{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T01:25:37Z","timestamp":1794533137271,"version":"4.9.1"},"reference-count":67,"publisher":"Elsevier BV","license":[{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T00:00:00Z","timestamp":1785542400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2026,6,14]],"date-time":"2026-06-14T00:00:00Z","timestamp":1781395200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Ultrasonics Sonochemistry"],"published-print":{"date-parts":[[2026,8]]},"DOI":"10.1016\/j.ultsonch.2026.107924","type":"journal-article","created":{"date-parts":[[2026,6,15]],"date-time":"2026-06-15T23:37:25Z","timestamp":1781566645000},"page":"107924","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":1,"special_numbering":"C","title":["Enhancement of content, purity and anti-myocardial ischemia\u2013reperfusion injury activity of persimmon leaf flavonoids: Ultrasonic-assisted extraction, purification and related mechanism"],"prefix":"10.1016","volume":"131","author":[{"given":"Liying","family":"Han","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qiang","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinnan","family":"Huo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chenxiao","family":"Guo","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuai","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yongrui","family":"Bao","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tianjiao","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi","family":"Zheng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanqiu","family":"Li","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bing","family":"Wang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiansheng","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.ultsonch.2026.107924_b0005","doi-asserted-by":"crossref","first-page":"1181","DOI":"10.1097\/CM9.0000000000004006","article-title":"Global burden of ischemic heart disease from 1990 to 2021: findings from the global burden of disease study 2021 and predictions to 2030","volume":"139","author":"Jing","year":"2026","journal-title":"Chin. Med. J."},{"key":"10.1016\/j.ultsonch.2026.107924_b0010","doi-asserted-by":"crossref","DOI":"10.1016\/j.ajpc.2026.101413","article-title":"The evolving burden of ischemic heart disease in China, 1990-2023: three decades of trends, risk factors, and future challenges","volume":"26","author":"Li","year":"2026","journal-title":"Am. J. Prev. Cardiol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0015","doi-asserted-by":"crossref","unstructured":"GBD 2023 Causes of Death Collaborators, Global burden of 292 causes of death in 204 countries and territories and 660 subnational locations, 1990-2023: a systematic analysis for the Global Burden of Disease Study 2023, Lancet. 406 (2025) 1811\u20131872, https:\/\/doi.org\/10.1016\/S0140-6736(25)01917-8.","DOI":"10.1016\/S0140-6736(25)01917-8"},{"key":"10.1016\/j.ultsonch.2026.107924_b0020","doi-asserted-by":"crossref","first-page":"695","DOI":"10.1007\/s11010-025-05440-7","article-title":"Cell death forms in myocardial ischemia-reperfusion injury and their potential clinical applications","volume":"481","author":"Xu","year":"2026","journal-title":"Mol. Cell. Biochem."},{"key":"10.1016\/j.ultsonch.2026.107924_b0025","doi-asserted-by":"crossref","first-page":"326","DOI":"10.1007\/s11239-025-03176-1","article-title":"Efficacy of sonothrombolysis as an adjunct to primary percutaneous coronary intervention in ST-segment elevation myocardial infarction: a systematic review and meta-analysis","volume":"59","author":"Abo Zeid","year":"2026","journal-title":"J. Thromb. Thrombolysis"},{"key":"10.1016\/j.ultsonch.2026.107924_b0030","doi-asserted-by":"crossref","unstructured":"A. Kishore Jain, N. Gozum, S. Wong, B. E. Nolan, K. M. Clare, E. Feldstein, S. Vazquez, B. Russo, A. Thomas, A. Lui, M. Pandit, G. Kaur, C. Medicherla, C. D. Gandhi, F. Al-Mufti, Treatment