{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T13:38:30Z","timestamp":1762004310529,"version":"3.44.0"},"reference-count":16,"publisher":"Elsevier BV","issue":"6","license":[{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2011,6,1]],"date-time":"2011-06-01T00:00:00Z","timestamp":1306886400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","goldjournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology"],"published-print":{"date-parts":[[2011,6]]},"DOI":"10.1016\/j.urology.2011.02.017","type":"journal-article","created":{"date-parts":[[2011,6,10]],"date-time":"2011-06-10T06:07:34Z","timestamp":1307686054000},"page":"1507.e15-1507.e20","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":13,"title":["Effect of the Phytotherapeutic Agent Eviprostat on Inflammatory Changes and Cytokine Production in a Rat Model of Nonbacterial Prostatitis"],"prefix":"10.1016","volume":"77","author":[{"given":"Hiroyuki","family":"Tsunemori","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mikio","family":"Sugimoto","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhang","family":"Xia","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rikiya","family":"Taoka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michiko","family":"Oka","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiyuki","family":"Kakehi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2011.02.017_bib1","first-page":"S122","article-title":"BPH: epidemiology and comorbidities","volume":"12","author":"McVary","year":"2006","journal-title":"Am J Manag Care"},{"key":"10.1016\/j.urology.2011.02.017_bib2","first-page":"1","article-title":"Prostatic inflammation in benign prostatic hyperplasia\u2014the third component?","volume":"1","author":"Nickel","year":"1994","journal-title":"Can J Urol"},{"key":"10.1016\/j.urology.2011.02.017_bib3","doi-asserted-by":"crossref","first-page":"2387","DOI":"10.1056\/NEJMoa030656","article-title":"The long-term effect of doxazosin, finasteride, and combination therapy on the clinical progression of benign prostatic hyperplasia","volume":"349","author":"McConnell","year":"2003","journal-title":"N Engl J Med"},{"key":"10.1016\/j.urology.2011.02.017_bib4","doi-asserted-by":"crossref","first-page":"7598","DOI":"10.1073\/pnas.112191399","article-title":"Symptomatic and asymptomatic benign prostatic hyperplasia: molecular differentiation by using microarrays","volume":"99","author":"Prakash","year":"2002","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.urology.2011.02.017_bib5","doi-asserted-by":"crossref","first-page":"11514","DOI":"10.1073\/pnas.94.21.11514","article-title":"MIC-1, a novel macrophage inhibitory cytokine, is a divergent member of the TGF-beta superfamily","volume":"94","author":"Bootcov","year":"1997","journal-title":"Proc Natl Acad Sci U S A"},{"key":"10.1016\/j.urology.2011.02.017_bib6","doi-asserted-by":"crossref","first-page":"2330","DOI":"10.1097\/01.ju.0000127760.87421.e9","article-title":"Association of prostatic inflammation with down-regulation of macrophage inhibitory cytokine-1 gene in symptomatic benign prostatic hyperplasia","volume":"171","author":"Taoka","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2011.02.017_bib7","doi-asserted-by":"crossref","first-page":"122","DOI":"10.1002\/pros.1126","article-title":"Effect of cernitin pollen-extract on experimental nonbacterial prostatitis in rats","volume":"49","author":"Kamijo","year":"2001","journal-title":"Prostate"},{"key":"10.1016\/j.urology.2011.02.017_bib8","doi-asserted-by":"crossref","first-page":"410","DOI":"10.1016\/j.urology.2008.07.034","article-title":"Influence of inflammation and aging on macrophage inhibitory cytokine-1 gene expression in rat ventral prostate","volume":"73","author":"Taniguchi","year":"2009","journal-title":"Urology"},{"key":"10.1016\/j.urology.2011.02.017_bib9","doi-asserted-by":"crossref","first-page":"1404","DOI":"10.1002\/pros.20985","article-title":"Effect of the phytotherapeutic agent eviprostat on 17beta-estradiol-induced nonbacterial inflammation in the rat prostate","volume":"69","author":"Oka","year":"2009","journal-title":"Prostate"},{"key":"10.1016\/j.urology.2011.02.017_bib10","doi-asserted-by":"crossref","first-page":"465","DOI":"10.1016\/j.phymed.2007.04.006","article-title":"Relevance of anti-reactive oxygen species activity to anti-inflammatory activity of components of eviprostat, a phytotherapeutic agent for benign prostatic hyperplasia","volume":"14","author":"Oka","year":"2007","journal-title":"Phytomedicine"},{"key":"10.1016\/j.urology.2011.02.017_bib11","doi-asserted-by":"crossref","first-page":"340","DOI":"10.1016\/j.urology.2009.02.064","article-title":"Evaluation of interleukin-8 in expressed prostatic secretion as a reliable biomarker of inflammation in benign prostatic hyperplasia","volume":"74","author":"Liu","year":"2009","journal-title":"Urology"},{"key":"10.1016\/j.urology.2011.02.017_bib12","doi-asserted-by":"crossref","first-page":"185","DOI":"10.1016\/j.cyto.2009.06.004","article-title":"Eviprostat suppresses proinflammatory gene expression in the prostate of rats with partial bladder-outlet obstruction: a genome-wide DNA microarray analysis","volume":"47","author":"Tagaya","year":"2009","journal-title":"Cytokines"},{"key":"10.1016\/j.urology.2011.02.017_bib13","doi-asserted-by":"crossref","first-page":"1025","DOI":"10.1016\/S0090-4295(00)00844-X","article-title":"Evaluation of the cytokines interleukin 8 and epithelial neutrophil activating peptide 78 as indicators of inflammation in prostatic secretions","volume":"56","author":"Hochreiter","year":"2000","journal-title":"Urology"},{"key":"10.1016\/j.urology.2011.02.017_bib14","doi-asserted-by":"crossref","first-page":"524","DOI":"10.1016\/j.eururo.2006.07.016","article-title":"Seminal plasma cytokines and chemokines in prostate inflammation: interleukin 8 as a predictive biomarker in chronic prostatitis\/chronic pelvic pain syndrome and benign prostatic hyperplasia","volume":"51","author":"Penna","year":"2007","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2011.02.017_bib15","doi-asserted-by":"crossref","first-page":"1202","DOI":"10.1016\/j.eururo.2006.12.011","article-title":"Is benign prostatic hyperplasia (BPH) an immune inflammatory disease?","volume":"51","author":"Kramer","year":"2007","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2011.02.017_bib16","doi-asserted-by":"crossref","first-page":"544","DOI":"10.1016\/j.eururo.2009.05.046","article-title":"A pollen extract (cernilton) in patients with inflammatory chronic prostatitis-chronic pelvic pain syndrome: a multicentre, randomised, prospective, double-blind, placebo-controlled phase 3 study","volume":"56","author":"Wagenlehner","year":"2009","journal-title":"Eur Urol"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429511001786?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429511001786?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T01:54:27Z","timestamp":1758765267000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429511001786"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2011,6]]},"references-count":16,"journal-issue":{"issue":"6","published-print":{"date-parts":[[2011,6]]}},"alternative-id":["S0090429511001786"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2011.02.017","relation":{},"ISSN":["0090-4295"],"issn-type":[{"type":"print","value":"0090-4295"}],"subject":[],"published":{"date-parts":[[2011,6]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Effect of the Phytotherapeutic Agent Eviprostat on Inflammatory Changes and Cytokine Production in a Rat Model of Nonbacterial Prostatitis","name":"articletitle","label":"Article Title"},{"value":"Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urology.2011.02.017","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2011 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}