{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,18]],"date-time":"2026-10-18T14:13:27Z","timestamp":1792332807610,"version":"4.4.0"},"reference-count":44,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T00:00:00Z","timestamp":1775001600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,2,24]],"date-time":"2026-02-24T00:00:00Z","timestamp":1771891200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32473096"],"award-info":[{"award-number":["32473096"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ultrasonics Sonochemistry"],"published-print":{"date-parts":[[2026,4]]},"DOI":"10.1016\/j.ultsonch.2026.107795","type":"journal-article","created":{"date-parts":[[2026,2,25]],"date-time":"2026-02-25T00:22:34Z","timestamp":1771978954000},"page":"107795","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":7,"special_numbering":"C","title":["COSMO-RS guided screening of deep eutectic solvents and ultrasound-assisted extraction for resveratrol from Polygonum cuspidatum"],"prefix":"10.1016","volume":"127","author":[{"given":"Yitong","family":"Lu","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zimeng","family":"Song","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengjun","family":"Chen","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3059-022X","authenticated-orcid":false,"given":"Zunlai","family":"Sheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiyong","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ultsonch.2026.107795_b0005","article-title":"Resveratrol: a comprehensive review of its multifaceted health benefits, mechanisms of action, and potential therapeutic applications in chronic disease","volume":"3","author":"Vikal","year":"2024","journal-title":"Pharmacol. Res. Nat. Prod."},{"key":"10.1016\/j.ultsonch.2026.107795_b0010","doi-asserted-by":"crossref","first-page":"1216","DOI":"10.3390\/pr12061216","article-title":"Retaining resveratrol content in berries and berry products with agricultural and processing techniques: review","volume":"12","author":"Ispiryan","year":"2024","journal-title":"Processes"},{"key":"10.1016\/j.ultsonch.2026.107795_b0015","doi-asserted-by":"crossref","first-page":"5757","DOI":"10.1007\/s10787-025-01947-z","article-title":"Resveratrol: potential therapeutic effects on ocular health","volume":"33","author":"Biju","year":"2025","journal-title":"Inflammopharmacology"},{"key":"10.1016\/j.ultsonch.2026.107795_b0020","doi-asserted-by":"crossref","DOI":"10.1002\/ardp.70109","article-title":"The potential of resveratrol as an anticancer agent: updated overview of mechanisms, applications, and perspectives","volume":"358","author":"Islam","year":"2025","journal-title":"Arch. Pharm."},{"key":"10.1016\/j.ultsonch.2026.107795_b0025","doi-asserted-by":"crossref","DOI":"10.1016\/j.jnutbio.2025.110095","article-title":"Comparative study of lipophilicity, cell membrane permeability, and intracellular antioxidant capacity of resveratrol and pterostilbene","volume":"147","author":"Huang","year":"2026","journal-title":"J. Nutr. Biochem."},{"key":"10.1016\/j.ultsonch.2026.107795_b0030","doi-asserted-by":"crossref","first-page":"26524","DOI":"10.1021\/acs.jafc.4c09118","article-title":"Control of Starch molecular weight by enzyme treatment facilitates the formation of V-Type starch\u2013resveratrol complexes in a high-pressure homogenization environment and their modulation effects on the gut microbiota","volume":"72","author":"Zheng","year":"2024","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.ultsonch.2026.107795_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.biortech.2025.133106","article-title":"Metabolic engineering of Escherichia coli for enhanced biosynthesis of polydatin","volume":"437","author":"Sheng","year":"2025","journal-title":"Bioresour. Technol."},{"key":"10.1016\/j.ultsonch.2026.107795_b0040","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2024.118386","article-title":"Resveratrol production from Polygonum cuspidatum by one-pot green extraction and bioprocessing of polydatin","volume":"212","author":"Li","year":"2024","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.ultsonch.2026.107795_b0045","doi-asserted-by":"crossref","first-page":"567","DOI":"10.3390\/plants14233572","article-title":"Industrial applications of different parts of flatland polygonum cuspidatum by combining microwave-assisted extraction and fermentation process","volume":"14","author":"Chen","year":"2025","journal-title":"Plants"},{"key":"10.1016\/j.ultsonch.2026.107795_b0050","doi-asserted-by":"crossref","first-page":"692","DOI":"10.3390\/cimb47090692","article-title":"New perspectives on the use of resveratrol in the treatment of metabolic and estrogen-dependent conditions through hormonal modulation and anti-inflammatory effects","volume":"47","author":"Renke","year":"2025","journal-title":"Curr. Issues Mol. Biol."