{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,6]],"date-time":"2025-11-06T12:04:06Z","timestamp":1762430646098,"version":"3.44.0"},"reference-count":26,"publisher":"Elsevier BV","issue":"4","license":[{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/tdm\/userlicense\/1.0\/"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/www.elsevier.com\/legal\/tdmrep-license"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-017"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-037"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-012"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-029"},{"start":{"date-parts":[[2012,10,1]],"date-time":"2012-10-01T00:00:00Z","timestamp":1349049600000},"content-version":"stm-asf","delay-in-days":0,"URL":"https:\/\/doi.org\/10.15223\/policy-004"}],"content-domain":{"domain":["clinicalkey.com","clinicalkey.com.au","clinicalkey.es","clinicalkey.fr","clinicalkey.jp","goldjournal.net","elsevier.com","sciencedirect.com"],"crossmark-restriction":true},"short-container-title":["Urology"],"published-print":{"date-parts":[[2012,10]]},"DOI":"10.1016\/j.urology.2012.06.004","type":"journal-article","created":{"date-parts":[[2012,7,31]],"date-time":"2012-07-31T07:34:30Z","timestamp":1343720070000},"page":"889-893","update-policy":"https:\/\/doi.org\/10.1016\/elsevier_cm_policy","source":"Crossref","is-referenced-by-count":19,"title":["Urodynamic Effects of Transrectal Intraprostatic Ona botulinum Toxin A Injections for Symptomatic Benign Prostatic Hyperplasia"],"prefix":"10.1016","volume":"80","author":[{"given":"Laetitia M.O.","family":"de Kort","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Esther T.","family":"Kok","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Trudy N.","family":"Jonges","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Peter F.W.M.","family":"Rosier","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J.L.H. Ruud","family":"Bosch","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"78","reference":[{"key":"10.1016\/j.urology.2012.06.004_bib1","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1111\/j.1464-410X.1995.tb07421.x","article-title":"The international prostate symptom score in a community-based sample of men between 55 and 74 years of age: prevalence and correlation of symptoms with age, prostate volume, flow rate and residual urine volume","volume":"75","author":"Bosch","year":"1995","journal-title":"Br J Urol"},{"issue":"Suppl 1","key":"10.1016\/j.urology.2012.06.004_bib2","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1046\/j.1464-410X.1998.0810s1029.x","article-title":"The pathophysiology of lower urinary tract symptoms in the ageing male population","volume":"81","author":"Lepor","year":"1998","journal-title":"Br J Urol"},{"key":"10.1016\/j.urology.2012.06.004_bib3","series-title":"European Association of Urology Guidelines","first-page":"1","article-title":"Guidelines on benign prostatic hyperplasia","author":"De la Rosette","year":"2008"},{"key":"10.1016\/j.urology.2012.06.004_bib4","doi-asserted-by":"crossref","first-page":"1896","DOI":"10.1097\/01.ju.0000049202.56189.54","article-title":"Effect of botulinum toxin A on the autonomic nervous system of the rat lower urinary tract","volume":"169","author":"Smith","year":"2003","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2012.06.004_bib5","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1002\/(SICI)1097-0045(19980915)37:1<44::AID-PROS7>3.0.CO;2-8","article-title":"Botox-induced prostatic involution","volume":"37","author":"Doggweiler","year":"1998","journal-title":"Prostate"},{"key":"10.1016\/j.urology.2012.06.004_bib6","doi-asserted-by":"crossref","first-page":"1158","DOI":"10.1016\/S0022-5347(05)00318-6","article-title":"Novel action of botulinum toxin on the stromal and epithelial components of the prostate gland","volume":"175","author":"Chuang","year":"2006","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2012.06.004_bib7","doi-asserted-by":"crossref","first-page":"582","DOI":"10.1016\/j.eururo.2007.03.002","article-title":"Effects of botulinum toxin A on the contractile function of dog