{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T13:18:27Z","timestamp":1765545507628},"reference-count":21,"publisher":"Elsevier BV","issue":"3","license":[{"start":{"date-parts":[[2008,3,1]],"date-time":"2008-03-01T00:00:00Z","timestamp":1204329600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Urology"],"published-print":{"date-parts":[[2008,3]]},"DOI":"10.1016\/j.urology.2007.11.010","type":"journal-article","created":{"date-parts":[[2008,3,14]],"date-time":"2008-03-14T13:55:49Z","timestamp":1205502949000},"page":"541-545","source":"Crossref","is-referenced-by-count":8,"title":["Effect of Age on the Role of Rho-Kinase in Short-term Partial Bladder Outlet Obstruction"],"prefix":"10.1016","volume":"71","author":[{"given":"Ahmet","family":"Guven","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei-Yu","family":"Lin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul","family":"Neuman","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barry A.","family":"Kogan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert","family":"Levin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anita","family":"Mannikarottu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2007.11.010_bib1","first-page":"535","article-title":"Benign Prostatic Hyperplasia","author":"Chatelain","year":"2001"},{"key":"10.1016\/j.urology.2007.11.010_bib2","doi-asserted-by":"crossref","first-page":"609","DOI":"10.1002\/1520-6777(2000)19:5<609::AID-NAU7>3.0.CO;2-H","article-title":"Obstructive response of human bladder to BPH vs. rabbit bladder response to partial outlet obstruction: a direct comparison","volume":"19","author":"Levin","year":"2000","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2007.11.010_bib3","doi-asserted-by":"crossref","first-page":"935","DOI":"10.1152\/physrev.00038.2003","article-title":"Urinary bladder contraction and relaxation: physiology and pathophysiology","volume":"84","author":"Andersson","year":"2004","journal-title":"Physiol Rev"},{"key":"10.1016\/j.urology.2007.11.010_bib4","doi-asserted-by":"crossref","first-page":"14","DOI":"10.1016\/S1569-9056(02)00119-7","article-title":"Obstructive bladder dysfunction: morphological, biochemical, and molecular changes","volume":"1","author":"Levin","year":"2002","journal-title":"Eur Urol Suppl"},{"issue":"7","key":"10.1016\/j.urology.2007.11.010_bib5","doi-asserted-by":"crossref","first-page":"1036","DOI":"10.1002\/nau.20433","article-title":"Novel biomarkers of bladder decompensation after partial bladder obstruction","volume":"26","author":"Guven","year":"2007","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2007.11.010_bib6","doi-asserted-by":"crossref","first-page":"177","DOI":"10.1111\/j.1469-7793.2000.t01-2-00177.x","article-title":"Signal transduction by G-proteins, rho-kinase and protein phosphatase to smooth muscle and non-muscle myosin II","volume":"522","author":"Somlyo","year":"2000","journal-title":"J Physiol"},{"key":"10.1016\/j.urology.2007.11.010_bib7","doi-asserted-by":"crossref","first-page":"748","DOI":"10.1097\/01.ju.0000130419.32165.6b","article-title":"Ca2+ sensitization in contraction of human bladder smooth muscle","volume":"172","author":"Takahashi","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2007.11.010_bib8","doi-asserted-by":"crossref","first-page":"967","DOI":"10.1152\/physrev.1996.76.4.967","article-title":"Mechanisms of smooth muscle contraction","volume":"76","author":"Horowitz","year":"1996","journal-title":"Physiol Rev"},{"key":"10.1016\/j.urology.2007.11.010_bib9","doi-asserted-by":"crossref","first-page":"20246","DOI":"10.1074\/jbc.271.34.20246","article-title":"Phosphorylation and activation of myosin by Rho-associated kinase (Rho-kinase)","volume":"271","author":"Amano","year":"1996","journal-title":"J Biol Chem"},{"key":"10.1016\/j.urology.2007.11.010_bib10","doi-asserted-by":"crossref","first-page":"37385","DOI":"10.1074\/jbc.274.52.37385","article-title":"Inhibitory phosphorylation site for Rho-associated kinase on smooth muscle myosin phosphatase","volume":"274","author":"Feng","year":"1999","journal-title":"J Biol