{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,1]],"date-time":"2026-06-01T18:49:00Z","timestamp":1780339740329,"version":"3.54.1"},"reference-count":24,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2007,2,1]],"date-time":"2007-02-01T00:00:00Z","timestamp":1170288000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urology"],"published-print":{"date-parts":[[2007,2]]},"DOI":"10.1016\/j.urology.2006.12.018","type":"journal-article","created":{"date-parts":[[2007,2,22]],"date-time":"2007-02-22T09:28:35Z","timestamp":1172136515000},"page":"407-411","source":"Crossref","is-referenced-by-count":40,"title":["Using Caveolin-1 Knockout Mouse to Study Impaired Detrusor Contractility and Disrupted Muscarinic Activity in the Aging Bladder"],"prefix":"10.1016","volume":"69","author":[{"given":"H. Henry","family":"Lai","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy B.","family":"Boone","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy C.","family":"Thompson","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher P.","family":"Smith","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George T.","family":"Somogyi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2006.12.018_bib1","doi-asserted-by":"crossref","first-page":"3076","DOI":"10.1001\/jama.257.22.3076","article-title":"Detrusor hyperactivity with impaired contractile function: an unrecognized but common cause of incontinence in elderly patients","volume":"257","author":"Resnick","year":"1987","journal-title":"JAMA"},{"key":"10.1016\/j.urology.2006.12.018_bib2","doi-asserted-by":"crossref","first-page":"1887","DOI":"10.1097\/01.ju.0000176740.76061.24","article-title":"The natural history of lower urinary tract dysfunction in men: minimum 10-year urodynamic followup of transurethral resection of prostate for bladder outlet obstruction","volume":"174","author":"Thomas","year":"2005","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2006.12.018_bib3","doi-asserted-by":"crossref","first-page":"720","DOI":"10.1016\/S0022-5347(17)51423-8","article-title":"Critical evaluation of the Crede maneuver: a urodynamic study of 207 patients","volume":"130","author":"Barbalias","year":"1983","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2006.12.018_bib4","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1016\/S0022-5347(17)61055-3","article-title":"Clean, intermittent self-catheterization in the treatment of urinary tract disease","volume":"107","author":"Lapides","year":"1972","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2006.12.018_bib5","doi-asserted-by":"crossref","first-page":"455","DOI":"10.1016\/0090-4295(76)90274-0","article-title":"Bethanechol chloride in neurogenic bladder dysfunction","volume":"8","author":"Diokno","year":"1976","journal-title":"Urology"},{"key":"10.1016\/j.urology.2006.12.018_bib6","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1016\/S0022-5347(17)47234-X","article-title":"Is bethanechol chloride clinically effective in promoting bladder emptying?","volume":"134","author":"Finkbeiner","year":"1985","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2006.12.018_bib7","doi-asserted-by":"crossref","first-page":"305","DOI":"10.1007\/s003450050072","article-title":"The neurophysiology of urinary retention in young women and its treatment by neuromodulation","volume":"16","author":"Goodwin","year":"1998","journal-title":"World J Urol"},{"key":"10.1016\/j.urology.2006.12.018_bib8","doi-asserted-by":"crossref","first-page":"335","DOI":"10.1111\/j.1464-410X.2004.04979.x","article-title":"Long-term results of sacral neuromodulation for women with urinary retention","volume":"94","author":"Dasgupta","year":"2004","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2006.12.018_bib9","doi-asserted-by":"crossref","first-page":"547","DOI":"10.1002\/nau.1930130509","article-title":"Detrusor-myoplasty, innervated rectus muscle transposition study, and functional effect on the spinal cord injury rat model","volume":"13","author":"Chancellor","year":"1994","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2006.12.018_bib10","doi-asserted-by":"crossref","first-page":"215","DOI":"10.1007\/s002400050049","article-title":"The latissimus dorsi bladder myoplasty to assist detrusor function","volume":"26","author":"Von Heyden","year":"1998","journal-title":"Urol Res"},{"key":"10.1016\/j.urology.2006.12.018_bib11","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1016\/S0361-9230(02)00833-X","article-title":"Effect of cryoinjury in the contractile parameters of bladder muscle strips: a model of impaired detrusor contractility","volume":"59","author":"Somogyi","year":"2002","journal-title":"Brain Res Bull"},{"key":"10.1016\/j.urology.2006.12.018_bib12","doi-asserted-by":"crossref","first-page":"1185","DOI":"10.1016\/j.neuint.2004.06.016","article-title":"Loss