{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,30]],"date-time":"2026-04-30T04:52:10Z","timestamp":1777524730977,"version":"3.51.4"},"reference-count":28,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2005,12,1]],"date-time":"2005-12-01T00:00:00Z","timestamp":1133395200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urology"],"published-print":{"date-parts":[[2005,12]]},"DOI":"10.1016\/j.urology.2005.06.077","type":"journal-article","created":{"date-parts":[[2005,12,22]],"date-time":"2005-12-22T18:48:05Z","timestamp":1135277285000},"page":"1234-1238","source":"Crossref","is-referenced-by-count":17,"title":["Effect of prostatic massage on serum complexed prostate-specific antigen levels"],"prefix":"10.1016","volume":"66","author":[{"given":"Fatih","family":"Tarhan","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asuman","family":"Or\u00e7un","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u0130nci","family":"K\u00fc\u00e7\u00fckercan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nazan","family":"\u00c7amursoy","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"U\u011fur","family":"Kuyumcuo\u011flu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2005.06.077_bib1","first-page":"159","article-title":"Purification of a human prostate-specific antigen","volume":"17","author":"Wang","year":"1979","journal-title":"Invest Urol"},{"key":"10.1016\/j.urology.2005.06.077_bib2","first-page":"221","article-title":"A guide to the interpretation of serum prostate specific antigen levels","volume":"28","author":"Bunting","year":"1995","journal-title":"Clin Chem"},{"key":"10.1016\/j.urology.2005.06.077_bib3","doi-asserted-by":"crossref","first-page":"293","DOI":"10.1016\/S0094-0143(05)70375-X","article-title":"The effects of prostatic manipulation on prostatic-specific antigen levels","volume":"24","author":"Klein","year":"1997","journal-title":"Urol Clin North Am"},{"key":"10.1016\/j.urology.2005.06.077_bib4","first-page":"1110","article-title":"The effect of digital rectal examination on serum levels of prostate-specific antigen","volume":"112","author":"Brawer","year":"1988","journal-title":"Arch Pathol Lab Med"},{"key":"10.1016\/j.urology.2005.06.077_bib5","doi-asserted-by":"crossref","first-page":"83","DOI":"10.1016\/S0022-5347(17)36517-5","article-title":"The effect of digital rectal examination on the serum levels of prostate-specific antigen concentration","volume":"148","author":"Chybowski","year":"1992","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2005.06.077_bib6","doi-asserted-by":"crossref","first-page":"2227","DOI":"10.1001\/jama.1992.03480160085039","article-title":"The effect of digital rectal examination on PSA levels","volume":"267","author":"Crawford","year":"1992","journal-title":"JAMA"},{"key":"10.1016\/j.urology.2005.06.077_bib7","doi-asserted-by":"crossref","first-page":"1744","DOI":"10.1016\/S0022-5347(01)64849-3","article-title":"The effect of digital rectal examination, flexible cystoscopy and prostatic biopsy on free and total prostate specific antigen, and the free-to-total prostate specific antigen ratio in clinical practice","volume":"157","author":"Collins","year":"1997","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2005.06.077_bib8","doi-asserted-by":"crossref","first-page":"403","DOI":"10.1159\/000473787","article-title":"Short-term effect of digital rectal examination on serum prostate-specific antigen levels","volume":"29","author":"\u00c7evik","year":"1996","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2005.06.077_bib9","doi-asserted-by":"crossref","first-page":"65","DOI":"10.1046\/j.1464-410x.2000.00709.x","article-title":"Prostatic manipulation has a minimal effect on complexed prostate-specific antigen levels","volume":"86","author":"Lynn","year":"2000","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2005.06.077_bib10","doi-asserted-by":"crossref","first-page":"857","DOI":"10.1016\/S0090-4295(99)00239-3","article-title":"Effect of digital rectal examination on serum complexed and free prostatic-specific antigen and percentage of free prostate-specific antigen","volume":"54","author":"Lechevallier","year":"1999","journal-title":"Urology"},{"key":"10.1016\/j.urology.2005.06.077_bib11","doi-asserted-by":"crossref","first-page":"186","DOI":"10.1159\/000282670","article-title":"Influence of digital examination, cystoscopy, transrectal ultrasonography and needle biopsy on the concentration of prostate-specific antigen","volume":"53","author":"Deliveliotis","year":"1994","journal-title":"Urol Int"},{"key":"10.1016\/j.urology.2005.06.077_bib12","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1177\/172460080201700302","article-title":"The impact of intraoperative manipulation of the prostate on total and free prostate-specific antigen","volume":"17","author":"Oberpenning","year":"2002","journal-title":"Int J Biol Markers"},{"key":"10.1016\/j.urology.2005.06.077_bib13","doi-asserted-by":"crossref","first-page":"810","DOI":"10.1016\/S0022-5347(17)37392-5","article-title":"Effects of rectal examination, prostatic massage, ultrasonography and needle biopsy on serum prostate specific antigen levels","volume":"147","author":"Yuan","year":"1992","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2005.06.077_bib14","first-page":"1097","article-title":"Effects of prostatic massage on serum levels of prostatic acid phosphatase and specific