and Outcomes for Acute Ischemic Stroke in Cardiomyopathy Patients With Heart Failure: A Retrospective Cross-Sectional Study, Cardiol. Rev. (2026) Advance online publication. https:\/\/doi.org\/10.1097\/CRD.0000000000001222.","DOI":"10.1097\/CRD.0000000000001222"},{"key":"10.1016\/j.ultsonch.2026.107924_b0035","doi-asserted-by":"crossref","DOI":"10.1016\/j.pharmthera.2026.109026","article-title":"Innate immune responses following myocardial ischemia and reperfusion: evidence, mechanisms, and translational challenges","volume":"282","author":"Zhang","year":"2026","journal-title":"Pharmacol. Ther."},{"key":"10.1016\/j.ultsonch.2026.107924_b0040","doi-asserted-by":"crossref","first-page":"4949","DOI":"10.1007\/s00210-025-04622-w","article-title":"The effect of Edaravone on acute ischemic stroke, large vessel occlusion, not treated with intravenous thrombolytic, and endovascular thrombectomy: a double-blind placebo-controlled trial","volume":"399","author":"Razmeh","year":"2026","journal-title":"Naunyn Schmiedebergs Arch. Pharmacol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0045","doi-asserted-by":"crossref","first-page":"809","DOI":"10.1007\/s10557-025-07761-7","article-title":"P, Zhang, comment on: \u201cmoderate-intensity atorvastatin and ezetimibe combination therapy versus high-intensity atorvastatin in patients with angina pectoris who underwent percutaneous coronary intervention\u201d","volume":"40","author":"Huang","year":"2026","journal-title":"Cardiovasc. Drugs Ther."},{"key":"10.1016\/j.ultsonch.2026.107924_b0050","doi-asserted-by":"crossref","first-page":"341","DOI":"10.4103\/0022-3859.90091","article-title":"Amlodipine-induced petechial rash","volume":"57","author":"Murthy","year":"2011","journal-title":"J. Postgrad. Med."},{"key":"10.1016\/j.ultsonch.2026.107924_b0055","doi-asserted-by":"crossref","DOI":"10.1002\/brb3.70158","article-title":"Edaravone's Safety Profile in Acute Ischemic Stroke","volume":"14","author":"Batino","year":"2024","journal-title":"Brain Behav."},{"key":"10.1016\/j.ultsonch.2026.107924_b0060","doi-asserted-by":"crossref","DOI":"10.1016\/j.vph.2024.107378","article-title":"Molecular mechanisms of flavonoids in myocardial ischemia reperfusion injury: evidence from in-vitro and in-vivo studies","volume":"155","author":"Sharma","year":"2024","journal-title":"Vascul. Pharmacol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0065","article-title":"A systematic review and meta-analysis of phytoestrogen protects against myocardial ischemia\/reperfusion injury: pre-clinical evidence from small animal studies","volume":"13","author":"Wang","year":"2022","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0070","article-title":"Cardioprotective effects of puerarin against myocardial ischemia-reperfusion injury: a preclinical systematic review and meta-analysis","volume":"17","author":"Chen","year":"2026","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0075","doi-asserted-by":"crossref","DOI":"10.1016\/j.steroids.2025.109637","article-title":"Roles of equol and the PI3K\/Akt signaling pathway in the cardioprotective effects of enteral daidzein against ischemia-reperfusion injury in isolated rat hearts","volume":"220","author":"Yamada","year":"2025","journal-title":"Steroids"},{"key":"10.1016\/j.ultsonch.2026.107924_b0080","doi-asserted-by":"crossref","DOI":"10.3389\/fimmu.2023.1248056","article-title":"Low-intensity pulsed ultrasound of different intensities differently affects myocardial ischemia\/reperfusion injury by modulating cardiac oxidative stress and inflammatory reaction","volume":"14","author":"Cao","year":"2023","journal-title":"Front. Immunol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0085","doi-asserted-by":"crossref","first-page":"329","DOI":"10.1253\/circj.CJ-25-0926","article-title":"Resorcimoline protects against myocardial