{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T17:01:56Z","timestamp":1791306116619,"version":"4.3.1"},"reference-count":30,"publisher":"Elsevier BV","issue":"5","license":[{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,5,1]],"date-time":"2012-05-01T00:00:00Z","timestamp":1335830400000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","goldjournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology"],"published-print":{"date-parts":[[2012,5]]},"DOI":"10.1016\/j.urology.2011.12.006","type":"journal-article","created":{"date-parts":[[2012,4,28]],"date-time":"2012-04-28T17:24:46Z","timestamp":1335633886000},"page":"1184.e1-1184.e6","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":74,"title":["Selenium and Lycopene Attenuate Cisplatin-induced Testicular Toxicity Associated With Oxidative Stress in Wistar Rats"],"prefix":"10.1016","volume":"79","author":[{"given":"Emad A.","family":"Salem","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Neveen A.","family":"Salem","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aref M.","family":"Maarouf","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ege Can","family":"Serefoglu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne J.G.","family":"Hellstrom","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2011.12.006_bib1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.etp.2009.02.066","article-title":"Caffeic acid phenethy 1 ester (CAPE) ameliorates cisplatin-induced hepatotoxicity in rabbit","volume":"62","author":"Kart","year":"2010","journal-title":"Exp Toxicol Pathol"},{"key":"10.1016\/j.urology.2011.12.006_bib2","doi-asserted-by":"crossref","first-page":"545","DOI":"10.1016\/j.urology.2009.05.024","article-title":"Antioxidative effect of royal jelly in cisplatin-induced testes damage","volume":"74","author":"Silici","year":"2009","journal-title":"Urology"},{"key":"10.1016\/j.urology.2011.12.006_bib3","doi-asserted-by":"crossref","first-page":"6","DOI":"10.1093\/jncimonographs\/lgi006","article-title":"Mechanisms of toxic damage to spermatogenesis","volume":"34","author":"Boekelheide","year":"2005","journal-title":"J Natl Cancer Inst Monogr"},{"key":"10.1016\/j.urology.2011.12.006_bib4","doi-asserted-by":"crossref","first-page":"115","DOI":"10.1016\/j.mrgentox.2004.08.010","article-title":"Cisplatin disrupts mammalian spermatogenesis, but does not affect recombination chromosome segregation","volume":"564","author":"Cherry","year":"2004","journal-title":"Mutat Res"},{"key":"10.1016\/j.urology.2011.12.006_bib5","doi-asserted-by":"crossref","first-page":"221","DOI":"10.1016\/j.tox.2003.10.012","article-title":"Selenium and high dose vitamin E administration protect cisplatin-induced oxidative damage to renal, liver and lens tissue in rats","volume":"195","author":"Naziroglu","year":"2004","journal-title":"Toxicology"},{"key":"10.1016\/j.urology.2011.12.006_bib6","first-page":"206","article-title":"The Role of Selenium in Nutrition","author":"Combs","year":"1986"},{"key":"10.1016\/j.urology.2011.12.006_bib7","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1016\/j.ygyno.2003.12.013","article-title":"Selenium as an element in the treatment of ovarian cancer in women receiving chemotherapy","volume":"93","author":"Sieja","year":"2004","journal-title":"Gynecol Oncol"},{"key":"10.1016\/j.urology.2011.12.006_bib8","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1016\/j.cbi.2005.12.009","article-title":"Free radicals, metals and antioxidants in oxidative stress-induced cancer","volume":"160","author":"Valko","year":"2006","journal-title":"Chem Biol Interact"},{"key":"10.1016\/j.urology.2011.12.006_bib9","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1016\/j.abb.2004.04.023","article-title":"Lycopene: methods of action to promote