{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,12,18]],"date-time":"2025-12-18T08:56:48Z","timestamp":1766048208072,"version":"3.44.0"},"reference-count":30,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2010,8,1]],"date-time":"2010-08-01T00:00:00Z","timestamp":1280620800000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","goldjournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology"],"published-print":{"date-parts":[[2010,8]]},"DOI":"10.1016\/j.urology.2010.03.040","type":"journal-article","created":{"date-parts":[[2010,5,27]],"date-time":"2010-05-27T09:03:11Z","timestamp":1274950991000},"page":"508.e1-508.e5","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":11,"title":["Renal Tissue Damage After Experimental Pyelonephritis: Role of Antioxidants and Selective Cyclooxygenase-2 Inhibitors"],"prefix":"10.1016","volume":"76","author":[{"given":"Serhat","family":"Gurocak","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iyimser","family":"Ure","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Cumaoglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ipek Isik","family":"Gonul","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ilker","family":"Sen","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ozgur","family":"Tan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aysel","family":"Aricioglu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ibrahim","family":"Bozkirli","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2010.03.040_bib1","doi-asserted-by":"crossref","first-page":"1327","DOI":"10.1016\/S0022-5347(17)37555-9","article-title":"Renal scarring following reflux and nonreflux pyelonephritis in children: evaluation with 99mtechnetium-dimercaptosuccinic acid scintigraphy","volume":"147","author":"Rushton","year":"1992","journal-title":"J Urol"},{"issue":"Suppl 1","key":"10.1016\/j.urology.2010.03.040_bib2","doi-asserted-by":"crossref","first-page":"S76","DOI":"10.1007\/s00247-007-0587-x","article-title":"Pyelonephritis, renal scarring, and reflux nephropathy: a pediatric urologist's perspective","volume":"38","author":"Smith","year":"2008","journal-title":"Pediatr Radiol"},{"key":"10.1016\/j.urology.2010.03.040_bib3","doi-asserted-by":"crossref","first-page":"4168","DOI":"10.1128\/iai.59.11.4168-4172.1991","article-title":"Extra cellular release of ROS fromhuman neutrophils upon interaction with E. coli strain causing renal scarring","volume":"59","author":"Mundi","year":"1991","journal-title":"Infect Immun"},{"key":"10.1016\/j.urology.2010.03.040_bib4","doi-asserted-by":"crossref","first-page":"1681","DOI":"10.1016\/S0022-5347(05)69004-0","article-title":"Suppression of renal inflammation with vitamins A and E in ascending pyelonephritis in rats","volume":"161","author":"Bennett","year":"1991","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2010.03.040_bib5","doi-asserted-by":"crossref","first-page":"1055","DOI":"10.1046\/j.1464-410x.1999.00063.x","article-title":"The role of vitamin A in preventing renal scarring secondary to pyelonephritis","volume":"83","author":"Kavuk\u00e7u","year":"1999","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2010.03.040_bib6","doi-asserted-by":"crossref","first-page":"225","DOI":"10.1016\/S0147-9571(03)00011-0","article-title":"Prevention of tissue injury in an ascending mouse model of chronic pyelonephritis\u2014role of free radical scavengers","volume":"27","author":"Gupta","year":"2004","journal-title":"Comp Immunol Microbiol Infect Dis"},{"key":"10.1016\/j.urology.2010.03.040_bib7","doi-asserted-by":"crossref","first-page":"1396","DOI":"10.1016\/S0022-5347(05)68319-X","article-title":"Ibuprofen combined with antibiotics suppresses renal scarring due to ascending pyelonephritis in rats","volume":"162","author":"Huang","year":"1999","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2010.03.040_bib8","doi-asserted-by":"crossref","first-page":"451","DOI":"10.1159\/000095088","article-title":"Effect of a selective cyclooxygenase 2 inhibitor on renal scarring","volume":"38","author":"Kucuk","year":"2006","journal-title":"Eur