},{"key":"10.1016\/j.ultsonch.2026.107795_b0055","article-title":"Polydatin, a glycoside of resveratrol, is better than resveratrol in alleviating non-alcoholic fatty liver disease in mice fed a high-fructose diet","volume":"9","author":"Zhao","year":"2022","journal-title":"Front. Nutr."},{"key":"10.1016\/j.ultsonch.2026.107795_b0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2023.117964","article-title":"Semi-solid-state fermentation of Polygonum cuspidatum roots by a novel endophytic fungus Penicillium rubens with capabilities of cell wall hydrolysis and polydatin deglycosylation to improve the yield of high-value resveratrol","volume":"209","author":"He","year":"2024","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.ultsonch.2026.107795_b0065","doi-asserted-by":"crossref","first-page":"654","DOI":"10.3390\/antiox14060654","article-title":"Emerging trends in green extraction techniques, chemical modifications, and drug delivery systems for resveratrol","volume":"14","author":"Trombino","year":"2025","journal-title":"Antioxidants"},{"key":"10.1016\/j.ultsonch.2026.107795_b0070","doi-asserted-by":"crossref","unstructured":"H. Zhao, J. Wang, Y. Han, X. Wang, Z. Sheng, 2024. Optimization of process conditions for ionic liquid-based ultrasound-enzyme-assisted extraction of resveratrol from Polygonum Cuspidatum. Ultrason. Sonochem. 108, 106973. doi:10.1016\/j.ultsonch.2024.106973.","DOI":"10.1016\/j.ultsonch.2024.106973"},{"key":"10.1016\/j.ultsonch.2026.107795_b0075","doi-asserted-by":"crossref","first-page":"2295","DOI":"10.3390\/pr12102295","article-title":"Ultrasonic-assisted extraction and antioxidant evaluation of resveratrol from peanut sprouts","volume":"12","author":"Xu","year":"2024","journal-title":"Processes"},{"key":"10.1016\/j.ultsonch.2026.107795_b0080","article-title":"Applications for natural deep eutectic solvents in chinese herbal medicines","volume":"13","author":"Li","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ultsonch.2026.107795_b0085","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2022.132633","article-title":"Microwave-assisted extraction of antioxidant compounds from by-products of Turkish hazelnut (Corylus avellana L.) using natural deep eutectic solvents: modeling, optimization and phenolic characterization","volume":"385","author":"Bener","year":"2022","journal-title":"Food Chem."},{"key":"10.1016\/j.ultsonch.2026.107795_b0090","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2021.114140","article-title":"Simultaneous transformation and extraction of resveratrol from Polygonum cuspidatum using acidic natural deep eutectic solvent","volume":"173","author":"Wang","year":"2021","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.ultsonch.2026.107795_b0095","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.141279","article-title":"Electron beam irradiation coupled ultrasound-assisted natural deep eutectic solvents extraction: a green and efficient extraction strategy for proanthocyanidin from walnut green husk","volume":"463","author":"Qi","year":"2025","journal-title":"Food Chem."},{"key":"10.1016\/j.ultsonch.2026.107795_b0100","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2024.140046","article-title":"A high-permeability method for extracting purple yam saponins based on ultrasonic-assisted natural deep eutectic solvent","volume":"457","author":"Hou","year":"2024","journal-title":"Food Chem."},{"key":"10.1016\/j.ultsonch.2026.107795_b0105","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2020.128498","article-title":"One-pot method based on deep eutectic solvent for extraction and conversion of polydatin to resveratrol from Polygonum cuspidatum","volume":"343","author":"Sun","year":"2021","journal-title":"Food Chem."},{"key":"10.1016\/j.ultsonch.2026.107795_b0110","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2024.112425","article-title":"The Design of natural deep eutectic solvent for the extraction of Acetyl-11-Keto-\u03b2-Boswellic acid using COSMO-RS","volume":"208","author":"Norhidzam","year":"2025","journal-title":"Microchem. J."