prostate health","volume":"430","author":"Wertz","year":"2004","journal-title":"Arch. Biochem. J Biol Phys"},{"key":"10.1016\/j.urology.2011.12.006_bib10","series-title":"Tomatoes, Lycopene and Human Health","first-page":"65","article-title":"Mechanism of action of lycopene","author":"Heber","year":"2006"},{"key":"10.1016\/j.urology.2011.12.006_bib11","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1111\/j.1745-7262.2008.00379.x","article-title":"Herbal extracts counteract cisplatin-mediated cell death in rat testis","volume":"10","author":"Amin","year":"2008","journal-title":"Asian J Androl"},{"key":"10.1016\/j.urology.2011.12.006_bib12","doi-asserted-by":"crossref","first-page":"200","DOI":"10.1016\/j.mefs.2010.07.001","article-title":"Histomorphometric effects of Kigelia africana (Bignoniaceae) fruit extract on the testis following short-term treatment with cisplatin in male Sprague-Dawley rats","volume":"15","author":"Azu","year":"2010","journal-title":"Middle East Fertil Soc J"},{"key":"10.1016\/j.urology.2011.12.006_bib13","doi-asserted-by":"crossref","first-page":"145","DOI":"10.1006\/phrs.2000.0724","article-title":"Effect of the antioxidants curcumin or selenium on cisplatin-induced nephrotoxicity and lipid peroxidation in rats","volume":"43","author":"Antunes","year":"2001","journal-title":"Pharmacol Res"},{"key":"10.1016\/j.urology.2011.12.006_bib14","first-page":"812","article-title":"Protective effect of sallylcysteine and lycopene in combination against N-methyl-N-nitro-N-nitrosoguanidine-induced genotoxicity","volume":"56","author":"Velmurugan","year":"2004","journal-title":"Pol J Pharmacol"},{"key":"10.1016\/j.urology.2011.12.006_bib15","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1016\/j.reprotox.2005.05.003","article-title":"Protective role of lycopene on cisplatin-induced changes in sperm characteristics, testicular damage and oxidative stress in rats","volume":"21","author":"Ate\u015f\u015fahin","year":"2006","journal-title":"Reprod Toxicol"},{"key":"10.1016\/j.urology.2011.12.006_bib16","doi-asserted-by":"crossref","first-page":"141","DOI":"10.1385\/BTER:93:1-3:141","article-title":"Nickel deficiency diminishes sperm quantity and movement in rats","volume":"91","author":"Yokoi","year":"2003","journal-title":"Biol Trace Elem Res"},{"key":"10.1016\/j.urology.2011.12.006_bib17","doi-asserted-by":"crossref","first-page":"2061","DOI":"10.1016\/j.theriogenology.2004.10.003","article-title":"The effect of ascorbic acid supplementation on sperm quality, lipid peroxidation and testosterone levels of male Wistar rats","volume":"63","author":"Sonmez","year":"2005","journal-title":"Theriogenology"},{"key":"10.1016\/j.urology.2011.12.006_bib18","doi-asserted-by":"crossref","first-page":"778","DOI":"10.1016\/j.theriogenology.2006.10.013","article-title":"Lycopene protects against cyclosporine A. induced testicular toxicity in rats","volume":"67","author":"T\u00fcrk","year":"2007","journal-title":"Theriogenology"},{"key":"10.1016\/j.urology.2011.12.006_bib19","doi-asserted-by":"crossref","first-page":"1474","DOI":"10.1016\/j.fertnstert.2007.04.059","article-title":"Improvement of cisplatin-induced injuries to sperm quality, the oxidant-antioxidant system and the histologic structure of the rat testis by ellagic acid","volume":"89","author":"Turk","year":"2008","journal-title":"Feril Steril"},{"key":"10.1016\/j.urology.2011.12.006_bib20","doi-asserted-by":"crossref","first-page":"351","DOI":"10.1016\/0003-2697(79)90738-3","article-title":"Assay for lipid peroxides in animal tissues by thiobarbituric acid reaction","volume":"95","author":"Ohkawa","year":"1979","journal-title":"Anal Biochem"},{"key":"10.1016\/j.urology.2011.12.006_bib21","doi-asserted-by":"crossref","first-page":"497","DOI":"10.1093\/clinchem\/34.3.497","article-title":"A