prostate","volume":"52","author":"Lin","year":"2007","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2012.06.004_bib8","doi-asserted-by":"crossref","first-page":"12","DOI":"10.1186\/1471-2490-6-12","article-title":"Intraprostatic injection of botulinum toxin type-A relieves bladder outlet obstruction in human and induces prostate apoptosis in dogs","volume":"6","author":"Chuang","year":"2006","journal-title":"BMC Urol"},{"key":"10.1016\/j.urology.2012.06.004_bib9","doi-asserted-by":"crossref","first-page":"259","DOI":"10.1016\/S0090-4295(03)00477-1","article-title":"Relief by botulinum toxin of voiding dysfunction due to benign prostatic hyperplasia: results of a randomized, placebo-controlled study","volume":"62","author":"Maria","year":"2003","journal-title":"Urology"},{"key":"10.1016\/j.urology.2012.06.004_bib10","doi-asserted-by":"crossref","first-page":"775","DOI":"10.1016\/j.urology.2005.04.029","article-title":"Botulinum toxin type a improves benign prostatic hyperplasia symptoms in patients with small prostates","volume":"66","author":"Chuang","year":"2005","journal-title":"Urology"},{"key":"10.1016\/j.urology.2012.06.004_bib11","doi-asserted-by":"crossref","first-page":"670","DOI":"10.1016\/j.urology.2004.10.077","article-title":"Prostate botulinum A toxin injection\u2014an alternative treatment for benign prostatic obstruction in poor surgical candidates","volume":"65","author":"Kuo","year":"2005","journal-title":"Urology"},{"key":"10.1016\/j.urology.2012.06.004_bib12","doi-asserted-by":"crossref","first-page":"706","DOI":"10.3349\/ymj.2006.47.5.706","article-title":"Evaluation of short term clinical effects and presumptive mechanism of botulinum toxin type a as a treatment modality of benign prostatic hyperplasia","volume":"47","author":"Park","year":"2006","journal-title":"Yonsei Med J"},{"key":"10.1016\/j.urology.2012.06.004_bib13","doi-asserted-by":"crossref","first-page":"1033","DOI":"10.1111\/j.1464-410X.2006.06479.x","article-title":"Sustained beneficial effects of intraprostatic botulinum toxin type a on lower urinary tract symptoms and quality of life in men with benign prostatic hyperplasia","volume":"98","author":"Chuang","year":"2006","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2012.06.004_bib14","doi-asserted-by":"crossref","first-page":"153","DOI":"10.1016\/j.eururo.2007.08.050","article-title":"Intraprostatic botulinum toxin type a injection in patients unfit for surgery presenting with refractory urinary retention and benign prostatic enlargement","volume":"53","author":"Silva","year":"2008","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2012.06.004_bib15","doi-asserted-by":"crossref","first-page":"950","DOI":"10.1016\/S0929-6646(10)60008-3","article-title":"Botulinum toxin A injection to the bladder neck and urethra for medically refractory lower urinary tract symptoms in men without prostatic obstruction","volume":"108","author":"Chen","year":"2009","journal-title":"J Formos Med Assoc"},{"key":"10.1016\/j.urology.2012.06.004_bib16","doi-asserted-by":"crossref","first-page":"90","DOI":"10.1016\/j.urology.2008.08.475","article-title":"Relief by botulinum toxin of lower urinary tract symptoms owing to benign prostatic hyperplasia: early and long-term results","volume":"73","author":"Brisinda","year":"2009","journal-title":"Urology"},{"issue":"4 Suppl","key":"10.1016\/j.urology.2012.06.004_bib17","doi-asserted-by":"crossref","first-page":"649","DOI":"10.1016\/S0022-5347(09)61822-X","article-title":"12-Week results of a Fase II trial of 100 and 300 units botulinum neurotoxin type A (BoNT\/A) for the management of benign prostatic hyperplasia (BPH)","volume":"181","author":"Crawford","year":"2009","journal-title":"J Urol"},{"issue":"4 Suppl","key":"10.1016\/j.urology.2012.06.004_bib18","doi-asserted-by":"crossref","first-page":"650","DOI":"10.1016\/S0022-5347(09)61823-1","article-title":"Duration of the effects of a single intraprostatic injection of botulinum toxin type a in frail elderly patients with prostatic enlargement","volume":"181","author":"Silva","year":"2009","journal-title":"J