ischemia-reperfusion injury via suppression of oxidative stress","volume":"90","author":"Ueno","year":"2026","journal-title":"Circ J"},{"key":"10.1016\/j.ultsonch.2026.107924_b0090","doi-asserted-by":"crossref","unstructured":"D. M. U. M. Dissanayake, W. K. M. Omeka, B. P. M. Vileka Jayamali, H. M. V. Udayantha, W. A. D. L. R. Warnakula, W. P. S. N. Wijeweera, U. P. E. Arachchi, A. Kalaichelvan, S. Jung, Q. Wan, J. Lee, Expression profiling and functional investigation of peroxiredoxin 2 in Chub mackerel: Multifunctional roles in oxidative stress regulation, apoptosis, and immune modulation, Dev. Comp. Immunol. 176 (2026) 105553, https:\/\/doi.org\/10.1016\/j.dci.2026.105553.","DOI":"10.1016\/j.dci.2026.105553"},{"key":"10.1016\/j.ultsonch.2026.107924_b0095","doi-asserted-by":"crossref","first-page":"840","DOI":"10.3390\/ph15070840","article-title":"Short-term administration of lemon balm extract ameliorates myocardial ischemia\/reperfusion injury: focus on oxidative stress","volume":"15","author":"Draginic","year":"2022","journal-title":"Pharmaceuticals"},{"key":"10.1016\/j.ultsonch.2026.107924_b0100","doi-asserted-by":"crossref","first-page":"937","DOI":"10.3390\/plants12040937","article-title":"Persimmon leaves: nutritional pharmaceutical, and industrial potential-a review","volume":"12","author":"Hossain","year":"2023","journal-title":"Plants"},{"key":"10.1016\/j.ultsonch.2026.107924_b0105","doi-asserted-by":"crossref","DOI":"10.1002\/cbdv.71364","article-title":"An integrated pharmacological evaluation and GC-MS\/MS-guided metabolite profiling of diospyros sylvatica roxb. leaves revealing analgesic, antioxidant, and antidiabetic activities","volume":"23","author":"Afrose","year":"2026","journal-title":"Chem. Biodivers."},{"key":"10.1016\/j.ultsonch.2026.107924_b0110","doi-asserted-by":"crossref","unstructured":"T. Bin Emran, M. A. Amin, B. Sutradhar, S. H. Sweilam, T. S. Shanmugarajan, U. V. N. V. Arjun, A. Durairaj, P. G. Mahesh, M. I. Jebastine, P. D. Prasad, M. Suliman, M. Zia Uddin, A Comprehensive Review of the Phytochemical Constituents and Diverse Pharmacological Applications of Diospyros kaki (Persimmon) Across Traditional and Modern Medicine, Curr. Top. Med. Chem. (2026) Advance online publication, https:\/\/doi.org\/10.2174\/0115680266412103251206082207.","DOI":"10.2174\/0115680266412103251206082207"},{"key":"10.1016\/j.ultsonch.2026.107924_b0115","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1186\/s13020-022-00609-4","article-title":"Persimmon leaf extract alleviates chronic social defeat stress-induced depressive-like behaviors by preventing dendritic spine loss via inhibition of serotonin reuptake in mice","volume":"17","author":"Yu","year":"2022","journal-title":"Chin. Med."},{"key":"10.1016\/j.ultsonch.2026.107924_b0120","doi-asserted-by":"crossref","first-page":"210","DOI":"10.1016\/j.cbi.2017.07.026","article-title":"Flavonoids from persimmon (Diospyros kaki L.) leaves inhibit proliferation and induce apoptosis in PC-3 cells by activation of oxidative stress and mitochondrial apoptosis","volume":"275","author":"Ding","year":"2017","journal-title":"Chem. Biol. Interact."},{"key":"10.1016\/j.ultsonch.2026.107924_b0125","first-page":"417","article-title":"Efficacy of phospholipid complex of flavonoids from persimmon leaves on atherosclerosis, and possible mechanism","volume":"42","author":"Jinpeng","year":"2022","journal-title":"J. Tradit. Chin. Med."},{"key":"10.1016\/j.ultsonch.2026.107924_b0130","doi-asserted-by":"crossref","first-page":"715","DOI":"10.1089\/jmf.2014.3307","article-title":"Ethanol extract of persimmon tree leaves improves blood circulation and lipid metabolism in rats fed a high-fat diet","volume":"18","author":"Ryu","year":"2015","journal-title":"J. Med. Food"},{"key":"10.1016\/j.ultsonch.2026.107924_b0135","doi-asserted-by":"crossref","first-page":"229","DOI":"10.1016\/j.jep.2015.01.007","article-title":"Persimmon (Diospyros kaki L.) leaves: a review on traditional uses, phytochemistry and pharmacological properties","volume":"163","author":"Xie","year":"2015","journal-title":"J. Ethnopharmacol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0140","article-title":"Harnessing nature: the role of medicinal plants in alleviating cisplatin toxicity","volume":"45","author":"Abdelhiee","year":"2025","journal-title":"Pak. Vet. J."