Surg Res"},{"key":"10.1016\/j.urology.2010.03.040_bib9","doi-asserted-by":"crossref","first-page":"790","DOI":"10.1096\/fj.03-0645rev","article-title":"Cyclooxygenases: new forms, new inhibitors, and lessons from the clinic","volume":"18","author":"Warner","year":"2004","journal-title":"FASEB J"},{"key":"10.1016\/j.urology.2010.03.040_bib10","doi-asserted-by":"crossref","first-page":"1726","DOI":"10.1016\/0002-8703(92)90850-U","article-title":"Carnitine and its acyl esters as secondary antioxidants?","volume":"123","author":"Arduini","year":"1992","journal-title":"Am Heart J"},{"key":"10.1016\/j.urology.2010.03.040_bib11","series-title":"Methods in Enzymology","doi-asserted-by":"crossref","first-page":"125","DOI":"10.1016\/S0076-6879(84)05016-3","article-title":"Catalase","author":"Aebi","year":"1984"},{"key":"10.1016\/j.urology.2010.03.040_bib12","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/clinchem\/34.3.497","article-title":"A simple method for clinical assay of superoxide dismutase","volume":"34","author":"Sun","year":"1988","journal-title":"Clin Chem"},{"key":"10.1016\/j.urology.2010.03.040_bib13","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1006\/abio.1996.0292","article-title":"The ferric reducing ability of plasma (FRAP) as a measure of \u201cantioxidant power\u201d: the FRAP Assay","volume":"239","author":"Benzie","year":"1996","journal-title":"Anal Biochem"},{"issue":"1","key":"10.1016\/j.urology.2010.03.040_bib14","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1016\/0003-2697(68)90092-4","article-title":"Estimation of total, protein-bound, and nonprotein sulfhydryl groups in tissue with Ellman's reagent","volume":"25","author":"Sedlak","year":"1968","journal-title":"Anal Biochem"},{"key":"10.1016\/j.urology.2010.03.040_bib15","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0003-2697(02)00606-1","article-title":"Measurement of protein and lipid hydroperoxides in biological systems by the ferric-xylenol orange method","volume":"315","author":"Gay","year":"2003","journal-title":"Anal Biochem"},{"key":"10.1016\/j.urology.2010.03.040_bib16","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1111\/j.1574-695X.1996.tb00213.x","article-title":"Oxygen-dependent and independent mechanisms of renal injury in experimental ascending pyelonephritis","volume":"13","author":"Gupta","year":"1996","journal-title":"FEMS Immunol Med Microbiol"},{"key":"10.1016\/j.urology.2010.03.040_bib17","doi-asserted-by":"crossref","first-page":"316","DOI":"10.1016\/j.numecd.2005.05.003","article-title":"A review of recent studies on malondialdehyde as toxic molecule and biological marker of oxidative stress","volume":"15","author":"Del Rio","year":"2005","journal-title":"Nutr Metab Cardiovasc Dis"},{"key":"10.1016\/j.urology.2010.03.040_bib18","doi-asserted-by":"crossref","first-page":"220","DOI":"10.1111\/j.1600-079X.2006.00357.x","article-title":"Melatonin prevents neutrophil-mediated oxidative injury in Escherichia coli-induced pyelonephritis in rats","volume":"41","author":"Sener","year":"2006","journal-title":"J Pineal Res"},{"key":"10.1016\/j.urology.2010.03.040_bib19","doi-asserted-by":"crossref","first-page":"131","DOI":"10.1007\/s11010-006-9337-x","article-title":"Caffeic acid phenethyl ester suppresses oxidative stress in Escherichia coli-induced pyelonephritis in rats","volume":"297","author":"Celik","year":"2007","journal-title":"Mol Cell Biochem"},{"key":"10.1016\/j.urology.2010.03.040_bib20","doi-asserted-by":"crossref","first-page":"2249","DOI":"10.1016\/j.peptides.2006.03.029","article-title":"Oxytocin alleviates oxidative renal injury in pyelonephritic rats via a neutrophil-dependent mechanism","volume":"27","author":"Biyikli","year":"2006","journal-title":"Peptides"},{"key":"10.1016\/j.urology.2010.03.040_bib21","doi-asserted-by":"crossref","first-page":"677","DOI":"10.1111\/j.1471-4159.2007.05174.x","article-title":"Excitotoxic damage, disrupted energy metabolism, and oxidative stress in the rat brain: antioxidant and neuroprotective effects