Urol"},{"key":"10.1016\/j.urology.2012.06.004_bib19","doi-asserted-by":"crossref","first-page":"206","DOI":"10.1080\/00365590902811537","article-title":"Therapeutic effects of add-on botulinum toxin A on patients with large benign prostatic hyperplasia and unsatisfactory response to combined medical therapy","volume":"43","author":"Kuo","year":"2009","journal-title":"Scand J Urol Nephrol"},{"key":"10.1016\/j.urology.2012.06.004_bib20","doi-asserted-by":"crossref","first-page":"1950","DOI":"10.1111\/j.1464-410X.2010.09841.x","article-title":"Intraprostatic Botulinum toxin type A administration: evaluation of the effects on sexual function","volume":"107","author":"Silva","year":"2011","journal-title":"BJU Int"},{"key":"10.1016\/j.urology.2012.06.004_bib21","doi-asserted-by":"crossref","first-page":"1645","DOI":"10.1016\/j.eururo.2007.01.084","article-title":"Serum prostate-specific antigen as a predictor of prostate volume in the community: the Krimpen study","volume":"51","author":"Bohnen","year":"2007","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2012.06.004_bib22","doi-asserted-by":"crossref","first-page":"134","DOI":"10.1016\/j.eururo.2008.07.003","article-title":"Mechanisms of prostate atrophy after glandular botulinum neurotoxin type A injection: an experimental study in the rat","volume":"56","author":"Silva","year":"2009","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2012.06.004_bib23","doi-asserted-by":"crossref","first-page":"1379","DOI":"10.1016\/j.eururo.2007.11.026","article-title":"The relationship between prostate inflammation and lower urinary tract symptoms: examination of baseline data from the REDUCE trial","volume":"54","author":"Nickel","year":"2008","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2012.06.004_bib24","doi-asserted-by":"crossref","first-page":"475","DOI":"10.1111\/j.1365-2605.2009.00972.x","article-title":"Chronic inflammation in the pathogenesis of benign prostatic hyperplasia","volume":"33","author":"Fibbi","year":"2010","journal-title":"Int J Androl"},{"key":"10.1016\/j.urology.2012.06.004_bib25","doi-asserted-by":"crossref","first-page":"1522","DOI":"10.1016\/j.eururo.2007.03.034","article-title":"The long-term outcome of medical therapy for BPH","volume":"51","author":"Madersbacher","year":"2007","journal-title":"Eur Urol"},{"key":"10.1016\/j.urology.2012.06.004_bib26","doi-asserted-by":"crossref","first-page":"2034","DOI":"10.1016\/S0022-5347(01)68149-7","article-title":"Urodynamic effects of various treatment modalities for benign prostatic hyperplasia","volume":"158","author":"Bosch","year":"1997","journal-title":"J Urol"}],"container-title":["Urology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429512006383?httpAccept=text\/xml","content-type":"text\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/api.elsevier.com\/content\/article\/PII:S0090429512006383?httpAccept=text\/plain","content-type":"text\/plain","content-version":"vor","intended-application":"text-mining"}],"deposited":{"date-parts":[[2025,9,25]],"date-time":"2025-09-25T01:57:39Z","timestamp":1758765459000},"score":1,"resource":{"primary":{"URL":"https:\/\/linkinghub.elsevier.com\/retrieve\/pii\/S0090429512006383"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2012,10]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2012,10]]}},"alternative-id":["S0090429512006383"],"URL":"https:\/\/doi.org\/10.1016\/j.urology.2012.06.004","relation":{},"ISSN":["0090-4295"],"issn-type":[{"type":"print","value":"0090-4295"}],"subject":[],"published":{"date-parts":[[2012,10]]},"assertion":[{"value":"Elsevier","name":"publisher","label":"This article is maintained by"},{"value":"Urodynamic Effects of Transrectal Intraprostatic Ona botulinum Toxin A Injections for Symptomatic Benign Prostatic Hyperplasia","name":"articletitle","label":"Article Title"},{"value":"Urology","name":"journaltitle","label":"Journal Title"},{"value":"https:\/\/doi.org\/10.1016\/j.urology.2012.06.004","name":"articlelink","label":"CrossRef DOI link to publisher maintained version"},{"value":"article","name":"content_type","label":"Content Type"},{"value":"Copyright \u00a9 2012 Elsevier Inc. All rights reserved.","name":"copyright","label":"Copyright"}]}}