},{"key":"10.1016\/j.ultsonch.2026.107924_b0145","first-page":"4214","article-title":"Research progress of flavonoids and extraction processes in persimmon leaves","volume":"53","author":"Wang","year":"2022","journal-title":"Chin. Tradit. Herbal Drugs"},{"key":"10.1016\/j.ultsonch.2026.107924_b0150","doi-asserted-by":"crossref","unstructured":"I. Qadeer, H. K. W. Aslam, M. Tayyib, Hasddin, Q. Ali, 2025. Ultrasound Applications in Bioactive Peel Compounds: Enhancing Gut, Food, and Plant Health, J. Glob. Innov. Agric. Sci. 13 (2025) 1245-1256, https:\/\/doi.org\/10.22194\/JGIAS\/25.1891.","DOI":"10.22194\/JGIAS\/25.1891"},{"key":"10.1016\/j.ultsonch.2026.107924_b0155","first-page":"723","article-title":"Anticancer and antioxidant activities of polyphenolic pomegranate peel extracts obtained by a novel hybrid ultrasound-microwave method: in vitro and in vivo studies in albino mice with HeLa, colon, and HepG2 cancerous cell lines","volume":"45","author":"Altarjami","year":"2025","journal-title":"Pak Vet J"},{"key":"10.1016\/j.ultsonch.2026.107924_b0160","doi-asserted-by":"crossref","first-page":"1567","DOI":"10.1039\/D4AY01885K","article-title":"Eco-friendly extraction and recovery of triterpenoids from persimmon leaves (Diospyros kaki L.f.) using ultrasound-assisted deep eutectic solvents and macroporous resins","volume":"17","author":"Le","year":"2025","journal-title":"Anal. Methods"},{"key":"10.1016\/j.ultsonch.2026.107924_b0165","doi-asserted-by":"crossref","first-page":"2689","DOI":"10.1016\/j.fct.2011.07.042","article-title":"Evaluation to the antioxidant activity of total flavonoids extract from persimmon (Diospyros kaki L.) leaves","volume":"49","author":"Sun","year":"2011","journal-title":"Food Chem. Toxicol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0170","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2024.107164","article-title":"Study on optimization of extraction and purification processes for total flavonoids from Lycopi herba roots and their anti-proliferative effects on fibrous synoviocytes in human rheumatoid arthritis","volume":"112","author":"Chen","year":"2025","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.ultsonch.2026.107924_b0175","doi-asserted-by":"crossref","DOI":"10.1016\/j.ultsonch.2024.107079","article-title":"Ultrasound-assisted extraction, optimization, and purification of total flavonoids from Daphnegenkwa and analysis of their antioxidant, anti-inflammatory, and analgesic activities","volume":"111","author":"Xiang","year":"2024","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.ultsonch.2026.107924_b0180","doi-asserted-by":"crossref","first-page":"84","DOI":"10.3390\/separations12040084","article-title":"Adsorption and desorption characteristics of simiao yong'an decoction on macroporous adsorption resins","volume":"12","author":"Jiao","year":"2025","journal-title":"Separations"},{"key":"10.1016\/j.ultsonch.2026.107924_b0185","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1007\/s11694-024-02727-z","article-title":"Adsorption\/desorption behavior and purification process optimization of theaflavins on macroporous resin","volume":"18","author":"Han","year":"2024","journal-title":"J. Food Meas. Charact."