},{"key":"10.1016\/j.ultsonch.2026.107795_b0115","doi-asserted-by":"crossref","DOI":"10.1016\/j.microc.2025.115042","article-title":"Natural deep eutectic solvents combined with COSMO-RS model for efficient extraction of essential oil from Fructus Aurantii: theoretical screening, process optimization, biological activity and mechanism","volume":"217","author":"Du","year":"2025","journal-title":"Microchem. J."},{"key":"10.1016\/j.ultsonch.2026.107795_b0120","doi-asserted-by":"crossref","DOI":"10.1016\/j.indcrop.2025.120578","article-title":"Microwave-assisted extraction of luteolin from peanut shells using natural deep eutectic solvents and its molecular mechanism","volume":"225","author":"Zhang","year":"2025","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.ultsonch.2026.107795_b0125","doi-asserted-by":"crossref","DOI":"10.1016\/j.ces.2025.122709","article-title":"Enhanced solubility of carbamazepine using cholinium-based ionic liquid: from COSMO-RS screening to molecular dynamics simulation","volume":"320","author":"Zhuang","year":"2026","journal-title":"Chem. Eng. Sci."},{"key":"10.1016\/j.ultsonch.2026.107795_b0130","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodchem.2025.145440","article-title":"Integration of COSMO-RS and ANN-GA for extraction of echinacoside and acteoside from Cistanche deserticola using natural deep eutectic solvents","volume":"492","author":"Zeng","year":"2025","journal-title":"Food Chem."},{"key":"10.1016\/j.ultsonch.2026.107795_b0135","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1016\/j.seppur.2011.06.042","article-title":"Extraction of trans-resveratrol from red wine and optimization by response surface methodology","volume":"81","author":"Rabesiaka","year":"2011","journal-title":"Sep. Purif. Technol."},{"key":"10.1016\/j.ultsonch.2026.107795_b0140","doi-asserted-by":"crossref","DOI":"10.1016\/j.foodres.2025.116859","article-title":"Eco-friendly extraction of polysaccharides from Moringa oleifera Lam. leaves using COSMO-RS screened natural deep eutectic solvents","volume":"217","author":"Peng","year":"2025","journal-title":"Food Res. Int."},{"key":"10.1016\/j.ultsonch.2026.107795_b0145","doi-asserted-by":"crossref","DOI":"10.1016\/j.lwt.2025.117687","article-title":"Efficient polyphenol extraction from Moringa oleifera Lam. leaves using natural deep eutectic solvents: COSMO-RS screening, ANN-GA optimization and antioxidant activity evaluation","volume":"223","author":"Peng","year":"2025","journal-title":"LWT"},{"key":"10.1016\/j.ultsonch.2026.107795_b0150","doi-asserted-by":"crossref","DOI":"10.1016\/j.molliq.2025.126949","article-title":"Solubility Enhancement of valine using deep eutectic Solvents: COSMO-RS and experimental validation","volume":"423","author":"Aman","year":"2025","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.ultsonch.2026.107795_b0155","doi-asserted-by":"crossref","DOI":"10.1016\/j.ces.2025.121425","article-title":"A comprehensive approach to incorporating intermolecular dispersion into the openCOSMO-RS model. Part 1. Halocarbons","volume":"309","author":"Grigorash","year":"2025","journal-title":"Chem. Eng. Sci."},{"key":"10.1016\/j.ultsonch.2026.107795_b0160","doi-asserted-by":"crossref","unstructured":"M.A. Escobedo-Monge, S. de-la-Huerta-Sainz, P.A. Marcos, J.A. Esteban-Ollo, L. Montejo-Gil, M. Conde-Rioll, M. Atilhan, A. Bol, S. Aparicio, 2025. Rational Design of Eco-Friendly Deep Eutectic Solvent Systems for the Recovery of High-Value Phytosterol Compounds. Food Bioprocess Technol. 18, 7646 \u2013 7660. doi:10.1007\/s11947-025-03896-5.","DOI":"10.1007\/s11947-025-03896-5"},{"key":"10.1016\/j.ultsonch.2026.107795_b0165","doi-asserted-by":"crossref","first-page":"e1338","DOI":"10.1002\/wcms.1338","article-title":"The COSMO and COSMO-RS solvation models","volume":"8","author":"Klamt","year":"2018","journal-title":"WIREs Comput. Mol. Sci."},{"key":"10.1016\/j.ultsonch.2026.107795_b0170","doi-asserted-by":"crossref","first-page":"101","DOI":"10.1146\/annurev-chembioeng-073009-100903","article-title":"COSMO-RS: an alternative to simulation for calculating thermodynamic properties of liquid mixtures","volume":"1","author":"Andreas","year":"2010","journal-title":"Annu. Rev. Chem. Biomol. Eng."},{"key":"10.1016\/j.ultsonch.2026.107795_b0175","doi-asserted-by":"crossref","first-page":"3766","DOI":"10.1021\/acssuschemeng.3c07894","article-title":"Extraction of 5-hydroxymethylfurfural and furfural in aqueous biphasic systems: a COSMO-RS guided approach to greener solvent selection","volume":"12","author":"Soukup-Carne","year":"2024","journal-title":"ACS Sustainable Chem. Eng."