simple method for clinical assay of superoxide dismutase","volume":"34","author":"Sun","year":"1988","journal-title":"Clin Chem"},{"key":"10.1016\/j.urology.2011.12.006_bib22","doi-asserted-by":"crossref","first-page":"70","DOI":"10.1016\/0003-9861(59)90090-6","article-title":"Tissue sulphydryl groups","volume":"82","author":"Ellman","year":"1959","journal-title":"Arch Biochem Biophys"},{"key":"10.1016\/j.urology.2011.12.006_bib23","series-title":"A Manual of Biochemical Methods.","first-page":"67","article-title":"Red cell metabolism","author":"Beutler","year":"1975"},{"key":"10.1016\/j.urology.2011.12.006_bib24","series-title":"Methods in Enzymatic Analysis","first-page":"276","article-title":"Catalase","author":"Aebi","year":"1983"},{"key":"10.1016\/j.urology.2011.12.006_bib25","doi-asserted-by":"crossref","first-page":"265","DOI":"10.1016\/S0021-9258(19)52451-6","article-title":"Protein measurement with folin phenol reagent","volume":"193","author":"Lowry","year":"1951","journal-title":"J Biol Chem"},{"key":"10.1016\/j.urology.2011.12.006_bib26","first-page":"459","article-title":"Testosterone and free thyroxin blood in congenitally acallosal male BALB\/cCF mice","volume":"24","author":"Mourao","year":"2003","journal-title":"N Eur Endocrinal Lett"},{"key":"10.1016\/j.urology.2011.12.006_bib27","doi-asserted-by":"crossref","first-page":"85","DOI":"10.1111\/j.1742-7843.2011.00688.x","article-title":"Persistent impairment of testicular histology and sperm motility in adult rats treated with cisplatin at peri-puberty","volume":"109","author":"Favareto","year":"2011","journal-title":"Basic Clin Pharmacol Toxicol"},{"key":"10.1016\/j.urology.2011.12.006_bib28","doi-asserted-by":"crossref","first-page":"1717","DOI":"10.1093\/humrep\/dep058","article-title":"Protective effect of curcumin in cisplatin-induced oxidative injury in rat testis: mitogen-activated protein kinase and nuclear factor\u2013kappa B signaling pathways","volume":"24","author":"Libey","year":"2009","journal-title":"Hum Reprod"},{"key":"10.1016\/j.urology.2011.12.006_bib29","doi-asserted-by":"crossref","first-page":"2436","DOI":"10.1248\/bpb.29.2436","article-title":"Protective effect of the ethanolic extract of the roots Brassica rapa on cisplatin-induced nephrotoxicity in LLC-PKl cells and rats","volume":"29","author":"Kim","year":"2006","journal-title":"Biol Bull"},{"key":"10.1016\/j.urology.2011.12.006_bib30","doi-asserted-by":"crossref","first-page":"2398","DOI":"10.1210\/endo-126-5-2398","article-title":"Mediated decrease in serum testosterone is associated with depression of luteinizing hormone receptors and cytohormone P-450 SCC in rat testis","volume":"126","author":"Maines","year":"1990","journal-title":"Endocrinology"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009042951102735X?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S009042951102735X?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T01:55:46Z","timestamp":1758765346000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S009042951102735X"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,5]]},"references-count":30,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2012,5]]}},"alternative-id":["S009042951102735X"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2011.12.006","relation":{},"ISSN":["0090-4295"],"issn-type":[{"value":"0090-4295","type":"print"}],"subject":[],"published":{"date-parts":[[2012,5]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Selenium and Lycopene Attenuate Cisplatin-induced Testicular Toxicity Associated With Oxidative Stress in Wistar Rats","name":"articletitle","label":"Article Title"},{"value":"Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urology.2011.12.006","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}