},{"key":"10.1016\/j.ultsonch.2026.107924_b0190","doi-asserted-by":"crossref","first-page":"1060","DOI":"10.1080\/10826068.2022.2028636","article-title":"Ultrasound-assisted aqueous two-phase extraction of total flavonoids from Tremella fuciformis and antioxidant activity of extracted flavonoids","volume":"52","author":"Ji","year":"2022","journal-title":"Prep. Biochem. Biotechnol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0195","doi-asserted-by":"crossref","first-page":"6797","DOI":"10.3390\/ijms25126797","article-title":"The Role of TPM3 in Protecting Cardiomyocyte from Hypoxia-Induced Injury via Cytoskeleton Stabilization","volume":"25","author":"Huang","year":"2024","journal-title":"Int. J. Mol. Sci."},{"key":"10.1016\/j.ultsonch.2026.107924_b0200","doi-asserted-by":"crossref","unstructured":"R. Singh, R. Kishor, V. Singh, V. Singh, P. Prasad, N.S. Aulakh, U.K. Tiwari, B. Kumar, Radio-frequency (RF) room temperature plasma treatment of sweet basil seeds (Ocimum basilicum L.) for germination potential enhancement by immaculation, J. Appl. Res. Med. Aromat. Plants. 26 (2022) 100350, https:\/\/doi.org\/10.1016\/j.jarmap.2021.100350.","DOI":"10.1016\/j.jarmap.2021.100350"},{"key":"10.1016\/j.ultsonch.2026.107924_b0205","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155993","article-title":"Longxuetongluo Capsule alleviate ischemia\/reperfusion induced cardiomyocyte apoptosis through modulating oxidative stress and mitochondrial dysfunction","volume":"134","author":"Yang","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.ultsonch.2026.107924_b0210","doi-asserted-by":"crossref","unstructured":"M. Tourabi, K. Faiz, R. Ezzouggari, B. Louast\u00e9, M. Merzouki, M. Dauelbait, M. Bourhia, K. S. Almaary, F. Siddique, B. Lyoussi, E. Derwich, Optimization of extraction process and solvent polarities to enhance the recovery of phytochemical compounds, nutritional content, and biofunctional properties of Mentha longifolia L. extracts, Bioresour. Bioprocess. 12 (2025) 24, https:\/\/doi.org\/10.1186\/s40643-025-00859-8.","DOI":"10.1186\/s40643-025-00910-8"},{"key":"10.1016\/j.ultsonch.2026.107924_b0215","doi-asserted-by":"crossref","first-page":"174","DOI":"10.1002\/fsn3.91","article-title":"Study to find the best extraction solvent for use with guava leaves (Psidium guajava L.) for high antioxidant efficacy","volume":"2","author":"Seo","year":"2014","journal-title":"Food Sci. Nutr."},{"key":"10.1016\/j.ultsonch.2026.107924_b0220","doi-asserted-by":"crossref","first-page":"538","DOI":"10.1016\/j.ultsonch.2018.07.018","article-title":"Advances in ultrasound assisted extraction of bioactive compounds from cash crops - a review","volume":"48","author":"Wen","year":"2018","journal-title":"Ultrason. Sonochem."},{"key":"10.1016\/j.ultsonch.2026.107924_b0225","doi-asserted-by":"crossref","first-page":"8","DOI":"10.1016\/j.indcrop.2023.117544","article-title":"Solid-liquid extraction of chlorogenic acid from eucommia ulmoides oliver leaves: kinetic and mass transfer studies","volume":"205","author":"Shen","year":"2023","journal-title":"Ind. Crops Prod."},{"key":"10.1016\/j.ultsonch.2026.107924_b0230","doi-asserted-by":"crossref","first-page":"3031","DOI":"10.3390\/molecules30143031","article-title":"Comparison of Ultrasound-Microwave-Assisted and Hot Reflux Extractions of Polysaccharides from Alpinia officinarum Hance: optimization Characterization, and Antioxidant Activity","volume":"30","author":"Tang","year":"2025","journal-title":"Molecules"},{"issue":"18","key":"10.1016\/j.ultsonch.2026.107924_b0235","doi-asserted-by":"crossref","first-page":"2083","DOI":"10.1007\/s11947-024-03574-y","article-title":"Recent advancements in microwave-assisted extraction of flavonoids: a review","volume":"2025","author":"Wang","year":"2025","journal-title":"Food Bioproc. Tech."