},{"key":"10.1016\/j.ultsonch.2026.107795_b0180","doi-asserted-by":"crossref","first-page":"11110","DOI":"10.1021\/acs.iecr.4c00796","article-title":"Assessment of COSMO-RS for predicting liquid\u2013liquid equilibrium in systems containing deep eutectic solvents","volume":"63","author":"Wang","year":"2024","journal-title":"Ind. Eng. Chem. Res."},{"key":"10.1016\/j.ultsonch.2026.107795_b0185","doi-asserted-by":"crossref","DOI":"10.1016\/j.molliq.2024.126333","article-title":"Solubility and extractability enhancement of the main food flavonoids by using choline chloride-based natural deep eutectic solvents","volume":"415","author":"Popovi\u0107","year":"2024","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.ultsonch.2026.107795_b0190","doi-asserted-by":"crossref","DOI":"10.1016\/j.molliq.2023.123520","article-title":"Screening deep eutectic solvents as green extractants for oil from plant seeds based on COSMO-RS model","volume":"393","author":"Al-Maari","year":"2024","journal-title":"J. Mol. Liq."},{"key":"10.1016\/j.ultsonch.2026.107795_b0195","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2023.106646","article-title":"A comprehensive review of ultrasonic assisted extraction (UAE) for bioactive components: principles, advantages, equipment, and combined technologies","volume":"101","author":"Shen","year":"2023","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.ultsonch.2026.107795_b0200","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s44447-025-00014-x","article-title":"Effects of ultrasound-assisted bath, probe, and extraction time on bioactive compounds and antioxidant activity in white tea (Camellia sinensis) extracts from purple- and green-leaf cultivars","volume":"24","author":"Prawira-Atmaja","year":"2025","journal-title":"J. Saudi Soc. Agric. Sci."},{"key":"10.1016\/j.ultsonch.2026.107795_b0205","doi-asserted-by":"crossref","first-page":"789","DOI":"10.3390\/foods14193325","article-title":"Ultrasound-assisted green natural deep eutectic solvent extraction of flavonoids from wild blueberry: process optimization, composition identification, and antioxidant activity","volume":"14","author":"Ouyang","year":"2025","journal-title":"Foods"},{"key":"10.1016\/j.ultsonch.2026.107795_b0210","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2023.106420","article-title":"Ultrasonic-assisted extraction, characteristics and activity of Ipomoea batatas polysaccharide","volume":"96","author":"Xiong","year":"2023","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.ultsonch.2026.107795_b0215","doi-asserted-by":"crossref","first-page":"492","DOI":"10.3390\/molecules31030492","article-title":"Optimization of extraction and antioxidant activities of resveratrol from polygonum cuspidatum by ultrasound-assisted natural deep eutectic solvent method","volume":"31","author":"Guo","year":"2026","journal-title":"Molecules"},{"key":"10.1016\/j.ultsonch.2026.107795_b0220","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1007\/s40974-024-00321-z","article-title":"Food wastes phenolic compounds (PCs): overview of contemporary greener extraction technologies, industrial potential, and its integration into circular bioeconomy","volume":"9","author":"Bhatia","year":"2024","journal-title":"Energy Ecol. Environ."}],"container-title":["Ultrasonics Sonochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S135041772600060X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S135041772600060X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,5,1]],"date-time":"2026-05-01T04:36:04Z","timestamp":1777610164000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S135041772600060X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,4]]},"references-count":44,"alternative-id":["S135041772600060X"],"URL":"https:\/\/doi.org\/10.1016\/j.ultsonch.2026.107795","relation":{},"ISSN":["1350-4177"],"issn-type":[{"value":"1350-4177","type":"print"}],"subject":[],"published":{"date-parts":[[2026,4]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"COSMO-RS guided screening of deep eutectic solvents and ultrasound-assisted extraction for resveratrol from Polygonum cuspidatum","name":"articletitle","label":"Article Title"},{"value":"Ultrasonics Sonochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ultsonch.2026.107795","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Authors. Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"107795"}}