Chem"},{"key":"10.1016\/j.urology.2007.11.010_bib11","doi-asserted-by":"crossref","first-page":"F990","DOI":"10.1152\/ajprenal.00378.2002","article-title":"Obstruction-induced changes in urinary bladder smooth muscle contractility: a role for Rho kinase","volume":"285","author":"Bing","year":"2003","journal-title":"Am J Physiol Renal Physiol"},{"key":"10.1016\/j.urology.2007.11.010_bib12","doi-asserted-by":"crossref","first-page":"757","DOI":"10.1038\/sj.bjp.0705109","article-title":"Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle","volume":"138","author":"Wibberley","year":"2003","journal-title":"Br J Pharmacol"},{"issue":"7","key":"10.1016\/j.urology.2007.11.010_bib13","doi-asserted-by":"crossref","first-page":"1043","DOI":"10.1002\/nau.20435","article-title":"Long term partial bladder outlet obstruction induced contractile dysfunction in male rabbits: a role for Rho-kinase","volume":"26","author":"Guven","year":"2007","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2007.11.010_bib14","doi-asserted-by":"crossref","first-page":"302","DOI":"10.1097\/01.ju.0000142100.06466.49","article-title":"Regional alterations in the expression of smooth muscle myosin isoforms in response to partial bladder outlet obstruction","volume":"173","author":"Mannikarottu","year":"2005","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2007.11.010_bib15","doi-asserted-by":"crossref","first-page":"389","DOI":"10.1016\/0092-8674(92)90163-7","article-title":"The small GTP-binding protein rho regulates the assembly of focal adhesions and actin stress fibers in response to growth factors","volume":"70","author":"Ridley","year":"1992","journal-title":"Cell"},{"key":"10.1016\/j.urology.2007.11.010_bib16","doi-asserted-by":"crossref","first-page":"458","DOI":"10.1161\/01.RES.84.4.458","article-title":"Rho family small G proteins play critical roles in mechanical stress-induced hypertrophic responses in cardiac myocytes","volume":"84","author":"Aikawa","year":"1999","journal-title":"Circ Res"},{"key":"10.1016\/j.urology.2007.11.010_bib17","doi-asserted-by":"crossref","first-page":"990","DOI":"10.1038\/40187","article-title":"Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension","volume":"389","author":"Uehata","year":"1997","journal-title":"Nature"},{"key":"10.1016\/j.urology.2007.11.010_bib18","doi-asserted-by":"crossref","first-page":"295","DOI":"10.1002\/nau.20122","article-title":"Rho-kinase inhibition suppresses bladder hyperactivity in spontaneously hypertensive rats","volume":"24","author":"Rajasekaran","year":"2005","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2007.11.010_bib19","doi-asserted-by":"crossref","first-page":"L624","DOI":"10.1152\/ajplung.00215.2004","article-title":"The tone of pulmonary smooth muscle: ROK and Rho music?","volume":"287","author":"Sylvester","year":"2004","journal-title":"Am J Physiol Lung Cell Mol Physiol"},{"key":"10.1016\/j.urology.2007.11.010_bib20","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1097\/00005392-200101000-00072","article-title":"The effect of bladder outflow obstruction on detrusor blood flow changes during the voiding cycle in conscious pigs","volume":"165","author":"Greenland","year":"2001","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2007.11.010_bib21","doi-asserted-by":"crossref","first-page":"2251","DOI":"10.1161\/01.STR.0000181077.84981.11","article-title":"Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection","volume":"36","author":"Rikitake","year":"2005","journal-title":"Stroke"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429507023801?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429507023801?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2019,5,9]],"date-time":"2019-05-09T03:55:25Z","timestamp":1557374125000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429507023801"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,3]]},"references-count":21,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2008,3]]}},"alternative-id":["S0090429507023801"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2007.11.010","relation":{},"ISSN":["0090-4295"],"issn-type":[{"value":"0090-4295","type":"print"}],"subject":[],"published":{"date-parts":[[2008,3]]}}}