},{"key":"10.1016\/j.ultsonch.2026.107924_b0240","doi-asserted-by":"crossref","first-page":"3941","DOI":"10.3390\/foods14223941","article-title":"Bioactive flavonoids from paulownia tomentosa flowers: extraction optimization and \u03b1-glucosidase inhibitory kinetics","volume":"14","author":"Jiang","year":"2025","journal-title":"Foods"},{"key":"10.1016\/j.ultsonch.2026.107924_b0245","doi-asserted-by":"crossref","DOI":"10.1016\/j.chroma.2021.462211","article-title":"Cooperative adsorption of L-tryptophan and sodium ion on a hyper-cross-linked resin: experimental studies and mathematical modeling","volume":"1648","author":"Jiao","year":"2021","journal-title":"J. Chromatogr. A"},{"key":"10.1016\/j.ultsonch.2026.107924_b0250","doi-asserted-by":"crossref","DOI":"10.1002\/jssc.202400372","article-title":"Macroporous polymeric resin for the purification of flavonoids from medicinal plants: a review","volume":"47","author":"Aljawarneh","year":"2024","journal-title":"J. Sep. Sci."},{"key":"10.1016\/j.ultsonch.2026.107924_b0255","doi-asserted-by":"crossref","first-page":"76","DOI":"10.1016\/j.ijbiomac.2019.03.207","article-title":"Optimized purification process of polysaccharides from Carex meyeriana Kunth by macroporous resin, its characterization and immunomodulatory activity","volume":"132","author":"Hu","year":"2019","journal-title":"Int. J. Biol. Macromol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0260","doi-asserted-by":"crossref","first-page":"7273","DOI":"10.3390\/molecules28217273","article-title":"Study on Purification, Identification and Antioxidant of Flavonoids Extracted from Perilla leaves","volume":"28","author":"Li","year":"2023","journal-title":"Molecules"},{"key":"10.1016\/j.ultsonch.2026.107924_b0265","doi-asserted-by":"crossref","unstructured":"J. Yang, T. Huang, L. Xia, J. Li, Artemisia absinthium L. Extract Targeting the JAK2\/STAT3 Pathway to Ameliorate Atherosclerosis, Foods 14 (2025) 2381, https:\/\/doi.org\/10.3390\/foods14132381.","DOI":"10.3390\/foods14132381"},{"key":"10.1016\/j.ultsonch.2026.107924_b0270","doi-asserted-by":"crossref","DOI":"10.3389\/fphar.2025.1572678","article-title":"Persimmon leaf extract in dyslipidemia: a systematic review and meta-analysis","volume":"16","author":"Dong","year":"2025","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0275","doi-asserted-by":"crossref","first-page":"2545","DOI":"10.1002\/ptr.6985","article-title":"Persimmon leaf extract protects mice from atopic dermatitis by inhibiting T cell activation via regulation of the JNK pathway","volume":"35","author":"Lee","year":"2021","journal-title":"Phytother. Res."},{"key":"10.1016\/j.ultsonch.2026.107924_b0280","doi-asserted-by":"crossref","first-page":"4196","DOI":"10.1002\/ptr.7900","article-title":"Hyperoside prevents doxorubicin-induced cardiotoxicity by inhibiting NOXs\/ROS\/NLRP3 inflammasome signaling pathway","volume":"37","author":"Wei","year":"2023","journal-title":"Phytother. Res."},{"key":"10.1016\/j.ultsonch.2026.107924_b0285","doi-asserted-by":"crossref","first-page":"5553","DOI":"10.2147\/DDDT.S535517","article-title":"Mechanistic insights into flavonoid subclasses as cardioprotective agents against doxorubicin-induced cardiotoxicity: a comprehensive review","volume":"19","author":"Shang","year":"2025","journal-title":"Drug Des. Devel. Ther."},{"key":"10.1016\/j.ultsonch.2026.107924_b0290","article-title":"Isoquercitrin alleviates pirarubicin-induced cardiotoxicity in vivo and in vitro by inhibiting apoptosis through Phlpp1\/AKT\/Bcl-2 signaling pathway","volume":"15","author":"Wang","year":"2024","journal-title":"Front. Pharmacol."},{"key":"10.1016\/j.ultsonch.2026.107924_b0295","doi-asserted-by":"crossref","first-page":"2455","DOI":"10.1007\/s12013-024-01355-0","article-title":"Isoquercitrin alleviates OGD\/R-induced oxidative stress and impaired mitochondrial biogenesis in SH-SY5Y cells via the NRF1\/TFAM pathway","volume":"82","author":"Li","year":"2024","journal-title":"Cell Biochem. Biophys."},{"key":"10.1016\/j.ultsonch.2026.107924_b0300","doi-asserted-by":"crossref","DOI":"10.1155\/2015\/481405","article-title":"Protective effects of kaempferol against myocardial ischemia\/reperfusion injury in isolated rat heart via antioxidant activity and inhibition of glycogen synthase kinase-3\u03b2","volume":"2015","author":"Zhou","year":"2015","journal-title":"Oxid. Med. Cell. Longev."