of L-carnitine","volume":"105","author":"Silva-Adaya","year":"2008","journal-title":"J Neurochem"},{"key":"10.1016\/j.urology.2010.03.040_bib22","doi-asserted-by":"crossref","first-page":"172","DOI":"10.1080\/07315724.2005.10719462","article-title":"Decreasing oxidative stress with choline and carnitine in women","volume":"24","author":"Sachan","year":"2005","journal-title":"J Am Coll Nutr"},{"key":"10.1016\/j.urology.2010.03.040_bib23","doi-asserted-by":"crossref","first-page":"629","DOI":"10.1042\/bj3380629","article-title":"Crosslinking of DNA and proteins induced by protein hydroperoxides","volume":"338","author":"Gebicki","year":"1999","journal-title":"Biochem J"},{"key":"10.1016\/j.urology.2010.03.040_bib24","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1016\/j.ejphar.2004.06.017","article-title":"In vitro comparative assessment of the scavenging activity against three reactive oxygen species of non-steroidal anti-inflammatory drugs from the oxicam and sulfoanilide families","volume":"496","author":"Van Antwerpen","year":"2004","journal-title":"Eur J Pharmacol"},{"key":"10.1016\/j.urology.2010.03.040_bib25","doi-asserted-by":"crossref","first-page":"169","DOI":"10.1081\/DCT-120022645","article-title":"In vivo effects of meloxicam, celecoxib, and ibuprofen on free radical metabolism in human erythrocytes","volume":"26","author":"Cimen","year":"2003","journal-title":"Drug Chem Toxicol"},{"key":"10.1016\/j.urology.2010.03.040_bib26","doi-asserted-by":"crossref","first-page":"519","DOI":"10.1515\/bchm2.1983.364.1.519","article-title":"Formation of singlet oxygen detected by low-level chemiluminescence during enzymatic reduction of prostaglandin G2 to H2","volume":"364","author":"Cadenas","year":"1983","journal-title":"Hoppe-Seylers Z Physiol Chem"},{"key":"10.1016\/j.urology.2010.03.040_bib27","doi-asserted-by":"crossref","first-page":"163","DOI":"10.1016\/j.etp.2006.06.004","article-title":"Effects of cyclooxygenase inhibition on the gastrointestinal tract","volume":"58","author":"Radi","year":"2006","journal-title":"Exp Toxicol Pathol"},{"issue":"2","key":"10.1016\/j.urology.2010.03.040_bib28","doi-asserted-by":"crossref","first-page":"61","DOI":"10.1191\/0960327102ht210oa","article-title":"Oxidants and antioxidative defense","volume":"21","author":"Grune","year":"2002","journal-title":"Hum Exp Toxicol"},{"key":"10.1016\/j.urology.2010.03.040_bib29","doi-asserted-by":"crossref","first-page":"1503","DOI":"10.1007\/s00467-008-0853-7","article-title":"Vitamin E administration at the onset of fever prevents renal scarring in acute pyelonephritis","volume":"23","author":"Sadeghi","year":"2008","journal-title":"Pediatr Nephrol"},{"key":"10.1016\/j.urology.2010.03.040_bib30","doi-asserted-by":"crossref","first-page":"890","DOI":"10.1172\/JCI1112","article-title":"Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine\/paracrine mechanisms involving TGF-beta, PGE2, and PAF","volume":"101","author":"Fadok","year":"1998","journal-title":"J Clin Invest"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429510004061?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429510004061?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T01:53:39Z","timestamp":1758765219000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429510004061"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2010,8]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2010,8]]}},"alternative-id":["S0090429510004061"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2010.03.040","relation":{},"ISSN":["0090-4295"],"issn-type":[{"type":"print","value":"0090-4295"}],"subject":[],"published":{"date-parts":[[2010,8]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Renal Tissue Damage After Experimental Pyelonephritis: Role of Antioxidants and Selective Cyclooxygenase-2 Inhibitors","name":"articletitle","label":"Article Title"},{"value":"Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urology.2010.03.040","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2010 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}