of caveolin-1 expression is associated with disruption of muscarinic cholinergic activities in the urinary bladder","volume":"45","author":"Lai","year":"2004","journal-title":"Neurochem Int"},{"key":"10.1016\/j.urology.2006.12.018_bib13","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1097\/01.ju.0000105102.72295.b8","article-title":"Urogenital alterations in aged male caveolin-1 knockout mice","volume":"171","author":"Woodman","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2006.12.018_bib14","doi-asserted-by":"crossref","first-page":"1241","DOI":"10.1016\/S0002-9440(10)63920-X","article-title":"Disruption of the caveolin-1 gene impairs renal calcium reabsorption and leads to hypercalciuria and urolithiasis","volume":"162","author":"Cao","year":"2003","journal-title":"Am J Pathol"},{"key":"10.1016\/j.urology.2006.12.018_bib15","doi-asserted-by":"crossref","first-page":"15124","DOI":"10.1021\/bi0356348","article-title":"Caveolin-1 null (\u2212\/\u2212) mice show dramatic reductions in life span","volume":"42","author":"Park","year":"2003","journal-title":"Biochemistry"},{"key":"10.1016\/j.urology.2006.12.018_bib16","doi-asserted-by":"crossref","first-page":"10627","DOI":"10.1523\/JNEUROSCI.22-24-10627.2002","article-title":"Mice lacking M2 and M3 muscarinic acetylcholine receptors are devoid of cholinergic smooth muscle contractions but still viable","volume":"22","author":"Matsui","year":"2002","journal-title":"J Neurosci"},{"key":"10.1016\/j.urology.2006.12.018_bib17","doi-asserted-by":"crossref","first-page":"17","DOI":"10.1016\/j.urology.2003.11.003","article-title":"Management of detrusor dysfunction in the elderly: changes in acetylcholine and adenosine triphosphate release during aging","volume":"63","author":"Yoshida","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2006.12.018_bib18","doi-asserted-by":"crossref","first-page":"38121","DOI":"10.1074\/jbc.M105408200","article-title":"Caveolin-1 null mice are viable but show evidence of hyperproliferative and vascular abnormalities","volume":"276","author":"Razani","year":"2001","journal-title":"J Biol Chem"},{"key":"10.1016\/j.urology.2006.12.018_bib19","doi-asserted-by":"crossref","first-page":"91","DOI":"10.1016\/S0303-7207(01)00472-5","article-title":"Changes in caveolin subtype protein expression in aging rat organs","volume":"176","author":"Kawabe","year":"2001","journal-title":"Mol Cell Endocrinol"},{"key":"10.1016\/j.urology.2006.12.018_bib20","doi-asserted-by":"crossref","first-page":"734","DOI":"10.1016\/S0022-5347(05)66052-1","article-title":"Decreased trabecular smooth muscle and caveolin-1 expression in the penile tissue of aged rats","volume":"166","author":"Bakircioglu","year":"2001","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2006.12.018_bib21","doi-asserted-by":"crossref","first-page":"H2457","DOI":"10.1152\/ajpheart.01090.2004","article-title":"Decline in caveolin-1 expression and scaffolding of G-protein receptor kinase-2 with age in Fischer 344 aortic vascular smooth muscle","volume":"288","author":"Schutzer","year":"2004","journal-title":"Am J Physiol Heart Circ Physiol"},{"key":"10.1016\/j.urology.2006.12.018_bib22","doi-asserted-by":"crossref","first-page":"226","DOI":"10.1002\/jcp.1071","article-title":"Loss of functional caveolae during senescence of human fibroblasts","volume":"187","author":"Wheaton","year":"2001","journal-title":"J Cell Physiol"},{"issue":"5 Pt 2","key":"10.1016\/j.urology.2006.12.018_bib23","doi-asserted-by":"crossref","first-page":"1657","DOI":"10.1016\/S0022-5347(17)35867-6","article-title":"Structural basis of geriatric voiding dysfunction","volume":"150","author":"Elbadawi","year":"1993","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2006.12.018_bib24","first-page":"672","article-title":"Caveolin, a protein component of caveolae membrane coats","volume":"68","author":"Rothberg","year":"1993","journal-title":"Cell"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429506026422?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429506026422?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2021,8,8]],"date-time":"2021-08-08T21:27:24Z","timestamp":1628458044000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429506026422"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2007,2]]},"references-count":24,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2007,2]]}},"alternative-id":["S0090429506026422"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2006.12.018","relation":{"has-review":[{"id-type":"doi","id":"10.3410\/f.726277110.793516656","asserted-by":"object"}]},"ISSN":["0090-4295"],"issn-type":[{"value":"0090-4295","type":"print"}],"subject":[],"published":{"date-parts":[[2007,2]]}}}