{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,9,26]],"date-time":"2025-09-26T00:02:57Z","timestamp":1758844977013,"version":"3.44.0"},"reference-count":29,"publisher":"Elsevier BV","issue":"2","license":[{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,2,1]],"date-time":"2012-02-01T00:00:00Z","timestamp":1328054400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","goldjournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology"],"published-print":{"date-parts":[[2012,2]]},"DOI":"10.1016\/j.urology.2011.10.010","type":"journal-article","created":{"date-parts":[[2011,12,7]],"date-time":"2011-12-07T21:01:05Z","timestamp":1323291665000},"page":"483.e13-483.e17","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":36,"title":["Intravesical Chondroitin Sulfate Inhibits Recruitment of Inflammatory Cells in an Acute Acid Damage \u201cLeaky Bladder\u201d Model of Cystitis"],"prefix":"10.1016","volume":"79","author":[{"given":"Christopher D.","family":"Engles","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paul J.","family":"Hauser","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shivon N.","family":"Abdullah","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daniel J.","family":"Culkin","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert E.","family":"Hurst","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"issue":"4 suppl","key":"10.1016\/j.urology.2011.10.010_bib1","doi-asserted-by":"crossref","first-page":"64","DOI":"10.1016\/j.urology.2006.05.048","article-title":"Current diagnosis of interstitial cystitis: an evolving paradigm","volume":"69","author":"Evans","year":"2007","journal-title":"Urology"},{"key":"10.1016\/j.urology.2011.10.010_bib2","doi-asserted-by":"crossref","first-page":"353","DOI":"10.1097\/MOU.0b013e3282fcea88","article-title":"What is new in bladder pain syndrome\/interstitial cystitis?","volume":"18","author":"Hanno","year":"2008","journal-title":"Curr Opin Urol"},{"issue":"4 Pt. 1","key":"10.1016\/j.urology.2011.10.010_bib3","doi-asserted-by":"crossref","first-page":"1242","DOI":"10.1097\/01.ju.0000137953.49304.6c","article-title":"Comorbidity of interstitial cystitis with other unexplained clinical conditions","volume":"172","author":"Buffington","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2011.10.010_bib4","doi-asserted-by":"crossref","first-page":"467","DOI":"10.1016\/S0025-7125(03)00151-2","article-title":"Interstitial cystitis: a chronic pelvic pain syndrome","volume":"88","author":"Nickel","year":"2004","journal-title":"Med Clin North Am"},{"issue":"4 suppl","key":"10.1016\/j.urology.2011.10.010_bib5","doi-asserted-by":"crossref","first-page":"53","DOI":"10.1016\/j.urology.2006.05.049","article-title":"The emerging presence of interstitial cystitis in gynecologic patients with chronic pelvic pain","volume":"69","author":"Stanford","year":"2007","journal-title":"Urology"},{"key":"10.1016\/j.urology.2011.10.010_bib6","doi-asserted-by":"crossref","first-page":"F1461","DOI":"10.1152\/ajprenal.00311.2007","article-title":"Changes in urinary bladder smooth muscle function in response to colonic inflammation","volume":"293","author":"Noronha","year":"2007","journal-title":"Am J Physiol Ren Physiol"},{"key":"10.1016\/j.urology.2011.10.010_bib7","doi-asserted-by":"crossref","first-page":"936","DOI":"10.1111\/j.1365-2982.2006.00807.x","article-title":"Hyperexcitability of convergent colon and bladder dorsal root ganglion neurons after colonic inflammation: mechanism for pelvic organ cross-talk","volume":"18","author":"Malykhina","year":"2006","journal-title":"Neurogastroenterol Motil"},{"key":"10.1016\/j.urology.2011.10.010_bib8","doi-asserted-by":"crossref","first-page":"440","DOI":"10.1007\/s11934-006-0051-8","article-title":"Dysfunction of bladder urothelium and bladder urothelial cells in interstitial cystitis","volume":"7","author":"Graham","year":"2006","journal-title":"Curr Urol Rep"},{"issue":"4 