antigen","volume":"79","author":"Sahin","year":"1992","journal-title":"Bull Cancer"},{"key":"10.1016\/j.urology.2005.06.077_bib15","doi-asserted-by":"crossref","first-page":"906","DOI":"10.1056\/NEJM198710083171501","article-title":"Prostate specific antigen as a serum marker for adenocarcinoma of the prostate","volume":"317","author":"Stamey","year":"1987","journal-title":"N Engl J Med"},{"key":"10.1016\/j.urology.2005.06.077_bib16","doi-asserted-by":"crossref","first-page":"682","DOI":"10.1016\/0959-8049(95)00016-C","article-title":"Kinetics of prostate-specific antigen after manipulation of the prostate","volume":"31A","author":"Bossens","year":"1995","journal-title":"Eur J Cancer"},{"key":"10.1016\/j.urology.2005.06.077_bib17","doi-asserted-by":"crossref","first-page":"1452","DOI":"10.1001\/jama.1997.03540420048028","article-title":"Prostate cancer detection in men with serum PSA concentrations of 2.6 to 4.0 ng\/mL and benign prostate examination","volume":"277","author":"Catalona","year":"1997","journal-title":"JAMA"},{"key":"10.1016\/j.urology.2005.06.077_bib18","doi-asserted-by":"crossref","first-page":"1930","DOI":"10.1016\/S0022-5347(05)66245-3","article-title":"Can complexed prostate specific antigen and prostatic volume enhance prostate cancer detection in men with total prostate specific antigen between 2.5 and 4.0 ng.\/ml","volume":"165","author":"Okihara","year":"2001","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2005.06.077_bib19","doi-asserted-by":"crossref","first-page":"1542","DOI":"10.1001\/jama.279.19.1542","article-title":"Use of percentage of free prostate specific antigen to enhance differentiation of prostate cancer from benign prostatic disease","volume":"279","author":"Catalona","year":"1998","journal-title":"JAMA"},{"key":"10.1016\/j.urology.2005.06.077_bib20","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1016\/0090-4295(90)80023-G","article-title":"Serum prostate-specific antigen","volume":"35","author":"El-Shirbiny","year":"1990","journal-title":"Urology"},{"key":"10.1016\/j.urology.2005.06.077_bib21","doi-asserted-by":"crossref","first-page":"20","DOI":"10.1159\/000474716","article-title":"Influence of prostatic disease and prostatic manipulations on the concentration of prostate specific antigen","volume":"22","author":"Walz","year":"1992","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2005.06.077_bib22","doi-asserted-by":"crossref","first-page":"255","DOI":"10.1159\/000019577","article-title":"Effect of digital rectal examination and flexible cystoscopy on free and total prostatic-specific antigen and percentage of free prostate-specific antigen","volume":"33","author":"Rodriguez-Rubio","year":"1998","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2005.06.077_bib23","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1016\/S0090-4295(98)00208-8","article-title":"Determination of the site of metabolism of total, free and complexed prostate-specific antigen","volume":"52","author":"K\u0131l\u0131\u00e7","year":"1998","journal-title":"Urology"},{"key":"10.1016\/j.urology.2005.06.077_bib24","doi-asserted-by":"crossref","first-page":"1099","DOI":"10.1016\/S0022-5347(01)66399-7","article-title":"Complex formation between PSA isoenzymes and protease inhibitors","volume":"155","author":"Leinonen","year":"1996","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2005.06.077_bib25","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1002\/pros.2990250206","article-title":"Relationship between serum prostate-specific antigen and histological prostatitis in patients with benign prostatic hyperplasia","volume":"25","author":"Hasui","year":"1994","journal-title":"Prostate"},{"key":"10.1016\/j.urology.2005.06.077_bib26","doi-asserted-by":"crossref","first-page":"407","DOI":"10.1016\/S0022-5347(01)67064-2","article-title":"Effect of inflammation and benign prostatic hyperplasia on elevated serum prostate-specific antigen levels","volume":"154","author":"Nadler","year":"1995","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2005.06.077_bib27","doi-asserted-by":"crossref","first-page":"93","DOI":"10.1046\/j.1525-1411.1999.09919.x","article-title":"A critical evaluation of prostate specific antigen parameter responses to manipulation according to prostatic histology","volume":"1","author":"Alexandrou","year":"1999","journal-title":"Prostate J"},{"key":"10.1016\/j.urology.2005.06.077_bib28","doi-asserted-by":"crossref","first-page":"427","DOI":"10.1016\/0090-4295(94)90225-9","article-title":"Alpha1-antichymotrypsin production in PSA-producing cells is common in prostate cancer but rare in benign prostatic hyperplasia","volume":"43","author":"Bjork","year":"1994","journal-title":"Urology"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429505008952?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429505008952?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,4,12]],"date-time":"2019-04-12T02:45:25Z","timestamp":1555037125000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429505008952"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2005,12]]},"references-count":28,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2005,12]]}},"alternative-id":["S0090429505008952"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2005.06.077","relation":{},"ISSN":["0090-4295"],"issn-type":[{"value":"0090-4295","type":"print"}],"subject":[],"published":{"date-parts":[[2005,12]]}}}