 (2025) 103234-103234, https:\/\/doi.org\/10.1016\/J.FOCHX.2025.103234.","DOI":"10.1016\/j.fochx.2025.103234"},{"key":"10.1016\/j.ultsonch.2026.107760_b0215","doi-asserted-by":"crossref","first-page":"597","DOI":"10.3390\/antiox8120597","article-title":"Impact of extraction conditions on the phenolic composition and antioxidant capacity of grape stem extracts","volume":"8","author":"Moreno","year":"2019","journal-title":"Antioxidants"},{"key":"10.1016\/j.ultsonch.2026.107760_b0220","doi-asserted-by":"crossref","unstructured":"Wo\u017aniak, Marsza\u0142ek, Sk\u0105pska. Extraction of phenolic compounds from sour cherry pomace with supercritical carbon dioxide: Impact of process parameters on the composition and antioxidant properties of extracts. Sep. Sci. Technol. 51 (2016) 1472-1479, https:\/\/doi.org\/10.1080\/01496395.2016.1165705.","DOI":"10.1080\/01496395.2016.1165705"},{"key":"10.1016\/j.ultsonch.2026.107760_b0225","article-title":"Optimization of ethanolic extraction of phenolic antioxidants from lychee and longan seeds using response surface methodology","volume":"12","author":"Samart","year":"2023","journal-title":"Foods"},{"key":"10.1016\/j.ultsonch.2026.107760_b0230","doi-asserted-by":"crossref","DOI":"10.1055\/s-0028-1084620","article-title":"Effects of pH and temperature on the stability of sesquiterpene lactones","volume":"74","author":"Saroglou","year":"2008","journal-title":"Planta Med."},{"key":"10.1016\/j.ultsonch.2026.107760_b0235","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2025.117291","article-title":"Thermally-driven phenolic remodeling in probiotic-fermented red-fleshed pitaya: A dual-strain comparative study via untargeted UPLC-ESI-QTOF-MS\/MS profiling","volume":"221","author":"Chen","year":"2025","journal-title":"Food Res. Int."},{"key":"10.1016\/j.ultsonch.2026.107760_b0240","doi-asserted-by":"crossref","DOI":"10.1002\/rcm.10174","article-title":"A comprehensive strategy to annotate and evaluate galloylated polyphenols of rhodiola crenulata based on improved precursor ion list-data dependent acquisition\/mass spectrometry combined with the biogenetic building block analytics","volume":"40","author":"Jing","year":"2026","journal-title":"Rapid Commun. Mass Sp."},{"key":"10.1016\/j.ultsonch.2026.107760_b0245","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s12161-025-02863-2","article-title":"Salvia lanigera poiret extracts: Study of the phytochemical profiling via GC-MS and HPLC-DAD and bioactivity with ADME analysis","volume":"18","author":"Chahna","year":"2025","journal-title":"Food Anal. Method."},{"key":"10.1016\/j.ultsonch.2026.107760_b0250","doi-asserted-by":"crossref","first-page":"439","DOI":"10.2174\/1573411011309030013","article-title":"Matrix effect in the quantitative determination of mandelic and phenylglyoxylic acid in urine samples by HPLC-MS\/MS with isotopic dilution","volume":"9","author":"Paci","year":"2013","journal-title":"Curr. Anal. Chem."},{"key":"10.1016\/j.ultsonch.2026.107760_b0255","doi-asserted-by":"crossref","first-page":"2306","DOI":"10.1016\/j.fshw.2023.03.034","article-title":"Fabrication of taxifolin loaded zein-caseinate nanoparticles and its bioavailability in rat","volume":"12","author":"Ying","year":"2023","journal-title":"Food Sci. Hum. Well."},{"key":"10.1016\/j.ultsonch.2026.107760_b0260","doi-asserted-by":"crossref","first-page":"182","DOI":"10.1016\/j.fitote.2011.10.012","article-title":"Pharmacokinetic properties of isorhamnetin, kaempferol and quercetin after oral gavage of total flavones of Hippophae rhamnoides L. in rats using a UPLC-MS method","volume":"83","author":"Li","year":"2011","journal-title":"Fitoterapia"},{"key":"10.1016\/j.ultsonch.2026.107760_b0265","doi-asserted-by":"crossref","first-page":"243","DOI":"10.1002\/fft2.19","article-title":"Investigation of new products and reaction kinetics for myricetin in DMEM via an in situ UPLC-MS-MS analysis","volume":"1","author":"Cao","year":"2020","journal-title":"Food Front."},{"key":"10.1016\/j.ultsonch.2026.107760_b0270","doi-asserted-by":"crossref","unstructured":"R. Cai, H. Liang, X. Li, H. Chai, Yo. Liang, Y. Huang, G. Jiang. Multiple ionization patterns enable UHPLC-Q-Orbitrap MS\/MS to quantify 80 compounds in Tongmai Granule and recommend new anti-counterfeiting Q-markers for Pharmacopoeia. J. Saudi Chem. Soc. 29 (2025) 9-9, https:\/\/doi.org\/10.1007\/S44442- 025-00013-1.","DOI":"10.1007\/s44442-025-00013-1"},{"key":"10.1016\/j.ultsonch.2026.107760_b0275","article-title":"Machine learning based on metabolomics to discriminate Wuyi rock tea production areas and \u201crock flavor\u201d substances","volume":"31","author":"Peng","year":"2025","journal-title":"Food Chem.: X"},{"key":"10.1016\/j.ultsonch.2026.107760_b0280","doi-asserted-by":"crossref","unstructured":"C. Ang, Z. jing, T. wen, L. yao, W. Xin. Evaluation of the inhibition potential of plumbagin against cytochrome P450 using LC-MS\/MS and cocktail approach. Sci. Rep. 6 (2016) 28482, https:\/\/doi.org\/10.1038\/srep28482.","DOI":"10.1038\/srep28482"}],"container-title":["Ultrasonics Sonochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1350417726000258?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1350417726000258?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,3,7]],"date-time":"2026-03-07T02:27:53Z","timestamp":1772850473000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1350417726000258"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":56,"alternative-id":["S1350417726000258"],"URL":"https:\/\/doi.org\/10.1016\/j.ultsonch.2026.107760","relation":{},"ISSN":["1350-4177"],"issn-type":[{"value":"1350-4177","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Optimization of ultrasound-assisted extraction of Sargassum polycystum for antitumor activity: Multi-objective optimization and mechanistic insights","name":"articletitle","label":"Article Title"},{"value":"Ultrasonics Sonochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ultsonch.2026.107760","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"107760"}}