suppl","key":"10.1016\/j.urology.2011.10.010_bib9","doi-asserted-by":"crossref","first-page":"9","DOI":"10.1016\/j.urology.2006.03.084","article-title":"The role of the urinary epithelium in the pathogenesis of interstitial cystitis\/prostatitis\/urethritis","volume":"69","author":"Parsons","year":"2007","journal-title":"Urology"},{"key":"10.1016\/j.urology.2011.10.010_bib10","doi-asserted-by":"crossref","first-page":"23","DOI":"10.1098\/rstb.1974.0013","article-title":"The ultrastructure and chemistry of the luminal plasma membrane of the mammalian urinary bladder: a structure with low permeability to water and ions","volume":"268","author":"Hicks","year":"1974","journal-title":"Philos Trans R Soc Lond B Biol Sci"},{"key":"10.1016\/j.urology.2011.10.010_bib11","doi-asserted-by":"crossref","first-page":"419","DOI":"10.1016\/S0022-5347(05)67375-2","article-title":"A new direct test of bladder permeability","volume":"164","author":"Erickson","year":"2000","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2011.10.010_bib12","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/j.juro.2007.09.022","article-title":"Abnormal expression of differentiation related proteins and proteoglycan core proteins in the urothelium of patients with interstitial cystitis","volume":"179","author":"Hauser","year":"2008","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2011.10.010_bib13","doi-asserted-by":"crossref","first-page":"142","DOI":"10.1016\/j.juro.2006.08.096","article-title":"Discovery of morphological subgroups that correlate with severity of symptoms in interstitial cystitis: a proposed biopsy classification system","volume":"177","author":"Leiby","year":"2007","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2011.10.010_bib14","doi-asserted-by":"crossref","first-page":"1554","DOI":"10.1097\/01.ju.0000118938.09119.a5","article-title":"Abnormal expression of molecular markers for bladder impermeability and differentiation in urothelium of interstitial cystitis patients","volume":"171","author":"Slobodov","year":"2004","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2011.10.010_bib15","doi-asserted-by":"crossref","first-page":"409","DOI":"10.1111\/j.1442-2042.2006.01301.x","article-title":"Toxic factors in human urine that injure urothelium","volume":"13","author":"Rajasekaran","year":"2006","journal-title":"Int J Urol"},{"key":"10.1016\/j.urology.2011.10.010_bib16","doi-asserted-by":"crossref","first-page":"280","DOI":"10.1054\/tice.2001.0175","article-title":"Succession of events in desquamation of superficial urothelial cells as a response to stress induced by prolonged constant illumination","volume":"33","author":"Veranic","year":"2001","journal-title":"Tissue Cell"},{"key":"10.1016\/j.urology.2011.10.010_bib17","doi-asserted-by":"crossref","first-page":"515","DOI":"10.1002\/nau.1930130503","article-title":"Abnormal sensitivity to intravesical potassium in interstitial cystitis and radiation cystitis","volume":"13","author":"Parsons","year":"1994","journal-title":"Neurourol Urodyn"},{"key":"10.1016\/j.urology.2011.10.010_bib18","doi-asserted-by":"crossref","first-page":"346","DOI":"10.1016\/S0022-5347(17)34945-5","article-title":"Bladder permeability in interstitial cystitis is similar to that of normal volunteers: direct measurement by transvesical absorption of 99mtechnetium-diethylenetriaminepentaacetic acid","volume":"151","author":"Chelsky","year":"1994","journal-title":"J Urol"},{"issue":"3 Pt. 1","key":"10.1016\/j.urology.2011.10.010_bib19","doi-asserted-by":"crossref","first-page":"786","DOI":"10.1016\/S0022-5347(01)64316-7","article-title":"Excretion of fluorescein in the urine of women with interstitial cystitis","volume":"158","author":"Buffington","year":"1997","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2011.10.010_bib20","doi-asserted-by":"crossref","first-page":"56","DOI":"10.1111\/j.1464-410X.2008.08028.x","article-title":"A real-life multicentre clinical practice study to evaluate the efficacy and safety of intravesical