},{"key":"10.1016\/j.ultsonch.2026.107924_b0305","doi-asserted-by":"crossref","first-page":"6011","DOI":"10.1021\/jf200940h","article-title":"Isolation and tyrosinase inhibitory effects of polyphenols from the leaves of persimmon, Diospyros kaki","volume":"59","author":"Xue","year":"2011","journal-title":"J. Agric. Food Chem."},{"key":"10.1016\/j.ultsonch.2026.107924_b0310","doi-asserted-by":"crossref","first-page":"859","DOI":"10.3390\/antiox13070859","article-title":"Astragalin from thesium chinense: a novel anti-aging and antioxidant agent targeting IGFR\/CD38\/sirtuins","volume":"13","author":"Wang","year":"2024","journal-title":"Antioxidants"},{"key":"10.1016\/j.ultsonch.2026.107924_b0315","doi-asserted-by":"crossref","DOI":"10.1016\/j.phymed.2024.155649","article-title":"The pathological mechanisms and potential therapeutic drugs for myocardial ischemia reperfusion injury","volume":"129","author":"Zhang","year":"2024","journal-title":"Phytomedicine"},{"key":"10.1016\/j.ultsonch.2026.107924_b0320","doi-asserted-by":"crossref","first-page":"762","DOI":"10.1007\/s12265-025-10628-9","article-title":"Hypoxia\/reoxygenation-induced glycolysis mediates myocardial ischemia-reperfusion injury through promoting the lactylation of GPX4","volume":"18","author":"Wang","year":"2025","journal-title":"J. Cardiovasc. Transl. Res."},{"key":"10.1016\/j.ultsonch.2026.107924_b0325","doi-asserted-by":"crossref","unstructured":"A. A. Abro, J. Tabusam, M. Abbas, S. Khalid, Q. Liu, K. Abbas, Z. Jie, Y. Xu, Y. Hou, Z. Zhou, X. Cai, F. Liu, Multi-omics insights into antioxidant defense, phenylpropanoid, and flavonoid pathways governing cold stress tolerance in cotton (Gossypium hirsutum), Plant (2026) Advance online publication, https:\/\/doi.org\/10.1016\/j.plaphy.2026.111415.","DOI":"10.1016\/j.plaphy.2026.111415"},{"key":"10.1016\/j.ultsonch.2026.107924_b0330","doi-asserted-by":"crossref","first-page":"933","DOI":"10.1002\/jbm.b.35203","article-title":"Human hair proteins as natural reactive oxygen species scavengers for in vitro applications","volume":"111","author":"Lai","year":"2023","journal-title":"J. Biomed. Mater. Res. B Appl. Biomater."},{"key":"10.1016\/j.ultsonch.2026.107924_b0335","doi-asserted-by":"crossref","first-page":"3932","DOI":"10.1158\/0008-5472.CAN-10-3425","article-title":"Erlotinib-mediated inhibition of EGFR signaling induces metabolic oxidative stress through NOX4","volume":"71","author":"Orcutt","year":"2011","journal-title":"Cancer Res."}],"container-title":["Ultrasonics Sonochemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1350417726001896?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S1350417726001896?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T00:25:34Z","timestamp":1794529534000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S1350417726001896"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,8]]},"references-count":67,"alternative-id":["S1350417726001896"],"URL":"https:\/\/doi.org\/10.1016\/j.ultsonch.2026.107924","relation":{},"ISSN":["1350-4177"],"issn-type":[{"value":"1350-4177","type":"print"}],"subject":[],"published":{"date-parts":[[2026,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Enhancement of content, purity and anti-myocardial ischemia\u2013reperfusion injury activity of persimmon leaf flavonoids: Ultrasonic-assisted extraction, purification and related mechanism","name":"articletitle","label":"Article Title"},{"value":"Ultrasonics Sonochemistry","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.ultsonch.2026.107924","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"\u00a9 2026 The Author(s). Published by Elsevier B.V.","name":"copyright","label":"Copyright"}],"article-number":"107924"}}