chondroitin sulphate for the treatment of interstitial cystitis","volume":"103","author":"Nickel","year":"2009","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2011.10.010_bib21","doi-asserted-by":"crossref","first-page":"287","DOI":"10.1517\/14656566.5.2.287","article-title":"Current strategies for managing interstitial cystitis","volume":"5","author":"Parsons","year":"2004","journal-title":"Expert Opin Pharmacother"},{"key":"10.1016\/j.urology.2011.10.010_bib22","doi-asserted-by":"crossref","first-page":"2477","DOI":"10.1016\/j.juro.2009.07.013","article-title":"Restoration of the barrier function to acid-damaged bladder by intravesical chondroitin sulfate","volume":"182","author":"Hauser","year":"2009","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2011.10.010_bib23","doi-asserted-by":"crossref","first-page":"2033","DOI":"10.1023\/A:1010668005729","article-title":"Coagulation protein function: enhancement of the anticoagulant effect of acetaldehyde by sulfated glycosaminoglycans","volume":"46","author":"Brecher","year":"2001","journal-title":"Dig Dis Sci"},{"key":"10.1016\/j.urology.2011.10.010_bib24","doi-asserted-by":"crossref","first-page":"12959","DOI":"10.1021\/bi990711d","article-title":"Glycosaminoglycans interact selectively with chemokines and modulate receptor binding and cellular responses","volume":"38","author":"Kuschert","year":"1999","journal-title":"Biochemistry"},{"key":"10.1016\/j.urology.2011.10.010_bib25","doi-asserted-by":"crossref","first-page":"317","DOI":"10.1078\/0171-9335-00392","article-title":"Hyaluronan catabolism: a new metabolic pathway","volume":"83","author":"Stern","year":"2004","journal-title":"Eur J Cell Biol"},{"key":"10.1016\/j.urology.2011.10.010_bib26","doi-asserted-by":"crossref","first-page":"83","DOI":"10.4293\/108680810X12674612014743","article-title":"The overlap of interstitial cystitis\/painful bladder syndrome and overactive bladder","volume":"14","author":"Chung","year":"2010","journal-title":"JSLS"},{"key":"10.1016\/j.urology.2011.10.010_bib27","doi-asserted-by":"crossref","first-page":"1527","DOI":"10.1016\/j.juro.2008.06.006","article-title":"Urine is necessary to provoke bladder inflammation in protamine sulfate induced urothelial injury","volume":"180","author":"Soler","year":"2008","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2011.10.010_bib28","doi-asserted-by":"crossref","first-page":"923","DOI":"10.1159\/000331969","article-title":"Cytologic examination of urine from patients with interstitial cystitis","volume":"42","author":"Dodd","year":"1998","journal-title":"Acta Cytol"},{"issue":"suppl 1","key":"10.1016\/j.urology.2011.10.010_bib29","doi-asserted-by":"crossref","first-page":"47","DOI":"10.1016\/S0090-4295(01)01129-3","article-title":"Mast cell involvement in interstitial cystitis: a review of human and experimental evidence","volume":"57","author":"Theoharides","year":"2001","journal-title":"Urology"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429511024836?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429511024836?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T01:56:21Z","timestamp":1758765381000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429511024836"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,2]]},"references-count":29,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2012,2]]}},"alternative-id":["S0090429511024836"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2011.10.010","relation":{},"ISSN":["0090-4295"],"issn-type":[{"type":"print","value":"0090-4295"}],"subject":[],"published":{"date-parts":[[2012,2]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Intravesical Chondroitin Sulfate Inhibits Recruitment of Inflammatory Cells in an Acute Acid Damage \u201cLeaky Bladder\u201d Model of Cystitis","name":"articletitle","label":"Article Title"},{"value":"Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urology.2011.10.010","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}